6,819 research outputs found
Doppler imaging of the young late-type star LO Pegasi (BD +22 4409) in September 2003
A Doppler image of the ZAMS late-type rapidly rotating star LO Pegasi, based
on spectra acquired between 12 and 15 September 2003, is presented. The Least
Square Deconvolution technique is applied to enhance the signal-to-noise ratio
of the mean rotational broadened line profiles extracted from the observed
spectra. In the present application, a unbroadened spectrum is used as a
reference, instead of a simple line list, to improve the deconvolution
technique applied to extract the mean profiles. The reconstructed image is
similar to those previously obtained from observations taken in 1993 and 1998,
and shows that LO Peg photospheric activity is dominated by high-latitude spots
with a non-uniform polar cap. The latter seems to be a persistent feature as it
has been observed since 1993 with little modifications. Small spots, observed
between ~ 10 and ~ 60 degrees of latitude, appears to be different with respect
to those present in the 1993 and 1998 maps.Comment: 21 pages, 10 figures, accepted by Monthly Notices of the Royal
Astronomical Societ
Microscopic description of Coulomb and nuclear excitation of multiphonon states in Ca + Ca collisions
We calculate the inelastic scattering cross sections to populate one- and
two-phonon states in heavy ion collisions with both Coulomb and nuclear
excitations. Starting from a microscopic approach based on RPA, we go beyond it
in order to treat anharmonicities and non-linear terms in the exciting field.
These anharmonicities and non-linearities are shown to have important effects
on the cross sections both in the low energy part of the spectrum and in the
energy region of the Double Giant Quadrupole Resonance. By properly introducing
an optical potential the inelastic cross section is calculated semiclassically
by integrating the excitation probability over all impact parameters. A
satisfactory agreement with the experimental results is obtained.Comment: 20 pages, 2 figures, revtex, to be published in Phys. Rev.
Excitation of Pygmy Dipole Resonance in neutron-rich nuclei via Coulomb and nuclear fields
We study the nature of the low-lying dipole strength in neutron-rich nuclei,
often associated to the Pygmy Dipole Resonance. The states are described within
the Hartree-Fock plus RPA formalism, using different parametrizations of the
Skyrme interaction. We show how the information from combined reactions
processes involving the Coulomb and different mixtures of isoscalar and
isovector nuclear interactions can provide a clue to reveal the characteristic
features of these states.Comment: 9 Pages, 8 figures, contribution to International Symposium On
Nuclear Physics, December 8-12, 2009,Bhabha Atomic Research Centre, Mumbai,
Indi
Autonomous planning tool for changeable assembly systems
Car manufacturers are expected to start series production of fuel cell vehicles within the next years. Simultaneously, other industries are pushing towards the utilization of fuel cells. Fuel cell manufacturers need to scale up production at the right time and react to changing product requirements with the ideal level and point of changeability. This complex task requires methods and tools for decision support. The authors present SkaliA, an autonomous planning tool, which generates guidelines for the efficient use of change enablers specific to an assembly system. The planning tool is demonstrated on the example of an assembly system for high pressure valves used in fuel cell applications
Microscopic calculations of double and triple Giant Resonance excitation in heavy ion collisions
We perform microscopic calculations of the inelastic cross sections for the
double and triple excitation of giant resonances induced by heavy ion probes
within a semicalssical coupled channels formalism. The channels are defined as
eigenstates of a bosonic quartic Hamiltonian constructed in terms of collective
RPA phonons. Therefore, they are superpositions of several multiphonon states,
also with different numbers of phonons and the spectrum is anharmonic. The
inclusion of (n+1) phonon configurations affects the states whose main
component is a n-phonon one and leads to an appreacible lowering of their
energies. We check the effects of such further anharmonicities on the previous
published results for the cross section for the double excitation of Giant
Resonances. We find that the only effect is a shift of the peaks towards lower
energies, the double GR cross section being not modified by the explicity
inclusion of the three-phonon channels in the dynamical calculations. The
latters give an important contribution to the cross section in the triple GR
energy region which however is still smaller than the experimental available
data. The inclusion of four phonon configurations in the structure calculations
does not modify the results.Comment: Revtex4, to be published in PR
Tracking active nests in solar-type pulsators: Ensemble starspot modelling of Kepler asteroseismic targets
The satellite Planetary Transits and Oscillations of stars (PLATO), due to be
launched late 2026, will provide us with an unprecedented sample of light
curves of solar-type stars that will exhibit both solar-type oscillations and
signatures of activity-induced brightness modulations. Solar-type pulsators
only have moderate levels of activity because high levels of activity inhibit
oscillations. This means that these targets represent a specific challenge for
starspot modelling. In order to assess the possibilities that PLATO will soon
open, we wish to characterise the morphology of active regions at the surface
of stars for which we also have a detection of solar-like acoustic
oscillations. In this context, we report the results of an ensemble starspot
modelling analysis of the Sun and ten solar-type pulsators observed by the
Kepler satellite. We implement a Bayesian starspot modelling approach based on
a continuous-grid model, accounting for the combined starspot and facular
contribution to activity-induced brightness modulations. From our analysis, we
find that several stars of our sample exhibit clear signatures of stable
longitudinal active nests while sharing activity levels and convection versus
rotation regimes similar to the solar regime. By searching for modulations in
the reconstructed starspot coverage, we found significant periodicities that we
identify as possible signatures of cyclic modulations similar to the
quasi-biennal oscillation or the Rieger cycle. We can infer the corresponding
intensity of the magnetic field at the bottom of the convective envelope based
on the hypothesis that internal magneto-Rossby waves acting on the tachocline
cause these modulations.Comment: 18 pages, 23 figures, accepted for publication in A&
Classification of specimen density in Laser Powder Bed Fusion (L-PBF) using in-process structure-borne acoustic process emissions
Currently, the laser powder bed fusion (L-PBF) process cannot offer a reproducible and predefined quality of the processed parts. Recent research on process monitoring focuses strongly on integrated optical measurement technology. Besides optical sensors, acoustic sensors also seem promising. Previous studies have shown the potential of analyzing structure-borne and air-borne acoustic emissions in laser welding. Only a few works evaluate the potential that lies in the usage during the L-PBF process.
