Estilos de aprendizaje, estrategias de aprendizaje y hábitos de estudio de estudiantes universitarios estudio descriptivo a realizarse con estudiantes inscritos en la Facultad de Ciencias Sociales de la Universidad Francisco Gavidia en las Carreras de Licenciatura en Psicología y Licenciatura en Ciencias de la Educación a nivel del segundo año en el ciclo II-2012

El interés por conocer los estilos de aprendizaje, estrategias de aprendizaje y hábitos de estudio de los estudiantes viene desde hace mucho tiempo; no obstante en la actualidad esta cuestión adquiere una mayor relevancia, en gran medida por los avances de la educación, así como las altas tasas de fracaso escolar. De hecho, diversas investigaciones se orientan a conocer con profundidad los procesos de aprendizaje y a valorar en qué grado influyen los estilos de aprendizaje, las estrategias de aprendizaje y los hábitos de estudio en el rendimiento escolar. Se tiene la creencia que el estudiante cuando ingresa a la Universidad ya posee estos procesos de aprendizaje lo suficientemente aceptables; sin embargo, la experiencia muestra que un número significativo de estudiantes de enseñanza superior obtienen deficientes resultados, porque no todos hacen frente con éxito a los nuevos desafíos que la Universidad plantea: aumento de exigencia, necesidad creciente de organización de trabajo académico, mayor dedicación al estudio, autonomía, etc

¿Qué evalúan los instrumentos de evaluación?. Valoraciones de estudiantes

The instruments used for information gathering provide the information to assess whether students have achieved the competences set out in the training plan. Therefore, knowing how they understand and describe the capabilities and skills they are demonstrating is useful information to be considered at times of change and curriculum restructuring. In this paper we describe the results of study in which students describe what is involved in each of the assessment techniques they have undergone during their undergraduate studies and what skills were used in each case. With this information, we have tried to organise the types of tools to collect information with skills developed from the perceptions of students, presenting a continuum of cognitive abilities.Los instrumentos empleados para la recogida de información aportan la información para evaluar si se han logrado las competencias previstas en un plan formativo. Por ello, conocer cómo entienden y describen los estudiantes las capacidades y destrezas que están demostrando en ellos, es una información a tener en cuenta en momentos de cambio y reestructuraciones de los planes de estudio. En este artículo mostramos los resultados obtenidos en una investigación, en la que los estudiantes describen qué implica cada una de las técnicas de evaluación que han realizado a lo largo de sus estudios de licenciatura y qué destrezas debían emplear en cada una de ellas. Con la información recogida, hemos intentado organizar las tipologías de instrumentos de recogida de información con las capacidades desarrolladas desde las percepciones de los estudiantes, presentando un continuo de habilidades cognitivas

Bienestar laboral de los docentes y administrativos de la Universidad de la costa C.U.C en el 2013

Especialización en Estudios PedagógicosThe main purpose of this study was to describe the occupational well-being of the full time teachers and administrative personnel from the University “Universidadde la Costa – C.U.C.” The specific objectives were to determinate the psychosocial well-being factors and identify the collateral effects. This project is based on a quantitative investigation. The population was integrated and constituted by a representative sample of 254 people between full time teachers, scholars and administrative personnel of the University “Universidad de la Costa – C.U.C.” In order to accomplish the objectives for this investigation, the Occupational Well-being Questionare by Joseph Blanch, Miguel Shagun and Genis Cervantes, was applied; this is a theoretical model of occupational well-being which includes a descriptive dimension of the Psychosocial Well-being (integrated by affections, skills and expectations) and the other category of colateral effects(somatization, burnout and alientation) to employees in different departments and faculties. The question about satisfaction and work-quality is emphasized by the results with the highest score by the scholars, in the second place the administrative personnel, which manifested having experimented satisfaction and work-quality in the Institution, but suggesting actions of improvement; the last group was the full time teachers who generally scored lower than the other two groups, maybe because they manifested some indicators of favorability based on their work conditions and how they feel about their job. This can infer the necessity to revise the upcoming actions, in order to increase the levels of acceptance and compromise with the system developed by the University. It is concluded that the well-being is an important aspect to improve the quality of the employees working life and to make possible having a better course of action developed by the UniversityLa presente investigación tuvo como objetivo general describir el bienestar laboral de los docentes y administrativos de la Universidad de la Costa – C.U.C. Y dentro de los objetivos específicos determinar los factores de bienestar psicosocial e identificar los efectos colaterales. Este trabajo está fundamentado en una investigación de corte cuantitativo. La población estuvo conformada una muestra constituida por 254 sujetos entre docentes y administrativos de la Universidad de la Costa C.U.C. Para el cumplimiento de los objetivos se aplicó el cuestionario de Bienestar Laboral general de Joseph Blanch, Miguel Sahagún y Genís Cervantes, un modelo teórico de bienestar laboral que incluye la descripción de una dimensión de bienestar psicosocial (integrada por afectos, competencias y expectativas) y otra de efectos colaterales (somatización, desgaste y alienación) a cada uno de los funcionarios en las diferentes dependencias y en las facultades. Dentro de los resultados se destaca lo referido al hecho de que las máximas puntuaciones en alto grado corresponden a la valoración emitida por los docentes catedráticos, los administrativos le siguen, puesto que en su mayoría manifiestan haber experimentado satisfacción y calidad laboral en la institución pero con índices de acciones de mejoría, y por último los docentes tiempo completo quienes por lo general puntuaban por debajo de los dos primeros posiblemente manifiesta algunos indicadores de favorabilidad frente a las condiciones y sentires acerca del trabajo que desarrollan, de lo cual se infiere la necesidad de revisar las acciones a proponer para procurar aumentar sus niveles de aceptación y compromiso con los procesos desarrollados en la universidad. Se concluye entonces que el bienestar es un aspecto importante para mejora la calidad de vida laboral de los empleados de la institución y por ende posibilita la mejora de los procesos que desarrollan en la mism

