Smart Child Portal: User Requirements For Children‟S Portal

Smart Child Company (SCC) akan beroperasi pada tahun 2011. The Smart Child Company (SCC) will operate in 2011

Genetic polymorphism of milk protein variants and their association studies with milk yield in Sahiwal cattle

The objective of this study was to determine the allele and genotype frequencies of genetic variants in five milk protein genes and estimate the effect of these variants on milk yield in Sahiwal cattle. Genotypes of five milk protein genes (alpha s1 casein, beta casein, kappa casein, alpha lactalbumin and beta lactoglobulin) were detected using SNaPshot genotyping method. All the five milk protein genes studied exhibited polymorphism with high allele frequencies of 0.51 for alpha s1casein C, 0.93 for beta casein A2, 0.92 for kappa casein A, 0.93 for alpha lactalbumin B and 0.91 for beta lactoglobulin B. Statistically significant differences (p > 0.05) were observed in kappa casein genotypes AA (AA) and AB (AC) that is, genotype AB had more milk yield in 1st lactation (422 kg) and 2nd lactation (612 kg), respectively. In conclusion, the AB genotype identified in kappa casein gene is associated with higher milk production therefore incorporation of AB and BB genotypes for kappa casein may help to improve the milk yield in Sahiwal cattle population of Pakistan. To the best of our knowledge, this is the first detailed study involving frequency distribution of genetic variants and their effects on milk yield in Bos indicus Sahiwal cattle of Pakistan.Keywords: Genetic variant, milk protein genes, Sahiwal cattleAfrican Journal of Biotechnology, Vol. 13(4), pp. 555-565, 22 January, 201

Knowledge and Attitude of Oral Health Professionals in the Management of Avulsed Teeth

Objectives: The purpose of this study is to assess the knowledge and to compare the attitude and management of tooth avulsion between the general dentist and the specialist all with dental interns.  Materials and Methods:16-point questionnaires have been developed to a similar study and have been validated by a group of specialist.  The first part of the survey contained demographic data. The second part consisted of eight questions checking dentists’ knowledge on the treatment of avulsed teeth. All in which took part in Saudi Arabia, Riyadh and covered 311 dentists. Data were analyzed with SPSS program version 21Results: 583 questionnaires have been distributed and a total of 311 were collected. Which consisted 53.34% of distributed surveys. Almost two-third (219) of the surveyed populations have never treated any patient with dental avulsion. Amongst those who had such experience, the majority treated at least one case (35.9%), there were also 22 (23.9%) dentist who treated more than 5 avulsed teeth. 25 of 311 dentist have never received education or training in the management of tooth avulsion. Conclusion: there is a need to familiarize oral health professions with the needed knowledge and management of avulsion through lectures and proper training. Keywords: Avulsion; knowledge; management; oral professional; denta

Patients with Chronic Kidney Disease and Their Quality of Life

This study aimed at exploring the assessment of Quality of Life (QOL) in patients with Chronic Kidney Disease (CKD), and aiming at assessing the QOL of patients with stages 1–5 Chronic Kidney Disease CKD on conservative treatment in order to identify a possible association between Quality Of Life QOL and progression of kidney insufficiency. The results were compared with those obtained for patients on hemodialysis. Sociodemographic, clinical and laboratory data were also evaluated. And the study concluded that research efforts have expanded significantly to determine the state of pediatric CKD patient HRQOL and the factors that impact HRQOL across all stages of CKD and all modalities of renal replacement therapy. Data from all studies suggest that children with a renal transplant fare better with respect to HRQOL than those receiving dialysis.

Efficacy of wheat-based biscuits fortified with microcapsules containing ferrous sulfate and potassium iodate or a new hydrogen-reduced elemental iron: a randomised, double-blind, controlled trial in Kuwaiti women

Adverse sensory changes prevent the addition of highly bioavailable ferrous sulfate (FeSO4) to most wheat flours. Poorly absorbable reduced Fe powders are commonly used. Encapsulation of FeSO4 can overcome these sensory changes, but the particle size of commercial compounds is too large to be used by flour mills. The first objective of the study was to measure the efficacy in wheat flour of two newly developed Fe compounds, an H-reduced Fe powder (NutraFine™ RS; North America Höganäs High Alloys LLC, Johnstown, PA, USA) and small particle-sized (40μm) encapsulated FeSO4. As a second objective, the microcapsules were evaluated as a vehicle for iodine fortification. A randomised, double-blind controlled intervention trial was conducted in Kuwaiti women (n 279; aged 18-35 years) with low body Fe stores (serum ferritin (SF) <25μg/l) randomly assigned to one of three groups (20mg Fe as NutraFine™ RS, 10mg Fe as encapsulated FeSO4 and 150μg iodine, or no fortification Fe) who consumed wheat-based biscuits 5d per week. At baseline and 22 weeks, Hb, SF, transferrin receptor, urinary iodine and body Fe stores were measured. Relative to control, mean SF in the encapsulated FeSO4 group increased by 88% (P<0·001) and body Fe stores increased from −0·96 to 2·24mg/kg body weight (P<0·001), while NutraFine™ RS did not significantly increase SF or body Fe stores. The median urinary iodine concentration increased from 140 to 213μg/l (P<0·01). NutraFine™ RS added at double the amount of Fe as FeSO4 was not efficacious in improving Fe status. The newly developed microcapsules were highly efficacious in improving both Fe stores and iodine statu

