1,394 research outputs found
The National Security Implications and Potential Solutions for the Unintended Consequences of the 1980 Bayh-‐Dole Act on Brain-‐Injured Veterans from the Wars in Iraq and Afghanistan
Traumatic brain injury (TBI) is the “signature wound” seen in veterans from the wars in Iraq and Afghanistan, from which the U.S. now has over 20,000 young veterans living with TBI. However, some unintended consequences of the Bayh-‐Dole Act of 1980, a law designed to tap the “secret weapon” of federally funded research & development (R&D) to help the U.S. return to competitiveness after the recession of the late 1970’s, are now preventing these heroes from getting the treatment and cures they need. This article reviews the history of American academia’s close cooperation with the U.S. government in solving military medical problems from WWI through the Vietnam War, where those cures have now benefited millions worldwide. It then shows how this relationship has changed since the enactment of Bayh-‐Dole Act, and then examines the Act’s current and future impact on U.S. national security and the all-‐volunteer force. The article concludes that the Bayh-‐Dole Act should not be completely repealed, but recommends some amendments be enacted in order to take better care of the 1% of the U.S. population that fights and sacrifices to protect the other 99%
Solute transfer across the sediment surface of a eutrophic lake: I. Porewater profiles from dialysis samplers
Porewater profiles often are used to identify and quantify important biogeochemical processes occurring in lake sediments. In this study, multiple porewater profiles were obtained from two eutrophic Swiss lakes using porewater equilibrators (peepers) in order to examine spatial and seasonal trends in biogeochemical processes. Variability in profile shapes and concentrations was small on spatial scales of a few meters, but the uncertainty in calculated diffusive fluxes across the sediment surface was, on average, 35%. Focusing of Fe and Mn oxides toward the lake center resulted in systematic increases in porewater concentrations and diffusive fluxes of Fe2+ and Mn2+ with increasing water depth; these fluxes are postulated to be regulated by the pH-dependent dissolution of reduced-metal phases. Despite higher concentrations of inorganic carbon, NH 4 + , Si and P in pelagic compared to littoral sites, diffusive fluxes of these substances across the sediment surface increased only slightly or not at all with increasing water depth. Porewater profiles did reveal temporal changes in Fe2+, Mn2+, Ca2+ and Mg2+ that were an indirect result of the large, seasonal changes in seston deposition, but no clear seasonal variations were found in diffusive fluxes of nutrients across the sediment surface. The intense mineralization occurring at the sediment surface was not reflected in the porewater profiles nor in the calculated diffusive fluxes. Calculated diffusive fluxes across the sediment surface resulted from decomposition occurring primarily in the top 5-7 cm of sediment. Diffusive fluxes from this subsurface mineralization were equal to the solute release from mineralization occurring at the sediment-water interface. Buried organic matter acts as a memory of previous lake conditons; it will require at least a decade before reductions in nutrient inputs to lakes fully reduce the diffusive fluxes into the lake from the buried reservoir of organic matte
Testing the independence of maxima: from bivariate vectors to spatial extreme fields
International audienceCharacterizing the behaviour of multivariate or spatial extreme values is of fundamental interest to understand how extreme events tend to occur. In this paper we propose to test for the asymptotic independence of bivariate maxima vectors. Our test statistic is derived from a madogram, a notion classically used in geostatistics to capture spatial structures. The test can be applied to bivariate vectors, and a generalization to the spatial context is proposed. For bivariate vectors, a comparison to the test by Falk and Michel (2006) is conducted through a simulation study. In the spatial case, special attention is paid to pairwise dependence. A multiple test procedure is designed to determine at which lag asymptotic independence takes place. This new procedure is based on the bootstrap distribution of the number of times the null hypothesis is rejected. It is then tested on maxima of three classical spatial models and finally applied to two climate datasets
Rangewide Population Structure of the Clearnose Skate
Skates (family Rajidae) are benthic elasmobranchs that are highly vulnerable to incidental fishery bycatch, are dis-carded at sea, and are poorly accounted for in catch records. Many aspects of skate life history, such as population structure, are not well understood. Without this knowledge, indiscriminate removal may have deleterious effects on scientific, conservation, and management efforts. The Clearnose Skate Rostroraja eglanteriais seasonally migratory and widely distributed in the coastal waters of the eastern United States and in the northeastern Gulf of Mexico. This study used molecular techniques to assess the population structure of Clearnose Skate for use as a biological reference point for further research and management. Specimens were collected from 2014 to 2019 byfisheries-independent surveys. High-throughput genotyping-by-sequencing was used to identify single nucleotide polymorphisms, resulting in two data sets: one consisting of 8,914 loci (outlier and neutral) and the other comprised of 30 outlier loci. Results from all analyses and using both data sets indicated a high level of genetic differentiation between specimens from the Gulf of Mexico and specimens from the U.S East Coast. Using the outlier data set, a low but significant level of genetic differentiation was also found among specimens from the U.S. East Coast, with a subtle break near the North Carolina and South Carolina border. Genetic differences along the U.S. East Coast were spatially autocorrelated,indicating a latitudinal genetic gradient. The level of observed genetic differentiation between the Gulf of Mexico and the U.S. East Coast is likely due to physical barriers such as Florida and the Gulf Stream current, while the subtle structure along the U.S. East Coast is likely attributable to isolation caused by dispersal limitations and local temperature preferences. The results from this investigation of Clearnose Skate population structure can be used to better monitor and manage this vulnerable elasmobranch
Electron Transfer Catalysis of The Hydrogenolysis of Acyl Dicarbonyl Cyclopentadienyliron Complexes by Tributyltin Hydride
The conversion of acyl dicarbonyl cyclopentadienyliron compounds Cp(CO)2Fe(COR) into aldehydes is not straightforward. It is shown here, mainly from electrochemical results, that the hydrogenolysis of the metal acyl bond can be efficiently achieved by trialkytin hydrides under very mild conditions, according to a chain reaction process initiated by an electron transfer to the acyl complex. The expected aldehyde is formed together with the heterobinuclear iron-tin complex
Electron Transfer Catalysis of The Hydrogenolysis of Acyl Dicarbonyl Cyclopentadienyliron Complexes by Tributyltin Hydride
The conversion of acyl dicarbonyl cyclopentadienyliron compounds Cp(CO)2Fe(COR) into aldehydes is not straightforward. It is shown here, mainly from electrochemical results, that the hydrogenolysis of the metal acyl bond can be efficiently achieved by trialkytin hydrides under very mild conditions, according to a chain reaction process initiated by an electron transfer to the acyl complex. The expected aldehyde is formed together with the heterobinuclear iron-tin complex
Self-regulatory processes in goal striving during excellent distance-running performances: A qualitative study
El dumping y la importación de tejidos de China hacia el Perú en el periodo 2004 - 2013
El presente trabajo que tiene por título “El dumping y la importación de tejidos de China hacia el
Perú en el periodo 2004 – 2013” fue elaborado con la finalidad de conocer la influencia del
dumping, para poder cumplir con el objetivo se obtuvo información de distintas fuentes, Sunat,
Indecopi, PromPerú, Cámara de Comercio de Lima, instituciones peruanas relacionadas al
comercio exterior, bridando información mediante cuadros, gráficos, referencias y otros.
En la presente investigación también se muestra el análisis de los resultados que se obtuvieron,
como el volumen y valor de importación de tejidos de China hacia Perú que estuvo creciendo
durante un determinado período y que en el año 2010 sufrió una disminución por las medidas
antidumping impuestas por Indecopi mediante los reclamos de empresas afectadas del sector
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