Test of Quantum Action for Inverse Square Potential

We present a numerical study of the quantum action previously introduced as a parametrisation of Q.M. transition amplitudes. We address the questions: Is the quantum action possibly an exact parametrisation in the whole range of transition times ($0 < T < \infty$)? Is the presence of potential terms beyond those occuring in the classical potential required? What is the error of the parametrisation estimated from the numerical fit? How about convergence and stability of the fitting method (dependence on grid points, resolution, initial conditions, internal precision etc.)? Further we compare two methods of numerical determination of the quantum action: (i) global fit of the Q.M. transition amplitudes and (ii) flow equation. As model we consider the inverse square potential, for which the Q.M. transition amplitudes are analytically known. We find that the relative error of the parametrisation starts from zero at T=0 increases to about $10^{-3}$ at $T=1/E_{gr}$ and then decreases to zero when $T \to \infty$. Second, we observe stability of the quantum action under variation of the control parameters. Finally, the flow equation method works well in the regime of large $T$ giving stable results under variation of initial data and consistent with the global fit method.Comment: Text (LaTeX), Figures(ps

Climbing to New Heights: Lessons From Mount Everest on PCI and TDI Convergence

This paper applies attitude theory to assess the influence of beliefs and evaluations of Nepal with desired linkages and travel intentions. The main contribution is to connect TDI and PCI research by testing a general country image model in a tourism context. Attitude theory acts as the connection between the two fields

Is Quantum Chaos Weaker Than Classical Chaos?

We investigate chaotic behavior in a 2-D Hamiltonian system - oscillators with anharmonic coupling. We compare the classical system with quantum system. Via the quantum action, we construct Poincar\'{e} sections and compute Lyapunov exponents for the quantum system. We find that the quantum system is globally less chaotic than the classical system. We also observe with increasing energy the distribution of Lyapunov exponts approaching a Gaussian with a strong correlation between its mean value and energy.Comment: text (LaTeX) + 7 figs.(ps

QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin

Background: There is no known effective therapy for patients with COVID-19. Initial reports suggesting the potential benefit of Hydroxychloroquine/Azithromycin (HY/AZ) have resulted in massive adoption of this combination worldwide. However, while the true efficacy of this regimen is unknown, initial reports have raised concerns regarding the potential risk of QT prolongation and induction of torsade de pointes (TdP). Objective: to assess the change in QTc interval and arrhythmic events in patients with COVID-19 treated with HY/AZ METHODS: This is a retrospective study of 251 patients from two centers, diagnosed with COVID-19 and treated with HY/AZ. We reviewed ECG tracings from baseline and until 3 days after completion of therapy to determine the progression of QTc and incidence of arrhythmia and mortality. Results: QTc prolonged in parallel with increasing drug exposure and incompletely shortened after its completion. Extreme new QTc prolongation to &gt; 500 ms, a known marker of high risk for TdP had developed in 23% of patients. One patient developed polymorphic ventricular tachycardia (VT) suspected as TdP, requiring emergent cardioversion. Seven patients required premature termination of therapy. The baseline QTc of patients exhibiting extreme QTc prolongation was normal. Conclusion: The combination of HY/AZ significantly prolongs the QTc in patients with COVID-19. This prolongation may be responsible for life threating arrhythmia in the form of TdP. This risk mandates careful consideration of HY/AZ therapy in lights of its unproven efficacy. Strict QTc monitoring should be performed if the regimen is given

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Mouse Chromosome 11

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46996/1/335_2004_Article_BF00648429.pd

Branding MBA programs: The use of target market desired outcomes for effective brand positioning

Branding is about delivering on desired outcomes. The importance of positioning program offerings on the basis of outcomes sought in the education market is illustrated in this study of choice of an MBA program by prospective students. MBA fair attendees were surveyed and multiple methods were employed to determine the importance of desired outcomes and the ratings of MBA programs on their ability to deliver these outcomes. In a highly competitive market, differentiation and effective positioning appear to be the keys to success of both the two competing business schools studied

China and the Olympics: Views of insiders and outsiders

Purpose: The purpose of this paper is to examine the views of residents and foreigners of the Olympics and the host country before and after the mega-event within the context of marketing theory on country image effects and psychology theories attribution. Design/methodology/approach: This is achieved by studying the views of American and Chinese respondents of China and the Olympics before and after the Beijing Olympics. Samples of Chinese and Americans were surveyed before and after the Beijing Summer Olympics concerning their images of the Olympics, China and its people, and China as a vacation destination. Cross-national and pre-post comparisons are made and interaction effects are noted using MANOVA. Findings: Significant cross-national and time differences and several interaction effects are found across all three focal objects of image measurements. Large country differences are found. Despite how technically successful the Games might have looked, post-event assessments are overwhelmingly lower. Additional differences in views and interaction effects are discussed in terms of the intended and unintended impacts of the event on local and foreign respondents. Research limitations/implications: Only one location in China and one foreign country are surveyed. Practical implications: The paper has important implications for both the effects of mega-events on country images and the effects of the host country on the event brand image. These issues have relevance for countries seeking to host mega-events and those who manage these events and make decision about where they will be held. Originality/value: This is the first cross-national study of the Olympics and their effects using before-and-after event measures. It also combines analyses of both the event and the place images from the perspectives of both those who live in the country and residents of other countries. Attribution theory is a useful reference theory for mega-event assessments

Linking place, mega-event and sponsorship evaluations

Purpose: Little research has examined sponsorship within the context of mega-event and related host images. This paper seeks to explore the relationships among country, destination, mega-event and sponsor images through the evaluations formed of each entity. Design/methodology/approach: Based on data collected from 291 Canadian consumers two months after the Beijing Olympics, a SEM model examines the relationships among consumer evaluations of the host country, the country as a destination, the mega-event itself and sponsors. Findings: Results support the hypothesized model and present a paradoxical situation for the Olympics hosted by China. While the overall country evaluation was found to have a strong and positive effect on its evaluation as a tourist destination and the destination evaluation has a subsequent positive relationship with Olympic evaluations, a direct and negative relationship between the evaluation of the country and of the Olympic Games was also supported. Research limitations/implications: Future research should examine the relationship among country, destination, mega-event and sponsor images in other mega-event and country contexts. In addition, the pattern of these relationships should be assessed longitudinally. Practical implications: This study provides evidence to show that the Olympic Games image is resilient and can thrive in challenging contexts. Further, sponsors can be assured that they are receiving value from Olympic sponsorships. Originality/value: These results extend previous literature on sponsorship evaluation into the large, global sponsor context. In addition, this study examines the role of the host country in understanding the influence of the mega-event on sponsor images