OpenLab ESEV: novas aventuras no desenvolvimento de software

OpenLab ESEV is the Free Software project of the School of Education - Polytechnic Institute of Viseu (ESEV). The project aims to establish a platform to aggregate activities that foster the use of Free/Libre and Open Source Software (F/LOSS), Free Culture and more flexible licenses for creative and educational purposes in the ESEV's domains of activity (education, arts, media). OpenLab exists since 2009. It emerged in an environment characterized by the lack of knowledge of the existing Libre alternatives and by work habits exclusively built around proprietary software. Today, OpenLab activities are implemented within four key areas of action: dissemination, training, support and production. This paper presents two of the most important ongoing projects: Ottographer and StudiozCollabPress. StudiozCollabPress is a customized version of a popular WordPress plugin for project management that was developed to support short movie projects management. We'll present its main features and results from real-case scenarios of use, specifically, finished and ongoing 3D animation students' projects. Ottographer is a webcam time-lapse tool for operating systems based on Debian GNU/Linux. Besides the main features, we'll present some examples and suggestions for educational settings as well as for creative and educational purposes. Both projects are distributed as F/LOSS, meaning that they can be used, studied, and modified without restrictions, as well as copied and redistributed in modified or unmodified form. These projects might help us launch a new trend at our school community that we highly antecipate: the development and sharing of our own tools

Experimental study of charged particles movement in electric and magnetic fields: velocity selector

Neste trabalho é apresentado um experimento incluído no contexto de experimentos longos adotado nas disciplinas experimentais de eletricidade, magnetismo e óptica, e consiste na caracterização de um seletor de velocidades que funciona com campos elétricos e magnéticos cruzados. Utiliza-se um tubo de raios catódicos para gerar um feixe de elétrons. As placas de deflexão vertical do tubo geram o campo elétrico e um par de bobinas, com os eixos perpendiculares ao eixo do tubo, gera o campo magnético. São realizados estudos de trajetória dos elétrons com auxílio de um programa de simulação de elétrons.In this work we present an experiment included in the context of long-duration experiments adopted in the electricity, magnetism and optics experimental disciplines, which consists in characterizing a velocity selector working with crossed electric and magnetic fields. We make use of a cathode ray tube to generate an electron beam. The tube's vertical deflection plates generate the electric field and a pair of coils with their axis perpendicular to the tube, generate the magnetic field. We perform investigations of the electron trajectory with the support of a simulation code

Therapy influence on the plastic processes of nervous system: theory and research (part I)

El sistema nervioso (SN) está destinado al control de todos los órganos y sistemas. Está continuamente en actividad con funciones extremamente importantes como las funciones de adaptar el organismo a las modificaciones externas, manteniendo su ambiente interno constante a través de sistemas como el vegetativo y el hormonal. En ningún otro lugar las conexiones entre las células son tan críticas respecto al adecuado funcionamiento de los órganos, como en el SN. Curiosamente no hace muchos años a los estudiantes se les enseñaba que las células nerviosas humanas eran tan especializadas que era imposible su reparación. Actualmente se conoce que el SN puede rehabilitarse a si mismo, regularmente. Es por lo que uno de los objetivos de las neurociencias es aprender cómo estimular las células nerviosas adecuadamente, para que ellas tengan una capacidad plástica más exuberante, haciendo o rehaciendo conexiones funcionales. Siempre que se habla sobre el SN, debemos tener en mente que es un todo, único, indivisible, altamente integrado y dividido apenas con finalidades didácticas. Así, aún elaborando una división anatómica y funcional del SN, él se desarrolla, organiza, procesa, aprende y actúa como un todo. Para que este SN tenga condiciones para organizarse y más adelante controlar adecuadamente sus innumerables funciones, se necesita de un programa genético y de factores epigenéticos adecuados (factores ambientales). El programa genético ofrece posibilidades importantes para un desarrollo normal o no del SN. Determinadas mutaciones neurogénicas culminan en diferentes niveles de malformaciones neuro-anatomofuncionales. En segundo lugar los factores epigenéticos no alteran el programa genético, pero influyen en la expresión de este programa. Como ejemplo clásico, podemos citar al síndrome de la privación, donde los niños hospitalizados durante un largo período, o los niños que se desarrollan en orfanatos tienen en general un retraso en la adquisición de una serie de funciones sensitivomotoras, como por ejemplo el retraso en la adquisición de la lenguaje articulado, disociación entre las cinturas escapular y pélvica, marcha, etc. De esta forma, a través de los dos ítems anteriormente citados, tenemos la biografía del individuo, la cual es la base para las diferencias individuales.Terapia y Rehabilitació

