Notes on sphere-based universal extra dimensions

Hideto Dohi, Takuya Kakuda, Kenji Nishiwaki, Kin-ya Oda, Naoya Okuda. Notes on sphere-based universal extra dimensions. https://arxiv.org/abs/1406.1954

Higgs at ILC in Universal Extra Dimensions in Light of Recent LHC Data

We present bounds on all the known universal extra dimension models from the latest Higgs search data at the Large Hadron Collider, taking into account the Kaluza-Klein (KK) loop effects on the dominant gluon-fusion production and on the diphoton/digluon decay. The lower bound on the KK scale is from 500GeV to 1TeV depending on the model. We find that the Higgs production cross section with subsequent diphoton decay can be enhanced by a factor 1.5 within this experimental bound, with little dependence on the Higgs mass in between 115GeV and 130GeV. We also show that in such a case the Higgs decay branching ratio into a diphoton final state can be suppressed by a factor 80%, which is marginally observable at a high energy/luminosity option at the International Linear Collider. The Higgs production cross section at a photon-photon collider can also be suppressed by a similar factor 90%, being well within the expected experimental reach.Takuya Kakuda, Kenji Nishiwaki, Kin-ya Oda, Naoya Okuda, Ryoutaro Watanabe. Higgs at ILC in Universal Extra Dimensions in Light of Recent LHC Data. https://arxiv.org/abs/1202.6231

Heavy Higgs at Tevatron and LHC in Universal Extra Dimension Models

Universal Extra Dimension (UED) models tend to favor a distinctively heavier Higgs mass than in the Standard Model (SM) and its supersymmetric extensions when the Kaluza-Klein (KK) scale is not much higher than the electroweak one, which we call the weak scale UED, in order to cancel the KK top contributions to the T-parameter. Such a heavy Higgs, whose production through the gluon fusion process is enhanced by the KK top loops, is fairly model independent prediction of the weak scale UED models regardless of the brane-localized mass structure at the ultraviolet cutoff scale. We study its cleanest possible signature, the Higgs decay into a Z boson pair and subsequently into four electrons and/or muons, in which all the four-momenta of the final states can be measured and both the Z boson masses can be checked. We show that the weak scale UED model may account for the 2sigma excess of this event at ATLAS at the ZZ pair invariant mass around 250GeV, at which scale SM background is sufficiently small and the SM Higgs predicts too few events. We have also studied the Higgs mass 500GeV (and also 700GeV with \sqrt{s}=14TeV) and have found that we can observe significant resonance with the integrated luminosity 10fb^{-1} for six dimensional UED models.Comment: (v1) 36 pages, 9 figures, 6 tables; (v2) Accepted for publication in Phys. Rev. D, factor 2 error in (93) corrected, comments and references added, figures redrawn; (v3) Minor changes including typo corrections in eq.(15), final version appearing in PR

A bound on Universal Extra Dimension Models from up to 2fb^{-1} of LHC Data at 7TeV

The recent up to 2fb^{-1} of data from the ATLAS and CMS experiments at the CERN Large Hadron Collider at 7TeV put an upper bound on the production cross section of a Higgs-like particle. We translate the results of the H -> WW -> l nu l nu and H -> gamma gamma as well as the combined analysis by the ATLAS and CMS into an allowed region for the Kaluza-Klein (KK) mass M_{KK} and the Higgs mass $M_H$ for all the known Universal Extra Dimension (UED) models in five and six dimensions. Our bound is insensitive to the detailed KK mass splitting and mixing and hence complementary to all other known signatures.Comment: (v2) accepted for publication in Phys. Lett. B, newer data shown in Lepton-Photon conference (especially from separate WW and di-photon channels) are included, title changed accordingly, comments and references added; (v1) 10 pages, 2 figures, 2 table

The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine Working Group Database

金沢大学医薬保健研究域医学系Purpose The Japanese Society of Nuclear Medicine (JSNM) working group has created a myocardial perfusion imaging database applicable to standard acquisition protocol. The aim of this study is to validate the diagnostic accuracy of the common normal database compared with the expert interpretation of each institute. Methods Five institutions participated in this study and used different acquisition settings which included 360°/ 180° rotation, camera configuration and camera orbits. The software and its version used in each institution also varied. The working group database was applied to detect the culprit coronary territory from a total of 166 patients with coronary artery disease (CAD) and 145 patients with lowlikelihood of CAD. Results When summed stress score C4 was defined as significant abnormality, overall sensitivity, specificity and accuracy of patient-based analysis were 77, 72 and 75%, respectively, based on quantitative analysis using the common database, whereas those by institutional visual expert reading were 72, 79 and 75%, respectively. Conclusion The common database, which was created by a multi-center working group and separated between male/ female with 180/360° acquisitions, demonstrated comparable diagnostic accuracy to expert interpretation by each institute, and it may be applicable to multi-center studies