Bienestar laboral de los docentes y administrativos de la Universidad de la Costa C.U.C. en el 2013

Especialización en Estudios PedagógicosThe main purpose of this study was to describe the occupational well-being of the full time teachers and administrative personnel from the University “Universidad de la Costa – C.U.C.” The specific objectives were to determinate the psychosocial well-being factors and identify the collateral effects. This project is based on a quantitative investigation. The population was integrated and constituted by a representative sample of 254 people between full time teachers, scholars and administrative personnel of the University “Universidad de la Costa – C.U.C.” In order to accomplish the objectives for this investigation, the Occupational Wellbeing Questionare by Joseph Blanch, Miguel Shagun and Genis Cervantes, was applied; this is a theoretical model of occupational well-being which includes a descriptive dimension of the Psychosocial Well-being (integrated by affections, skills and expectations) and the other category of colateral effects (somatization, burnout and alientation) to employees in different departments and faculties. The question about satisfaction and work-quality is emphasized by the results with the highest score by the scholars, in the second place the administrative personnel, which manifested having experimented satisfaction and work-quality in the Institution, but suggesting actions of improvement; the last group was the full time teachers who generally scored lower than the other two groups, maybe because they manifested some indicators of favorability based on their work conditions and how they feel about their job. This can infer the necessity to revise the upcoming actions, in order to increase the levels of acceptance and compromise with the system developed by the University. It is concluded that the well-being is an important aspect to improve the quality of the employees working life and to make possible having a better course of action developed by the University.La presente investigación tuvo como objetivo general describir el bienestar laboral de los docentes y administrativos de la Universidad de la Costa – C.U.C. Y dentro de los objetivos específicos determinar los factores de bienestar psicosocial e identificar los efectos colaterales. Este trabajo está fundamentado en una investigación de corte cuantitativo. La población estuvo conformada una muestra constituida por 254 sujetos entre docentes y administrativos de la Universidad de la Costa C.U.C. Para el cumplimiento de los objetivos se aplicó el cuestionario de Bienestar Laboral general de Joseph Blanch, Miguel Sahagún y Genís Cervantes, un modelo teórico de bienestar laboral que incluye la descripción de una dimensión de bienestar psicosocial (integrada por afectos, competencias y expectativas) y otra de efectos colaterales (somatización, desgaste y alienación) a cada uno de los funcionarios en las diferentes dependencias y en las facultades. Dentro de los resultados se destaca lo referido al hecho de que las máximas puntuaciones en alto grado corresponden a la valoración emitida por los docentes catedráticos, los administrativos le siguen, puesto que en su mayoría manifiestan haber experimentado satisfacción y calidad laboral en la institución pero con índices de acciones de mejoría, y por último los docentes tiempo completo quienes por lo general puntuaban por debajo de los dos primeros posiblemente manifiesta algunos indicadores de favorabilidad frente a las condiciones y sentires acerca del trabajo que desarrollan, de lo cual se infiere la necesidad de revisar las acciones a proponer para procurar aumentar sus niveles de aceptación y compromiso con los procesos desarrollados en la universidad. Se concluye entonces que el bienestar es un aspecto importante para mejora la calidad de vida laboral de los empleados de la institución y por ende posibilita la mejora de los procesos que desarrollan en la misma

Nutritional Supplementation to Increase Influenza Vaccine Response in Children Living With HIV: A Pilot Clinical Trial

