Platycorypha nigrivirga Burckhardt (Hemiptera: Sternorrhyncha: Psylloidea), tipu psyllid, new to North America

The tipu psyllid, Platycorypha nigrivirga Burckhardt (Hemiptera: Sternorrhyncha: Psylloidea), is reported for the first time in North America (USA: California). Diagnostic characters for identification of adults and nymphs, host and damage data, and known distribution are given

Holism and non-separability applied to quantum mechanics

Einstein was never satisfied with quantum mechanics. He argued that quantum mechanics was incomplete for two main reasons; it violated the locality principle and the separability principle. The violation of separability is an unavoidable consequence of quantum interactions. Non-separability can be seen in quantum entanglement. Non-locality, however, is more controversial. Einstein and his associates published the EPR paper in order to argue for the incompleteness of quantum mechanics. Years later, John Bell formulated what became known as the Bell Inequalities in response to the EPR paper. The Bell Inequalities are seen as a major obstacle for quantum locality. I will argue that non-locality is not a necessary implication of the Bell Inequalities. The Bell Inequalities were developed using Bell’s locality requirement as a major premise. Bell’s locality requirement can be described in terms of two conditions, parameter independence and outcome independence. A violation of either condition will lead to a violation of the Bell inequalities. Parameter independence is not violated by the results of experimental quantum physics. So, it can be argued that violations of the Bell inequalities are caused by the violation of outcome independence. Such a violation of outcome independence does not imply non-locality if we accept some form of holism or non-separability. Thus, by including some form of holism or non-separability into our picture of the quantum realm we can develop a theory that does not conflict with locality. This paper will discuss different types of holism and non-separability and how they can be used to help understand quantum phenomena

Permanent Closure of MFC Biodiesel Underground Storage Tank 99ANL00013

This closure package documents the site assessment and permanent closure of the Materials and Fuels Complex biodiesel underground storage tank 99ANL00013 in accordance with the regulatory requirements established in 40 CFR 280.71, “Technical Standards and Corrective Action Requirements for Owners and Operators of Underground Storage Tanks: Out-of-Service UST Systems and Closure.

The Interaction of Action-Inaction Goals and Approach-Avoidance Motivations: Implications for Healthy Food Marketing.

Action-inaction goals and approach-avoidance motivations are two related constructs that are frequently confounded in both theory and practice. By definition, general action and inaction goals influence the amount of motor or cognitive output an individual desires and approach and avoidance motivations speak to the direction of behavior towards or away from a stimulus. This dissertation posits that these two frequently confounded constructs are actually orthogonal dimensions that provide information about the volume and direction of goal-driven behavior, respectively. Across five studies, this dissertation examined the orthogonal nature of action-inaction goals and approach-avoidance motivations. Furthermore, this dissertation explored the implications of separately manipulating these two constructs in the context of persuasive communications designed to encourage healthy eating. Results indicate that action-inaction goals and approach-avoidance motivations are both theoretically and practically distinct concepts. In addition, the interaction between action-inaction goals and approach-avoidance motivations has important implications for goal pursuit and public health messaging.PhDPsychologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/110474/1/cacarino_1.pd

Performance measures funding : the journey of one Washington Community College

The study was designed to gain an understanding of the implementation of Performance Measures Funding at one Washington State community college. The research participants included the nine individuals who were charged with the design and implementation of the college's Improvement Plan, which addressed the four legislatively, prescribed goals outlined in the 1997-1999 Washington Appropriations Act. The researcher was interested in understanding how this new funding mandate was viewed and dealt with from the community college campus perspective. Each participant responded to open-ended interview questions administered by the researcher. This qualitative, phenomenological study resulted in gaining insights into the shared experience of the nine participants, so that the implementation of this state mandate could be better understood as told by the participants whose role was that of the "implementers." Data analysis was completed using a five-step process common to phenomenological research. As a result, three themes emerged: power, design flaw, lessons learned. The findings indicate that the legislature should have involved the community college system in the design of the Performance Measures Funding program and that greater consideration should have been given to the time necessary to design and implement improvement efforts that had lasting impact. Assessment of the program at the campus and state level was lacking

О соотношении между психическими состояними, кровообращением и дыханием : плетисмографическое исследование душевно-больных : диссертация на степень доктора медицины

http://tartu.ester.ee/record=b2113616~S1*es

Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner.

BackgroundRewriting of the epigenome has risen as a promising alternative to gene editing for precision medicine. In nature, epigenetic silencing can result in complete attenuation of target gene expression over multiple mitotic divisions. However, persistent repression has been difficult to achieve in a predictable manner using targeted systems.ResultsHere, we report that persistent epigenetic memory required both a DNA methyltransferase (DNMT3A-dCas9) and a histone methyltransferase (Ezh2-dCas9 or KRAB-dCas9). We demonstrate that the histone methyltransferase requirement can be locus specific. Co-targeting Ezh2-dCas9, but not KRAB-dCas9, with DNMT3A-dCas9 and DNMT3L induced long-term HER2 repression over at least 50 days (approximately 57 cell divisions) and triggered an epigenetic switch to a heterochromatic environment. An increase in H3K27 trimethylation and DNA methylation was stably maintained and accompanied by a sustained loss of H3K27 acetylation. Interestingly, substitution of Ezh2-dCas9 with KRAB-dCas9 enabled long-term repression at some target genes (e.g., SNURF) but not at HER2, at which H3K9me3 and DNA methylation were transiently acquired and subsequently lost. Off-target DNA hypermethylation occurred at many individual CpG sites but rarely at multiple CpGs in a single promoter, consistent with no detectable effect on transcription at the off-target loci tested. Conversely, robust hypermethylation was observed at HER2. We further demonstrated that Ezh2-dCas9 required full-length DNMT3L for maximal activity and that co-targeting DNMT3L was sufficient for persistent repression by Ezh2-dCas9 or KRAB-dCas9.ConclusionsThese data demonstrate that targeting different combinations of histone and DNA methyltransferases is required to achieve maximal repression at different loci. Fine-tuning of targeting tools is a necessity to engineer epigenetic memory at any given locus in any given cell type

NMR evidence for inhomogeneous glassy behavior driven by nematic fluctuations in iron arsenide superconductors

We present $^{75}$As nuclear magnetic resonance spin-lattice and spin-spin relaxation rate data in Ba(Fe$_{1-x}$Co$_x$)$_2$As$_2$ and Ba(Fe$_{1-x}$Cu$_x$)$_2$As$_2$ as a function of temperature, doping and magnetic field. The relaxation curves exhibit a broad distribution of relaxation rates, consistent with inhomogeneous glassy behavior up to 100 K. The doping and temperature response of the width of the dynamical heterogeneity is similar to that of the nematic susceptibility measured by elastoresistance measurements. We argue that quenched random fields which couple to the nematic order give rise to a nematic glass that is reflected in the spin dynamics.Comment: Accepted to Physical Review