Idiopathic Thrombocytopenic Purpura (ITP): A Case Report

Idiopathic thrombocytopenic purpura (ITP) is an anomalous decrease in the number of platelets with obscure etiologic causes. Clinical signs primarily include muco-cutaneous i.e. Petechia, purpura, ecchymosis. The most important aspects of management in this disease, is to anticipate, and control bleeding hence preventing any life threatening consequences. Transfusion of platelets, steroid therapy, Anti-D immunoglobulin are the main stay of treatment. Thrombopoietin receptor agonists and splenectomy may be necessary in some severe cases. We report a case of a young girl with ITP, identified at our unit. She was admitted to the hospital for observation and was successfully treated with steroids therapy

Micropropagation And Antimicrobial Activity Of Callicarpa Macrophylla (Priyangu) Against Medically Important Pathogens

Callicarpa macrophylla (Priyangu) a medicinally important plant, represents a class of herbal drug with very strong conceptual and traditional base. In present study extract of leaf, stem showed less antimicrobial activity than seed. They showed antimicrobial activity against three bacterial strains Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas and three fungal Strains Aspergillus fumigatous, Rhizopus oryzae and Aspergillus awamori. Maximum activity was observed in ethanol extract of leaf and stem, Methanol extracts of seed. Phytochemical analysis of the plant extract revealed the presence of phenol, reducing sugar, coumarin and saponins.  Micropropogation of C.macrophylla was done using stem as a explant material on MS and Woody media. Which revealed that woody media containing BAP (6-amino benzyl purine) NAA(α-napthaleneacetic acid) gave maximum proliferation  response in comparison to MS media. Plant extract (leave, stem and seed) have provide protection against RBC haemolysis and protein denaturation may act as anti-arthritic agent. We propose antiarthritic and antimicrobial activity of C.macrophylla

Hydrolytic cleavage of paraoxon and parathion by oximate and functionalized oximate ions: A comparative study

560-565<span style="font-size:11.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-bidi-font-family:="" mangal;letter-spacing:-.1pt;mso-ansi-language:en-gb;mso-fareast-language:en-us;="" mso-bidi-language:hi"="" lang="EN-GB">Bimolecular reactions of O,O-diethyl-O-p-nitrophenylphosphate (paraoxon) and O,O-diethyl-O-p-nitrophenyl phosphorothioate (parathion) with oximate (pyridinealdoxime 2-PyOx- and 4-PyOx-) and its functionalized oximate, 4-(hydroxyimino)methyl)-1-alkylpyridinium bromide ions (alkyl = C10H21 (4-C10PyOx-); alkyl = C12H25 (4-C12PyOx-)) have been investigated in aqueous and cationic micellar media of cetylpyridinium bromide, cetyltrimethyl-ammonium bromide and cetyltetradecyltrimethylammonium bromide at pH 9.5 and 27 oC. Under the micellized condition, a 1.2×103 fold and 9.0×106 fold rate enhancement over the aqueous reaction of paraoxon (ko = 7.5×10-8 s-1) and parathion (ko = 9.5×10-11) is observed.</span