14 research outputs found

    A study of lactobacilli from the normal vagina and various gynaecological conditions.

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    The purpose of this study was to compare the species of Lactobacillus present in the vagina of gynaecologically normal women with those isolated from women with certain gynaecological conditions. Fifty-nine strains, isolated from gynaecologically normal women, and seventeen reference strains were characterised by 71 morphological, biochemical and nutritional tests. Groups of isolates, produced by computer-aided principal components and cluster analyses of the data, correlated well with the species identification, made according to a few conventionally used tests. The species of Lactobacillus isolated most frequently were L. acidophilus (35.6 per cent.), L. jensenii (23.7 per cent.) and L. fermentum (15.3 per cent.). Antisera raised against representatives of these species showed that L. jensenii, a species previously reported from this habitat only twice and little studied, was serologically distinct from the other isolates. Lactobacilli were also isolated from women with four gynaecological conditions, namely infections with Candida albicans and Trichomonas vaginalis respectively, pregnancy and abnormalities of the uterine cervix. These isolates were speciated using a reduced list of characterisation tests. No significant differences were found between the species of Lactobacillus from these women and those from gynaecologically normal women. No relationship could be established between the forms of lactobacilli isolated and clinical characteristics or other microorganisms isolated from the vagina. Women from whom lactobacilli were not isolated had a significantly higher vaginal pH and greater incidence of potentially pathogenic organisms. Estimations of the abundance of vaginal isolates showed that some organisms were consistently present in greater numbers than others. Individual species of Lactobacillus also showed definite tendencies to be present in particular grades of abundancy

    Risk assessment on use of Lactobacillus rhamnosus (LGG) as an ingredient in infant formula and baby foods (II)

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    Source at https://vkm.no/On 10. March 2006 , The Norwegian Food Safety Authority (Mattilsynet) decided that, on the basis of VKM’s previous risk assessment (2005), Nutramigen 1 with Lactobacillus rhamnosus GG (LGG) could not be marketed in Norway as medical foods for infants (0-4 months). In addition, The Norwegian Food Safety Authority (Mattilsynet) decided (08. November 2006) to withdraw permission for marketing ofNutramigen 2 with LGG, which is a milk supplement for infants aged between 4 and 6 months, with cow’s milk and soy protein allergy. On 13. December 2006, Mead Johnson Nutritionals appealed against this decision from The Norwegian Food SafetyAuthority (Mattilsynet). The Norwegian Food Safety Authority forwarded the appeal from the companies, asked the VKM Panel on biological hazards and the VKM Panel on nutrition, dietetic products, novel food and allergy, for a new risk assessment including the new data provided in the appeal.Basert på VKMs tidligere risikovurdering fra 2005, bestemte Mattilsynet 10. mars 2006 atNutramigen 1 med LGG ikke kunne markedsføres som næringsmiddel til spesielle medisinske formål (0-4 måneder) i Norge. I tillegg trakk Mattilsynet tilbake tillatelsen (08. november, 2006) til å markedsføre Nutramigen 2 med LGG, som er en melkeerstatning for spedbarn mellom fire og seks måneder som er allergiske mot kumelk og soyaproteiner. Den 13. desember 2006 Mead Johnson Nutritionals på vedtaket fra Mattilsynet. Mattilsynet videresendte klagen fra selskapene og ba VKMs faggrupper for hygiene og smittestoffer samt ernæring, dietetiske produkter, ny mat og allergi om å foreta en ny risikovurdering basert på nye data som er lagt frem i forbindelse med klagen
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