Twitter Sentiment Analysis

Social media continues to gain increased presence and importance in society. Public and private opinion about a wide variety of subjects are expressed and spread continually via numerous social media. Twitter is one of the social media that is gaining increased popular. Twitter offers organizations a fast and effective way to analyze customers‟ perspectives toward the critical to success in the marketplace. Developing a program for sentiment analysis is an approach to be used to computationally measure customers‟ perceptions. This paper reports on the design of a sentiment analysis extracting a vast amount of tweets. Prototyping is used in this development. Results classify customers‟ perspective via tweets into positive and negative which is represented in pie chart and html page. However, the program has planned to develop on web application system but due to limitation of Django which can be worked on Linux server or LAMP, for further this approach need to be done

Twitter Sentiment Analysis

Social media continues to gain increased presence and importance in society. Public and private opinion about a wide variety of subjects are expressed and spread continually via numerous social media. Twitter is one of the social media that is gaining increased popular. Twitter offers organizations a fast and effective way to analyze customers‟ perspectives toward the critical to success in the marketplace. Developing a program for sentiment analysis is an approach to be used to computationally measure customers‟ perceptions. This paper reports on the design of a sentiment analysis extracting a vast amount of tweets. Prototyping is used in this development. Results classify customers‟ perspective via tweets into positive and negative which is represented in pie chart and html page. However, the program has planned to develop on web application system but due to limitation of Django which can be worked on Linux server or LAMP, for further this approach need to be done

Non-erythropoietic erythropoietin derivatives protect from light-induced and genetic photoreceptor degeneration

Given the high genetic heterogeneity of inherited retinal degenerations (IRDs), a wide applicable treatment would be desirable to halt/slow progressive photoreceptor (PR) cell loss in a mutation-independent manner. In addition to its erythropoietic activity, erythropoietin (EPO) presents neurotrophic characteristics. We have previously shown that adeno-associated viral (AAV) vector-mediated systemic EPO delivery protects from PR degeneration. However, this is associated with an undesired hematocrit increase that could contribute to PR protection. Non-erythropoietic EPO derivatives (EPO-D) are available which allow us to dissect erythropoiesis's role in PR preservation and may be more versatile and safe than EPO as anti-apoptotic agents. We delivered in animal models of light-induced or genetic retinal degeneration either intramuscularly or subretinally AAV vectors encoding EPO or one of the three selected EPO-D: the mutant S100E, the helix A- and B-derived EPO-mimetic peptides. We observed that (i) systemic expression of S100E induces a significantly lower hematocrit increase than EPO and provides similar protection from PR degeneration, and (ii) intraocular expression of EPO-D protects PR from degeneration in the absence of significant hematocrit increase. On the basis of this, we conclude that erythropoiesis is not required for EPO-mediated PR protection. However, the lower efficacy observed when EPO or S100E is expressed intraocularly rather than systemically suggests that hormone systemic effects contribute to PR protection. Unlike S100E, EPO-mimetic peptides preserve PR only when given locally, suggesting that different EPO-D have a different potency or mode of action. In conclusion, our data show that subretinal delivery of AAV vectors encoding EPO-D protects from light-induced and genetic PR degeneration

¿Qué pasa si eres un artista mago?

Neste texto, propomos o conceito de artista mago. Buscamos definições de Magia e a estrutura do xamanismo para traçar pontos de contato entre Arte e Magia. Listamos exemplos de artistas (1) que são ligados a tradições mágicas ou que utilizam elementos destas tradições; (2) de artistas que têm práticas análogas à magia mesmo não sendo ligados a nenhuma tradição; e (3) de artistas magos propriamente que, conscientemente, utilizam procedimentos mágicos ou análogos em sua obra construindo uma espiritualidade criativa. Com estas aproximações pretendemos demonstrar que toda arte pode ser vista como uma espécie de magia.What is the relationship and the points of contact between Art and Magic? What is common to the artist and the shaman? The genealogy of the concept of magic and art are confronted by various points of view from anthropology and psychology to esoterism to investigate the possibility of magical art today and to what extent all art can be understood as a kind of magic

Le système EPOergique cérébral : caractérisation et implication dans la protection neuronale au cours de l'épileptogenèse

