796 research outputs found
The travels of Joseph Beal Steere in Brazil, Peru and Ecuador (1870-1873)
Joseph Beal Steere (1842-1940) was sent by the University of Michigan in a trip around the world, from 1870 (September) to 1875, to collect materials in all departments of natural and human sciences for the University's Museum. He went from New York to Brazil (São Luís, Maranhão), proceeding up the Amazon, and spent about eighteen months on that river and some of its tributaries. Arrived at the head of navigation of the Amazon, at the mouth of the Río Santiago (Peru), he floated back two hundred miles on a raft, to reach the mouth of the Huallaga. He ascended this river to Yurimaguas, going thence across the Andes. He made part of the journey on foot and horseback; on the way he spent some time in the old cities of Moyobamba, Chachapoyas and Cajamarca. He struck the sea-coast at a town called Huanchaco, near the city of Trujillo; thence he went to Lima; and from there to Guayaquil; and thence, overland, to Quito, continually adding to his store of specimens. While at Quito, he ascended the volcano Pichincha and went to the bottom of the crater. He returned from Quito to Lima and made an excursion along the coast of Peru, collecting old Peruvian pottery from graves, etc. From Lima he went to Cerro de Pasco mining regions, making collections of minerals. Returning to Lima, he crossed the Pacific in a ship bound for Macao, China. From Macao he jouneyed successively to Hong Kong and Canton; from Canton to the Island of Formosa, where he spent six or eight months making journeys among the savages of the interior. From Formosa he went, via Hong Kong and Canton, to the Philippine Islands, and spent ten months there; he visited several places never before visited by naturalists, and found forty new species of birds. From the Philippines he went to Singapore, thence to Malacca, and made a trip through the Dutch Moluccas, touching at several places in the islands of Java, Macassar, Amboina and Ternate. From these islands he returned to Singapore, and from there, via Suez Canal and the Mediterranean, to Marseilles, stopping at Naples. He went through France by rail and via London and Liverpool went home, after an absence of little more than three years. Periodically he wrote letters telling of his adventures and impressions, with notes on the regions visited, to a weekly magazine edited in Ann Arbor, the Peninsular Courier and Family Visitant, where they were published. The 62 letters written by Steere in South America (Brazil, Peru and Ecuador) are here transcribed and commented.Joseph Beal Steere (1842-1940) foi enviado pela Universidade de Michigan numa viagem ao redor do mundo, de 1870 (setembro) até 1875, para coletar espécimes em todas as áreas das ciências naturais e humanas para o Museu da Universidade. De Nova Iorque embarcou para o Brasil (São Luís, Maranhão), subindo depois o rio Amazonas e permaneceu 18 meses nesse rio e alguns de seus afluentes. Chegado ao término da navegação do Amazonas, na boca do rio Santiago (Peru), desceu numa balsa, por duzentas milhas, para chegar à boca do Huallaga. Subiu este rio até Yurimaguas, de onde atravessou os Andes. Parte da viagem foi feita a pé ou a cavalo, e no caminho passou algum tempo nas antigas cidades de Moyobamba, Chachapoyas e Cajamarca. Atingiu a costa em uma cidade chamada Huanchaco, perto da cidade de Trujillo, e daí foi para Lima, depois para Guayaquil, e, por terra, a Quito, sempre coletando. Em Quito subiu o vulcão Pichincha e foi até o fundo de sua cratera. De volta a Quito e Lima fez uma excursão pela costa do Peru, coletando antiga cerâmica peruana em túmulos etc. De Lima foi à região mineira de Cerro de Pasco, para coletar minerais. Finalmente, partiu da capital peruana e cruzou o Pacífico num navio que se dirigia a Macau, na China. De Macau viajou sucessivamente a Hong Kong e Cantão, de Cantão à ilha de Formosa, onde permaneceu de seis a oito meses fazendo viagens entre os selvagens do interior. De Formosa, via Hong Kong e Cantão, foi para as Filipinas, onde passou dez meses, visitando muitos lugares nunca antes visitados por naturalistas e encontrou quarenta espécies novas de aves. Das Filipinas foi a Cingapura, daí para Malaca, e viajou pelas Molucas Holandesas, parando em lugares como Java, Macassar, Amboina e Ternate. Dessas ilhas regressou a Cingapura e dali, via o Canal de Suez e o Mediterrâneo, foi a Marselha, com uma escala em Nápoles. Cruzando a França por trem, chegou a Londres e de Liverpool voltou para os Estados Unidos, depois de uma ausência de pouco mais de três anos. Periodicamente escrevia cartas narrando suas aventuras e impressões, com notas sobre as regiões visitadas, ao Peninsular Courier and Family Visitant, uma revista semanal editada em Ann Arbor, onde eram publicadas. As 62 cartas escritas por Steere na América do Sul (Brasil, Peru e Equador) são transcritas abaixo, com comentários
