Commodity and Financial Networks in Regional Economics

The article discusses the relationship between commodity-production and financial network structures in the regional economy as dual conjugate systems. Material flows (raw materials, goods and so on) circulate in the commodity network as shown by Leontiev’s input-output balance model. Nonmaterial flows of property rights, money, and so on circulate in the financial network and reflect the movement of material objects in commodity networks. A network structure comprises closed and open circuits, which have fundamentally different characteristics: locally closed circuits meet local demand by supplying locally produced goods, thus ensuring self-reproduction of the local economy; open (or transit) circuits provide export-import flows. The article describes the mechanism of ‘internal’ money generation in closed circuits of commodity-production networks. The results of the theoretical study are illustrated by the calculations of closed and open circuit flows in the municipal economy model. Mutual settlements between the population and manufacturing enterprises are given in matrix form. It was found that the volume of the turnover in closed circuits of the municipal economic network model is about 28.5 % of the total turnover and can be provided by ‘internal’ non-inflationary money. The remaining 71.5 % of the total turnover correspond to the flows in the network’s open circuits providing export and import. The conclusion is made that in the innovation-driven economy, main attention should be given to the projects oriented towards domestic consumption rather than export supplies. The economy is based on internal production cycles in closed circuits. Thus, it is necessary to find the chains in the inter-industrial and inter-production relations which could become the basis of the production cycle. Money investments will complete such commodity chains and ‘launch’ the production cycle.The work has been prepared with the supprot of the Ural Federal University within the UrFU Program for the winners of the competition “Young Scientists of UrFU” No. 2.1.1.1-14/43

Base sequence dependent sliding of proteins on DNA

The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered. Referring to the case of the T7 RNA-polymerase, we show that the protein should follow a noise-influenced sequence-dependent motion which deviate from the standard random walk usually assumed. The general validity and the implications of the results are discussed.Comment: 12 pages, 3 figure

Use of biodegradable polycaprolactone matrix for filling bone defects (experimental study)

Background. There are unresolved issues in bone defect management associated with complications, invasiveness and long duration of treatment. The use of elastic implants made of bioactive biodegradable materials that take any form of defect could close many of them.The aim. To investigate features of reparative regeneration in filling bone defects with an elastic degradable implant made of polycaprolactone (PCL) with and without hydroxyapatite (HA).Materials and methods. The study was carried out on 10 adult mongrel dogs. A non-through cylindrical hole, 4 mm in diameter and 10 mm deep, was modeled in the upper third of the diaphysis of the tibia. The defects thus formed were filled with an elastic degradable implant made of polycaprolactone. In Group 1, HA was not added to polycaprolactone, while HA was added in dogs of Group 2. Radiographic and histological methods were used to study the results.Results. It was found that the tested materials did not cause toxic and allergic reactions, both local and general, during intravital observations and in post-mortem anatomical preparations. After 28 days in both series, the implant biodegraded and was replaced by bone tissue. The proportion of the bone component and the numerical density of microvessels in the defect zone in Group 2 were significantly higher than in Group 1.Conclusion. Elastic implants produced of polycaprolactone by electrospinning are biologically compatible, biodegradable and can be used to heal bone defects. Hydroxyapatite that was added stimulates the activity of osteogenesis

Changes of the body functions during long-term hypokinesia

Prolonged hypokinesis (100-170 days) studied in 2000 rats kept in cages limiting their mobility provoked considerable changes in the gaseous and energetic metabolism: an elevation of the total gaseous metabolism and of the rate of O2 requirement by the muscles (in the late periods of hypokinesis) and a change in the intensity of tissue respiration of the liver and myocardium. There also proved to be a reduction in the level of phosphorylation and separation of oxidative phosphorylation in the myocardium, liver, and partially in the skeletal muscle. Prolonged hypokinesia led to changes in tissue metabolism: a disturbance of development of the animals, a marked delay and an increase in the weight of the organism and the muscular system, and disturbances of the mineral and protein metabolism. Prolonged hypokinesis also lead to exhaustion of the hypothalamus-hypophysis-adrenal cortex system

Local Inhomogeneity in Asymmetric Simple Exclusion Processes with Extended Objects

