1,327 research outputs found
Symbiotic stars in X-rays II: faint sources detected with XMM-Newton and Chandra
We report the detection, with and XMM-, of
faint, soft X-ray emission from four symbiotics stars that were not known to be
X-ray sources. These four object show a -type X-ray spectrum, i.e. their
spectra can be modeled with an absorbed optically thin thermal emission with
temperatures of a few million degrees. Photometric series obtained with the
Optical Monitor on board XMM- from V2416 Sgr and NSV 25735
support the proposed scenario where the X-ray emission is produced in a
shock-heated region inside the symbiotic nebulae.Comment: 5 pages, 1 figure, 2 tables; A&A publishe
Static and dynamic measures of human brain connectivity predict complementary aspects of human cognitive performance
In cognitive network neuroscience, the connectivity and community structure
of the brain network is related to cognition. Much of this research has focused
on two measures of connectivity - modularity and flexibility - which frequently
have been examined in isolation. By using resting state fMRI data from 52 young
adults, we investigate the relationship between modularity, flexibility and
performance on cognitive tasks. We show that flexibility and modularity are
highly negatively correlated. However, we also demonstrate that flexibility and
modularity make unique contributions to explain task performance, with
modularity predicting performance for simple tasks and flexibility predicting
performance on complex tasks that require cognitive control and executive
functioning. The theory and results presented here allow for stronger links
between measures of brain network connectivity and cognitive processes.Comment: 37 pages; 7 figure
Brain Modularity Mediates the Relation between Task Complexity and Performance
Recent work in cognitive neuroscience has focused on analyzing the brain as a
network, rather than as a collection of independent regions. Prior studies
taking this approach have found that individual differences in the degree of
modularity of the brain network relate to performance on cognitive tasks.
However, inconsistent results concerning the direction of this relationship
have been obtained, with some tasks showing better performance as modularity
increases and other tasks showing worse performance. A recent theoretical model
(Chen & Deem, 2015) suggests that these inconsistencies may be explained on the
grounds that high-modularity networks favor performance on simple tasks whereas
low-modularity networks favor performance on more complex tasks. The current
study tests these predictions by relating modularity from resting-state fMRI to
performance on a set of simple and complex behavioral tasks. Complex and simple
tasks were defined on the basis of whether they did or did not draw on
executive attention. Consistent with predictions, we found a negative
correlation between individuals' modularity and their performance on a
composite measure combining scores from the complex tasks but a positive
correlation with performance on a composite measure combining scores from the
simple tasks. These results and theory presented here provide a framework for
linking measures of whole brain organization from network neuroscience to
cognitive processing.Comment: 47 pages; 4 figure
Brief retrospection on Hungarian school atlases
Abstract. The first part of this article is dedicated to the history of Hungarian school atlases to the end of the 1st World War. Although the first maps included in a Hungarian textbook were probably made in 1751, the publication of atlases for schools is dated almost 50 years later, when professor ĂzsĂĄiĂĄs Budai created his âNew School Atlas for elementary pupilsâ in 1800. This was followed by a long period of 90 years, when the school atlases were mostly translations and adaptations of foreign atlases, the majority of which were made in German-speaking countries. In those years, a school atlas made by a Hungarian astronomer, Antal VĂĄllas, should be highlighted as a prominent independent piece of work. In 1890, a talented cartographer, ManĂł Kogutowicz founded the Hungarian Geographical Institute, which was the institution responsible for producing school atlases for the different types of schools in Hungary. The professional quality of the school atlases published by his institute was also recognized beyond the Hungarian borders by prizes won in international exhibitions. Kogutowicz laid the foundations of the current Hungarian school cartography: this statement is confirmed in the second part of this article, when three of his school atlases are presented in more detail to give examples of how the pupils were introduced to the basic cartographic and astronomic concepts as well as how different innovative solutions were used on the maps.
