Breus’ mole/chorangiosis/chorangioma of the placenta: a dilemma with a rare fetal outcome report

Massive Subchorionic Thrombohematoma (MST) is a rare condition in which there is a massive collection of blood between the placental membranes and uterine wall separating the villous chorionic plate from villous chorion. It is relatively rare and is poorly understood. Many theories have been proposed to explain the etiology of Breus mole; some suggest it is a fetal haemorrhage, while others claim it has a maternal-origin thrombosis of placental vessels. A 30-year-old healthy Indian pregnant woman was presented at Max Hospital, Shalimar Bagh Delhi, India, during her second pregnancy with a complaint of fever. On routine level-2 ultrasonography (USG) done at 18.6 weeks of gestation showed thick placenta. No fetal tumours or any other anomalies were noted on that scan which was followed by a detailed scan which confirmed a solitary mass arising from fetal side 103x64x82 mm S/O chorioangioma. Serial growth and doppler USG were conducted to monitor placental function, tumor characteristics and future anatomy. The subject received steroids to enhance fetal lungs maturation at Week 30, iron/calcium supplements, Ecosprin tablets, and progesterone support. At 32.5 weeks, the subject developed deranged sugars followed by gestational hypertension at 34.1 weeks. Ultrasonography also showed fetal growth restriction with large chorioangioma. The subject underwent a successful elective caesarean section at 34.4 weeks. On placental examination, 10 cm large mass encasing ¾ of the placenta was identified as a large subchorionic hematoma/chorioangioma (800 g). This study concludes that early identification of a large chorangioma aids in consequent fetal surveillance, management of maternal symptoms, and delivery planning discussions even if the pathological diagnosis turns out to be Breus’ mole with underlying chorangiosis postnatally

Generalized seizures during cataract surgery following peribulbar block: A case report

Local anesthesia techniques are commonly used to perform the cataract surgery. Among these techniques, peribulbar anesthesia(PBA), when compared to retrobulbar anesthesia, is more effective and safe. However, PBA is not without risk. Complications mayarise which if not recognized early and resuscitated, can be fatal. A 70-year-old Indian female was admitted for cataract extractionand lens implant in her left eye. Lignocaine sensitivity was done and showed no abnormal reaction. She developed generalized tonicclonicconvulsions following peribulbar block. This case report attempts to highlight the need for a trained personnel, compliancewith safety standards in anesthesia, awareness, and early recognition of the possible complications and their management

Concise Information for the Frontline Health care workers in the era of COVID-19

Background: COVID-19, a disease caused by SARS-CoV-2 has become a public health emergency of worldwide concern. Originated in Wuhan District of China, it has spread globally at a very rapid rate causing millions of deaths worldwide. Aims and Objectives: To summarize findings from all the current literature available from different databases regarding the epidemiological, clinical characteristics, laboratory diagnosis, treatment, prevention and control of the SARS-CoV-2. This will help out the reader to have a fine gist of all the data available on SARS-CoV-2 in an effective manner. Methods: All the research literature from Jan-March 2020 and available on the following online databases: bio-Rxiv, PubMed, Google Scholar, Embase as well as CNKI and Wang Fang data were included in the review. The keywords used for data search were “coronavirus,” “nCoV,” “2019-nCoV,” and “COVID-19.” Conclusion: After undergoing extensive literature search, it can be concluded that it mainly effects elderly male population. Mode of transmission is droplet transmission and human to human transmission is present. The main diagnostic modality remains molecular assays though several rapid testing methods are on the way. Due to lack of specific treatment guidelines, Infection control and supportive treatment remain the mainstay. Plethora of experiments are under trails for development of effective vaccine which can be a ray of hope in future