82 research outputs found

    The Technique for I–V Characteristic Measurements of MOSFETs from Output Stage of MOS ICs

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    Experimental technique for measurements of I–V characteristics of MOSFETs from output stage of MOS ICs is developed and demonstrated using Schmitt trigger array 1594TL2T

    Schematic Method of Estimation and Increase of Radiation Hardness of the Onboard Radio-electronic Equipment for Space Applications

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    Experimental and theoretical justification of a schematic method of estimation and increase of radiation hardness of the onboard radio-electronic equipment for space applications on the example of the standard circuit of the voltage follower combining the most widespread schematic decisions: differential stage, current mirror and emitter follower

    Methods and Results of Radiation Tests of a Digital-to-Analog Converter LTC1257

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    The methods and results of radiation tests of a digital-to-analog converter (DAC) LTC1257 is observed in this article

    The Methodology and Results of Radiation Tests of ADS 8320 Analog-to-Digital Converter

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    This article describes a technique ADC ADS8320 radiation tests, as well as circuitry measuring the transfer characteristic of the ADC and the results of tests conducted. It has been found that said ADCs did not show any parametric or functional failure when the absorbed doses to 50 krad (Si) at an intensity of irradiation of 8.5 F/sec passive electric mode

    The Application of Schematic Compensation Technique for Increasing of Radioelectronic Devices Reliability

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    The schematic method development of radiation degradation compensation of operating amplifiers’ input currents and offset voltages on basis of radiation-sensitive parameter degradation research of integral microcircuits and discrete transistors is presented and experimentally verified

    Gas phase characterization of the noncovalent quaternary structure of Cholera toxin and the Cholera toxin B subunit pentamer

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    Cholera toxin (CTx) is an AB5 cytotonic protein that has medical relevance in cholera and as a novel mucosal adjuvant. Here, we report an analysis of the noncovalent homopentameric complex of CTx B chain (CTx B5) using electrospray ionization triple quadrupole mass spectrometry and tandem mass spectrometry and the analysis of the noncovalent hexameric holotoxin usingelectrospray ionization time-of-flight mass spectrometry over a range of pH values that correlate with those encountered by this toxin after cellular uptake. We show that noncovalent interactions within the toxin assemblies were maintained under both acidic and neutral conditions in the gas phase. However, unlike the related Escherichia coli Shiga-like toxin B5 pentamer (SLTx B), the CTx B5 pentamer was stable at low pH, indicating that additional interactions must be present within the latter. Structural comparison of the CTx B monomer interface reveals an additional α-helix that is absent in the SLTx B monomer. In silico energy calculations support interactions between this helix and the adjacent monomer. These data provide insight into the apparent stabilization of CTx B relative to SLTx B
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