864 research outputs found
Properly efficient and efficient solutions for vector maximization problems in euclidean space
AbstractRecently Benson proposed a definition for extending Geoffrion's concept of proper efficiency to the vector maximization problem in which the domination cone K is any nontrivial, closed convex cone. We give an equivalent definition of his notion of proper efficiency. Our definition, by means of perturbation of the cone K, seems to offer another justification of Benson's choice above Borwein's extension of Geoffrion's concept. Our result enables one to prove some other theorems concerning properly efficient and efficient points. Among these is a connectedness result
From simple to complicated:Noncausal bounded input, bounded output stability in linear discrete time models in the deterministic and stochastic cases
We consider the question of bounded input, bounded output stability for time-invariant linear systems with a finite dimensional state space and with time axis , i.e., all the integers. Our approach also includes the stochastic ARMA models. We do not assume that the inputs are necessarily nonanticipating, and in this respect our results differ from most existing ones. Similar results have been given by Hannan and Deistler and by Brockwell and Davis. Our approach is polynomial-algebra-oriented, and does not use strictly rational functions
Weakly Equivalent Arrays
The (extensional) theory of arrays is widely used to model systems. Hence,
efficient decision procedures are needed to model check such systems. Current
decision procedures for the theory of arrays saturate the read-over-write and
extensionality axioms originally proposed by McCarthy. Various filters are used
to limit the number of axiom instantiations while preserving completeness. We
present an algorithm that lazily instantiates lemmas based on weak equivalence
classes. These lemmas are easier to interpolate as they only contain existing
terms. We formally define weak equivalence and show correctness of the
resulting decision procedure
Biodegradable hollow fibres for the controlled release of drugs
Biodegradable hollow fibres of poly-l-lactic acid (PLLA) filled with a suspension of the contraceptive hormone levonorgestrel in castor oil were implanted subcutaneously in rats to study the rate of drug release, rate of biodegradation and tissue reaction caused by the implant. The in vivo drug release was compared with the release in vitro using different release media. Fibres, disinfected with alcohol showed a zero-order release, both in vitro and in vivo, for over 6 months. Fibres, either γ-sterilized or disinfected with alcohol were harvested at time intervals ranging from 1 d to 6 months after implantation. Molecular weights of PLLA, tensile strengths, and remaining amounts of drug were determined as a function of time.\ud
\ud
The tissue reaction can be described as a very moderate foreign body reaction with the initial presence of macrophages, which are gradually replaced by fibroblasts which form a collagen capsule. Molecular weight determinations of PLLA showed a decrease from an initial Mw of 1.59x10 5 to 5.5 × 10 4 in 4 months (after alcohol sterilization). A gradual decrease in fibre strength with time was observed which did not significantly impair the release rate of levonorgestrel
Nonperturbative study of generalized ladder graphs in a \phi^2\chi theory
The Feynman-Schwinger representation is used to construct scalar-scalar bound
states for the set of all ladder and crossed-ladder graphs in a \phi^2\chi
theory in (3+1) dimensions. The results are compared to those of the usual
Bethe-Salpeter equation in the ladder approximation and of several
quasi-potential equations. Particularly for large couplings, the ladder
predictions are seen to underestimate the binding energy significantly as
compared to the generalized ladder case, whereas the solutions of the
quasi-potential equations provide a better correspondence. Results for the
calculated bound state wave functions are also presented.Comment: 5 pages revtex, 3 Postscripts figures, uses epsf.sty, accepted for
publication in Physical Review Letter
Relativistic bound-state equations in three dimensions
Firstly, a systematic procedure is derived for obtaining three-dimensional
bound-state equations from four-dimensional ones. Unlike ``quasi-potential
approaches'' this procedure does not involve the use of delta-function
constraints on the relative four-momentum. In the absence of negative-energy
states, the kernels of the three-dimensional equations derived by this
technique may be represented as sums of time-ordered perturbation theory
diagrams. Consequently, such equations have two major advantages over
quasi-potential equations: they may easily be written down in any Lorentz
