Muskuläre Biomechanik in der Sprunggelenkprothetik

Zusammenfassung: Das Ziel dieser orthopädisch-biomechanischen Studie war die Evaluation der Muskelfunktion von Patienten, bei welchen infolge unilateraler, schwerer Arthrose am oberen Sprunggelenk (OSG) eine Prothese eingesetzt wurde. Bei 10Patienten wurde vor und 1Jahr nach Implantation einer OSG-Prothese eine orthopädische und biomechanische Untersuchung durchgeführt. Dabei wurden der Schmerzscore, der "American Orthopaedic Foot and Ankle Society"- (AOFAS-)Ankle-Score, der Bewegungsumfang (ROM) des Sprunggelenks und der Unterschied zwischen dem Umfang des Unterschenkels des betroffenen und des kontralateralen gesunden Beins gemessen. Die biomechanische Beurteilung bestand aus einer simultanen Messung des maximal willkürlichen, isometrischen Drehmoments bei Plantarflexion und Dorsalextension des OSG sowie aus einem Oberflächenelektromyogramm (EMG; mittlere Frequenz und Intensität) von 4 Unterschenkelmuskeln: Tibialis anterior (TA), Gastrocnemius medialis (GM), Soleus (SO) und Peroneus longus (PL). Im Vergleich zur präoperativen Evaluation verbesserten sich der Schmerzscore von 6,7 auf 0,8Punkte, der AOFAS-Ankle-Score von 35,6 auf 92,3Punkte und der ROM nach Implantation der OSG-Prothese signifikant. Die mittlere Differenz des Unterschenkelumfangs zwischen den beiden Beinen nahm von 2,2cm auf 1,4cm ab. Dies war jedoch nicht signifikant. Das mittlere Drehmoment des betroffenen Sprunggelenks bei Dorsalextension stieg von 17,0 auf 25,8Nm und bei Plantarflexion von 15,7 auf 24,6Nm signifikant an. Bei der 1-Jahres-Nachkontrolle war die mittlere EMG-Frequenz in allen atrophischen Muskeln tiefer als bei den gesunden Muskeln der kontralateralen Seite. Ein Unterschied der mittleren EMG-Intensität zur kontralateralen gesunden Seite konnte nicht verifiziert werden. Daraus kann gefolgert werden, dass Patienten mit symptomatischer OSG-Arthrose mit einer Prothese eine bessere Funktion erlangen; 1Jahr nach der Operation entspricht dies jedoch nicht dem Ausmaß derjenigen des kontralateralen gesunden Bein

An Introduction to Superconducting Qubits and Circuit Quantum Electrodynamics

A subset of the concepts of circuit quantum electrodynamics are reviewed as a reference to the Axion Dark Matter Experiment (ADMX) community as part of the proceedings of the 2nd Workshop on Microwave Cavities and Detectors for Axion Research. The classical Lagrangians and Hamiltonians for an LC circuit are discussed along with black box circuit quantization methods for a weakly anharmonic qubit coupled to a resonator or cavity

The preferred movement path paradigm: influence of running shoes on joint movement

PURPOSE: (a) to quantify differences in lower extremity joint kinematics for groups of runners subjected to different running footwear conditions, and (b) to quantify differences in lower extremity joint kinematics on an individual basis for runners subjected to different running footwear conditions. METHODS: Three-dimensional ankle and knee joint kinematics were collected for 35 heel-toe runners when wearing three different running shoes and when running barefoot. Absolute mean differences in ankle and knee joint kinematics were computed between running shoe conditions. The percentage of individual runners who displayed differences below a 2°, 3° and 5° threshold were also calculated. RESULTS: The results indicate that the mean kinematics of the ankle and knee joints were similar between running shoe conditions. Aside from ankle dorsi-flexion and knee flexion, the percentage of runners maintaining their movement path between running shoes (i.e. less than 3°) was in the order of magnitude of about 80 to 100%. Many runners showed ankle and knee joint kinematics that differed between a conventional running shoe and barefoot by more than 3°, especially for ankle dorsiflexion and knee flexion CONCLUSION: Many runners stay in the same movement path (the preferred movement path) when running in various different footwear conditions. The percentage of runners maintaining their preferred movement path depends on the magnitude of the change introduced by the footwear condition

