9 research outputs found

    Alternativas de Monitoreo de Calidad de Aguas: Algas como Bioindicadores

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    El uso de indicadores biol´ogicos de contaminaci´on se ha incrementado en los´ultimos a˜nos, como una alternativa de monitoreo de calidad de las aguas. El concepto de bioindicador, las razones para su empleo as´ı como las caracter´ısticas quedeben tener los organismos indicadores son consideradas en este art´ıculo. Se utiliza como caso espec´ıfico de referencia, el uso de algas como bioindicadores decontaminaci´on por metales en ecosistemas acu´aticos

    CC8 MRSA Strains Harboring SCCmec Type IVc are Predominant in Colombian Hospitals

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    BACKGROUND: Recent reports highlight the incursion of community-associated MRSA within healthcare settings. However, knowledge of this phenomenon remains limited in Latin America. The aim of this study was to evaluate the molecular epidemiology of MRSA in three tertiary-care hospitals in Medellín, Colombia. METHODS: An observational cross-sectional study was conducted from 2008-2010. MRSA infections were classified as either community-associated (CA-MRSA) or healthcare-associated (HA-MRSA), with HA-MRSA further classified as hospital-onset (HAHO-MRSA) or community-onset (HACO-MRSA) according to standard epidemiological definitions established by the U.S. Centers for Disease Control and Prevention (CDC). Genotypic analysis included SCCmec typing, spa typing, PFGE and MLST. RESULTS: Out of 538 total MRSA isolates, 68 (12.6%) were defined as CA-MRSA, 243 (45.2%) as HACO-MRSA and 227 (42.2%) as HAHO-MRSA. The majority harbored SCCmec type IVc (306, 58.7%), followed by SCCmec type I (174, 33.4%). The prevalence of type IVc among CA-, HACO- and HAHO-MRSA isolates was 92.4%, 65.1% and 43.6%, respectively. From 2008 to 2010, the prevalence of type IVc-bearing strains increased significantly, from 50.0% to 68.2% (p = 0.004). Strains harboring SCCmec IVc were mainly associated with spa types t1610, t008 and t024 (MLST clonal complex 8), while PFGE confirmed that the t008 and t1610 strains were closely related to the USA300-0114 CA-MRSA clone. Notably, strains belonging to these three spa types exhibited high levels of tetracycline resistance (45.9%). CONCLUSION: CC8 MRSA strains harboring SCCmec type IVc are becoming predominant in Medellín hospitals, displacing previously reported CC5 HA-MRSA clones. Based on shared characteristics including SCCmec IVc, absence of the ACME element and tetracycline resistance, the USA300-related isolates in this study are most likely related to USA300-LV, the recently-described 'Latin American variant' of USA300

    Colombian consensus recommendations for diagnosis, management and treatment of the infection by SARS-COV-2/ COVID-19 in health care facilities - Recommendations from expert´s group based and informed on evidence

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    La Asociación Colombiana de Infectología (ACIN) y el Instituto de Evaluación de Nuevas Tecnologías de la Salud (IETS) conformó un grupo de trabajo para desarrollar recomendaciones informadas y basadas en evidencia, por consenso de expertos para la atención, diagnóstico y manejo de casos de Covid 19. Estas guías son dirigidas al personal de salud y buscar dar recomendaciones en los ámbitos de la atención en salud de los casos de Covid-19, en el contexto nacional de Colombia

    Ecotoxicological tools in support of the aims of the European Water Framework Directive: A step towards a more holistic ecosystem-based approach

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    The Water Framework Directive (WFD) aims to attain ‘good quality’ status for all European water bodies through the achievement of good ecological status. To this purpose, the WFD advocates the creation of cost-effective monitoring tools to deliver appropriate data that help to create links between chemical and ecological indicators, as those from ecotoxicological research. Here, it was evaluated whether the integration of ecotoxicological tools, as bioassays and biomarkers, did (or did not) strengthen the robustness of the assessment of the ecological status obtained through well stablished biotic indices in two Atlantic estuaries. For that, a battery of in-situ bioassays, including five macroinvertebrate species (the crab Carcinus maenas, the amphipod Echinogammarus marinus, the isopod Cyathura carinata, the snail Peringia ulvae and the polychaete Hediste diversicolor, each one providing complementary information regarding key ecological functions) and a set of biomarkers, was used. In addition, the concentrations of heavy metals in sediments, and in macroalgae (Fucus), were determined, along with sediment granulometric, water physicochemical and nutrients characterization. We show that by interpreting the values of all indicators together, along with environmental components, it is possible to perform a more holistic description of the quality status of a waterbody – and, to begin to allude to factors limiting that quality. Ecotoxicological tools (in situ bioassays and biomarkers) appear to provide an added value of useful information for monitoring programmes regarding the true state - within which, both known and unknown contaminants are potentially present at concentrations sufficient to cause biological effects. Our results support the use of in situ bioassays and biomarkers within protocols aimed at fulfilling the goals of the WFD. In doing so, more complete and informative assessments of the ecological quality status of water bodies can take place
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