Linear electric field frequency shift (important for next generation electric dipole moment searches) induced in confined gases by a magnetic field gradient

The search for particle electric dipole moments (edm) represents a most promising way to search for physics beyond the standard model. A number of groups are planning a new generation of experiments using stored gases of various kinds. In order to achieve the target sensitivities it will be necessary to deal with the systematic error resulting from the interaction of the well-known $\overrightarrow{v}\times \overrightarrow{E}$ field with magnetic field gradients (often referred to as the geometric phase effect (Commins, ED; Am. J. Phys. \QTR{bf}{59}, 1077 (1991), Pendlebury, JM \QTR{em}{et al;} Phys. Rev. \QTR{bf}{A70}, 032102 (2004)). This interaction produces a frequency shift linear in the electric field, mimicking an edm. In this work we introduce an analytic form for the velocity auto-correlation function which determines the velocity-position correlation function which in turn determines the behavior of the frequency shift (Lamoreaux, SK and Golub, R; Phys. Rev \QTR{bf}{A71}, 032104 (2005)) and show how it depends on the operating conditions of the experiment. We also discuss some additional issues.Comment: 21 pages, 5 figure

Magnetotransport in Sr3PbO antiperovskite with three-dimensional massive Dirac electrons

Novel topological phenomena are anticipated for three-dimensional (3D) Dirac electrons. The magnetotransport properties of cubic ${\rm Sr_{3}PbO}$ antiperovskite, theoretically proposed to be a 3D massive Dirac electron system, are studied. The measurements of Shubnikov-de Haas oscillations and Hall resistivity indicate the presence of a low density ($\sim 1 \times 10^{18}$ ${\rm cm^{-3}}$) of holes with an extremely small cyclotron mass of 0.01-0.06$m_{e}$. The magnetoresistance $\Delta\rho_{xx}(B)$ is linear in magnetic field $B$ with the magnitude independent of temperature. These results are fully consistent with the presence of 3D massive Dirac electrons in ${\rm Sr_{3}PbO}$. The chemical flexibility of the antiperovskites and our findings in the family member, ${\rm Sr_{3}PbO}$, point to their potential as a model system in which to explore exotic topological phases

Twenty-six new species of Hoploscopa (Lepidoptera, Crambidae) from South-East Asia revealed by morphology and DNA barcoding

Hoploscopa Meyrick (Lepidoptera: Crambidae) is a fern-feeding genus found in montane areas of South-East Asia and Melanesia, eastwards up to the Samoan Islands. It includes sixteen described species, with at least 70 further undescribed species known from scientific collections. An iterative approach including morphological and molecular characters was used in order to explore the diversity of Hoploscopa. The hitherto described species are revised, and descriptions authored by T. Léger and M. Nuss are provided for an additional 26 new species: H. agtuuganonensis sp. nov., H. albipuncta sp. nov., H. albomaculata sp. nov., H. anacantha sp. nov., H. boleta sp. nov., H. cynodonta sp. nov., H. danaoensis sp. nov., H. gombongi sp. nov., H. gracilis sp. nov., H. ignitamaculae sp. nov., H. isarogensis sp. nov., H. jubata sp. nov., H. kelama sp. nov., H. kinabaluensis sp. nov., H. mallyi sp. nov., H. marijoweissae sp. nov., H. matheae sp. nov., H. niveofascia sp. nov., H. pangrangoensis sp. nov., H. parvimacula sp. nov., H. pseudometacrossa sp. nov., H. sepanggi sp. nov., H. sumatrensis sp. nov., H. titika sp. nov., H. tonsepi sp. nov., H. ypsilon sp. nov. Using a protocol specific for the amplification of DNA from old museum specimens, we recovered 101 COI barcodes for all but one of the newly described species, with 76 being barcode compliant (>487 bp). Species delimitation analyses suggest cryptic diversity, with six cases reflecting allopatric divergence, and two further cases found in sympatry

Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila

In Drosophila, 50 classes of olfactory receptor neurons (ORNs) connect to 50 class-specific and uniquely positioned glomeruli in the antennal lobe. Despite the identification of cell surface receptors regulating axon guidance, how ORN axons sort to form 50 stereotypical glomeruli remains unclear. Here we show that the heterophilic cell adhesion proteins, DIPs and Dprs, are expressed in ORNs during glomerular formation. Many ORN classes express a unique combination of DIPs/dprs, with neurons of the same class expressing interacting partners, suggesting a role in class-specific self-adhesion between ORN axons. Analysis of DIP/Dpr expression revealed that ORNs that target neighboring glomeruli have different combinations, and ORNs with very similar DIP/Dpr combinations can project to distant glomeruli in the antennal lobe. DIP/Dpr profiles are dynamic during development and correlate with sensilla type lineage for some ORN classes. Perturbations of DIP/dpr gene function result in local projection defects of ORN axons and glomerular positioning, without altering correct matching of ORNs with their target neurons. Our results suggest that context-dependent differential adhesion through DIP/Dpr combinations regulate self-adhesion and sort ORN axons into uniquely positioned glomeruli

Analysis of strength and vibration characteristics of the first working blades of an axial compressor with rotor groove