Electrooxidation and determination of dopamine using a Nafion®-cobalt hexacyanoferrate film modified electrode

The electrocatalysis of dopamine has been studied using a cobalt hexacyanoferrate film (CoHCFe)-modified glassy carbon electrode. Using a rotating disk CoHCFe-modified electrode, the reaction rate constant for dopamine was found to be 3.5 × 105 cm3 mol-1 s-1 at a concentration of 5.0 × 10-5 mol L-1. When a Nafion® film is applied to the CoHCFe-modified electrode surface a high selectivity for the determination of dopamine over ascorbic acid was obtained. The analytical curve for dopamine presented linear dependence over the concentration range from 1.2 × 10-5 to 5.0 × 10-4 mol L-1 with a slope of 23.5 mA mol-1 L and a linear correlation coefficient of 0.999. The detection limit of this method was 8.9 × 10-6 mol L-1 and the relative standard deviation for five measurements of 2.5 × 10-4 mol L-1 dopamine was 0.58%

Study of low-pass and high-pass RC filters by means of a circuit for signal superposition

Apresentamos nesse trabalho, um experimento realizado nos Laboratórios didáticos do Instituto de Física da USP, relacionado ao estudo do funcionamento de filtros RC para baixas e altas freqüências. Para tal, foi especialmente projetado um circuito que efetua a superposição de um sinal gerado internamente, a uma onda senoidal externa. Várias situações experimentais podem ser geradas, por meio da variação da freqüência, tanto do sinal interno quanto da onda senoidal externa. Um estudo das componentes de freqüência de Fourier é também realizado para se estabelecer os parâmetros de funcionamento dos filtros. O funcionamento dos circuitos como integradores e diferenciadores também é explorado. Os estudantes são, portanto, levados a compreender a eficácia desses filtros mais simples, dependendo das freqüências dos sinais de entrada e correspondentes componentes de Fourier, e das freqüências de corte estabelecidas.In this work we present an experiment performed in the undergraduate laboratories at the University of São Paulo Physics Institute. It is related to the study of low-pass and high-pass RC filters. For this purpose, we designed and constructed a circuit for the superposition of an internally generated signal and an external sinusoidal signal. An investigation of the Fourier frequency components is also performed in order to establish working parameters for the RC filters. The operation of the circuits as integrators and differentiators is also explored. The students are therefore led to understand how efficient these circuits can be depending on the frequency and Fourier components of the entrance signals, as well as the cutoff frequencies previously defined

Adapting Real Quantifier Elimination Methods for Conflict Set Computation

The satisfiability problem in real closed fields is decidable. In the context of satisfiability modulo theories, the problem restricted to conjunctive sets of literals, that is, sets of polynomial constraints, is of particular importance. One of the central problems is the computation of good explanations of the unsatisfiability of such sets, i.e.\ obtaining a small subset of the input constraints whose conjunction is already unsatisfiable. We adapt two commonly used real quantifier elimination methods, cylindrical algebraic decomposition and virtual substitution, to provide such conflict sets and demonstrate the performance of our method in practice

Ratio of proportions and the use of the delta method for confidence interval estimation in logistic regression