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Abandono y adopciĂłn de animales de compañĂa
Treball presentat a l'assignatura de Deontologia i VeterinĂ ria Legal (21223
Communications in flexible supervisor for laboratory research in renewable energy
In laboratories new systems are created where researchers hope to obtain improved functions at a reasonable cost. In them, specialists need efficient tools that offer better performance and flexible features. This paper designs and implements a SCADA system for GERA laboratory (Scientific Group for Applied Renewable Energy at the University of Oriente) adjusted to the inherent characteristics of flexibility and functionality required in research centers. All these features are supported in an efficient communication system with the implementation of various protocols and novel solutions for this type of systems for monitoring and control. It verifies and validates the system for formal methods
Nucleic acid templated synthesis of peptide bonds
The conventional synthesis of peptides, by reactions performed under highly concentrated conditions or on solid phase, have been widely utilised to produce a variety of oligomers. This has facilitated the discovery of bioactive compounds and the mechanistic study of their function. Recently, nanotechnology has facilitated the synthesis of peptide bonds by directing the interactions between reactive groups, in order to produce the desired peptides. This thesis focuses on the use of nucleic acid templated synthesis (NATS) of peptide bonds, and on overcoming the hydrolysis of activated ester-labelled nucleic acids in aqueous solutions.
Chapter 1 gives a general overview of peptide bond formation strategies, highlighting nanotechnological approaches. The current scope and limitations of nucleic acid templated synthesis are also discussed. Chapter 2 is focused on the use of deep eutectic solvents (DESs) to minimise hydrolysis of activated esters, for the DNA templated synthesis (DTS) of peptide bonds. Chapter 3 describes the use of highly stable phenol ester-conjugated DNA adapters in aqueous buffered solution, and their in-situ activation towards aminolysis through oxo-ester mediated native chemical ligation (NCL). Chapter 4 explores if an alternative peptide nucleic acid (PNA) template could form stable duplexes in organic solvent, and thus, potentially template peptide bond synthesis reactions. Selective labelling of oligonucleotides has been a fundamental procedure in this thesis; in Appendix 2, the conjugation of fluorescent dibromomaleimide and dichloromaleimide to DNA has been explored; in addition, reductive amination has been explored as a chemistry for the modification of amine-labelled DNA with phenol esters
The impact of immersion in the acquisition of spanish verb structures: comparison of two siblings using different foreign language methods
Treballs Finals del Grau d'Estudis Anglesos, Facultat de Filologia, Universitat de Barcelona, Curs: 2015-2016 Tutor: Dr. Brian MottThe main question raised by this paper is aimed at discovering the impact that immersion has in the acquisition of Spanish verb structures. In order to study such an impact, the project is based on a comparison between two English monolingual siblings who study Spanish simultaneously, but who differ in the way they study it. While one sibling has studied Spanish in school for several years, the other one has had short time instruction, as well as a short time immersion period. The two siblings collaborated in the project by doing three carefully selected tasks focused on the tense, aspect and mood of the verbs found in each one of the proposed exercises. The results show that the sibling who has had an immersion period obtains better results than the sibling who has not. Thus, in this case study, immersion means a benefit in the acquisition of Spanish verb structures
Hypocretin/Orexin Neuropeptides: Participation in the Control of Sleep-Wakefulness Cycle and Energy Homeostasis
Hypocretins or orexins (Hcrt/Orx) are hypothalamic neuropeptides that are synthesized by neurons located mainly in the perifornical area of the posterolateral hypothalamus. These hypothalamic neurons are the origin of an extensive and divergent projection system innervating numerous structures of the central nervous system. In recent years it has become clear that these neuropeptides are involved in the regulation of many organic functions, such as feeding, thermoregulation and neuroendocrine and cardiovascular control, as well as in the control of the sleep-wakefulness cycle. In this respect, Hcrt/Orx activate two subtypes of G protein-coupled receptors (Hcrt/Orx1R and Hcrt/Orx2R) that show a partly segregated and prominent distribution in neural structures involved in sleep-wakefulness regulation. Wakefulness-enhancing and/or sleep-suppressing actions of Hcrt/Orx have been reported in specific areas of the brainstem. Moreover, presently there are animal models of human narcolepsy consisting in modifications of Hcrt/Orx receptors or absence of these peptides. This strongly suggests that narcolepsy is the direct consequence of a hypofunction of the Hcrt/Orx system, which is most likely due to Hcrt/Orx neurons degeneration
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