В данной работе представлен сравнительный анализ результатов модального и структурного расчетов единичной лопатки первой ступени осевого компрессора и лопатки в сборке с пазом. Произведена верификация частот собственных колебаний. Выявлены зоны локализации интенсивностей напряжений при нагружении центробежными силами для различных конструктивных исполнений лопаточного аппарата турбокомпрессора. Показаны возможности снижения напряжений путем выбора наиболее удачной конструкции.This paper presents a comparative analysis of the results of the modal and structural calculations individual blade of the first stage axial compressor and blade assembly to the groove. Verification of the natural frequencies was produced. Identified areas of localization of the intensities of stresses when loaded by centrifugal forces for various design versions of the blade apparatus of the turbocharger. Shown the possibility of reducing stress by selecting the most successful design

Optical gap in herringbone and pi-stacked crystals of 1]benzothieno3,2-b]benzothiophene and its brominated derivative

The optical gap of the organic semiconductor 1]benzothieno3,2-b]benzothiophene and its 2,7-dibrominated analogue is measured in solution and in the crystalline state by means of UV-vis and emission spectroscopy. Bromination leads to a change in molecular packing from herringbone to pi-stacked, resulting in a marked shift in the absorption and emission spectra which is found to be in accordance with TDDFT calculations

N‐Substituted Nipecotic Acids as (S )‐SNAP‐5114 Analogues with Modified Lipophilic Domains

Potential mGAT4 inhibitors derived from the lead substance (S )‐SNAP‐5114 have been synthesized and characterized for their inhibitory potency. Variations from the parent compound included the substitution of one of its aromatic 4‐methoxy and 4‐methoxyphenyl groups, respectively, with a more polar moiety, including a carboxylic acid, alcohol, nitrile, carboxamide, sulfonamide, aldehyde or ketone function, or amino acid partial structures. Furthermore, it was investigated how the substitution of more than one of the aromatic 4‐methoxy groups affects the potency and selectivity of the resulting compounds. Among the synthesized test substances (S )‐1‐{2‐[(4‐formylphenyl)bis(4‐methoxyphenyl)‐methoxy]ethyl}piperidine‐3‐carboxylic acid, that features a carbaldehyde function in place of one of the aromatic 4‐methoxy moieties of (S )‐SNAP‐5114, was found to have a pIC50 value of 5.89±0.07, hence constituting a slightly more potent mGAT4 inhibitor than the parent substance while showing comparable subtype selectivity

Recovery of low volumes of wear debris from rat stifle joint tissues using a novel particle isolation method

Less than optimal particle isolation techniques have impeded analysis of orthopaedic wear debris in vivo. The purpose of this research was to develop and test an improved method for particle isolation from tissue. A volume of 0.018 mm³ of clinically relevant CoCrMo, Ti-6Al-4V or Si₃N₄ particles was injected into rat stifle joints for seven days of in vivo exposure. Following sacrifice, particles were located within tissues using histology. The particles were recovered by enzymatic digestion of periarticular tissue with papain and proteinase K, followed by ultracentrifugation using a sodium polytungstate density gradient. Particles were recovered from all samples, observed using SEM and the particle composition was verified using EDX, which demonstrated that all isolated particles were free from contamination. Particle size, aspect ratio and circularity were measured using image analysis software. There were no significant changes to the measured parameters of CoCrMo or Si₃N₄ particles before and after the recovery process (KS tests, p > 0.05). Titanium particles were too few before and after isolation to analyse statistically, though size and morphologies were similar. Overall the method demonstrated a significant improvement to current particle isolation methods from tissue in terms of sensitivity and efficacy at removal of protein, and has the potential to be used for the isolation of ultra-low wearing total joint replacement materials from periprosthetic tissues

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic anaplasmosis, babesiosis and other diseases. The large genome reflects accumulation of repetitive DNA, new lineages of retro-transposons, and gene architecture patterns resembling ancient metazoans rather than pancrustaceans. Annotation of scaffolds representing approximately 57% of the genome, reveals 20,486 protein-coding genes and expansions of gene families associated with tick-host interactions. We report insights from genome analyses into parasitic processes unique to ticks, including host \u27questing\u27, prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin digestion, haem detoxification, vitellogenesis and prolonged off-host survival. We identify proteins associated with the agent of human granulocytic anaplasmosis, an emerging disease, and the encephalitis-causing Langat virus, and a population structure correlated to life-history traits and transmission of the Lyme disease agent

Cost-Effective Reciprocating Engine Emissions Control and Monitoring for E&P Field and Gathering Engines

This report highlights work done on a project intended to lower the cost of environmental compliance and expedite project permitting for Exploration and Production (E&P) operators by identifying, developing, testing, and commercializing emissions control and monitoring technologies. Promising technologies have already been identified and developed. Current work focuses on testing these promising technologies. Specifically, several technologies are being tested in the laboratory for application to lean-burn engines or fully characterized on-site for use with rich-burn engines. Upon completion of these tests, the most cost-effective and robust technologies will be tested in the field and commercialization will ensue. During this quarter, progress in laboratory testing for lean-burn engines was limited by maintenance issues on the KSU Ajax DP-115. The difficulties that required maintenance to be performed will likely require that the 180 psig prototype valve be tested in the future, if possible. The maintenance was performed, and it is expected that the Ajax will be available for testing in the coming quarter. Although laboratory testing was slowed as a result of maintenance issues, progress in experimental characterization of technologies has been significant. NSCR systems will be characterized as applied to rich-burn engines on-site. This characterization will ensure high-quality data in final field testing on rich-burn engines and is considered to be essential, despite that the work requires the delay of official field testing until 2008. Many preliminary and administrative tasks have been completed, including initial site selection, official proposal submittal, and beginning a process to approve necessary changes to installed field engines