Applications of high pressure differential scanning calorimetry to aviation fuel thermal stability research

High pressure differential scanning calorimetry (DSC) was studied as an alternate method for performing high temperature fuel thermal stability research. The DSC was used to measure the heat of reaction versus temperature of a fuel sample heated at a programmed rate in an oxygen pressurized cell. Pure hydrocarbons and model fuels were studied using typical DSC operating conditions of 600 psig of oxygen and a temperature range from ambient to 500 C. The DSC oxidation onset temperature was determined and was used to rate the fuels on thermal stability. Kinetic rate constants were determined for the global initial oxidation reaction. Fuel deposit formation is measured, and the high temperature volatility of some tetralin deposits is studied by thermogravimetric analysis. Gas chromatography and mass spectrometry are used to study the chemical composition of some DSC stressed fuels

Constraining the Λ\LambdaCDM and Galileon models with recent cosmological data

The Galileon theory belongs to the class of modified gravity models that can explain the late-time accelerated expansion of the Universe. In previous works, cosmological constraints on the Galileon model were derived, both in the uncoupled case and with a disformal coupling of the Galileon field to matter. There, we showed that these models agree with the most recent cosmological data. In this work, we used updated cosmological data sets to derive new constraints on Galileon models, including the case of a constant conformal Galileon coupling to matter. We also explored the tracker solution of the uncoupled Galileon model. After updating our data sets, especially with the latest \textit{Planck} data and BAO measurements, we fitted the cosmological parameters of the $\Lambda$CDM and Galileon models. The same analysis framework as in our previous papers was used to derive cosmological constraints, using precise measurements of cosmological distances and of the cosmic structure growth rate. We showed that all tested Galileon models are as compatible with cosmological data as the $\Lambda$CDM model. This means that present cosmological data are not accurate enough to distinguish clearly between both theories. Among the different Galileon models, we found that a conformal coupling is not favoured, contrary to the disformal coupling which is preferred at the $2.3\sigma$ level over the uncoupled case. The tracker solution of the uncoupled Galileon model is also highly disfavoured due to large tensions with supernovae and \textit{Planck}+BAO data. However, outside of the tracker solution, the general uncoupled Galileon model, as well as the general disformally coupled Galileon model, remain the most promising Galileon scenarios to confront with future cosmological data. Finally, we also discuss constraints coming from Lunar Laser Ranging experiment and gravitational wave speed of propagation.Comment: 22 pages, 17 figures, published version in A&

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Mitochondrial decline in ageing robs cells of ATP. However, animal studies show that long wavelength exposure (650-900 nm) over weeks partially restores ATP and improves function. The likely mechanism is via long wavelengths reducing nanoscopic interfacial water viscosity around ATP rota pumps, improving their efficiency. Recently, repeated 670 nm exposures have been used on the aged human retina, which has high-energy demands and significant mitochondrial and functional decline, to improve vision. We show here that single 3 min 670 nm exposures, at much lower energies than previously used, are sufficient to significantly improve for 1 week cone mediated colour contrast thresholds (detection) in ageing populations (37-70 years) to levels associated with younger subjects. But light needs to be delivered at specific times. In environments with artificial lighting humans are rarely dark-adapted, hence cone function becomes critical. This intervention, demonstrated to improve aged mitochondrial function can be applied to enhance colour vision in old age

First experimental constraints on the disformally coupled Galileon model

The Galileon model is a modified gravity model that can explain the late-time accelerated expansion of the Universe. In a previous work, we derived experimental constraints on the Galileon model with no explicit coupling to matter and showed that this model agrees with the most recent cosmological data. In the context of braneworld constructions or massive gravity, the Galileon model exhibits a disformal coupling to matter, which we study in this paper. After comparing our constraints on the uncoupled model with recent studies, we extend the analysis framework to the disformally coupled Galileon model and derive the first experimental constraints on that coupling, using precise measurements of cosmological distances and the growth rate of cosmic structures. In the uncoupled case, with updated data, we still observe a low tension between the constraints set by growth data and those from distances. In the disformally coupled Galileon model, we obtain better agreement with data and favour a non-zero disformal coupling to matter at the $2.5\sigma$ level. This gives an interesting hint of the possible braneworld origin of Galileon theory.Comment: 9 pages, 6 figures, updated versio

Improved planning abilities in binge eating.