This work shows how the approach to structure-borne acoustic process monitoring can be elaborated by correlating acoustic signals to statistical values indicating part quality. Density measurements according to Archimedes’ principle are used to label the layer-based acoustic data and to measure the quality. The data set is then treated as a classification problem while investigating the applicability of existing artificial neural network algorithms to match acoustic data with density measurements. Furthermore, this work investigates the transferability of the approach to more complex specimens
Notes on the anatomy and phylogenetic position of Eremias ercolinii Lanza & Poggesi 1975 (Reptilia Lacertidae)
Detailed examination of the only known specimen of Eremias ercolinii Lanza & Poggesi 1975 shows that it has affinities within the Ophisops-Mesalina clade and, on present evidence, is best regarded as a member of Mesalina Gray 1838. However, its exact phylogenetic position will only be confirmed when more material becomes available. Limb proportions and scale form suggest that Mesalina ercolinii probably spends time in low, dense vegetation
SOAP. A tool for the fast computation of photometry and radial velocity induced by stellar spots
We define and put at the disposal of the community SOAP, Spot Oscillation And
Planet, a software tool that simulates the effect of stellar spots and plages
on radial velocimetry and photometry. This paper describes the tool release and
provides instructions for its use. We present detailed tests with previous
computations and real data to assess the code's performance and to validate its
suitability. We characterize the variations of the radial velocity, line
bisector, and photometric amplitude as a function of the main variables:
projected stellar rotational velocity, filling factor of the spot, resolution
of the spectrograph, linear limb-darkening coefficient, latitude of the spot,
and inclination of the star. Finally, we model the spot distributions on the
active stars HD166435, TW Hya and HD189733 which reproduces the observations.
We show that the software is remarkably fast allowing several evolutions in its
capabilities that could be performed to study the next challenges in the
exoplanetary field connected with the stellar variability.Comment: 9 pages, 12 figures, 4 tables, accepted for publication in A&
3,3′-Diindolylmethane and paclitaxel act synergistically to promote apoptosis in HER2/neu human breast cancer cells
Background. HER2/neu positive breast tumors are difficult to treat. About 25 to 30% of invasive breast tumors overexpress the HER2/neu oncogene. These tumors are aggressive and become resistant to chemotherapeutic drugs. 3,3′-diindolylmethane (DIM), the active metabolite of indole-3-carbinol, a naturally occurring compound found in cruciferous vegetables, has been found to have anti-cancer properties in both humans and animals. DIM has been shown to induce cell cycle arrest and apoptosis in animal breast cancer models. Because HER2/neu overexpression confers resistance to paclitaxel, and DIM has anti-tumor effects, we hypothesized that DIM will enhance the cytotoxic effects of paclitaxel, a common taxane drug, on human Her2/neu breast cancer cells by potentiating its effect on cell cycle and stimulating apoptosis.
Methods. The MDA-MB-435eB1 human Her2/neu breast cancer cells were treated with varying concentrations of DIM and paclitaxel. The cells were analyzed at different time points (24, 48, and 72 h). Proliferation was measured by a commercial cell proliferation assay (Promega Procheck Assay). Cell-cycle analysis and apoptosis were determined by flow cytometry. Western blot analysis was performed on to determine the effect of DIM and/or paclitaxel on the proteins involved in apoptosis, and epidermal growth factor-induced activation of HER2/neu and ERK1/2 signaling proteins.
Results. Both DIM and paclitaxel exhibited time and concentration dependent inhibition of cell proliferation. TUNEL assay indicated that the combination also increased the number of apoptotic cells more than either agent alone. The presence of cleaved poly (ADPRibose) polymerase (PARP) significantly increased in the combination treatment, whereas Bcl-2 is decreased. DIM alone decreased the activation of the Her2/neu receptor; the combination decreased the activation of ERK1/ERK2.
Conclusions. DIM in combination with paclitaxel synergistically inhibits growth of Her2/neu human breast cancer cells through G2M phase cell-cycle arrest and induction of apoptosis/necrosis. The Her2/neu receptor and its downstream signaling protein ERK1/2 appear to be involved in DIM’s affect on cell growth and differentiation, whereas apoptosis appears to be mediated through the mitochondrial pathway (Bcl-2/ PARP). It appears DIM, a naturally occurring, nontoxic compound, may be a beneficial addition to a traditional (taxane-based) chemotherapy regimen
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