1,209 research outputs found
Theory of improved spectral purity in index patterned Fabry-Perot lasers
The spectral purity of a ridge waveguide Fabry-Perot laser can be improved by patterning the effective refractive index seen by an optical mode propagating in the cavity. Here we present a transmission matrix calculation to first order in the effective index step from which we derive the threshold condition as a function of cavity mode index. This approach enables us to solve the inverse problem relating the index pattern along the cavity to the threshold gain modulation in wavenumber space. Quasiperiodic index patterns are constructed, which lead to improved spectral purity at a predetermined wavelength. (c) 2005 American Institute of Physics. (DOI:10.1063/1.1919389
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A Quantitative Approach for Measuring Managerial Interfaces in the Development of a Capital Project
Capital projects are funded with the intention of meeting a business need. For
the delivery of the facility to be successful, the interface between the owner’s
business personnel and its project personnel must be effective. This paper outlines a
quantitative approach for the measurement of this management interface; an approach
which has not been accomplished to date. Although previous studies examined
various technical interfaces among project personnel, the interface between business
and project personnel is in fact, more important to ensuring the realization of the
project’s stated benefits. Therefore, this research conducted a thorough literature
review on studies related to organizational interfaces and their management in the
construction industry. It also examined quantitative measures of organizational
involvement and the interface between business and project units. This paper
concludes with some recommended quantitative assessment tools able to measure the
involvement and interaction between business and project personnel assigned to
develop a specific capital project.Civil, Architectural, and Environmental Engineerin
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Influence of capping groups on the synthesis of γ-Fe2O3 nanocrystals
Monodisperse and uniform γ-Fe_2O_3 (maghemite) nanocrystals of variable size were prepared by thermal decomposition of iron pentacarbonyl [Fe(CO)_5] in the presence of surfactants, following controlled oxidation with trimethylamine N-oxide as a mild oxidant. The influence of carboxylic acids with variable alkyl carbon chain lengths on the synthesis of γ-Fe_2O_3 nanocrystals was investigated. The effect of the molar ratios of surfactant to iron precursor was also studied. The nanocrystals were characterized by x-ray diffraction (XRD) and transmission electron microscopy (TEM). XRD showed the particles were highly crystalline at the nanometer scale. The results showed that the size and shape of the nanocrystal is strongly influenced by the decomposition temperature of iron pentacarbonyl and closely related to the length of carbon chain of the capping groups and the molar ratio of surfactant to iron precursor. Following controlled evaporation from nonpolar solvents, self-assembly into two-dimensional arrays could be observed by TEM. It was also found that the distance between the nanocrystals in self-assembled structures matched the length of the capping molecules very well
Growth of Lion and Puma Lentiviruses in Domestic Cat Cells and Comparisons with FIV
AbstractFeline immunodeficiency virus (FIV-Fca) is a lentivirus that causes gradual immunological deterioration in domestic cats. Lentiviruses related to FIV have been detected in several nondomestic feline species; the biologic significance of these viruses remains to be defined. To examine thein vitrocell tropism of these nondomestic cat lentiviruses, prototypical puma and lion lentiviruses (FIV-Pco and FIV-Ple) were cultured in a variety of feline cell cultures. A domestic cat T lymphoma cell line, 3201, best supported the replication of both FIV-Pco and FIV-Ple. Moreover, FIV-Ple was lytic for these cells. RT-PCR amplification of a conservedpolgene region demonstrated species-specific primer homology. Sequence and phylogenetic analyses of this amplification product confirmed the identity of the replicating viruses and classified two previously uncharacterized viruses within predictable lion and puma clades. Sequence analysis of a conservedpolregion demonstrated homology with previously characterized FIV-Ple and FIV-Pco. Western blot analysis using domestic cat anti-FIV-Fca sera showed that both FIV-Pco and FIV-Ple were antigenically related, to differing degrees, to three serotypes of FIV-Fca. These studies demonstrate that though nondomestic cat lentiviruses differ significantly from FIV-Fca and that a viral-specific protocol may be necessary for sensitive viral detection, these viruses can replicate in cells of domestic cats, suggesting the potential for cross-species transmission
Gold(I)-Catalyzed Nucleophilic Allylation of Azinium Ions with Allylboronates
Gold(I)-catalyzed nucleophilic allylations of pyridinium and quinolinium ions with allylboronates are reported. Transmetalation of the allylboronate with gold produces nucleophilic allylgold(I) species that add to the 4-position of the azinium ion with complete regioselectivity to give functionalized 1,4-dihydropyridines and 1,4-dihydroquinolines. Density functional theory (DFT) calculations provided mechanistic insight
Stellar Diameters and Temperatures. I. Main-Sequence A, F, and G Stars
We have executed a survey of nearby, main-sequence A-, F-, and G-type stars with the CHARA Array, successfully measuring the angular diameters of forty-four stars with an average precision of ~1.5%. We present new measures of the bolometric flux, which in turn leads to an empirical determination of the effective temperature for the stars observed. In addition, these CHARA-determined temperatures, radii, and luminosities are fit to Yonsei-Yale model isochrones to constrain the masses and ages of the stars. These results are compared to indirect estimates of these quantities obtained by collecting photometry of the stars and applying them to model atmospheres and evolutionary isochrones. We find that for most cases, the models overestimate the effective temperature by ~1.5%-4% when compared to our directly measured values. The overestimated temperatures and underestimated radii in these works appear to cause an additional offset in the star's surface gravity measurements, which consequently yield higher masses and younger ages, in particular for stars with masses greater than ~1.3 M_☉. Additionally, we compare our measurements to a large sample of eclipsing binary stars, and excellent agreement is seen within both data sets. Finally, we present temperature relations with respect to (B – V) and (V – K) colors as well as spectral type, showing that calibration of effective temperatures with errors ~1% is now possible from interferometric angular diameters of stars
The Vertebrate TLR Supergene Family Evolved Dynamically by Gene Gain/Loss and Positive Selection Revealing a Host-Pathogen Arms Race in Birds
The role of molecular testing and enzyme analysis in the management of hypomorphic citrullinemia
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69185/1/33256_ftp.pd
Transmission routes of rare seasonal diseases: the case of norovirus infections
Norovirus (NoV) is the most commonly recognized cause of acute gastroenteritis, with over a million cases globally per year. While usually self-limiting, NoV poses a substantial economic burden because it is highly contagious and there are multiple transmission routes. Infection occurs through inhalation of vomitus; faecal-oral spread; and food, water and environmental contamination. While the incidence of the disease is predictably seasonal, much less is known about the relative contribution of the various exposure pathways in causing disease. Additionally, asymptomatic excretion and viral shedding make forecasting disease burden difficult. We develop a novel stochastic dynamic network model to investigate the contributions of different transmission pathways in multiple coupled social networks representing schools, hospitals, care-homes and family households in a community setting. We analyse how the networks impact on transmission. We used ward-level demographic data from Northumberland, UK to create a simulation cohort. We compared the results with extant data on NoV cases from the IID2 study. Connectivity across the simulated cohort was high. Cases of NoV showed marked seasonality, peaking in early winter and declining through the summer. For the first time, we show that fomites and food appear to be the most important exposure routes in determining the population burden of disease. This article is part of the theme issue ‘Modelling infectious disease outbreaks in humans, animals and plants: epidemic forecasting and control’. This theme issue is linked with the earlier issue ‘Modelling infectious disease outbreaks in humans, animals and plants: approaches and important themes’
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