Sobre los orígenes de la idea de "comunidad política" en la Corona Castellano-leonesa

Durante el siglo XIII, tuvo lugar en Castilla una intensa actividad de impulso del pensamiento político, siendo uno sus efectos principales, la creación de criterios de definición de lo que puede interpretarse como idea de comunidad política. A partir de criterios de índole teológica, jurídica, territorial, histórica o lingüística, se estableció una amplia base de fundamentación para esta idea de comunidad política. Sin embargo, la distinta interpretación del concepto de comunidad política en contextos de confrontación, será un rasgo muy característico de los sucesivos conflictos políticos. Resultado de esta evolución ideológica fue la justificación de distintos modelos políticos. En consecuencia, el concepto de comunidad política planteado en el siglo XIII aportó criterios esenciales para entender los conflictos políticos de los siglos XIV y XV

Insights into the structural evolution of the pre-Variscan rocks of the Eastern Pyrenees from La Molina quartz veins; constraints on chlorite and fluid inclusion thermometry

Quartz veins hosted in the infra and overlying series to the (Sardic) Upper Ordovician Unconformity provide new insights into the structural and thermal evolution of the pre-Variscan rocks of the Eastern Pyrenees. In the La Molina area (Canigó massif), two generations of metric quartz veins (V1 and V2) are distinguished by their distribution patterns and their relationships to the deformational macro, meso, and microstructures. P-T formation conditions are obtained by combining chlorite geothermometry and fluid inclusion microthermometry data. Discrepancy on formation temperature for chlorites located at different positions within the veins are discussed, concluding that veins grew in a low fluid/rock ratio regime. V1 veins can be related to the Late Ordovician syn-sedimentary faulting episode as revealed by their distribution patterns, formation mechanisms, and fluid-rock interactions. We propose an Alpine age for the V2 veins, based on their structure and the emplacement conditions of 318 ± 12°C and 2.4 ± 0.2kbar, with an estimated geothermal gradient of 34°C∙km-1 and a burial depth of ca. 9km. Results obtained here are compared with other quartz veins spread throughout the Paleozoic basement of the Eastern Pyrenees

One-parameter nonrelativistic supersymmetry for microtubules

The one-parameter nonrelativistic supersymmetry of Mielnik [J. Math. Phys. 25, 3387 (1984)] is applied to the simple supersymmetric model of Caticha [Phys. Rev. A 51, 4264 (1995)] in the form used by Rosu [Phys. Rev. E 55, 2038 (1997)] for microtubules. By this means, we introduce Montroll double-well potentials with singularities that move along the positive or negative traveling direction depending on the sign of the free parameter of Mielnik's method. Possible interpretations of the singularity are either microtubule associated proteins (motors) or structural discontinuities in the arrangement of the tubulin moleculesComment: 6 pages, 5 figures, minor change

Contribución al conocimiento del género Anthyllis L. (Fabaceae) en la Península Ibérica A. plumosa sp. nov

Se realiza un estudio morfológico, palinológico y cariológico de tres especies del género Anthyllis (sect. Oreanthyllis), describiéndose una nueva especie, A. plumosa E. Domínguez procedente de las arenas dolomíticas de la Sierra de Almijara (Málaga).In this paper a morphological, palynological and caryological study of three species of Anthyllis (sect. Oreanthyllis) is included. As a consecuence a new species A. plumosa E. Domínguez from the dolomitics sands of Sierra de Almijara (Málaga) is described

Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands

Sigma (σ) receptors, initially described as a subtype of opioid receptors, are now considered unique receptors. Pharmacological studies have distinguished two types of σ receptors, termed σ1 and σ2. Of these two subtypes, the σ1 receptor has been cloned in humans and rodents, and its amino acid sequence shows no homology with other mammalian proteins. Several psychoactive drugs show high to moderate affinity for σ1 receptors, including the antipsychotic haloperidol, the antidepressant drugs fluvoxamine and sertraline, and the psychostimulants cocaine and methamphetamine; in addition, the anticonvulsant drug phenytoin allosterically modulates σ1 receptors. Certain neurosteroids are known to interact with σ1 receptors, and have been proposed to be their endogenous ligands. These receptors are located in the plasma membrane and in subcellular membranes, particularly in the endoplasmic reticulum, where they play a modulatory role in intracellular Ca2+ signaling. Sigma1 receptors also play a modulatory role in the activity of some ion channels and in several neurotransmitter systems, mainly in glutamatergic neurotransmission. In accordance with their widespread modulatory role, σ1 receptor ligands have been proposed to be useful in several therapeutic fields such as amnesic and cognitive deficits, depression and anxiety, schizophrenia, analgesia, and against some effects of drugs of abuse (such as cocaine and methamphetamine). In this review we provide an overview of the present knowledge of σ1 receptors, focussing on σ1 ligand neuropharmacology and the role of σ1 receptors in behavioral animal studies, which have contributed greatly to the potential therapeutic applications of σ1 ligands