Totally asymmetric simple exclusion processes (TASEP) with particles which occupy more than one lattice site and with a local inhomogeneity far away from the boundaries are investigated. These non-equilibrium processes are relevant for the understanding of many biological and chemical phenomena. The steady-state phase diagrams, currents, and bulk densities are calculated using a simple approximate theory and extensive Monte Carlo computer simulations. It is found that the phase diagram for TASEP with a local inhomogeneity is qualitatively similar to homogeneous models, although the phase boundaries are significantly shifted. The complex dynamics is discussed in terms of domain-wall theory for driven lattice systems.Comment: 11 pages, 5 figure

Impact of Transphyseal Elastic Nailing On the Histostructure of the Tibia in Growing Animals (Non-Randomized Controlled Experimental Study)

BACKGROUND: The use of intramedullary elastic nailing is a method of choice for prevention of complications in children with osteogenesis imperfecta. However, the morphology of the growing long bones in the conditions created was not investigated. AIM: The purpose of our experiment was to study the impact of elastic intramedullary nailing on the histostructure of long bones in their physiological growth. METHODS: Six mongrel dogs underwent intramedullary elastic transphyseal nailing of the intact tibia with two titanium wires. Six months after nailing, a light-optical microscopic and histomorphometric study of the operated and contralateral tibiae was performed. RESULTS: It was found that asymmetric lesion of the distal physis induces a decrease in the height of the distal epimetaphysis. Adaptive changes in the hyaline cartilage of both articular ends were revealed corresponding to the initial stage of chondropathy. Intramedullary nailing promotes an increase in the thickness of the compact bone and the volume of the trabecular bone. CONCLUSIONS: Elastic transphyseal nailing of the intact tibia has a shaping effect which is expressed by an increase in the volume of spongy and compact bone, adaptive changes in the hyaline cartilage. Asymmetric damage to growth zones should be avoided to prevent deformities

Optimizing the lithotripsy timing after drainage of the upper urinary tract in patients with urolithiasis and obstructive uropathy

Introduction. Timely unresolved upper urinary tract (UUT) obstruction in patients with infection can cause severe complications, such as sepsis, pyonephrosis and even death. There are no clear recommendations regarding the methods and timing of drainage. At the same time, this issue is still the subject of discussion in publications of recent years.Purpose of the study. To optimize the timing of lithotripsy after drainage of the UUT in patients with urolithiasis and obstructive uropathy (OU).Materials and methods. At the first stage, 90 patients with OU caused by the stone of the ureteropelvic junction underwent drainage of the UUT using a percutaneous nephrostomy. Subsequently, percutaneous nephrolithotripsy (PNLT) was performed at various times after drainage. The level of inflammatory markers (IL-8) and profibrotic factor (MCP-1) in the urine was determined. The calculated concentrations of urinary biomarkers were normalized by the level of urinary creatinine. Urine sampling for the analysis was carried out during and after the PCN placement (nephrostomy urine) 7 days later, and then once weekly before surgery. The coefficient K was calculated using a patented formula to evaluate the process of kidney remodeling. Urine sampling was performed for culture to determine the bacterial spectrum and antibiotic sensitivity.Results. The values of K ≤ 1.85 were observed in 11 patients of the group with OU (12.2%), K > 1.85 in 79 (87.8%) by day 21. The values of K ≤ 1.85 were achieved in 70 patients (88.6%) by day 28 and 4 patients (80.0%) by day 35. PNLT was performed on 21 days in patients with K ≤ 1.85 (11 patients), no complications were noted in the postoperative period., PNLT was performed in patients with K ≤ 1.85 (70 patients) by day 28, exacerbation of pyelonephritis and the development of chronic kidney disease were not noted. Six patients with values of K ˃ 1.85 underwent PNLT by day 28. In the postoperative period, all patients had an exacerbation of calculous pyelonephritis, 50% had a decrease in glomerular filtration rate within 3 months after surgery. The bacteria in urine were detected in 55 (61.0%) patients. Escherichia coli (63.0%), Proteus mirabilis (18.0%), Enterococcus faecalis (14.5%), Streptococcus haemolyticus (2.5%) were identified most often.Conclusion. The use of the developed remodeling index allows optimizing the surgery timing and minimizing the development of complications during the postoperative period. The presence of bacteria is associated with a long process of renal parenchymal remodeling

Commensurate-Incommensurate Phase Transitions for Multichain Quantum Spin Models: Exact Results