Aquilegia, Vol. 18 No. 3, May-June 1994: Newsletter of the Colorado Native Plant Society
https://epublications.regis.edu/aquilegia/1071/thumbnail.jp
Does the process map influence the outcome of quality improvement work? A comparison of a sequential flow diagram and a hierarchical task analysis diagram
Background: Many quality and safety improvement methods in healthcare rely on a complete and accurate map of the process. Process mapping in healthcare is often achieved using a sequential flow diagram, but there is little guidance available in the literature about the most effective type of process map to use. Moreover there is evidence that the organisation of information in an external representation affects reasoning and decision making. This exploratory study examined whether the type of process map - sequential or hierarchical - affects healthcare practitioners' judgments.Methods: A sequential and a hierarchical process map of a community-based anti coagulation clinic were produced based on data obtained from interviews, talk-throughs, attendance at a training session and examination of protocols and policies. Clinic practitioners were asked to specify the parts of the process that they judged to contain quality and safety concerns. The process maps were then shown to them in counter-balanced order and they were asked to circle on the diagrams the parts of the process where they had the greatest quality and safety concerns. A structured interview was then conducted, in which they were asked about various aspects of the diagrams.Results: Quality and safety concerns cited by practitioners differed depending on whether they were or were not looking at a process map, and whether they were looking at a sequential diagram or a hierarchical diagram. More concerns were identified using the hierarchical diagram compared with the sequential diagram and more concerns were identified in relation to clinical work than administrative work. Participants' preference for the sequential or hierarchical diagram depended on the context in which they would be using it. The difficulties of determining the boundaries for the analysis and the granularity required were highlighted.Conclusions: The results indicated that the layout of a process map does influence perceptions of quality and safety problems in a process. In quality improvement work it is important to carefully consider the type of process map to be used and to consider using more than one map to ensure that different aspects of the process are captured
The Ursinus Weekly, November 20, 1950
14th Messiah will be given December 7th • Fifteen seniors honored with listing in annual publication of Who\u27s Who • WSSF drive kindles much campus activity • Thespians to give psychological mystery, Angel Street, December first and second • May Day petition deadline is Tuesday • Bloodmobile coming to Collegeville December 7 • Ruby group pictures to be taken after Thanksgiving • MSGA to seek vote on dorm amendment • Jones reads poems of Eliot to Tuesday night audience • Gillespie\u27s orchestra to furnish music for December 8 Sunnybrook senior ball • Editorial: Spirit of Thanksgiving; Dorm government: Its meaning; Counsel for the councils • Frosberg has three-fold job • Herbsleb discusses international law before local IRC • Freshmen women elect Jen Price chairman of decoration committee • Library work in progress • Undergrads invited to join competition in contract bridge • Dart tourney • Como concert postponed • Chess Club wins • Herbsleb addresses pre-legal society • Belles edged 2-1 by Owlette squad • Chestnut Hill falls to Snell\u27s Belles 5-0 • Jayvee coeds triumph over Chestnut Hill 2-0 • Diplomats win 2-0 over Bear booters • Dragons 5-1 victors over soccer squad • Plan student bowling • Grizzlies tie Susquehanna in grid season finale, 6-6https://digitalcommons.ursinus.edu/weekly/1553/thumbnail.jp
Developing a pressure ulcer risk factor minimum data set and risk assessment framework
AIM: To agree a draft pressure ulcer risk factor Minimum Data Set to underpin the development of a new evidenced-based Risk Assessment Framework.BACKGROUND: A recent systematic review identified the need for a pressure ulcer risk factor Minimum Data Set and development and validation of an evidenced-based pressure ulcer Risk Assessment Framework. This was undertaken through the Pressure UlceR Programme Of reSEarch (RP-PG-0407-10056), funded by the National Institute for Health Research and incorporates five phases. This article reports phase two, a consensus study.DESIGN: Consensus study.METHOD: A modified nominal group technique based on the Research and Development/University of California at Los Angeles appropriateness method. This incorporated an expert group, review of the evidence and the views of a Patient and Public Involvement service user group. Data were collected December 2010-December 2011.FINDINGS: The risk factors and assessment items of the Minimum Data Set (including immobility, pressure ulcer and skin status, perfusion, diabetes, skin moisture, sensory perception and nutrition) were agreed. In addition, a draft Risk Assessment Framework incorporating all Minimum Data Set items was developed, comprising a two stage assessment process (screening and detailed full assessment) and decision pathways.CONCLUSION: The draft Risk Assessment Framework will undergo further design and pre-testing with clinical nurses to assess and improve its usability. It will then be evaluated in clinical practice to assess its validity and reliability. The Minimum Data Set could be used in future for large scale risk factor studies informing refinement of the Risk Assessment Framework
The development of sentence-interpretation strategies in monolingual German-learning children with and without specific language impairment
Previous research on sentence comprehension conducted with German-learning children has concentrated on the role of case marking and word order in typically developing children. This paper compares, the performance of German-learning children with language impairment (age 4-6 years) and without language impairment (aged 2-6, 8-9 years) in two experiments that systematically vary the cues animacy, case marking; word-order, and subject-verb agreement. The two experiments differ with regard to the choice of case marking: in the first it is distinct but in the second it is neutralized. The theoretical framework is the competition model developed by Bates and Mac Whinney and their collaborators, a variant of the parallel distributed processing models. It is hypothesized that children of either population first appreciate the cue animacy that can be processed locally, that is, "on the spot," before they turn to more distributed cues leading ultimately up to subject-verb agreement, which presupposes the comparison of various constituents before an interpretation can be established. Thus agreement is more "costly" in processing than animacy or the (more) local cue initial NP. In experiment I with unambiguous case markers it is shown that the typically developing children proceed from animacy to the nominative (predominantly in coalition with the initial NP) to agreement, while in the second experiment with ambiguous case markers these children turn from animacy to the initial NP and then to agreement. The impaired children also progress from local to distributed cues. Yet, in contrast to the control group, they do not acknowledge the nominative in coalition with the initial NP in the first experiment but only in support of agreement. However, although they do not seem to appreciate distinct case markers to any large extent in the first experiment, they are irritated if such distinctions are lacking: in experiment II all impaired children turn to. animacy (some in coalition with the initial NP and/or particular word orders). In the discussion, the relationship between short-term memory and processing as well as the relationship between production and comprehension of case markers and agreement are addressed. Further research is needed to explore in more detail "cue costs" in sentence comprehension
Evaluation of the impact of a school gardening intervention on children's fruit and vegetable intake: a randomised controlled trial.
Background: Current academic literature suggests that school gardening programmes can provide an interactive environment with the potential to change children’s fruit and vegetable intake. This is the first cluster randomised controlled trial (RCT) designed to evaluate whether a school gardening programme can have an effect on children’s fruit and vegetable intake.
Methods: The trial included children from 23 schools; these schools were randomised into two groups, one to receive the Royal Horticultural Society (RHS)-led intervention and the other to receive the less involved Teacher-led intervention. A 24-hour food diary (CADET) was used to collect baseline and follow-up dietary intake 18 months apart. Questionnaires were also administered to evaluate the intervention implementation.
Results: A total of 641 children completed the trial with a mean age of 8.1 years (95% CI: 8.0, 8.4). The unadjusted results from multilevel regression analysis revealed that for combined daily fruit and vegetable intake the Teacher-led group had a higher daily mean change of 8 g (95% CI: −19, 36) compared to the RHS-led group -32 g (95% CI: −60, −3). However, after adjusting for possible confounders this difference was not significant (intervention effect: −40 g, 95% CI: −88, 1; p = 0.06). The adjusted analysis of process measures identified that if schools improved their gardening score by 3 levels (a measure of school gardening involvement - the scale has 6 levels from 0 ‘no garden’ to 5 ‘community involvement’), irrespective of group allocation, children had, on average, a daily increase of 81 g of fruit and vegetable intake (95% CI: 0, 163; p = 0.05) compared to schools that had no change in gardening score.
