Una aproximación a la articulación de la producción familiar diversificada en los territorios locales del sur de Santa Fe

Este trabajo busca analizar las articulaciones que pueden establecerse entre opciones productivas y las dinámicas de los territorios, analizando particularmente el tipo y grado de inserción social y económica de la agricultura familiar diversificada a los territorios locales. Se pondrá especial atención a los vínculos económicos entre producción agropecuaria y espacios locales, ya que resulta un aspecto fundamental para comprender las lógicas territoriales que se desprenden de la producción agropecuaria actual. Se presentan los avances de un estudio en curso, realizado con productores familiares diversificados, en tanto actores que sostienen una lógica socio-productiva relativamente alternativa al modelo agrario dominante, y se enfatiza en la existencia y características de vínculos con otros actores económicos locales y extralocales y en los motivos que explican esos vínculos desde el punto de vista de los actores. Esta primera aproximación empírica al tema, exploratoria, analiza tres casos de producción familiar diversificada (de rasgos que resultan prototípicos) situados en el departamento de Constitución, en el sur santafecino, zona de fuerte especialización productiva (agrícola, particularmente sojera) perteneciente a la llamada “zona núcleo” de la región pampeana.Mesa 28: El vapor del diablo. Sociedad, trabajo y ambiente en el capitalismo agrario de los siglos XX y XXIFacultad de Humanidades y Ciencias de la Educació

Una aproximación a la articulación de la producción familiar diversificada en los territorios locales del sur de Santa Fe

Este trabajo busca analizar las articulaciones que pueden establecerse entre opciones productivas y las dinámicas de los territorios, analizando particularmente el tipo y grado de inserción social y económica de la agricultura familiar diversificada a los territorios locales. Se pondrá especial atención a los vínculos económicos entre producción agropecuaria y espacios locales, ya que resulta un aspecto fundamental para comprender las lógicas territoriales que se desprenden de la producción agropecuaria actual. Se presentan los avances de un estudio en curso, realizado con productores familiares diversificados, en tanto actores que sostienen una lógica socio-productiva relativamente alternativa al modelo agrario dominante, y se enfatiza en la existencia y características de vínculos con otros actores económicos locales y extralocales y en los motivos que explican esos vínculos desde el punto de vista de los actores. Esta primera aproximación empírica al tema, exploratoria, analiza tres casos de producción familiar diversificada (de rasgos que resultan prototípicos) situados en el departamento de Constitución, en el sur santafecino, zona de fuerte especialización productiva (agrícola, particularmente sojera) perteneciente a la llamada “zona núcleo” de la región pampeana.Mesa 28: El vapor del diablo. Sociedad, trabajo y ambiente en el capitalismo agrario de los siglos XX y XXIFacultad de Humanidades y Ciencias de la Educació

Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents

We synthesized five novel tryptamine derivatives characterized by the presence of an azelayl chain or of a 1,1,1-trichloroethyl group, in turn connected to another heterocyclic scaffold. The combination of tryptamin-, 1,1,1-trichloroethyl- and 2-aminopyrimidinyl- moieties produced compound 9 identified as the most active compound in hematological cancer cell lines (IC50 = 0.57–65.32 M). Moreover, keeping constant the presence of the tryptaminic scaffold and binding it to the azelayl moiety, the compounds maintain biological activity. Compound 13 is still active against hematological cancer cell lines and shows a selective effect only on HT29 cells (IC50 = 0.006 M) among solid tumor models. Compound 14 loses activity on all leukemic lines, while showing a high level of toxicity on all solid tumor lines tested (IC50 0.0015–0.469 M)

Towards a Global Tree Assessment

Although trees have high economic, cultural and ecological value, increasing numbers of species are potentially at risk of extinction because of forest loss and degradation as a result of human activities, including overharvesting, fire and grazing. Emerging threats include climate change and its interaction with the spread of pests and diseases. The impact of such threats on the conservation status of trees is poorly understood. Here we highlight the need to conduct a comprehensive conservation assessment of the world's tree species, building on previous assessments undertaken for the IUCN Red List. We suggest that recent developments in plant systematics, online databases, remote sensing data and associated analytical tools offer an unprecedented opportunity to conduct such an assessment. We provide an overview of how a Global Tree Assessment could be achieved in practice, through participative, open-access approaches to data sharing and evaluation

Soyuretox, an intrinsically disordered polypeptide derived from soybean (Glycine max) ubiquitous urease with potential use as a biopesticide

