Spanish CLARIN K-Centre

Presentamos CLARIN Centro-K-español que forma parte de la infraestructura europea CLARIN, Common Language Resources and Technology Infrastructure, y cuyo objetivo es ofrecer los conocimientos y experiencia de los tres grupos que inicialmente lo componen en la utilización de tecnología para la investigación en humanidades y ciencias sociales.We introduce Spanish CLARIN Centre-K, a node of the European infrastructure CLARIN, Common Language Resources and Technology, whose objective is to share knowledge and experience of the three funding constituent groups for research in humanities and social sciences

Malignant Solitary Fibrous Tumour of the Breast Mimicking a Benign Tumor

Solitary fibrous tumour (SFT) of the breast is exceedingly uncommon. Radiological assessment usually shows benign features. We report on a case of malignant SFT of the breast, while emphasizing the need for additional immunostains to reach a definitive diagnosis. Standard treatment consists of lesion removal with adequate margins

SARS-CoV-2 T-cell response in COVID-19 convalescent patients with and without lung sequelae

A specific T-cell response persists in the majority of COVID-19 patients 6 months after hospital discharge. This response is more prominent in those who required critical care during the acute COVID-19 episode but is reduced in patients with lung sequelae

Helioseismic and neutrino data-driven reconstruction of solar properties

In this work, we use Bayesian inference to quantitatively reconstruct the solar properties most relevant to the solar composition problem using as inputs the information provided by helioseismic and solar neutrino data. In particular, we use a Gaussian process to model the functional shape of the opacity uncertainty to gain flexibility and become as free as possible from prejudice in this regard. With these tools we first readdress the statistical significance of the solar composition problem. Furthermore, starting from a composition unbiased set of standard solar models (SSMs) we are able to statistically select those with solar chemical composition and other solar inputs which better describe the helioseismic and neutrino observations. In particular, we are able to reconstruct the solar opacity profile in a data-driven fashion, independently of any reference opacity tables, obtaining a 4 per cent uncertainty at the base of the convective envelope and 0.8 per cent at the solar core. When systematic uncertainties are included, results are 7.5 per cent and 2 per cent, respectively. In addition, we find that the values of most of the other inputs of the SSMs required to better describe the helioseismic and neutrino data are in good agreement with those adopted as the standard priors, with the exception of the astrophysical factor S11 and the microscopic diffusion rates, for which data suggests a 1 per cent and 30 per cent reduction, respectively. As an output of the study we derive the corresponding data-driven predictions for the solar neutrino fluxes

Análisis de la imagen cromática del conjunto de 127 edificios históricos de la calle Didouche Mourad en Skikda (Argelia)

Las ciudades de la cuenca mediterránea tienen un pasado que se puede leer a través de sus tramas urbanas y de los edificios que se conservan. Aquellas con una larga historia se convierten en un palimpsesto sobre el que se superponen las distintas épocas y algunos edificios substituyen a los que han quedado obsoletos mientras otros evolucionan y son sometidos a rehabilitaciones o grandes transformaciones para dar respuesta a nuevas necesidades. Esta lógica transformación de la ciudad, a veces significa la pérdida de sus valores patrimoniales, más aún cuando se dan acontecimientos históricos que impulsan a modificar el aspecto de los edificios por motivos culturales o de identidad, relacionados por cambios de gobierno, de religión e incluso por la imposición de modas estéticas. Las fachadas de los edificios históricos son las que más sufren y a la vez mejor reflejan estas incidencias, lo que las convierte en interesantes documentos para el análisis y la investigación. La ciudad de Skikda está ubicada en la costa mediterránea de Argelia y es un buen ejemplo de ciudad con un pasado de más de 2000 años que ha sufrido distintos avatares hasta su consolidación actual como ciudad portuaria y con una intensa actividad social. La arteria principal de Skikda es la actual Rue Didouche Mourad, que atraviesa la ciudad de Norte a sur sobre la antigua vía de Philippeville a Constantine. El objetivo de esta presentación es mostrar una metodología de estudio, a partir de un análisis pluridisciplinar, del conjunto histórico de edificios que conforman la actual Rue Didouche Mourad, documentar científicamente los procesos de transformación de esta arteria y elaborar unas hipótesis de su herencia cromática. Toda la información se ha puesto a disposición de la administración local y de los profesionales encargados de intervenir en el patrimonio arquitectónico de la ciudad.Peer ReviewedPostprint (published version

