Toward the Ab-initio Description of Medium Mass Nuclei

As ab-initio calculations of atomic nuclei enter the A=40-100 mass range, a great challenge is how to approach the vast majority of open-shell (degenerate) isotopes. We add realistic three-nucleon interactions to the state of the art many-body Green's function theory of closed-shells, and find that physics of neutron driplines is reproduced with very good quality. Further, we introduce the Gorkov formalism to extend ab-initio theory to semi-magic, fully open-shell, isotopes. Proof-of-principle calculations for Ca-44 and Ni-74 confirm that this approach is indeed feasible. Combining these two advances (open-shells and three-nucleon interactions) requires longer, technical, work but it is otherwise within reach.Comment: Contribution to Summary Report of EURISOL Topical and Town Meetings, 15-19 October 2012; missing affiliations added and corrected errors in Tab

Structure of A=10-13 nuclei with two- plus three-nucleon interactions from chiral effective field theory

Properties of finite nuclei are evaluated with two-nucleon (NN) and three-nucleon (NNN) interactions derived within chiral effective field theory (EFT). The nuclear Hamiltonian is fixed by properties of the A=2 system, except for two low-energy constants (LECs) that parameterize the short range NNN interaction. We constrain those two LECs by a fit to the A=3 system binding energy and investigate sensitivity of 4He, 6Li, 10,11B and 12,13C properties to the variation of the constrained LECs. We identify a preferred choice that gives globally the best description. We demonstrate that the NNN interaction terms significantly improve the binding energies and spectra of mid-p-shell nuclei not just with the preferred choice of the LECs but even within a wide range of the constrained LECs. At the same time, we find that a very high quality description of these nuclei requires further improvements to the chiral Hamiltonian.Comment: 4 pages, 4 figure

Exact calculation of three-body contact interaction to second order

For a system of fermions with a three-body contact interaction the second-order contributions to the energy per particle $\bar E(k_f)$ are calculated exactly. The three-particle scattering amplitude in the medium is derived in closed analytical form from the corresponding two-loop rescattering diagram. We compare the (genuine) second-order three-body contribution to $\bar E(k_f)\sim k_f^{10}$ with the second-order term due to the density-dependent effective two-body interaction, and find that the latter term dominates. The results of the present study are of interest for nuclear many-body calculations where chiral three-nucleon forces are treated beyond leading order via a density-dependent effective two-body interaction.Comment: 9 pages, 6 figures, to be published in European Journal

A mixed-mode shell-model theory for nuclear structure studies

We introduce a shell-model theory that combines traditional spherical states, which yield a diagonal representation of the usual single-particle interaction, with collective configurations that track deformations, and test the validity of this mixed-mode, oblique basis shell-model scheme on $^{24}$Mg. The correct binding energy (within 2% of the full-space result) as well as low-energy configurations that have greater than 90% overlap with full-space results are obtained in a space that spans less than 10% of the full space. The results suggest that a mixed-mode shell-model theory may be useful in situations where competing degrees of freedom dominate the dynamics and full-space calculations are not feasible.Comment: 20 pages, 8 figures, revtex 12p

Boson-conserving one-nucleon transfer operator in the interacting boson model

The boson-conserving one-nucleon transfer operator in the interacting boson model (IBA) is reanalyzed. Extra terms are added to the usual form used for that operator. These new terms change generalized seniority by one unit, as the ones considered up to now. The results obtained using the new form for the transfer operator are compared with those obtained with the traditional form in a simple case involving the pseudo-spin Bose-Fermi symmetry $U^{B}(6) \otimes U^F(12)$ in its $U^{BF}(5) \otimes U^F(2)$ limit. Sizeable differences are found. These results are of relevance in the study of transfer reactions to check nuclear supersymmetry and in the description of (\beta)-decay within IBA.Comment: 13 pages, 1 table, 0 figures. To be published in Phys. Rev.

Topological Analysis of Metabolic Networks Integrating Co-Segregating Transcriptomes and Metabolomes in Type 2 Diabetic Rat Congenic Series

Background: The genetic regulation of metabolic phenotypes (i.e., metabotypes) in type 2 diabetes mellitus is caused by complex organ-specific cellular mechanisms contributing to impaired insulin secretion and insulin resistance. Methods: We used systematic metabotyping by 1H NMR spectroscopy and genome-wide gene expression in white adipose tissue to map molecular phenotypes to genomic blocks associated with obesity and insulin secretion in a series of rat congenic strains derived from spontaneously diabetic Goto-Kakizaki (GK) and normoglycemic Brown-Norway (BN) rats. We implemented a network biology strategy approach to visualise shortest paths between metabolites and genes significantly associated with each genomic block. Results: Despite strong genomic similarities (95-99%) among congenics, each strain exhibited specific patterns of gene expression and metabotypes, reflecting metabolic consequences of series of linked genetic polymorphisms in the congenic intervals. We subsequently used the congenic panel to map quantitative trait loci underlying specific metabotypes (mQTL) and genome-wide expression traits (eQTL). Variation in key metabolites like glucose, succinate, lactate or 3-hydroxybutyrate, and second messenger precursors like inositol was associated with several independent genomic intervals, indicating functional redundancy in these regions. To navigate through the complexity of these association networks we mapped candidate genes and metabolites onto metabolic pathways and implemented a shortest path strategy to highlight potential mechanistic links between metabolites and transcripts at colocalized mQTLs and eQTLs. Minimizing shortest path length drove prioritization of biological validations by gene silencing. Conclusions: These results underline the importance of network-based integration of multilevel systems genetics datasets to improve understanding of the genetic architecture of metabotype and transcriptomic regulations and to characterize novel functional roles for genes determining tissue-specific metabolism

The Long Journey from Ab Initio Calculations to Density Functional Theory for Nuclear Large Amplitude Collective Motion

At present there are two vastly different ab initio approaches to the description of the the many-body dynamics: the Density Functional Theory (DFT) and the functional integral (path integral) approaches. On one hand, if implemented exactly, the DFT approach can allow in principle the exact evaluation of arbitrary one-body observable. However, when applied to Large Amplitude Collective Motion (LACM) this approach needs to be extended in order to accommodate the phenomenon of surface-hoping, when adiabaticity is strongly violated and the description of a system using a single (generalized) Slater determinant is not valid anymore. The functional integral approach on the other hand does not appear to have such restrictions, but its implementation does not appear to be straightforward endeavor. However, within a functional integral approach one seems to be able to evaluate in principle any kind of observables, such as the fragment mass and energy distributions in nuclear fission. These two radically approaches can likely be brought brought together by formulating a stochastic time-dependent DFT approach to many-body dynamics.Comment: 9 page

Axially symmetric Hartree-Fock-Bogoliubov Calculations for Nuclei Near the Drip-Lines

Nuclei far from stability are studied by solving the Hartree-Fock-Bogoliubov (HFB) equations, which describe the self-consistent mean field theory with pairing interaction. Calculations for even-even nuclei are carried out on two-dimensional axially symmetric lattice, in coordinate space. The quasiparticle continuum wavefunctions are considered for energies up to 60 MeV. Nuclei near the drip lines have a strong coupling between weakly bound states and the particle continuum. This method gives a proper description of the ground state properties of such nuclei. High accuracy is achieved by representing the operators and wavefunctions using the technique of basis-splines. The detailed representation of the HFB equations in cylindrical coordinates is discussed. Calculations of observables for nuclei near the neutron drip line are presented to demonstrate the reliability of the method.Comment: 13 pages, 4 figures. Submitted to Physical Review C on 05/08/02. Revised on Dec/0

Proton radiotherapy at PTC Czech in Prague

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