Final results of this work have been presented at the following meetings: 36rd Annual Meeting of the European Society for Pediatric Infectious Diseases (ESPID 2018), Malmö, Sweden, 28th May-June 2nd, 2018. (Ref. ESP18-0517).Aims: Vaccine response is poor among children living with HIV. The gut microbiota has been identified as a potential target to improve vaccine immunogenicity, but data are scarce in the context of HIV infection. Methods: Pilot, double-blind, randomized placebo-controlled trial in which 24 HIV-infected children were randomized to receive a mixture of symbiotics, omega-3/6 fatty acids, and amino acids or placebo for 4 weeks, each in combination with ART, and were then immunized against influenza. Vaccine response and safety of the nutritional supplementation were the primary outcomes. Results: Eighteen HIV-infected children completed the follow-up period (mean age 11.5 ± 4.14 years, 61% female). The nutritional supplement was safe but did not enhance the response to the influenza vaccine. A 4-fold rise in antibody titers was obtained in only 37.5% of participants in the intervention arm vs. 40% in the placebo. No immunological or inflammatory predictors of vaccine response were identified. Conclusions: In this exploratory study, a 4-week course of symbiotics did not increase influenza vaccine immunogenicity in HIV-infected children. Larger studies are warranted to address the potential of modulating the microbiome in children living with HIV.This work was funded by the Instituto de Salud Carlos III-Fondos FEDER (grant number CB21/17/00025), Acción Estratégica en Salud (PI13/0422, PI17/01283, PI18/00154, and PI18CIII/00009). TS and SS-V have been funded by the Instituto de Salud Carlos III-Fondos FEDER (BA21/00022 and BA21/00017). The funding bodies did not have a role in the design or conduct of the study, the analysis and interpretation of the results, and the writing of the report or the decision to publish. The authors would like to particularly acknowledge all the children and adolescents as well as their families for their participation in this study. They acknowledge the Spanish Pediatric HIV infection Group CORISPE and the Pediatric HIV BioBank integrated in the Spanish AIDS Research Network and collaborating Centers [supported by the Instituto de Salud Carlos III, Spanish Health Ministry (Grant n◦ RD06/0006/0035)] for its collaboration and cession of clinical information and samples used in this work. Nutricion Médica S.L., manufactured and packaged the nutritional product under investigation. Final results of this work have been presented at the following meetings: 36rd Annual Meeting of the European Society for Pediatric Infectious Diseases (ESPID 2018), Malmö, Sweden, 28th May-June 2nd, 2018. (Ref. ESP18-0517).S

Biological and functional analysis of interactions among tetraspanin-associated proteins in human T lymphocites by high-throuchput methods using second generation proteomics techniques

Comunicaciones a congreso

Multiomics Molecular Research into the Recalcitrant and Orphan Quercus ilex Tree Species: Why, What for, and How

The holm oak (Quercus ilex L.) is the dominant tree species of the Mediterranean forest and the Spanish agrosilvopastoral ecosystem, “dehesa.” It has been, since the prehistoric period, an important part of the Iberian population from a social, cultural, and religious point of view, providing an ample variety of goods and services, and forming the basis of the economy in rural areas. Currently, there is renewed interest in its use for dietary diversification and sustainable food production. It is part of cultural richness, both economically (tangible) and environmentally (intangible), and must be preserved for future generations. However, a worrisome degradation of the species and associated ecosystems is occurring, observed in an increase in tree decline and mortality, which requires urgent action. Breeding programs based on the selection of elite genotypes by molecular markers is the only plausible biotechnological approach. To this end, the authors’ group started, in 2004, a research line aimed at characterizing the molecular biology of Q. ilex. It has been a challenging task due to its biological characteristics (long life cycle, allogamous, high phenotypic variability) and recalcitrant nature. The biology of this species has been characterized following the central dogma of molecular biology using the omics cascade. Molecular responses to biotic and abiotic stresses, as well as seed maturation and germination, are the two main objectives of our research. The contributions of the group to the knowledge of the species at the level of DNA-based markers, genomics, epigenomics, transcriptomics, proteomics, and metabolomics are discussed here. Moreover, data are compared with those reported for Quercus spp. All omics data generated, and the genome of Q. ilex available, will be integrated with morphological and physiological data in the systems biology direction. Thus, we will propose possible molecular markers related to resilient and productive genotypes to be used in reforestation programs. In addition, possible markers related to the nutritional value of acorn and derivate products, as well as bioactive compounds (peptides and phenolics) and allergens, will be suggested. Subsequently, the selected molecular markers will be validated by both genome-wide association and functional genomic analyses

