The deuteronomic view of history in second temple Judaism

The Babylonian Exile was a historical catalyst compelling Jewish authors of the Second Temple period to deal with their respective situations in the course of history according to – or against – various predicaments from which they suffered in an unprecedented manner. Second Temple Jews were faced with the most fundamental uneasiness: it seemed that God abandoned his people owing to their breaking of the covenant. Therefore, it was important to reconceptualise their worldview into which creation, history, and covenant could be incorporated and which could vouchsafe the ongoing relationship with God to their respective situations. Intradisciplinary and/or interdisciplinary implications: In this article, the worldview of Second Temple Judaism is reflected on by observing how different communities in Second Temple Judaism engaged the Song of Moses in Deuteronomy 31–32. This article focusses on the interpretations of this passage in Second Temple Judaism, with specific reference to selected texts from Qumran, Tobit, the Testament of Moses, Philo, Josephus and Sifre Deuteronomy. Implicated disciplines are Old Testament studies, Apocryphal studies, Dead Sea Scroll studies and New Testament studies.https://verbumetecclesia.org.zapm2020Old Testament Studie

New Approach for Measuring ∣Vub∣|V_{ub}| at Future BB-Factories

It is suggested that the measurements of hadronic invariant mass ($m_X$) distributons in the inclusive $B \rightarrow X_{c(u)} l \nu$ decays can be useful in extracting the CKM matrix element $|V_{ub}|$. We investigated hadronic invariant mass distributions within the various theoretical models of HQET, FAC and chiral lagrangian as well as ACCMM model. It is also emphasized that the $m_X$ distribution even at the region $m_{X} > m_{D}$ in the inclusive $b\rightarrow u$ are effetive in selecting the events, experimentally viable at the future asymmetric $B$ factories, with better theoretical understandings.Comment: 11 pages not including 1 figur

Test of Factorization Hypothesis from Exclusive Non-leptonic B decays

We investigate the possibility of testing factorization hypothesis in non-leptonic exclusive decays of B-meson. In particular, we considered the non factorizable \bar{B^0} -> D^{(*)+} D_s^{(*)-} modes and \bar{B^0} -> D^{(*)+} (\pi^-, \rho^-) known as well-factorizable modes. By taking the ratios BR(\bar{B^0}-> D^{(*)+}D_s^{(*)-})/BR(\bar{B^0}-> D^{(*)+}(\pi^-,\rho^-)), we found that under the present theoretical and experimental uncertainties there's no evidence for the breakdown of factorization description to heavy-heavy decays of the B meson.Comment: 11 pages; submitted to PR

Dependence of Variational Perturbation Expansions on Strong-Coupling Behavior. Inapplicability of delta-Expansion to Field Theory

We show that in applications of variational theory to quantum field theory it is essential to account for the correct Wegner exponent omega governing the approach to the strong-coupling, or scaling limit. Otherwise the procedure either does not converge at all or to the wrong limit. This invalidates all papers applying the so-called delta-expansion to quantum field theory.Comment: Author Information under http://www.physik.fu-berlin.de/~kleinert/institution.html . Latest update of paper (including all PS fonts) at http://www.physik.fu-berlin.de/~kleinert/34

Arsenic Trioxide Modulates DNA Synthesis and Apoptosis in Lung Carcinoma Cells

Arsenic trioxide, the trade name Trisenox, is a drug used to treat acute promyleocytic leukemia (APL). Studies have demonstrated that arsenic trioxide slows cancer cells growth. Although arsenic influences numerous signal-transduction pathways, cell-cycle progression, and/or apoptosis, its apoptotic mechanisms are complex and not entirely delineated. The primary objective of this research was to evaluate the effects of arsenic trioxide on DNA synthesis and to determine whether arsenic-induced apoptosis is mediated via caspase activation, p38 mitogen–activated protein kinase (MAPK), and cell cycle arrest. To achieve this goal, lung cancer cells (A549) were exposed to various concentrations (0, 2, 4, 6, 8, and 10 μg/mL) of arsenic trioxide for 48 h. The effect of arsenic trioxide on DNA synthesis was determined by the [3H]thymidine incorporation assay. Apoptosis was determined by the caspase-3 fluorescein isothiocyanate (FITC) assay, p38 MAP kinase activity was determined by an immunoblot assay, and cell-cycle analysis was evaluated by the propidium iodide assay. The [3H]thymidine-incorporation assay revealed a dose-related cytotoxic response at high levels of exposure. Furthermore, arsenic trioxide modulated caspase 3 activity and induced p38 MAP kinase activation in A549 cells. However, cell-cycle studies showed no statistically significant differences in DNA content at subG1 check point between control and arsenic trioxide treated cells

Severe vitamin D deficiency in 6 Canadian First Nation formula-fed infants

Background. Rickets was first described in the 17th century and vitamin D deficiency was recognized as the underlying cause in the early 1900s. Despite this long history, vitamin D deficiency remains a significant health concern. Currently, vitamin D supplementation is recommended in Canada for breast fed infants. There are no recommendations for supplementation in formula-fed infants. Objective. The objective of this report is to bring attention to the risk of severe vitamin D deficiency in high risk, formula fed infants. Design. A retrospective chart review was used to create this clinical case series. Results. Severe vitamin D deficiency was diagnosed in six formula-fed infants over a two-and-a-half year period. All six infants presented with seizures and they resided in First Nation communities located at latitude 54 in the province of Manitoba. While these infants had several risk factors for vitamin D deficiency, they were all receiving cow's milk based formula supplemented with 400 IU/L of vitamin D. Conclusion. This report suggests that current practice with regards to vitamin D supplementation may be inadequate, especially for high-risk infants. Health care professionals providing service to infants in a similar situation should be aware of this preventable condition. Hopefully this would contribute to its prevention, diagnosis and management

Research productivity and academics’ conceptions of research

This paper asks the question: do people with different levels of research productivity and identification as a researcher think of research differently? It discusses a study that differentiated levels of research productivity among English and Australian academics working in research-intensive environments in three broad discipline areas: science, engineering and technology; social science and humanities; and medicine and health sciences. The paper explores the different conceptions of research held by these academics in terms of their levels of research productivity, their levels of research training, whether they considered themselves an active researcher and a member of a research team, and their disciplinary differences

Average Kinetic Energy of Heavy Quark in Semileptonic B Decay

Within the ACCMM model the average kinetic energy of heavy quark in a heavy-light meson is calculated as $\langle {\bf p}^2 \rangle = {3 \over 2} {p_{_F}}^2$, solely from the fact that the Gaussian momentum probability distribution has been taken in the ACCMM model. Therefore, the Fermi momentum parameter $p_{_F}$ of the ACCMM model is not a truly free parameter, but is closely related to the average kinetic energy of heavy quark, which is theoretically calculable in principle. In this context, we determine $p_{_F}$ by comparing the theoretical prediction of the ACCMM model with the model independent lepton energy spectrum of $B \rightarrow e \nu X$ from the recent CLEO analysis, and find that $p_{_F}=0.54~\pm~^{0.16}_{0.15}$ GeV. We also calculate $p_{_F}$ in the relativistic quark model by applying the quantum mechanical variational method, and obtained $p_{_F}=0.5\sim 0.6$ GeV. We show the correspondences between the relativistic quark model and the heavy quark effective theory. We then clarify the importance of the value of $p_{_F}$ in the determination of $|V_{ub}/V_{cb}|$.Comment: 23 pages(LaTeX), 2 Postscript figures, uses aps.st

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe