816 research outputs found

    Variational calculations on the hydrogen molecular ion

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    We present high-precision non-relativistic variational calculations of bound vibrational-rotational state energies for the H2+H_2^+ and D2+D_2^+ molecular ions in each of the lowest electronic states of Σg\Sigma_g, Σu\Sigma_u, and Πu\Pi_u symmetry. The calculations are carried out including coupling between Σ\Sigma and Π\Pi states but without using the Born-Oppenheimer or any adiabatic approximation. Convergence studies are presented which indicate that the resulting energies for low-lying levels are accurate to about 101310^{-13}. Our procedure accounts naturally for the lambda-doubling of the Πu\Pi_u state.Comment: 23 pp., RevTeX, epsf.sty, 5 figs. Enhanced data in Table II, dropped 3 figs. from previous versio

    The Student Movement Volume 106 Issue 8: Cardinals Cheer, Thanksgiving is Here!

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    HUMANS Meet Your 2021-2022 AU Cardinals Men\u27s Basketball Team, Interviewed by: Timmy Duado What Are You Thankful For?, Interviewed by: Grace No Meet Your 2021-2022 AU Cardinals Women\u27s Basketball Team, Interviewed by: Taylor Uphus ARTS & ENTERTAINMENT Thanksgiving Film Recommendations!, Megan Napod The Harder They Fall , Hannah Cruse What is CATHARSIS?, Solana Campbell NEWS Andrews Autumn Conference on Science & Religion, Abigail Lee AUSA Hosts Open Gym, Karenna Lee Campus Concert Crawl, Abigail Lee IDEAS Hidden out of Season, Evin-Nazya Musgrove Risk and Reward in Squid Game , Yoel Kim The Necessity of Firearm Safety Education, Nathan Cheng PULSE Honors Testimony: Worship in the Church, Honors Student Productivity... (and Pronouns ), T Bruggemann Thanksgiving Traditions of Your Student Movement Editors, Alannah Tjhatra THE LAST WORD Thanksgiving Dinner and Communion, Alyssa Henriquezhttps://digitalcommons.andrews.edu/sm-106/1007/thumbnail.jp

    The Student Movement Volume 106 Issue 15: AU Theatre Wing Presents Pride and Prejudice

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    HUMANS Matchmaking by SASA - Details on the New Club Event!, Interviewed by: Irina Gagiu Meeting AU\u27s New Librarian, Katherine Van Arsdale Bell, Interviewed by: Grace No My Future Plans: Hannah Castillo, Interviewed by: Lauren Kim ARTS & ENTERTAINMENT Creative Spotlight: Students of the AU Theatre Wing, Interviewed by: Megan Napod New Artist Releases: Evin Nazya-Musgrove, Eli Wilson, & Jonathan Lutterodt, Solana Compbell The One Inch Barrier, Steven Injety NEWS Herbert Blomstedt Comes to Andrews University, Abigail Lee It\u27s for the Effect: A Student Response, Chris Ngugi Worship Concert, Healing Together , Andrew Pak IDEAS Are Attention Spans Decreasing?, Elizabeth Getahun Do I Have to Be a Parent?, Angelina Nesmith Naming the Familiar: Emotions, Experiences, & our Insufficient Language, Alexander Navarro PULSE Checking Out Rate My Professors , Gloria Oh Dorm Policies, Alannah Tjhatra Lessons I\u27ve Learned on My Year Abroad, Terika Williams THE LAST WORD A Friend, Taylor Uphushttps://digitalcommons.andrews.edu/sm-106/1014/thumbnail.jp

    The Student Movement Volume 106 Issue 6: Cold Weather, Hot Dogs: Students Feast at Fall Festival

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    HUMANS New Director of Innovation and Entrepreneurship: Interview with Matias Soto, Interviewed by: Grace No Our AUSA President: An Interview with Dongchan Kim, Interviewed by: Irina Gagiu The People Who Inspire Us, Taylor Uphus ARTS & ENTERTAINMENT Creative Spotlight: Matthew Jackson (aka Mateo Banks), Interviewed by: Adoniah Simon Current Favorites: November 2021, Kaela McFadden Dune : Ushering in an Era of Sci-Fi Majesty, Solana Campbell NEWS For Sure On This Shining Night : It Was a Concert to Remember, Andrew Pak Fall Festival 2021: Autumnal Celebrations at Andrews University, Abigail Lee How to Call to (Flu) Shots at Andrews University, Nathan Mathieu The Water Crisis in Benton Harbor, Brendan Syto IDEAS Abandoning the Earth, Nathan Cheng The Drug Decriminalization Conversation, Qualyn Robinson The Legacy of Colin Powell, Angelina Nesmith PULSE College on a Budget, Gloria Oh Spreading Kindness Daily, Wambui Karanja Starting the Conversation: The LGBTQ+ Community & the Adventist Church, Karenna Lee THE LAST WORD Politics and Humanity: Our First Steps Toward Resolution, Alyssa Henriquezhttps://digitalcommons.andrews.edu/sm-106/1005/thumbnail.jp

    Is DRE essential for the follow up of prostate cancer patients? A prospective audit of 194 patients

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    BACKGROUND: Prostate cancer follow up forms a substantial part of the urology outpatient workload. Nurse led prostate cancer follow up clinics are becoming more common. Routine follow-up may involve performing DRE, which may require training. OBJECTIVES: The aim of this audit was to assess the factors that influenced the change in the management of prostate cancer patients during follow up. This would allow us to pave the way towards a protocol driven follow up clinic led by nurse specialists without formal training in DRE. RESULTS: 194 prostate cancer patients were seen over a period of two months and all the patients had DRE performed on at least one occasion. The management was changed in 47 patients. The most common factor influencing this change was PSA trend. A change in DRE findings influenced advancement of the clinic visit in 2 patients. CONCLUSIONS: PSA is the most common factor influencing change in the management of these patients. Nurse specialists can run prostate cancer follow-up clinics in parallel to existing consultant clinics and reserve DRE only for those patients who have a PSA change or have onset of new symptoms. However larger studies are required involving all the subgroups of patients to identify the subgroups of patients who will require DRE routinely