Las mujeres en el mercado de trabajo de las tecnologías

El mercado laboral tecnológico, donde las mujeres son minoría, representa una oportunidad para el empleo en España. Este trabajo analiza los datos de la Encuesta de Población Activa (EPA) respecto a la población ocupada en el sector tecnológico. En primer lugar, se analiza la segregación de género de la población ocupada según sectores económicos y, en segundo lugar, las características de empleo de las mujeres ocupadas en el sector tecnológico. Los resultados indican que las mujeres disponen de buenas expectativas laborales en este sector, pero también indican que sufren un mayor riesgo de sobrecualificación, lo que sugiere la persistencia de factores de discriminación. Por último, las mujeres expresan mayor preocupación que sus colegas hombres respecto a las excesivas jornadas laborales, lo que plantea la necesidad de afrontar un cambio estructural en las organizaciones

Limited risk of Zika virus transmission by five Aedes albopictus populations from Spain

Background: Aedes albopictus, the Asian tiger mosquito, is an exotic invasive species in Europe. It has substantial public health relevance due to its potential role in transmitting several human pathogens. Out of the European countries, Spain has one of the highest risk levels of autochthonous arbovirus transmission due to both the high density of Ae. albopictus and the extensive tourist influx from vector-endemic areas. This study aims to investigate the susceptibility of five Ae. albopictus populations from mainland Spain and the Balearic Islands to a Brazilian Zika virus (ZIKV) strain. Methods: The F1 generation of each Ae. albopictus population was orally challenged with a ZIKV-infected blood meal (1.8 × 10 PFU/ml). At 7 and 14 days post-infection (dpi), mosquito bodies (thorax and abdomen) and heads were individually analysed through RT-qPCR to determine the infection rate (IR) and dissemination rate (DR), respectively. The saliva of infected mosquitoes was inoculated in Vero cells and the transmission rate was assessed by plaque assay or RT-qPCR on ∼33 individuals per population. Results: The IR and DR ranged between 12-88%, and 0-60%, respectively, suggesting that ZIKV is capable of crossing the midgut barrier. Remarkably, no infectious viral particle was found in saliva samples, indicating a low ability of ZIKV to overcome the salivary gland barrier. A subsequent assay revealed that a second non-infective blood meal 48 h after ZIKV exposure did not influence Ae. albopictus vector competence. Conclusions: The oral experimental ZIKV infections performed here indicate that Ae. albopictus from Spain become infected and disseminate the virus through the body but has a limited ability to transmit the Brazilian ZIKV strain through biting. Therefore, the results suggest a limited risk of autochthonous ZIKV transmission in Spain by Ae. albopictus

Lung Function sequelae in COVID-19 Patients 3 Months After Hospital Discharge

About 20% of patients infected by the SARS-CoV-2 virus develop Coronavirus Disease 2019 (COVID-19) pneumonia and require hospitalization.1 Some recent reports have shown that some of them may present lung function abnormalities at discharge, or soon afterwards.Here, we: (1) describe the presence and characteristics of lung function abnormalities 3 months after hospital discharge in a large prospective cohort of well characterized patients hospitalized because of COVID-19 in our institution; and, (2) explore potential clinical predictors these short-term lung function sequelae

Evaluation of a New Digital Automated Glycemic Pattern Detection Tool

Background: Blood glucose meters are reliable devices for data collection, providing electronic logs of historical data easier to interpret than handwritten logbooks. Automated tools to analyze these data are necessary to facilitate glucose pattern detection and support treatment adjustment. These tools emerge in a broad variety in a more or less nonevaluated manner. The aim of this study was to compare eDetecta, a new automated pattern detection tool, to nonautomated pattern analysis in terms of time investment, data interpretation, and clinical utility, with the overarching goal to identify early in development and implementation of tool areas of improvement and potential safety risks. Methods: Multicenter web-based evaluation in which 37 endocrinologists were asked to assess glycemic patterns of 4 real reports (2 continuous subcutaneous insulin infusion [CSII] and 2 multiple daily injection [MDI]). Endocrinologist and eDetecta analyses were compared on time spent to analyze each report and agreement on the presence or absence of defined patterns. Results: eDetecta module markedly reduced the time taken to analyze each case on the basis of the emminens eConecta reports (CSII: 18 min; MDI: 12.5), compared to the automatic eDetecta analysis. Agreement between endocrinologists and eDetecta varied depending on the patterns, with high level of agreement in patterns of glycemic variability. Further analysis of low level of agreement led to identifying areas where algorithms used could be improved to optimize trend pattern identification. Conclusion: eDetecta was a useful tool for glycemic pattern detection, helping clinicians to reduce time required to review emminens eConecta glycemic reports. No safety risks were identified during the study