Universal detector efficiency of a mesoscopic capacitor

We investigate theoretically a novel type of high frequency quantum detector based on the mesoscopic capacitor recently realized by Gabelli et al., [Science {\bf 313}, 499 (2006)], which consists of a quantum dot connected via a single channel quantum point contact to a single lead. We show that the state of a double quantum dot charge qubit capacitively coupled to this detector can be read out in the GHz frequency regime with near quantum limited efficiency. To leading order, the quantum efficiency is found to be universal owing to the universality of the charge relaxation resistance of the mesoscopic capacitor.Comment: 4 pages, 2 figures, submitted to PR

3-D kinematic comparison of treadmill and overground running.

Studies investigating the mechanics of human movement are often conducted using the treadmill. The treadmill is an attractive device for the analysis of human locomotion. Studies comparing overground and treadmill running have analyzed discrete variables, however differences in excursion from footstrike to peak angle and range of motion during stance have yet to be examined. This study aimed to examine the 3-D kinematics of the lower extremities during overground and treadmill locomotion to determine the extent to which the two modalities differ. Twelve participants ran at 4.0m/s in both treadmill and overground conditions. 3-D angular kinematic parameters during the stance phase were collected using an eight camera motion analysis system. Hip, knee and ankle joint kinematics were quantified in the sagittal, coronal and transverse planes, then compared using paired t-tests. Of the parameters analyzed hip flexion at footstrike 12° hip range of motion 17°, peak hip flexion 12.7°, hip transverse plane range of motion 8° peak knee flexion 5° and peak ankle excursion range 6.6°, coronal plane ankle angle at toe-off 6.5° and peak ankle eversion 6.3° were found to be significantly different. These results lead to the conclusion that the mechanics of treadmill locomotion cannot be generalized to overground

The Influence of Foot Positioning on Ankle Sprains

The goal of this study was to examine the influence of changes in foot positioning at touch-down on ankle sprain occurrence. Muscle model driven computer simulations of 10 subjects performing the landing phase of a side-shuffle movement were performed. The relative subtalar joint and talocural joint angles at touchdown were varied, and each subject-specific simulation was exposed to a set of perturbed floor conditions. The touchdown subtalar joint angle was not found to have a considerable influence on sprain occurrence, while increased touchdown plantar flexion caused increased ankle sprain occurrences. Increased touchdown plantar flexion may be the mechanism which causes ankles with a history of ankle sprains to have an increased susceptibility to subsequent sprains. This finding may also reveal a mechanism by which taping of a sprained ankle or the application of an ankle brace leads to decreased ankle sprain susceptibility

EXTENSION OF THE 1D FOUR-GROUP ANALYTIC NODAL METHOD TO FULL MULTIGROUP

In the mid 80’s, a four-group/two-region, entirely analytical 1D nodal benchmark appeared. It was readily acknowledged that this special case was as far as one could go in terms of group number and still achieve an analytical solution. In this work, we show that by decomposing the solution to the multigroup diffusion equation into homogeneous and particular solutions, extension to any number of groups is a relatively straightforward exercise using the mathematics of linear algebra

Implementing and characterizing precise multi-qubit measurements

There are two general requirements to harness the computational power of quantum mechanics: the ability to manipulate the evolution of an isolated system and the ability to faithfully extract information from it. Quantum error correction and simulation often make a more exacting demand: the ability to perform non-destructive measurements of specific correlations within that system. We realize such measurements by employing a protocol adapted from [S. Nigg and S. M. Girvin, Phys. Rev. Lett. 110, 243604 (2013)], enabling real-time selection of arbitrary register-wide Pauli operators. Our implementation consists of a simple circuit quantum electrodynamics (cQED) module of four highly-coherent 3D transmon qubits, collectively coupled to a high-Q superconducting microwave cavity. As a demonstration, we enact all seven nontrivial subset-parity measurements on our three-qubit register. For each we fully characterize the realized measurement by analyzing the detector (observable operators) via quantum detector tomography and by analyzing the quantum back-action via conditioned process tomography. No single quantity completely encapsulates the performance of a measurement, and standard figures of merit have not yet emerged. Accordingly, we consider several new fidelity measures for both the detector and the complete measurement process. We measure all of these quantities and report high fidelities, indicating that we are measuring the desired quantities precisely and that the measurements are highly non-demolition. We further show that both results are improved significantly by an additional error-heralding measurement. The analyses presented here form a useful basis for the future characterization and validation of quantum measurements, anticipating the demands of emerging quantum technologies.Comment: 10 pages, 5 figures, plus supplemen