    Family coordination in families who have a child with autism spectrum disorder

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    Little is known about the interactions of families where there is a child with autism spectrum disorder (ASD). The present study applies the Lausanne Trilogue Play (LTP) to explore both its applicability to this population as well as to assess resources and areas of deficit in these families. The sample consisted of 68 families with a child with ASD, and 43 families with a typically developing (TD) child. With respect to the global score for family coordination there were several negative correlations: the more severe the symptoms (based on the child’s ADOS score), the more family coordination was dysfunctional. This correlation was particularly high when parents had to play together with the child. In the parts in which only one of the parents played actively with the child, while the other was simply present, some families did achieve scores in the functional range, despite the child’s symptom severity. The outcomes are discussed in terms of their clinical implications both for assessment and for interventio

    Testis and Antler Dysgenesis in Sitka Black-Tailed Deer on Kodiak Island, Alaska: Sequela of Environmental Endocrine Disruption?

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    It had been observed that many male Sitka black-tailed deer (Odocoileus hemionus sitkensis) on Kodiak Island, Alaska, had abnormal antlers, were cryptorchid, and presented no evidence of hypospadias. We sought to better understand the problem and investigated 171 male deer for phenotypic aberrations and 12 for detailed testicular histopathology. For the low-lying Aliulik Peninsula (AP), 61 of 94 deer were bilateral cryptorchids (BCOs); 70% of these had abnormal antlers. Elsewhere on the Kodiak Archipelago, only 5 of 65 deer were BCOs. All 11 abdominal testes examined had no spermatogenesis but contained abnormalities including carcinoma in situ–like cells, possible precursors of seminoma; Sertoli cell, Leydig cell, and stromal cell tumors; carcinoma and adenoma of rete testis; and microlithiasis or calcifications. Cysts also were evident within the excurrent ducts. Two of 10 scrotal testes contained similar abnormalities, although spermatogenesis was ongoing. We cannot rule out that these abnormalities are linked sequelae of a mutation(s) in a founder animal, followed by transmission over many years and causing high prevalence only on the AP. However, based on lesions observed, we hypothesize that it is more likely that this testis–antler dysgenesis resulted from continuing exposure of pregnant females to an estrogenic environmental agent(s), thereby transforming testicular cells, affecting development of primordial antler pedicles, and blocking transabdominal descent of fetal testes. A browse (e.g., kelp) favored by deer in this locale might carry the putative estrogenic agent(s)

    The Brazilian higher education evaluation model: “SINAES” sui generis?

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    "Available online 29 November 2017"A study applied to the context of Higher Education (HE) accreditation and evaluation in Brazil. It discusses recent reforms within the context of the Brazilian evaluation model. The changes brought by the new resolutions published in 2016 have been presented, and a conceptual mapping of the HE evaluation model has been drawn. The objectives were to explain, longitudinally, the ways used by monitoring agencies/bodies to assess performance, and to assure a quality HE. The research methodology used a combination of multiple qualitative methods to present results as conceptual maps. The study may contribute to improving quality, based on best practices in the evaluated model.The authors are grateful to the Research Center for Political Science (CICP-Portugal) of the University of Minho and Coordination for the Improvement of Higher Education Personnel (CAPES-Brazil).info:eu-repo/semantics/publishedVersio

    Engaging Hashima: Memory Work, Site-Based Affects, and the Possibilities of Interruption

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    How is memory embodied, narrated, interrupted, and reworked? Here, we take a postphenomenological approach to memory work that is attentive to how site-based affects prompt and ossify, but also transmogrify, memory of place. With reference to an intensely traumatized, but also domesticated and entropied, environment—the island of Hashima, off the coast from Nagasaki City in Japan—we demonstrate the relevance and explanatory reach of culturally specific accounts of memory, time, and place; how an attentiveness to cultural context in the making of meaning helps mark out the epistemological violences that accrue around sites such as Hashima as objects of analysis in and of themselves; and the affective capacities of the materialities and forces that compose such sites, which can present a welter of surfaces and interiorities that are sensuously “felt” as memory

    Resolving the fibrotic niche of human liver cirrhosis at single-cell level.

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    Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available. To obtain a better understanding of the cellular and molecular mechanisms involved in disease pathogenesis and enable the discovery of therapeutic targets, here we profile the transcriptomes of more than 100,000 single human cells, yielding molecular definitions for non-parenchymal cell types that are found in healthy and cirrhotic human liver. We identify a scar-associated TREM2+CD9+ subpopulation of macrophages, which expands in liver fibrosis, differentiates from circulating monocytes and is pro-fibrogenic. We also define ACKR1+ and PLVAP+ endothelial cells that expand in cirrhosis, are topographically restricted to the fibrotic niche and enhance the transmigration of leucocytes. Multi-lineage modelling of ligand and receptor interactions between the scar-associated macrophages, endothelial cells and PDGFRα+ collagen-producing mesenchymal cells reveals intra-scar activity of several pro-fibrogenic pathways including TNFRSF12A, PDGFR and NOTCH signalling. Our work dissects unanticipated aspects of the cellular and molecular basis of human organ fibrosis at a single-cell level, and provides a conceptual framework for the discovery of rational therapeutic targets in liver cirrhosis.Includes Wellcome, BHF, MRC, BBSRC and NIHR
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