The behavior in an external magnetic field is studied for a wide class of multichain quantum spin models. It is shown that the magnetic field together with the interchain couplings cause commensurate-incommensurate phase transitions between the gapless phases in the ground state. The conformal limit of these models is studied and it is shown that the low-lying excitations for the incommensurate phases are not independent. A scenario for the transition from one to two space dimensions for the integrable multichain models is proposed. The similarities in the external field behavior for the quantum multichain spin models and a wide class of quantum field theories are discussed. The exponents for the gaps caused by relevant perturbations of the models are calculated.Comment: 23 pages, LaTeX, typos correcte

ЭФФЕКТИВНОЕ ЖИВОТНОВОДСТВО – СТРАТЕГИЯ АГРАРНОЙ ПОЛИТИКИ БЕЛАРУСИ

Livestock breeding – is the most important branch of agriculture and the main source of funds for development of industrial and social base of agro-industrial complex of the country, which ensures food security. The animal husbandry is facing few priority tasks. The first – to have a competitive breeds of farm animals and poultry, the second – to implement efficient technologies for management, feeding and reproduction of animals, and the third – to ensure the biological safety the branch. Measures in the resent years aimed at increase of efficiency of animal breeding branches provided more than 7.45 million tons of milk, 1662 thousand tons of meat of livestock and poultry (body weight) for production in 2015 from all the categories of farms. In the whole in the country 730 kg of milk and 120 kg of meat was produced, calculated per capita. According to these indicators, as well as according to the amount of high-value food protein of animal origin produced (90–100 g per person a day) Belarus is among the most advanced countries along with Canada, the US and other. These volumes of livestock production ensure domestic requirements and export potential of the republic. More than 56 % of milk and 30 % of meat produced in the country is exported to external market. According to experts opinion, about 60–65 % of dairy products and 45 % of meat produced in the country will be exported in the near future. The article analyzes the modern state, main results, priorities and problems of containment of increase of productive traits of farm animals in Belarus. Ways to improve the competitiveness of the industry, as well as rates of livestock production growth in the future are presented.Животноводство – важнейшая отрасль сельского хозяйства и основной источник финансовых средств для развития производственной и социальной базы агропромышленного комплекса страны, которая обеспечивает продовольственную безопасность. Перед животноводством стоит несколько приоритетных задач. Первая - иметь конкурентоспособные породы сельскохозяйственных животных и птицы, вторая – внедрить эффективные технологии содержания, кормления и воспроизводства животных, третья – обеспечить биологическую безопасность отрасли. Осуществляемые в течение последних лет мероприятия по повышению эффективности ведения отраслей животноводства позволили обеспечить производство в 2015 г. всеми категориями хозяйств более 7,45 млн т молока, 1662 тыс. т мяса скота и птицы (в живом весе). В расчете на душу населения в целом по республике произведено 730 кг молока и 120 кг мяса. По этим показателям, а также по производству  высокоценного пищевого белка животного происхождения (90–100 г на человека в сутки) Беларусь входит в число самых передовых стран, таких как Канада, США и др. Эти объемы производства животноводческой продукции обеспечивают внутренние потребности республики и экспортный потенциал. Более 56 % произведенного в стране молока и около 30 % мяса поставляется на внешний рынок. По мнению экспертов, около 60–65 % молочной продукции и 45 % мяса, производимых в стране,в ближайшем будущем будут отправляться на экспорт. В статье анализируется  современное состояние, основные результаты, приоритетные направления развития и проблемы сдерживания повышения продуктивных качеств животных Беларуси. Приводятся пути повышения конкурентоспособности отрасли, а также темпы прироста производства продукции животноводства на перспективу

Exact Free Energy Functional for a Driven Diffusive Open Stationary Nonequilibrium System

We obtain the exact probability $\exp[-L {\cal F}(\{\rho(x)\})]$ of finding a macroscopic density profile $\rho(x)$ in the stationary nonequilibrium state of an open driven diffusive system, when the size of the system $L \to \infty$. $\cal F$, which plays the role of a nonequilibrium free energy, has a very different structure from that found in the purely diffusive case. As there, $\cal F$ is nonlocal, but the shocks and dynamic phase transitions of the driven system are reflected in non-convexity of $\cal F$, in discontinuities in its second derivatives, and in non-Gaussian fluctuations in the steady state.Comment: LaTeX2e, RevTeX4, PiCTeX. Four pages, one PiCTeX figure included in TeX source fil