Assessment of 24-hour physical behaviour in children and adolescents via wearables: a systematic review of free-living validation studies.

Objectives Studies that assess all three dimensions of the integrative 24-hour physical behaviour (PB) construct, namely, intensity, posture/activity type and biological state, are on the rise. However, reviews on validation studies that cover intensity, posture/activity type and biological state assessed via wearables are missing. Design Systematic review. The risk of bias was evaluated by using the QUADAS-2 tool with nine signalling questions separated into four domains (ie, patient selection/study design, index measure, criterion measure, flow and time). Data sources Peer-reviewed validation studies from electronic databases as well as backward and forward citation searches (1970-July 2021). Eligibility criteria for selecting studies Wearable validation studies with children and adolescents (age <18 years). Required indicators: (1) study protocol must include real-life conditions; (2) validated device outcome must belong to one dimension of the 24-hour PB construct; (3) the study protocol must include a criterion measure; (4) study results must be published in peer-reviewed English language journals. Results Out of 13 285 unique search results, 76 articles with 51 different wearables were included and reviewed. Most studies (68.4%) validated an intensity measure outcome such as energy expenditure, but only 15.9% of studies validated biological state outcomes, while 15.8% of studies validated posture/activity type outcomes. We identified six wearables that had been used to validate outcomes from two different dimensions and only two wearables (ie, ActiGraph GT1M and ActiGraph GT3X+) that validated outcomes from all three dimensions. The percentage of studies meeting a given quality criterion ranged from 44.7% to 92.1%. Only 18 studies were classified as 'low risk' or 'some concerns'. Summary Validation studies on biological state and posture/activity outcomes are rare in children and adolescents. Most studies did not meet published quality principles. Standardised protocols embedded in a validation framework are needed. PROSPERO registration number CRD42021230894

Assessment of 24-hour physical behaviour in children and adolescents via wearables: a systematic review of free-living validation studies

Objectives: Studies that assess all three dimensions of the integrative 24-hour physical behaviour (PB) construct, namely, intensity, posture/activity type and biological state, are on the rise. However, reviews on validation studies that cover intensity, posture/activity type and biological state assessed via wearables are missing. Design: Systematic review. The risk of bias was evaluated by using the QUADAS-2 tool with nine signalling questions separated into four domains (ie, patient selection/study design, index measure, criterion measure, flow and time). Data sources: Peer-reviewed validation studies from electronic databases as well as backward and forward citation searches (1970–July 2021). Eligibility criteria for selecting studies: Wearable validation studies with children and adolescents (age <18 years). Required indicators: (1) study protocol must include real-life conditions; (2) validated device outcome must belong to one dimension of the 24-hour PB construct; (3) the study protocol must include a criterion measure; (4) study results must be published in peer-reviewed English language journals. Results: Out of 13 285 unique search results, 76 articles with 51 different wearables were included and reviewed. Most studies (68.4%) validated an intensity measure outcome such as energy expenditure, but only 15.9% of studies validated biological state outcomes, while 15.8% of studies validated posture/activity type outcomes. We identified six wearables that had been used to validate outcomes from two different dimensions and only two wearables (ie, ActiGraph GT1M and ActiGraph GT3X+) that validated outcomes from all three dimensions. The percentage of studies meeting a given quality criterion ranged from 44.7% to 92.1%. Only 18 studies were classified as ‘low risk’ or ‘some concerns’. Summary: Validation studies on biological state and posture/activity outcomes are rare in children and adolescents. Most studies did not meet published quality principles. Standardised protocols embedded in a validation framework are needed