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

"This is the peer reviewed version of the following article: Hernández Montoto, Andy, Antoni Llopis-Lorente, Mónica Gorbe, José M. Terrés, Roberto Cao Milán, Borja Díaz de Greñu, María Alfonso, et al. 2019. Janus Gold Nanostars Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery. Chemistry A European Journal 25 (36). Wiley: 8471 78. doi:10.1002/chem.201900750, which has been published in final form at https://doi.org/10.1002/chem.201900750. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."[EN] Janus gold nanostar-mesoporous silica nanoparticle (AuNSt-MSNP) nanodevices able to release an entrapped payload upon irradiation with near infrared (NIR) light were prepared and characterized. The AuNSt surface was functionalized with a thiolated photolabile molecule (5), whereas the mesoporous silica face was loaded with a model drug (doxorubicin) and capped with proton-responsive benzimidazole-beta-cyclodextrin supramolecular gatekeepers (N 1). Upon irradiation with NIR-light, the photolabile compound 5 photodissociated, resulting in the formation of succinic acid, which induced the opening of the gatekeeper and cargo delivery. In the overall mechanism, the gold surface acts as a photochemical transducer capable of transforming the NIR-light input into a chemical messenger (succinic acid) that opens the supramolecular nanovalve. The prepared hybrid nanoparticles were non-cytotoxic to HeLa cells, until they were irradiated with a NIR laser, which led to intracellular doxorubicin release and hyperthermia. This induced a remarkable reduction in HeLa cells viability.The authors gratefully acknowledge financial support from the Spanish Government [Projects MAT2015-64139-C4-1-R, AGL2015-70235-C2-2-R and SAF2017-84689-R (MINECO/AEI/FEDER, UE)], the Generalitat Valenciana (Project PROMETEO2018/024) and European Union (Erasmus Mundus Programme, Action 2, grant agreement number 2014-0870/001001). A.H. thanks the Erasmus Mundus Programme for his PhD scholarship through the EuroInkaNet project. A.L.-L. thanks "La Caixa" Banking Foundation for his PhD scholarship.Hernández-Montoto, A.; Llopis-Lorente, A.; Gorbe, M.; Terrés-Haro, JM.; Cao Milán, R.; Díaz De Greñu-Puertas, B.; Alfonso-Navarro, M.... (2019). Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery. Chemistry - A European Journal. 25(36):8471-8478. https://doi.org/10.1002/chem.201900750S847184782536Yang, P., Gai, S., & Lin, J. (2012). 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Interactive models of communication at the nanoscale using nanoparticles that talk to one another. Nature Communications, 8(1). doi:10.1038/ncomms15511Song, N., & Yang, Y.-W. (2015). Molecular and supramolecular switches on mesoporous silica nanoparticles. Chemical Society Reviews, 44(11), 3474-3504. doi:10.1039/c5cs00243eAznar, E., Oroval, M., Pascual, L., Murguía, J. R., Martínez-Máñez, R., & Sancenón, F. (2016). Gated Materials for On-Command Release of Guest Molecules. Chemical Reviews, 116(2), 561-718. doi:10.1021/acs.chemrev.5b00456Koutsopoulos, S. (2012). Molecular fabrications of smart nanobiomaterials and applications in personalized medicine. Advanced Drug Delivery Reviews, 64(13), 1459-1476. doi:10.1016/j.addr.2012.08.002Bao, G., Mitragotri, S., & Tong, S. (2013). Multifunctional Nanoparticles for Drug Delivery and Molecular Imaging. 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Nutritional Supplementation to Increase Influenza Vaccine Response in Children Living With HIV: A Pilot Clinical Trial

AimsVaccine response is poor among children living with HIV. The gut microbiota has been identified as a potential target to improve vaccine immunogenicity, but data are scarce in the context of HIV infection.MethodsPilot, double-blind, randomized placebo-controlled trial in which 24 HIV-infected children were randomized to receive a mixture of symbiotics, omega-3/6 fatty acids, and amino acids or placebo for 4 weeks, each in combination with ART, and were then immunized against influenza. Vaccine response and safety of the nutritional supplementation were the primary outcomes.ResultsEighteen HIV-infected children completed the follow-up period (mean age 11.5 ± 4.14 years, 61% female). The nutritional supplement was safe but did not enhance the response to the influenza vaccine. A 4-fold rise in antibody titers was obtained in only 37.5% of participants in the intervention arm vs. 40% in the placebo. No immunological or inflammatory predictors of vaccine response were identified.ConclusionsIn this exploratory study, a 4-week course of symbiotics did not increase influenza vaccine immunogenicity in HIV-infected children. Larger studies are warranted to address the potential of modulating the microbiome in children living with HIV