Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years.

This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal incontinence

Matrix Adhesion Polarizes Heart Progenitor Induction In The Invertebrate Chordate Ciona Intestinalis

Cell-matrix adhesion strongly influences developmental signaling. Resulting impacts on cell migration and tissue morphogenesis are well characterized. However, the in vivo impact of adhesion on fate induction remains ambiguous. Here, we employ the invertebrate chordate Ciona intestinalis to delineate an essential in vivo role for matrix adhesion in heart progenitor induction. In Ciona pre-cardiac founder cells, invasion of the underlying epidermis promotes localized induction of the heart progenitor lineage. We found that these epidermal invasions are associated with matrix adhesion along the pre-cardiac cell/epidermal boundary. Through targeted manipulations of RAP GTPase activity, we were able to manipulate pre-cardiac cell-matrix adhesion. Targeted disruption of pre-cardiac cell-matrix adhesion blocked heart progenitor induction. Conversely, increased matrix adhesion generated expanded induction. We were also able to selectively restore cell-matrix adhesion and heart progenitor induction through targeted expression of Ci-Integrin β2. These results indicate that matrix adhesion functions as a necessary and sufficient extrinsic cue for regional heart progenitor induction. Furthermore, time-lapse imaging suggests that cytokinesis acts as an intrinsic temporal regulator of heart progenitor adhesion and induction. Our findings highlight a potentially conserved role for matrix adhesion in early steps of vertebrate heart progenitor specification

Energy Requirement of Control: Comments on Szilard's Engine and Maxwell's Demon

In mathematical physical analyses of Szilard's engine and Maxwell's demon, a general assumption (explicit or implicit) is that one can neglect the energy needed for relocating the piston in Szilard's engine and for driving the trap door in Maxwell's demon. If this basic assumption is wrong, then the conclusions of a vast literature on the implications of the Second Law of Thermodynamics and of Landauer's erasure theorem are incorrect too. Our analyses of the fundamental information physical aspects of various type of control within Szilard's engine and Maxwell's demon indicate that the entropy production due to the necessary generation of information yield much greater energy dissipation than the energy Szilard's engine is able to produce even if all sources of dissipation in the rest of these demons (due to measurement, decision, memory, etc) are neglected.Comment: New, simpler and more fundamental approach utilizing the physical meaning of control-information and the related entropy production. Criticism of recent experiments adde

Stylet-Bearing Nematodes Associated with Plants in Iowa Prairies

Native Iowa prairies contained a plant parasitic nematode population which differed markedly in predominant species from populations in cultivated fields. Nematode species and their abundance varied among the five prairies sampled. Aorolaimus was common in most prairies, but is not known in Iowa cultivated soils. Tylenchorhynchus maximus was common in the Kalsow and Sheeder prairies, but was not found in the Cayler and Hayden prairies. Helicotylenchus was common in all prairies, but the species were unevenly distributed

On Norton’s “…Shook…” and Myrvold’s “Shakin’…”

Norton’s and Myrvold’s recent analyses of fluctuations and Landauer’s principle are compatible

Nematodes and Fungi Are Cutting Hay Yields

Because of parasitic nematodes and fungi many Iowa farmers are not getting nearly the quantity of hay that alfalfa is capable of producing. Hay losses from these pests and diseases cost several million dollars annually

Evidence for polar jets as precursors of polar plume formation

Observations from the Hinode/XRT telescope and STEREO/SECCHI/EUVI are utilized to study polar coronal jets and plumes. The study focuses on the temporal evolution of both structures and their relationship. The data sample, spanning April 7-8 2007, shows that over 90% of the 28 observed jet events are associated with polar plumes. EUV images (STEREO/SECCHI) show plume haze rising from the location of approximately 70% of the polar X-ray (Hinode/XRT) and EUV jets, with the plume haze appearing minutes to hours after the jet was observed. The remaining jets occurred in areas where plume material previously existed causing a brightness enhancement of the latter after the jet event. Short-lived, jet-like events and small transient bright points are seen (one at a time) at different locations within the base of pre-existing long-lived plumes. X-ray images also show instances (at least two events) of collimated-thin jets rapidly evolving into significantly wider plume-like structures that are followed by the delayed appearance of plume haze in the EUV. These observations provide evidence that X-ray jets are precursors of polar plumes, and in some cases cause brightenings of plumes. Possible mechanisms to explain the observed jet and plume relationship are discussed.Comment: 10 pages, 4 figures, accepted as APJ Lette

Applications of the AVE-Sesame data sets to mesoscale studies

Data collected by the lightning data concentrator are available for research. The Mark 3 McIDAS capability provides greater flexibility for the Marshall user community and serves as a model of future UW McIDAS to remote computer links. Techniques were investigated for the display of dynamic 3-D data sets. To date the most promising display technology is a polarized two CRT perspective display which allows both dynamic 3-D images and graphics presentations with full color capability. Algorithms were for the preparation and display of conventional and satellite based weather data in 3-D. These include gridding, contouring, and streamlining processors which operate on both real time and case study data bases. An upper air trajectory model was implemented which creates a display of air parcel trajectories in perspective 3-D. A subsystem for the generation of 3-D solid surface display with shading and hidden surface display with shading and hidden surface removal was tested and its products are currently being evaluated. Motion parallax introduced by moving the point of observation during display is an important depth cue, which, when added to the perspective parallax creates a very realistic appearing display

Plant-Parasitic Nematodes in Iowa: Longidoridae and Trichodoriadae

Plant-parasitic nematodes, although common, are little known in Iowa. Many are important plant pathogens. This paper documents the nine species of Longidoridae and Trichodoridae known in Iowa. These are Longidorus breviannulatus, L. crassus, L. macromucronatus, L. sylphus, Xiphinema americanum, X. bakeri, X. chambersi, Paratrichodorus minor, and Trichodorus proximus

One, two, or three stars? An investigation of an unusual eclipsing binary candidate undergoing dramatic period changes

We report our investigation of 1SWASP J234401.81-212229.1, a variable with a 18 461.6 s period. After identification in a 2011 search of the SuperWASP archive for main-sequence eclipsing binary candidates near the distribution's short-period limit of ~0.20 d, it was measured to be undergoing rapid period decrease in our earlier work, though later observations supported a cyclic variation in period length. Spectroscopic data obtained in 2012 with the Southern African Large Telescope did not, however, support the interpretation of the object as a normal eclipsing binary. Here, we consider three possible explanations consistent with the data: a single-star oblique rotator model in which variability results from stable cool spots on opposite magnetic poles; a two-star model in which the secondary is a brown dwarf; and a three-star model involving a low-mass eclipsing binary in a hierarchical triple system. We conclude that the latter is the most likely model