Conclusions: This study is the first cluster randomised controlled trial designed to evaluate a school gardening intervention. The results have found very little evidence to support the claims that school gardening alone can improve children’s daily fruit and vegetable intake. However, when a gardening intervention is implemented at a high level within the school it may improve children’s daily fruit and vegetable intake by a portion. Improving children’s fruit and vegetable intake remains a challenging task
Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate-cancer patients
Disseminated epithelial cells can be isolated from the bone marrow of a far greater fraction
of prostate-cancer patients than the fraction of patients who progress to metastatic disease.
To provide a better understanding of these cells, we have characterized their genomic alterations.
We first present an array comparative genomic hybridization method capable of detecting
genomic changes in the small number of disseminated cells (10-20) that can typically be obtained
from bone-marrow aspirates of prostate-cancer patients. We show multiple regions of
copy-number change, including alterations common in prostate cancer, such as 8p loss, 8q gain,
and gain encompassing the androgen-receptor gene on Xq, in the disseminated cell pools from
11 metastatic patients. We found fewer and less striking genomic alterations in the 48 pools of
disseminated cells from patients with organ-confined disease. However, we identify changes
shared by these samples with their corresponding primary tumors and prostate-cancer alterations
reported in the literature, evidence that these cells, like those in advanced disease, are
disseminated tumor cells (DTCs). We also demonstrate that DTCs from patients with advanced
and localized disease share several abnormalities, including losses containing cell-adhesion
genes and alterations reported to associate with progressive disease. These shared alterations
might confer the capability to disseminate or establish secondary disease. Overall, the spectrum
of genomic deviations is evidence for metastatic capacity in advanced-disease DTCs and variation
in that capacity in DTCs from localized disease. Our analysis lays the foundation for elucidation
of the relationship between DTC genomic alterations and progressive prostate cancer
Study protocol: can a school gardening intervention improve children's diets?
BACKGROUND: The current academic literature suggests there is a potential for using gardening as a tool to improve children's fruit and vegetable intake. This study is two parallel randomised controlled trials (RCT) devised to evaluate the school gardening programme of the Royal Horticultural Society (RHS) Campaign for School Gardening, to determine if it has an effect on children's fruit and vegetable intake. METHOD/DESIGN: Trial One will consist of 26 schools; these schools will be randomised into two groups, one to receive the intensive intervention as "Partner Schools" and the other to receive the less intensive intervention as "Associate Schools". Trial Two will consist of 32 schools; these schools will be randomised into either the less intensive intervention "Associate Schools" or a comparison group with delayed intervention. Baseline data collection will be collected using a 24-hour food diary (CADET) to collect data on dietary intake and a questionnaire exploring children's knowledge and attitudes towards fruit and vegetables. A process measures questionnaire will be used to assess each school's gardening activities. DISCUSSION: The results from these trials will provide information on the impact of the RHS Campaign for School Gardening on children's fruit and vegetable intake. The evaluation will provide valuable information for designing future research in primary school children's diets and school based interventions. TRIAL REGISTRATION: ISRCTN11396528
Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis
The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis. We aimed to explore the longitudinal development of the gut microbiome in preterm twins to determine how shared environmental and genetic factors may influence temporal changes and compared this to the expressed breast milk (EBM) microbiome. Stool samples (n = 173) from 27 infants (12 twin pairs and 1 triplet set) and EBM (n = 18) from 4 mothers were collected longitudinally. All samples underwent PCR-DGGE (denaturing gradient gel electrophoresis) analysis and a selected subset underwent 454 pyrosequencing. Stool and EBM shared a core microbiome dominated by Enterobacteriaceae, Enterococcaceae, and Staphylococcaceae. The gut microbiome showed greater similarity between siblings compared to unrelated individuals. Pyrosequencing revealed a reduction in diversity and increasing dominance of Escherichia sp. preceding NEC that was not observed in the healthy twin. Antibiotic treatment had a substantial effect on the gut microbiome, reducing Escherichia sp. and increasing other Enterobacteriaceae.
This study demonstrates related preterm twins share similar gut microbiome development, even within the complex environment of neonatal intensive care. This is likely a result of shared genetic and immunomodulatory factors as well as exposure to the same maternal microbiome during birth, skin contact and exposure to EBM. Environmental factors including antibiotic exposure and feeding are additional significant determinants of community structure, regardless of host genetics
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