frame, and they include the meson-retardation effects present in the original
four-dimensional equation. Secondly, a simple four-dimensional equation with
the correct one-body limit is obtained by a reorganization of the generalized
ladder Bethe-Salpeter kernel. Thirdly, our approach to deriving
three-dimensional equations is applied to this four-dimensional equation, thus
yielding a retarded interaction for use in the three-dimensional bound-state
equation of Wallace and Mandelzweig. The resulting three-dimensional equation
has the correct one-body limit and may be systematically improved upon. The
quality of the three-dimensional equation, and our general technique for
deriving such equations, is then tested by calculating bound-state properties
in a scalar field theory using six different bound-state equations. It is found
that equations obtained using the method espoused here approximate the wave
functions obtained from their parent four-dimensional equations significantly
better than the corresponding quasi-potential equations do.Comment: 28 pages, RevTeX, 6 figures attached as postscript files. Accepted
for publication in Phys. Rev. C. Minor changes from original version do not
affect argument or conclusion
Study of relativistic bound states for scalar theories in Bethe-Salpeter and Dyson-Schwinger formalism
The Bethe-Salpeter equation for Wick-Cutkosky like models is solved in
dressed ladder approximation. The bare vertex truncation of the Dyson-Schwinger
equations for propagators is combined with the dressed ladder Bethe-Salpeter
equation for the scalar S-wave bound state amplitudes. With the help of
spectral representation the results are obtained directly in Minkowski space.
We give a new analytic formula for the resulting equation simplifying the
numerical treatment. The bare ladder approximation of Bethe-Salpeter equation
is compared with the one with dressed ladder. The elastic electromagnetic form
factors is calculated within the relativistic impulse approximation.Comment: 30 pages, 10 figures, accepted for publication in Phys. Rev.
Ancestral Admixture Is the Main Determinant of Global Biodiversity in Fission Yeast
Mutation and recombination are key evolutionary processes governing phenotypic variation and reproductive isolation. We here demonstrate that biodiversity within all globally known strains of Schizosaccharomyces pombe arose through admixture between two divergent ancestral lineages. Initial hybridization was inferred to have occurred ∼20-60 sexual outcrossing generations ago consistent with recent, human-induced migration at the onset of intensified transcontinental trade. Species-wide heritable phenotypic variation was explained near-exclusively by strain-specific arrangements of alternating ancestry components with evidence for transgressive segregation. Reproductive compatibility between strains was likewise predicted by the degree of shared ancestry. To assess the genetic determinants of ancestry block distribution across the genome, we characterized the type, frequency, and position of structural genomic variation using nanopore and single-molecule real-time sequencing. Despite being associated with double-strand break initiation points, over 800 segregating structural variants exerted overall little influence on the introgression landscape or on reproductive compatibility between strains. In contrast, we found strong ancestry disequilibrium consistent with negative epistatic selection shaping genomic ancestry combinations during the course of hybridization. This study provides a detailed, experimentally tractable example that genomes of natural populations are mosaics reflecting different evolutionary histories. Exploiting genome-wide heterogeneity in the history of ancestral recombination and lineage-specific mutations sheds new light on the population history of S. pombe and highlights the importance of hybridization as a creative force in generating biodiversity
Feynman-Schwinger representation approach to nonperturbative physics
The Feynman-Schwinger representation provides a convenient framework for the
cal culation of nonperturbative propagators. In this paper we first investigate
an analytically solvable case, namely the scalar QED in 0+1 dimension. With
this toy model we illustrate how the formalism works. The analytic result for
the self energy is compared with the perturbative result. Next, using a
interaction, we discuss the regularization of various divergences
encountered in this formalism. The ultraviolet divergence, which is common in
standard perturbative field theory applications, is removed by using a
Pauli-Villars regularization. We show that the divergence associated with large
values of Feynman-Schwinger parameter is spurious and it can be avoided by
using an imaginary Feynman parameter .Comment: 26 pages, 9 figures, minor correctio
- …