The Conformal Transformation in General Single Field Inflation with Non-Minimal Coupling

The method of a conformal transformation is applied to a general class of single field inflation models with non-minimal coupling to gravity and non-standard kinetic terms, in order to reduce the cosmological perturbative calculation to the conventional minimal coupling case to all orders in perturbation theory. Our analysis is made simple by the fact that all perturbation variables in the comoving gauge are conformally invariant to all orders. The structure of the vacuum, on which cosmological correlation functions are evaluated, is also discussed. We show how quantization in the Jordan frame for non-minimally coupled inflation models can be equivalently implemented in the Einstein frame. It is thereafter argued that the general N-point cosmological correlation functions (of the curvature perturbation) are independent of the conformal frame.Comment: 15 pages, no figure, references adde

Early passenger leukocyte migration and acute immune reactions in the rat recipient spleen during liver engraftment: With particular emphasis on donor major histocompatibility complex class II⁺ cells

After a short course of tacrolimus, Lewis rat liver allografts induce donor-specific nonreactivity in Brown Norway recipients that is immunosuppression-independent after 28 days. To clarify the role of donor major histocompatibility complex (MHC) class II+ cells, we investigated the migration to the recipient splenic T- and B-cell compartments of different subsets of Lewis MHC class II+ passenger leukocytes. The rise and decline of immune activation were monitored in the hepatic allograft and in the host spleen by analyses of BrdU+ (proliferating) leukocytes, TUNEL+ (apoptotic) cells, apoptosis-associated molecules, TH1/TH2 cytokine profiles, and histoimmunocytochemical examination of graft and splenic tissues. Serial flow cytometry studies during the 28-day period of drug-assisted "hepatic tolerogenesis" showed that migratory MHC class II+ cells accounted for less than half of the donor cells in the host spleen. The class II+ cells consisted mostly of B cells that homed to splenic B-cell follicles with only a sparse representation of dendritic cells that were exclusively found in the splenic periarteriolar lymphoid sheath. In parallel studies, transplantation of the less tolerogenic heart produced a diminutive version of the same events, but with far fewer donor cells in the host spleen, evidence of sustained immune activation, and the development of chronic rejection by 100 days. The data are consistent with the paradigm that migration of donor leukocytes is the prime determinant of variable tolerance induction induced by transplantation of the liver and other organs, but without regard for donor MHC class II+ expression

Immunomodulation for intestinal transplantation by allograft irradiation, adjunct donor bone marrow infusion, or both.

BACKGROUND: The passenger leukocytes in the intestine have a lineage profile that predisposes to graft-versus-host disease (GVHD) in some animal models and have inferior tolerogenic qualities compared with the leukocytes in the liver, other solid organs, and bone marrow. Elimination by ex vivo irradiation of mature lymphoid elements from the bowel allografts is known to eliminate the GVHD risk. We hypothesized that infusion of donor bone marrow cells (BMC) in recipients of irradiated intestine would improve tolerogenesis without increasing the risk of GVHD. METHODS: Orthotopic small intestine transplantation was performed with the GVHD-prone Lewis (LEW)-to-Brown Norway (BN) combination and the reverse GVHD-resistant BN-to-LEW model under a short course of tacrolimus treatment (1 mg/kg/day, days 0-13, 20, 27). Grafts were irradiated ex vivo, using a 137Cs source. In selected experimental groups, donor BMC (2.5 x 10(8)) were infused on the day of small intestine transplantation. RESULTS: The unmodified LEW intestine remained intact, whether transplanted alone or with adjunct donor BMC infusion, but all of the BN recipients died of GVHD after approximately 2 months. Intestinal graft irradiation (10 Gy) effectively prevented the GVHD and prolonged survival to 92.5 days, but all of the BN recipients died with chronic rejection of the LEW grafts, which was prevented by infusion of adjunct donor BMC without causing GVHD. In the GVHD-resistant reverse strain direction (BN-->LEW), all intestinal recipients treated for 27 days with tacrolimus survived > or =150 days without regard for graft irradiation or adjunct BMC, but chronic rejection was severe in the irradiated intestine, moderate in the unaltered graft, and least in the irradiated intestine transplanted with adjunct BMC. Mild arteritis in the 150 day allografts of both strain combinations (i.e., LEW--> BN and BN-->LEW) may have been irradiation associated, but this was prevented when weekly doses of tacrolimus were continued for the duration of the experiment rather than being stopped at 27 days. CONCLUSIONS: Recipients are protected from GVHD by irradiating intestinal allografts, but the resulting leukocyte depletion leads to chronic rejection of the transplanted bowel. The chronic rejection is prevented with adjunct donor BMC without causing GVHD. Although application of the strategy may be limited by the possibility of radiation injury, the results are consistent with the paradigm that we have proposed to explain organ-induced graft acceptance, tolerance, and chronic rejection