Organization of cell junctions in the peritoneal mesothelium

Intercellular junctions in the mesothelium of the visceral (mesentery and omentum), and parietal (diaphragm, pre-aortic, and iliac region) peritoneum were examined in rats and mice by using freeze-cleaved preparations. In addition to usual intercellular junctions (cell body junctions), special junctions are found between cell processes and the surface of the neighboring cell (cell process junctions). Cell body junctions are provided with tight junctions and communicating (gap) junctions. The former consist of one to two junctional strands which show a characteristic staggered arrangement, and focal discontinuities. In cell process junctions, the strands form loops or appear as short, free-ending elements; their polymorphism suggests considerable lability, probably in connection with their assembly and disassembly. The existence of free-ending strands indicates that such structures can be used as attachment devices without being concomitantly involved in the formation of occluding zonules. In both types of junctions, the strands can be resolved into bars, approximately 80- 100nm long, frequently provided with terminal enlargements and intercalated particles which occur singly or in small clusters. These particles are morphologically similar to those present in communicating (gap) junctions. The mesothelium is also provided with isolate composite macular junctions. Throughout the mesothelium, the cleavage plane follows the outer contour of junctional strands and particles, suggesting that strand-to-strand interactions in the apposed membranes are weaker than interactions between each strand and underlying cytoplasmic structures. In their general geometry and cleavage characteristics, the mesothelial junctions resemble the junctions found in the venular endothelium

Book Reviews

Click on the link to view the book reviews.SAMJ 45(6

Witnessing the Growth of the Nearest Galaxy Cluster: Thermodynamics of the Virgo Cluster Outskirts

We present results from Suzaku Key Project observations of the Virgo Cluster, the nearest galaxy cluster to us, mapping its X-ray properties along four long `arms' extending beyond the virial radius. The entropy profiles along all four azimuths increase with radius, then level out beyond $0.5r_{200}$, while the average pressure at large radii exceeds Planck Sunyaev-Zel'dovich measurements. These results can be explained by enhanced gas density fluctuations (clumping) in the cluster's outskirts. Using a standard Navarro, Frenk and White (1997) model, we estimate a virial mass, radius, and concentration parameter of $M_{200}=1.05\pm0.02\times10^{14}$ M$_\odot$, $r_{200}=974.1\pm5.7$ kpc, and $c = 8.8 \pm0.2$, respectively. The inferred cumulative baryon fraction exceeds the cosmic mean at $r\sim r_{200}$ along the major axis, suggesting enhanced gas clumping possibly sourced by a candidate large-scale structure filament along the north-south direction. The Suzaku data reveal a large-scale sloshing pattern, with two new cold fronts detected at radii of 233 kpc and 280 kpc along the western and southern arms, respectively. Two high-temperature regions are also identified 1 Mpc towards the south and 605 kpc towards the west of M87, likely representing shocks associated with the ongoing cluster growth. Although systematic uncertainties in measuring the metallicity for low temperature plasma remain, the data at large radii appear consistent with a uniform metal distribution on scales of $\sim 90\times180$ kpc and larger, providing additional support for the early chemical enrichment scenario driven by galactic winds at redshifts of 2-3.Comment: submitted to MNRA

A uniform metallicity in the outskirts of massive, nearby galaxy clusters

Suzaku measurements of a homogeneous metal distribution of $Z\sim0.3$ Solar in the outskirts of the nearby Perseus cluster suggest that chemical elements were deposited and mixed into the intergalactic medium before clusters formed, likely over 10 billion years ago. A key prediction of this early enrichment scenario is that the intracluster medium in all massive clusters should be uniformly enriched to a similar level. Here, we confirm this prediction by determining the iron abundances in the outskirts ($r>0.25r_{200}$) of a sample of ten other nearby galaxy clusters observed with Suzaku for which robust measurements based on the Fe-K lines can be made. Across our sample the iron abundances are consistent with a constant value, $Z_{\rm Fe}=0.316\pm0.012$ Solar ($\chi^2=28.85$ for 25 degrees of freedom). This is remarkably similar to the measurements for the Perseus cluster of $Z_{\rm Fe}=0.314\pm0.012$ Solar, using the Solar abundance scale of Asplund et al. (2009).Comment: accepted for publication in MNRA

Central galaxy growth and feedback in the most massive nearby cool core cluster

We present multi-wavelength observations of the centre of RXCJ1504.1-0248 - the galaxy cluster with the most luminous and relatively nearby cool core at z~0.2. Although there are several galaxies within 100 kpc of the cluster core, only the brightest cluster galaxy (BCG), which lies at the peak of the X-ray emission, has blue colours and strong line-emission. Approximately 80 Msun/yr of intracluster gas is cooling below X-ray emitting temperatures, similar to the observed UV star formation rate of ~140 Msun/yr. Most star formation occurs in the core of the BCG and in a 42 kpc long filament of blue continuum, line emission, and X-ray emission, that extends southwest of the galaxy. The surrounding filamentary nebula is the most luminous around any observed BCG. The number of ionizing stars in the BCG is barely sufficient to ionize and heat the nebula, and the line ratios indicate an additional heat source is needed. This heat source can contribute to the H\alpha-deduced star formation rates (SFRs) in BCGs and therefore the derived SFRs should only be considered upper limits. AGN feedback can slow down the cooling flow to the observed mass deposition rate if the black hole accretion rate is of the order of 0.5 Msun/yr at 10% energy output efficiency. The average turbulent velocity of the nebula is vturb ~325 km/s which, if shared by the hot gas, limits the ratio of turbulent to thermal energy of the intracluster medium to less than 6%.Comment: 15 pages, 11 figures, MNRAS in press. Corrected typo in abstract

The X-ray coronae of the two brightest galaxies in the Coma cluster

We use deep Chandra X-ray Observatory observations to examine the coronae of the two brightest cluster galaxies in the Coma cluster of galaxies, NGC 4874 and NGC 4889. We find that NGC 4889 hosts a central depression in X-ray surface brightness consistent with a cavity or pair of cavities of radius 0.6 kpc. If the central cavity is associated with an AGN outburst and contains relativistic material, its enthalpy should be around 5x10^55 erg. The implied heating power of this cavity would be around an order of magnitude larger than the energy lost by X-ray emission. It would be the smallest and youngest known cavity in a brightest cluster galaxy and the lack of over pressuring implies heating is still gentle. In contrast, NGC 4874 does not show any evidence for cavities, although it hosts a well-known wide-angle-tail radio source which is visible outside the region occupied by the X-ray corona. These two galaxies show that AGN feedback can behave in varied ways in the same cluster environment.Comment: 11 pages, 11 figures, accepted by MNRA