Reuniones Internacionales auspiciadas por INIA/AECID en el marco del XX Curso Internacional sobre Enfermedades Infectocontagiosas, Emergentes y Transfronterizas en Animales

Infectious diseases are a threat to animal health and food safety in countries where they are present, and a challenge for all those involved in their containment, control and eradication. In the 20th International Course on Infectious, Emerging and Transboundary Animal Diseases held in Madrid from 2 to 30 November 2011, the objectives outlined were concerned with the analysis of those items of most interest and relevance to the topic from different points of view: etiological, pathogenic and pathological, diagnostic, preventive and epidemiological. In addition, the participants were trained in different laboratory methodologies supporting the diagnostic and epidemiological analysis of the diseases under study. The course was sponsored by the Spanish Agency of International Cooperation forDevelopment (AECID) and the National Research Institute for Agricultural and Food Technology (INIA). Experiencesexchanged included the management of disasters of this kind in the European context, taking into account the regulations described by international agencies. Lectures were held in seven blocks: Biosafety, Epidemiology, Immunology, Pathology, Diagnosis, Prophylaxis and Preventive Medicine. Practical classes, as well as visits to breeding centers, animal slaughterhouses and research laboratories with high biosafety level were also included. Specialists were interviewed about the use of marker vaccines and the control and progressive eradication of diseases, as well as the need to extend appropriate diagnostic methods, depending on the geographical areas.There was a high attendance of specialists and workers of the official veterinary services and scientific institutionsfrom different countries of South America, Central America, the Caribbean and Spain, in addition to interested students and guests from institutions of excellence in the subject. It can be concluded that the course met with the objectives and contributed to the training of specialists involved in issues related to the diagnosis and control measures of important emerging infectious diseases affecting various animal species

Co-simulation platform for geometric design, trajectory control and guidance of racing drones

[EN] The design of racing drones brings quite a thrilling challenge from a flight dynamics point of view. This work aims to offer a single-based simulation platform combining its geometric design, trajectory control, and guidance of racing drones. Also, it is reckoned from a pilot¿s view in a classic FPV competition. Hence, it is an active platform for studying racing drones¿ design founded on dynamics, with fifteen different drone models. It is one of the few existing platforms that combine all aspects of racing drones in a single simulation environment. Also, it is open access via Matlab Central - File Exchange.This work was partially supported by proyect PID2020-119468RA-I00 funded by MCIN/AEI/10.13039/501100011033.Castiblanco Quintero, J.; Garcia-Nieto, S.; Simarro Fernández, R.; Salcedo-Romero-De-Ávila, J. (2022). Co-simulation platform for geometric design, trajectory control and guidance of racing drones. International Journal of Micro Air Vehicles. 14:1-20. https://doi.org/10.1177/175682932211437851201

Hard thermal loops and the entropy of supersymmetric Yang-Mills theories

We apply the previously proposed scheme of approximately self-consistent hard-thermal-loop resummations in the entropy of high-temperature QCD to N=4 supersymmetric Yang-Mills (SYM) theories and compare with a (uniquely determined) R[4,4] Pad\'e approximant that interpolates accurately between the known perturbative result and the next-to-leading order strong-coupling result obtained from AdS/CFT correspondence. We find good agreement up to couplings where the entropy has dropped to about 85% of the Stefan-Boltzmann value. This is precisely the regime which in purely gluonic QCD corresponds to temperatures above 2.5 times the deconfinement temperature and for which this method of hard-thermal-loop resummation has given similar good agreement with lattice QCD results. This suggests that in this regime the entropy of both QCD and N=4 SYM is dominated by effectively weakly coupled hard-thermal-loop quasiparticle degrees of freedom. In N=4 SYM, strong-coupling contributions to the thermodynamic potential take over when the entropy drops below 85% of the Stefan-Boltzmann value.Comment: 14 pages, 2 figures, JHEP3. v2: revised and expanded, with unchanged HTL results but corrected NLO strong-coupling result from AdS/CFT (which is incorrectly reproduced in almost all previous papers comparing weak and strong coupling results of N=4 SYM) and novel (unique) Pade approximant interpolating between weak and strong coupling result

IFCP Riemann solver: Application to tsunami modelling using GPUs

In this work, we present a simplified two-layer model of Savage-Hutter type to simulate tsunamis generated by landslides (see (Fern´andez et al. 2008)). A layer composed of fluidized granular material is assumed to flow within an upper layer composed of an inviscid fluid (e.g. water). The sediment layer ismodelled by a Savage-Hutter type model where buoyancy effects have been considered. The system is discretized using IFCP finite volume scheme. The first order IFCP scheme was introduced in (Fern´andez et al. 2011) and it is constructed by using a suitable decomposition of a Roe matrix by means of a parabolic viscosity matrix, that captures information of the intermediate fields (Intermediate Field Capturing Parabola). Its extension to high order and two-dimensional domains is straightforward. To conclude, some numerical examples are presente