OBJECTIVE: The role of planning in binge eating episodes is unknown. We investigated the characteristics of planning associated with food cues in binging patients. We studied planning based on backward reasoning, reasoning that determines a sequence of actions back to front from the final outcome. METHOD: A cross-sectional study was conducted with 20 healthy participants, 20 bulimia nervosa (BN), 22 restrictive (ANR) and 23 binging anorexia nervosa (ANB), without any concomitant impulsive disorder. In neutral/relaxing, binge food and stressful conditions, backward reasoning was assessed with the Race game, promotion of delayed large rewards with an intertemporal discounting task, attention with the Simon task, and repeating a dominant behavior with the Go/No-go task. RESULTS: BN and to a lower extent ANB patients succeeded more at the Race game in food than in neutral condition. This difference discriminated binging from non-binging participants. Backward reasoning in the food condition was associated with lower approach behavior toward food in BN patients, and higher food avoidance in ANB patients. Enhanced backward reasoning in the food condition related to preferences for delayed large rewards in BN patients. In BN and ANB patients the enhanced success rate at the Race game in the food condition was associated with higher attention paid to binge food. CONCLUSION: These findings introduce a novel process underlying binges: planning based on backward reasoning is associated with binges. It likely aims to reduce craving for binge foods and extend binge refractory period in BN patients, and avoid binging in ANB patients. Shifts between these goals might explain shifts between eating disorder subtypes

Variational solution of the Gross-Neveu model; 2, finite-N and renormalization

We show how to perform systematically improvable variational calculations in the O(2N) Gross-Neveu model for generic N, in such a way that all infinities usually plaguing such calculations are accounted for in a way compatible with the renormalization group. The final point is a general framework for the calculation of non-perturbative quantities like condensates, masses, etc..., in an asymptotically free field theory. For the Gross-Neveu model, the numerical results obtained from a "two-loop" variational calculation are in very good agreement with exact quantities down to low values of N

Supersymmetric quantum mechanics living on topologically nontrivial Riemann surfaces

Supersymmetric quantum mechanics is constructed in a new non-Hermitian representation. Firstly, the map between the partner operators $H^{(\pm)}$ is chosen antilinear. Secondly, both these components of a super-Hamiltonian ${\cal H}$ are defined along certain topologically nontrivial complex curves $r^{(\pm)}(x)$ which spread over several Riemann sheets of the wave function. The non-uniqueness of our choice of the map ${\cal T}$ between "tobogganic" partner curves $r^{(+)}(x)$ and $r^{(-)}(x)$ is emphasized.Comment: 14p

Survival of near-critical branching Brownian motion

Consider a system of particles performing branching Brownian motion with negative drift $\mu = \sqrt{2 - \epsilon}$ and killed upon hitting zero. Initially there is one particle at $x>0$. Kesten showed that the process survives with positive probability if and only if $\epsilon>0$. Here we are interested in the asymptotics as \eps\to 0 of the survival probability $Q_\mu(x)$. It is proved that if $L= \pi/\sqrt{\epsilon}$ then for all $x \in \R$, $\lim_{\epsilon \to 0} Q_\mu(L+x) = \theta(x) \in (0,1)$ exists and is a travelling wave solution of the Fisher-KPP equation. Furthermore, we obtain sharp asymptotics of the survival probability when $x<L$ and $L-x \to \infty$. The proofs rely on probabilistic methods developed by the authors in a previous work. This completes earlier work by Harris, Harris and Kyprianou and confirms predictions made by Derrida and Simon, which were obtained using nonrigorous PDE methods

Prospective Study of the Phenotypic and Mutational Spectrum of Ocular Albinism and Oculocutaneous Albinism

Albinism encompasses a group of hereditary disorders characterized by reduced or absent ocular pigment and variable skin and/or hair involvement, with syndromic forms such as Hermansky-Pudlak syndrome and Chédiak-Higashi syndrome. Autosomal recessive oculocutaneous albinism (OCA) is phenotypically and genetically heterogenous (associated with seven genes). X-linked ocular albinism (OA) is associated with only one gene, GPR143. We report the clinical and genetic outcomes of 44 patients, from 40 unrelated families of diverse ethnicities, with query albinism presenting to the ocular genetics service at Moorfields Eye Hospital NHS Foundation Trust between November 2017 and October 2019. Thirty-six were children (≤ 16 years) with a median age of 31 months (range 2-186), and eight adults with a median age of 33 years (range 17-39); 52.3% (n = 23) were male. Genetic testing using whole genome sequencing (WGS, n = 9) or a targeted gene panel (n = 31) gave an overall diagnostic rate of 42.5% (44.4% (4/9) with WGS and 41.9% (13/31) with panel testing). Seventeen families had confirmed mutations in TYR (n = 9), OCA2, (n = 4), HPS1 (n = 1), HPS3 (n = 1), HPS6 (n = 1), and GPR143 (n = 1). Molecular diagnosis of albinism remains challenging due to factors such as missing heritability. Differential diagnoses must include SLC38A8-associated foveal hypoplasia and syndromic forms of albinism