Our work performed in rats submitted to a severe status epilepticus (SE) is the first to provide evidence that reactive production of erythropoietin (Epo) by local astrocytes is the optimal condition to support the most vulnerable neuronal population, when combined with exogenous administration of Epo. The receptor mediating Epo-induced neuroprotection is believed to be composed of Epo receptor (Epo-R) and common β chain (βc). The absence of coordinated regulation that we noted between Epo-R and βc, throughout postnatal development and ageing on one hand, and in response to SE on the other hand, refute the hypothesis that βc may constitute part of receptor mediating neuroprotective effect of Epo.Notre travail de thèse est le premier à mettre en évidence chez le rat ayant subit un état de mal cérébral (EMC), que la production locale et réactionnelle d'érythropoïétine (Epo) par les astrocytes, quand elle est accompagnée de l'administration exogène d'Epo, représente une condition optimale pour le maintien des populations neuronales les plus fragiles. La neuroprotection induite par l'Epo implique un récepteur spécifique qui serait composé par l'association entre le récepteur à l'Epo (Epo-R) et la chaîne bêta commune (βc). L'absence de régulation coordonnée entre l'Epo-R et la βc que nous dénonçons, aussi bien dans des conditions physiologiques (développement et vieillissement du SNC) que physiopathologiques (EMC), est un argument fort permettant de réfuter l'hypothèse selon laquelle la βc constituerait une des sous-unités du récepteur de l'Epo impliqué dans la neuroprotection

Neuroprotective effects of erythropoietin in the rat hippocampus after pilocarpine-induced status epilepticus.

International audienceNeuroprotective functions of erythropoietin (Epo) are thought to involve a heteroreceptor composed of both Epo receptor (Epo-R) and common beta chain (betac). Here, we measured the response of hippocampal Epo system components (Epo, Epo-R and betac) during neurodegenerative processes following pilocarpine-induced status epilepticus (SE), and examined whether recombinant human Epo (rHuEpo) could support neuronal survival. We evidence that Epo is induced in astroglia following SE, in particular within areas displaying delayed neuronal death. In addition, we demonstrate for the first time that rHuEpo reduces considerably hippocampal neurodegeneration following SE. rHuEpo may thus supplement astroglial induction of Epo to promote enhanced hippocampal neuronal survival following SE. We also show that Epo-R is expressed by neurons and astrocytes mainly, while betac is barely detectable in basal conditions and induced in reactive microglia exclusively following SE. Altogether, our results suggest that Epo/rHuEpo exerts neuroprotection, through Epo-R signaling and independently of betac, and, therefore, may be anti-epileptogenic

Drought effect on urban plane tree ecophysiology and its isoprene emissions

International audienceUrban trees emit a wide range of biogenic Volatile Organic Compounds (bVOC). Some of these bVOC, like isoprene can react with atmospheric oxidants to form secondary compounds, such as ozone (O3) and secondary organic aerosols (SOA), which have impacts on air quality and climate. In addition, isoprene emissions are strongly influenced by environmental factors and urban sites are known as stressful environment, characterized for example by water scarcity. However, little is known on the contribution of urban trees to air quality, notably during drought periods. In a semi-controlled experiment, fourteen young plane trees (Platanus x hispanica, known as a strong isoprene emitter) were grown in containers, in an urban site (at Vitry-sur-Seine, near Paris), since 2020. In June 2022, half the trees were subjected to drought by total rainfall exclusion and by withholding watering. A comprehensive characterization of tree response to drought, including plant morphology (leaf density and area), water status (i.e., leaf water potential, δ13C isotopic composition) and physiology (stomatal conductance, net photosynthesis, leaf pigment contents, stress molecular markers, chlorophyll fluorescence) analyses, was undertaken along with the characterization of bVOC emissions by an original leaf scale method (portable GC-MS coupled to a leaf chamber). All together, these parameters provided relevant information on the relation between bVOC emissions and plant morphology, its water use efficiency and photosynthetic energy conversion.Shortly after the onset of drought, the isoprene emissions of the plane trees remained unchanged even though typical responses to drought stress were observed, such as partial stomatal closure leading to a decrease in carbon assimilation. With the progression of drought stress, progressive leaf shedding occurred. When almost completely defoliated, the trees emitted lower amounts of isoprene emissions likely due to disruption of the photosynthetic energy conversion process. Despite the moderate decrease in absolute isoprene emissions rates (as expressed per dry leaf mass) induced by the drought treatment on plane trees with nearly zero gas exchange, total emissions were strongly affected because defoliation significantly reduced the total leaf area. We emphasize that this phenomenon should be taken into account in atmospheric models especially in species highly subjected to drought induced defoliation. Here, a simple parameterisation of this effect on plane tree-bVOC emissions is proposed