Responsible research and innovation: A manifesto for empirical ethics?

In 2013 the Nuffield Council on Bioethics launched their report Novel Neurotechnologies: Intervening in the Brain. The report, which adopts the European Commission's notion of Responsible Research and Innovation, puts forward a set of priorities to guide ethical research into, and the development of, new therapeutic neurotechnologies. In this paper, we critically engage with these priorities. We argue that the Nuffield Council's priorities, and the Responsible Research and Innovation initiative as a whole, are laudable and should guide research and innovation in all areas of healthcare. However, we argue that operationalising Responsible Research and Innovation requires an in-depth understanding of the research and clinical contexts. Providing such an understanding is an important task for empirical ethics. Drawing on examples from sociology, science and technology studies, and related disciplines, we propose four avenues of social science research which can provide such an understanding. We suggest that these avenues can provide a manifesto for empirical ethics.The paper derives from a project that was funded by Wellcome Trust (Wellcome Trust Biomedical Strategic Award 086034)

Peak into the Past - An Archaeo-Astronomy Summer School

Our landscape has been shaped by man throughout the millennia. It still contains many clues to how it was used in the past giving us insights into ancient cultures and their everyday life. Our summer school uses archaeology and astronomy as a focus for effective out-of-classroom learning experiences. It demonstrates how a field trip can be used to its full potential by utilising ancient monuments as outdoor classrooms. This article shows how such a summer school can be embedded into the secondary curriculum; giving advice, example activities, locations to visit, and outlines the impact this work has had.Comment: 11 pages, 10 figures, accepted for School Science Revie

Average high latitude magnetic field: Variations with interplanetary sector and with season. 2: Comparison of disturbance levels and discussion of ionospheric currents

Average high latitude magnetic field data from northern observatories are examined for three ranges of magnetic disturbance level, Kp = 1 minus to 1+,2 minus to 3+, and or = 4 minus. Except for 0-8h MLT, 55-78 deg invariant latitude, during away interplanetary magnetic field sectors, the variations between season and sector have the the same characteristics at all Kp ranges. Because the amplitude of sector differences is much larger at sunlit local times than in the midnight sector, it is concluded that the current system of Svalgaard (1973) is not adequate to describe the sector variations in magnetic disturbance, other current systems are discussed briefly. The disturbance morphology and seasonal variation at all Kp levels confirms the results of previous studies which indicate that latitudinally broad current systems and non-ionospheric sources are present in addition to latitudinally narrow electrojet currents. Comparison of data between Kp levels indicates that the Harang discontinuity shifts toward earlier MLT with increasing Kp level

Fatigue crack propagation in microcapsule toughened epoxy

The addition of liquid-filled urea-formaldehyde (UF) microcapsules to an epoxy matrix leads to significant reduction in fatigue crack growth rate and corresponding increase in fatigue life. Mode-I fatigue crack propagation is measured using a tapered doublecantilever beam (TDCB) specimen for a range of microcapsule concentrations and sizes: 0, 5, 10, and 20% by weight and 50, 180, and 460 micron diameter. Cyclic crack growth in both the neat epoxy and epoxy filled with microcapsules obeys the Paris power law. Above a transition value of the applied stress intensity factor, which corresponds to loading conditions where the size of the plastic zone approaches the size of the embedded microcapsules, the Paris law exponent decreases with increasing content of microcapsules, ranging from 9.7 for neat epoxy to approximately 4.5 for concentrations above 10 wt% microcapsules. Improved resistance to fatigue crack propagation, indicated by both the decreased crack growth rates and increased cyclic stress intensity for the onset of unstable fatigue-crack growth, is attributed to toughening mechanisms induced by the embedded microcapsules as well as crack shielding due to the release of fluid as the capsules are ruptured. In addition to increasing the inherent fatigue life of epoxy, embedded microcapsules filled with an appropriate healing agent provide a potential mechanism for self-healing of fatigue damage.published or submitted for publicationis peer reviewe

A frequency-selective feedback model of auditory efferent suppression and its implications for the recognition of speech in noise

The potential contribution of the peripheral auditory efferent system to our understanding of speech in a background of competing noise was studied using a computer model of the auditory periphery and assessed using an automatic speech recognition system. A previous study had shown that a fixed efferent attenuation applied to all channels of a multi-channel model could improve the recognition of connected digit triplets in noise [G. J. Brown, R. T. Ferry, and R. Meddis, J. Acoust. Soc. Am. 127, 943?954 (2010)]. In the current study an anatomically justified feedback loop was used to automatically regulate separate attenuation values for each auditory channel. This arrangement resulted in a further enhancement of speech recognition over fixed-attenuation conditions. Comparisons between multi-talker babble and pink noise interference conditions suggest that the benefit originates from the model?s ability to modify the amount of suppression in each channel separately according to the spectral shape of the interfering sounds

In situ poly(urea-formaldehyde) microencapsulation of dicyclopentadiene

Microencapsulated healing agents that possess adequate strength, long shelf-life, and excellent bonding to the host material are required for self-healing materials. Ureaformaldehyde microcapsules containing dicyclopentadiene were prepared by in situ polymerization in an oil-in-water emulsion that meet these requirements for self-healing epoxy. Microcapsules of 10-1000 ??m in diameter were produced by appropriate selection of agitation rate in the range of 200-2000 rpm. A linear relation exists between log(mean diameter) and log(agitation rate). Surface morphology and shell wall thickness were investigated by optical and electron microscopy. Microcapsules are composed of a smooth 160-220 nm inner membrane and a rough, porous outer surface of agglomerated urea-formaldehyde nanoparticles. Surface morphology is influenced by pH of the reacting emulsion and interfacial surface area at the core-water interface. High yields (80-90%) of a free flowing powder of spherical microcapsules were produced with a fill content of 83-92 wt% as determined by CHN analysis.published or submitted for publicationis peer reviewe

Preventing Plagiarism and Fostering Academic Integrity: A Practical Approach

Although plagiarism, cheating and academic integrity receive increased attention, literature provides little practical advice or strategies on how to approach these topics with students. In this paper we describe a case study in relation to an intervention we have developed to help our students prevent plagiarism and to foster academic integrity amongst our studentship. In the two hour workshop students are supported in gaining a deeper understanding of what plagiarism is and provides them with practical examples of how plagiarism can be avoided. In the context of the workshop plagiarism is discussed in its many forms of the intentional and unintentional stealing or appropriating of ideas that are not credited accordingly (Helgesson & Eriksson, 2015). The intervention also encompasses discussions around academic integrity and what academic integrity means in theory and in practice. The six steps in our intervention are a sorting activity (what is plagiarism?), the presentation of real cases (what is the impact of plagiarism?), practising to synthesise ideas (how can I prevent plagiarism), the role of plagiarism-detection software such as Turnitin (how can I check for plagiarism?), the formulation of an integrity code and a summary of the content covered in the session (what do I know now?). The intervention draws upon research and practical experiences and is designed in such a way that with adaptations it can be delivered to all levels of students and courses. Following the presentation of the individual elements of the workshop the article concludes with a brief outline of a research project in relation to our workshop, which will be used to inform our further development of the intervention but also to provide a more formal evaluation of its effectiveness