OBJECTIVE: To present an application of logistic regression modelling to estimate ratios of proportions, such as prevalence ratio or relative risk, and the Delta Method to estimate confidence intervals. METHOD: The Delta Method was used because it is appropriate for the estimation of variance of non-linear functions of random variables. The method is based on Taylor's series expansion and provides a good approximation of variance estimates. A computer program, utilizing the matrix module of SAS, was developed to compute the variance estimates. A practical demonstration is presented with data from a cross-sectional study carried out on a sample of 611 women, to test the hypothesis that the lack of housework sharing is associated with high scores of psychological symptoms as measured by a validated questionnaire. RESULTS: Crude and adjusted prevalence ratio estimated by logistic regression were similar to those estimated by tabular analysis. Also, ranges of the confidence intervals of the prevalence ratio according to the Delta Method were nearly equal to those obtained by the Mantel-Haenszel approach. CONCLUSIONS: The results give support to the use of the Delta Method for the estimation of confidence intervals for ratios of proportions. The method should be seen as an alternative for situations in which the need to control a large number of potential confounders limits the use of stratified analysis.OBJETIVO: Apresentar uma aplicação da regressão logística para estimar razões de prevalência ou risco relativo, e o uso do método delta para a estimativa de intervalos de confiança. MÉTODOS: Utilizou-se o método delta, visto que esta técnica é adequada para estimar variâncias de funções não lineares de variáveis aleatórias, do tipo razão de proporções. O método baseia-se na expansão da função em série de Taylor, provendo uma aproximação para o cálculo das variâncias. Para estimar as razões de proporções e as respectivas variâncias, que permitem a estimação dos intervalos de confiança, desenvolveu-se programa utilizando-se o módulo matricial do SAS. A aplicação prática do modelo proposto é feita utilizando-se dados de um estudo transversal com uma amostra de 611 mulheres, para testar a hipótese de que a falta de compartilhamento do trabalho doméstico associa-se com altos escores de sintomas psicológicos medidos através de um questionário validado. As razões de prevalência calculadas através da regressão logística, e os intervalos de confiança estimados pelo método delta foram comparadas com os resultados obtidos pela técnica de Mantel-Haenszel. RESULTADOS: As estimativas pontuais das razões de prevalência brutas, cruas ou ajustadas, obtidas através da regressão logística, foram semelhantes às encontradas na análise tabular. Também os limites dos intervalos de confianças para as razões de prevalência através do método delta foram praticamente iguais em relação aos encontrados através da técnica de Mantel-Haenszel. CONCLUSÕES: Os resultados apóiam o uso do método delta para estimar intervalos de confiança para razões de proporção. Esse método deve ser visto como uma alternativa para situações em que o efeito em estudo (variável dependente) não é raro, situação onde a "odds ratio" se afasta das medidas epidemiológicas caracterizadas como razão de proporções

Identification by MALDI-TOF MS of Sporothrix brasiliensis isolated from a subconjunctival infiltrative lesion in an immunocompetent patient

Sporotrichosis is a globally distributed subcutaneous fungal infection caused by dimorphic fungi belonging to the Sporothrix species complex that affects the skin of limbs predominantly, but not exclusively. A rare case of ocular sporotrichosis in an immunocompetent Brazilian patient from the countryside of Rio de Janeiro State is reported. A 68-year-old woman presented with a subconjunctival infiltrative lesion in the right eye with pre-auricular lymphadenopathy of onset 4 months ago that evolved to suppurative nodular lesions on the eyelids. Conjunctival secretion was evaluated by histopathological examination and inoculated on Sabouraud Dextrose Agar (SDA). Histopathology showed oval bodies within giant cells and other mononucleated histiocytes. Fungus grown on SDA was identified as Sporothrix sp. by morphological observations. The isolated strain was finally identified by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) associated with an in-house database enriched with reference Sporothrix complex spectra. The strain presented a MALDI spectrum with the ion peaks of the molecular mass profile of S. brasiliensis. The patient was adequately treated with amphotericin B subsequently replaced by itraconazole. Due to scars left by the suppurative process, the patient presented poor final visual acuity. The present work presents an overview of ocular sporotrichosis and discusses the diagnostic difficulty that can lead to visual sequelae in these cases.Financial support for this work by Fundação de Amparo à Pesquisa do Rio de Janeiro [FAPERJ] (Grants: INST E-26/010.001784/2016; JCNE E-26/203.301/2017), by Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq] (Grant Proc. 409227/2016-1). This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES). MALDI-TOF MS analyses were partially developed using equipment funded by CONICYT/Chile through the project Fondequip EQM160054 2016. The Universidad de La Frontera (Temuco, Chile) partially funded this work through the Project DIUFRO PIA19-0001. Furthermore, this study was also supported by FCT under the scope of the strategic funding of UID/BIO/04469/2019 unit and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norte.info:eu-repo/semantics/publishedVersio