Evaluate the prevalence of CCP and RF antibodies as a marker for diagnosis and progression of Rheumatoid Arthritis disease and assess the prevalence of HCV in RA patients

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by the presence of autoantibodies like rheumatoid factor (RF). In the last few years, several other autoantibodies have been described of which anti-cyclic citrullinated peptide (CCP) antibody is the most specific. Chronic hepatitis C virus (HCV) has extrahepaticautoimmune properties and a variety of autoantibodies were found in patients with HCV. This study is conductedto evaluate the sensitivity and specificity of Anti-CCP in compare with RF in RA patients and assess their association with severity of the disease and evaluate if HCV have beenone of the infectious agent for rheumatoid arthritis.Sixty blood samples were collected from RA patients and twenty from both apparently healthy group and HCV patients. The serum from each subject was tested for anti- CCP, RF and anti HCV by enzyme- linked immunosorbent assay (ELISA). Estimation of erythrocyte sedimentation rate (ESR) by Westergreen' method was included in this study. The result indicated that anti-CCP postivity for RA patients sera (78.3%), (20%) for HCV patients and (0.0%) for healthy group, it showed highly significant differences in RA group in compare with control group (P<0.005).While the percentage of RF positive was (70%) for patients with rheumatoid arthritis with significant differences and 20% for patients with viral hepatitis type (c) with no significant differences in compare with control group (5%). Results also showed that (1.7%) of patients with rheumatoid arthritis showed positive result to HCV

Identification of absolute geometries of cis and trans molecular isomers by Coulomb Explosion Imaging

Citation: Ablikim, U., Bomme, C., Xiong, H., Savelyev, E., Obaid, R., Kaderiya, B., . . . Rolles, D. (2016). Identification of absolute geometries of cis and trans molecular isomers by Coulomb Explosion Imaging. Scientific Reports, 6, 8. doi:10.1038/srep38202An experimental route to identify and separate geometric isomers by means of coincident Coulomb explosion imaging is presented, allowing isomer-resolved photoionization studies on isomerically mixed samples. We demonstrate the technique on cis/trans 1,2-dibromoethene (C2H2Br2). The momentum correlation between the bromine ions in a three-body fragmentation process induced by bromine 3d inner-shell photoionization is used to identify the cis and trans structures of the isomers. The experimentally determined momentum correlations and the isomer-resolved fragment-ion kinetic energies are matched closely by a classical Coulomb explosion model

Time-resolved molecular dynamics of single and double hydrogen migration in ethanol

Being the lightest, most mobile atom that exists, hydrogen plays an important role in the chemistry of hydrocarbons, proteins and peptides and most biomolecules. Hydrogen can undergo transfer, exchange and migration processes, having considerable impact on the chemical behavior of these molecules. Although much has been learned about reaction dynamics involving one hydrogen atom, less is known about those processes where two or more hydrogen atoms participate. Here we show that single and double hydrogen migrations occurring in ethanol cations and dications take place within a few hundred fs to ps, using a 3D imaging and laser pump-probe technique. For double hydrogen migration, the hydrogens are not correlated, with the second hydrogen migration promoting the breakup of the C–O bond. The probability of double hydrogen migration is quite significant, suggesting that double hydrogen migration plays a more important role than generally assumed. The conclusions are supported by state-of-the-art molecular dynamics calculationsThis work was funded by the National Science Foundation under award No. 1700551, the MINECO projects FIS2016-77889-R and CTQ2016- 76061-P, ‘Severo Ochoa’ Programme for Centres of Excellence in R&D (SEV-2016-0686) and ‘María de Maeztu’ Programme for Units of Excellence in R&D (MDM-2014-0377). We acknowledge the generous allocation of computer time at the Centro de Computación Científica at the Universidad Autónoma de Madrid (CCC-UAM). S.D.-T. gratefully acknowledges the “Ramón y Cajal” program (RYC-2010-07019) of the Spanish Ministerio de Educación y Cienci