Ureases from different biological sources display non-ureolytic properties that contribute to plant defense, in addition to their classical enzymatic urea hydrolysis. Antifungal and entomotoxic effects were demonstrated for Jaburetox, an intrinsically disordered polypeptide derived from jack bean (Canavalia ensiformis) urease. Here we describe the properties of Soyuretox, a polypeptide derived from soybean (Glycine max) ubiquitous urease. Soyuretox was fungitoxic to Candida albicans, leading to the production of reactive oxygen species. Soyuretox further induced aggregation of Rhodnius prolixus hemocytes, indicating an interference on the insect immune response. No relevant toxicity of Soyuretox to zebrafish larvae was observed. These data suggest the presence of antifungal and entomotoxic portions of the amino acid sequences encompassing both Soyuretox and Jaburetox, despite their small sequence identity. Nuclear Magnetic Resonance (NMR) and circular dichroism (CD) spectroscopic data revealed that Soyuretox, in analogy with Jaburetox, possesses an intrinsic and largely disordered nature. Some folding is observed upon interaction of Soyuretox with sodium dodecyl sulfate (SDS) micelles, taken here as models for membranes. This observation suggests the possibility for this protein to modify its secondary structure upon interaction with the cells of the affected organisms, leading to alterations of membrane integrity. Altogether, Soyuretox can be considered a promising biopesticide for use in plant protection.Fil: Kappaun, Karine. Pontificia Universidade Católica do Rio Grande do Sul; BrasilFil: Martinelli, Anne H. S.. Universidade Federal do Rio Grande do Sul; BrasilFil: Broll, Valquiria. Universidade Federal do Rio Grande do Sul; BrasilFil: Zambelli, Barbara. Universidad de Bologna; ItaliaFil: Lopes, Fernanda C.. Universidade Federal do Rio Grande do Sul; BrasilFil: Ligabue-Braun, Rodrigo. Universidade Federal do Rio Grande do Sul; BrasilFil: Fruttero, Leonardo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Moyetta, Natalia Rita. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Bonan, Carla D.. Pontificia Universidade Católica do Rio Grande do Sul; BrasilFil: Carlini, Célia Regina R. S.. Pontificia Universidade Católica do Rio Grande do Sul; BrasilFil: Ciurli, Stefano. Universidad de Bologna; Itali

Novos registros de entedoníneos (Hymenoptera, Eulophidae) para a cultura do café (Coffea arabica L.)

The first cases of Emersonella pubipennis Hansson, 2002, Emersonella planiceps Hansson, 2002, Omphale huggerti (Hansson, 1988), Chrysocharis caribea Boucek, 1977, Chrysocharis vonones (Walker, 1839) and Chrysocharis tristis Hansson, 1987 (Hymenoptera, Eulophidae, Entedoninae) were reported for Coffea arabica L. based on specimens collected in Cravinhos (21°18’S/47°47’W), State of São Paulo, Brazil. The first occurrence of E. pubipennis and O. huggerti were also reported in Brazil. The insects were collected with Moericke and light traps between May of 2005 and April of 2007.São relatadas as primeiras ocorrências de Emersonella pubipennis Hansson, 2002, Emersonella planiceps Hansson, 2002, Omphale huggerti (Hansson, 1988), Chrysocharis caribea Boucek, 1977, Chrysocharis vonones (Walker, 1839) e Chrysocharis tristis Hansson, 1987 (Hymenoptera, Eulophidae, Entedoninae) na cultura do café Coffea arabica L., com base em exemplares coletados em Cravinhos (21°18’S/47°47’O), SP. Trata-se também dos primeiros relatos de ocorrência de E. pubipennis e O. huggerti para o Brasil. Tais insetos foram coletados com armadilhas de Moericke e luminosas entre maio de 2005 e abril de 2007

Identifying key factors that encourage vegetable intake by young adults: using the health belief model

Purpose: Adequate vegetable consumption is fundamental to a healthy balanced diet; however, global compliance with recommendations is poor which is particularly important for young adults as they form food consumption habits. There is a growing interest in the circular economy of hospitality and sustainability of current dietary patterns in light of climate change and an expanding global population. The food value chain needs to be considered both vertically and horizontally where the research and development (R&D) investment is optimised by being “joined up” and not fragmentary; in addition, consumer trade-offs of health vs for example sensory appeal are taken into consideration. The purpose of this study was to identify factors predicting acceptance of vegetable dishes by young adults and present a roadmap that can be used for dish development and healthful marketing. Design/methodology/approach: This study used the health belief model (HBM) as framework to investigate key factors that encourage vegetable intake by young adults using an online questionnaire sample of 444 enrolled in undergraduate programs at universities in Brazil. Findings: Structural modelling showed that vegetable consumption frequency was positively influenced by Health concerns, Naturalness and Self-efficacy (including cooking skills), whereas Sensory factors and Familiarity demonstrated a negative loading that might be related to unpleasantness. Originality/value: Globally, there is a strong need to promote the consumption of vegetables as a public health policy priority but also to ameliorate barriers to action that could be facilitated by availability, dish development and healthful marketing in hospitality operations

Programa Conectar Igualdad -Seguimiento y evaluación

El presente documento tiene por propósito presentar los lineamientos de seguimiento y evaluación del Programa CONECTAR IGUALDAD, en particular el componente de estudios especiales

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types