166 research outputs found

    Guaranteeing the homotopy type of a set defined by non-linear inequalities

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    This paper provides an effective method to create an abstract simplicial complex homotopy equivalent to a given set S described by non-linear inequalities (polynomial or not). To our knowledge, no other numerical algorithm is able to deal with this type of problem. The proposed approach divides S into subsets that have been proven to be contractible using interval arithmetic. The method is close to ÄŚech cohomology and uses the nerve theorem. Some examples illustrate the principle of the approach. This algorithm has been implemented

    Using interval arithmetic to prove that a set is path-connected

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    On Sufficient Conditions of the Injectivity: Development of a Numerical Test Algorithm via Interval Analysis

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    This paper presents a new numerical algorithm based on interval analysis able to verify that a continuously differentiable function is injective. The efficiency of the method is demonstrated by illustrative examples. These examples have been treated by a C++ solver which is made available

    State estimation of a dehydration process by interval analysis

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    This article presents a general methodology of state estimation by interval analysis in a dynamic system modeled by difference equations. The methodology is applied to a pineapple osmotic dehydration process, in order to predict the behavior of the process within a range of allowed perturbation. The paper presents simulations and validations

    Determination of set-membership identifiability sets

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    International audienceThis paper concerns the concept of set-membership identifiability introduced in \cite{jauberthie}. Given a model, a set-membership identifiable set is a connected set in the parameter domain of the model such that its corresponding trajectories are distinct to trajectories arising from its complementary. For obtaining the so-called set-membership identifiable sets, we propose an algorithm based on interval analysis tools. The proposed algorithm is decomposed into three parts namely {\it mincing}, {\it evaluating} and {\it regularization} (\cite{jaulin2}). The latter step has been modified in order to obtain guaranteed set-membership identifiable sets. Our algorithm will be tested on two examples

    Mind the Gap: Computing Finance-Neutral Output Gaps in Latin-American Economies

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    We compute a measure of the finance-neutral potential output for Colombia, Chile and Mexico. Our methodology is based on Borio et al (2013, 2014) and incorporates the cycle of credit, house prices and the real exchange rate on the computation of the output gap. The literature on business cycles in emerging market economies, particularly papers focusing on Latin American economies, has highlighted the importance of including shocks to the interest rate in world capital markets together with financial frictions; terms of trade fluctuations; and a procyclical government spending process. Our results show that around the financial crises of the 1990s the finance-neutral output gap behaved differently than the traditional measures observed by policymakers. In particular, gaps are higher before crises and lower after them

    Long Astral Microtubules and RACK-1 Stabilize Polarity Domains during Maintenance Phase in Caenorhabditis elegans Embryos

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    Cell polarity is a very well conserved process important for cell differentiation, cell migration, and embryonic development. After the establishment of distinct cortical domains, polarity cues have to be stabilized and maintained within a fluid and dynamic membrane to achieve proper cell asymmetry. Microtubules have long been thought to deliver the signals required to polarize a cell. While previous studies suggest that microtubules play a key role in the establishment of polarity, the requirement of microtubules during maintenance phase remains unclear. In this study, we show that depletion of Caenorhabditis elegans RACK-1, which leads to short astral microtubules during prometaphase, specifically affects maintenance of cortical PAR domains and Dynamin localization. We then investigated the consequence of knocking down other factors that also abolish astral microtubule elongation during polarity maintenance phase. We found a correlation between short astral microtubules and the instability of PAR-6 and PAR-2 domains during maintenance phase. Our data support a necessary role for astral microtubules in the maintenance phase of cell polarity
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