17 research outputs found
Scholarly Impact of Law School Faculties in 2018: Updating the Leiter Score Ranking for the Top Third
Belgium, Canada and Switzerland: Are There Differences in the Contributions of Selected Variables on Self-Reported Property-Related and Violent Delinquency?
Three countries with different sociodemographic characteristics and different school and criminal justice systems are compared using data from Belgium, Switzerland, and Canada with respect to juvenile delinquency as measured by the International Self-Reported Delinquency questionnaire (ISRD-2). Following a brief presentation of descriptive statistics of the different samples, multivariate analyses including basic variables such as gender, age, family composition, immigrant status, school attachment, victimisation, and family and peer relationships make up the core of this study. The contributions of these selected variables are then compared between the participating countries. Between these three countries we find similarities and differences in explaining self-reported property-related and violent delinquency. In the final part of the article, the implications of these findings are discusse
Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTICâHF: baseline characteristics and comparison with contemporary clinical trials
Aims:
The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTICâHF) trial. Here we describe the baseline characteristics of participants in GALACTICâHF and how these compare with other contemporary trials.
Methods and Results:
Adults with established HFrEF, New York Heart Association functional class (NYHA)ââ„âII, EF â€35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokineticâguided dosing: 25, 37.5 or 50âmg bid). 8256 patients [male (79%), nonâwhite (22%), mean age 65âyears] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NTâproBNP 1971âpg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTICâHF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressureâ<â100âmmHg (n = 1127), estimated glomerular filtration rate <â30âmL/min/1.73 m2 (n = 528), and treated with sacubitrilâvalsartan at baseline (n = 1594).
Conclusions:
GALACTICâHF enrolled a wellâtreated, highârisk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation
Team approach to data synthesis: the playbook for creating a centralized, dynamic, and sustainable ANPP database, A
The SGS-LTER research site was established in 1980 by researchers at Colorado State University as part of a network of long-term research sites within the US LTER Network, supported by the National Science Foundation. Scientists within the Natural Resource Ecology Lab, Department of Forest and Rangeland Stewardship, Department of Soil and Crop Sciences, and Biology Department at CSU, California State Fullerton, USDA Agricultural Research Service, University of Northern Colorado, and the University of Wyoming, among others, have contributed to our understanding of the structure and functions of the shortgrass steppe and other diverse ecosystems across the network while maintaining a common mission and sharing expertise, data and infrastructure.Includes bibliographical references.The Grasslands Data Integration (GDI) project has brought together ecologists, information managers and computer scientists to address the interdisciplinary challenges of integrating ANPP data from multiple sources. In this poster we present 1) the necessity to coordinate expertise and information to integrate ANPP data and metadata from five national and international grassland LTER sites, 2) the data model we designed to archive and serve the data, and 3) analysis planned for the future. This collaboration is an example of how professionals with inter-related work experience build a community of experts and a successful data product for the LTER (Baker and Millerand 2007).NSF Canopy Database Project (NSF Grants: DBI-0417311, DBI-0319309), JRN-LTER (NSF Grant: DEB-0080412), KNZ-LTER (NSF Grant: DEB-0218210), SEV-LTER (NSF Grant: DEB-0080529), and SGS-LTER (NSF Grant: DEB-0217631)
Scholarly Impact of Law School Faculties in 2018: Updating the Leiter Score Ranking for the Top Third
Belgium, Canada and Switzerland : Are There Differences in the Contributions of Selected Variables on Self-Reported Property-Related and Violent Delinquency ?
Three countries with different sociodemographic characteristics and different school and criminal justice systems are compared using data from Belgium, Switzerland, and Canada with respect to juvenile delinquency as measured by the International Self-Reported Delinquency questionnaire (ISRD-2). Following a brief presentation of descriptive statistics of the different samples, multivariate analyses including basic variables such as gender, age, family composition, immigrant status, school attachment, victimisation, and family and peer relationships make up the core of this study. The contributions of these selected variables are then compared between the participating countries. Between these three countries we find similarities and differences in explaining self-reported property-related and violent delinquency. In the final part of the article, the implications of these findings are discussed