Nueva fórmula magistral en forma de colutorio para lesiones dolorosas de la mucosa oral

Presentamos un nuevo colutorio como tratamiento tópico de úlceras orales benignas agudas, a base de lidocaína y clorhexidina en solución acuosa

Potenciales evocados cerebrales en el contexto de la investigación psicológica: una actualización

Event-related brain potentials (ERPS) are presented in the context of the psychological research. Firstly, aspects such as how un ERP is obtained, their characteristic features, the way in which they are classified, or their main advantages with respect to another type of measures usually used in Psychology, are presented. Then, two cognitive processes that have been extensively investigated with this technique are briejly reviewed, concretely, attention and language, and the recent research in the study of emotional processes is also commented. The main ERPs that have been used to study these psychological processes are discussed

Portal para la predicción económica y empresarial

L’objectiu d’aquest treball és presentar un resum de l’experiència docent de l’ensenyança a través de una plataforma virtual. Aquesta experiència es troba adscrita a un Projecte d’Innovació docent de la Universitat de Córdoba anomenat: Desarrollo de un Portal para el análisis de casos reales, realitzat per un grup de professors del Dpto. de Estadística, Econometría, I.O. y Organización de empresas, consistent en l’estudi de les Ciències Estadístiques i el desenvolupament, implementació i avaluació de les alternatives en la resolució de problemes econòmics i empresarials vinculat amb assignatures de grau i postgrau de la Llicenciatura en Administració i Direcció d’Empreses de la Universitat de Córdoba.The aim of this paper is to present a summary of the educational experience of the education in Business forecasting using a virtual platform. The development has been part of a project of educational innovation of the University of Cordova titled: Development of a Portal for the analysis of real cases in Business forecasting, realized by a research Group from the department of Statistics, Econometrics, and Business Organization, consisting of the study, implementation and evaluation of several alternatives in this field, oriented to the resolution of economic and managerial problems. It has been tested with under and postgraduate students in Business administration and economics at the University of Cordova.El objetivo de este trabajo es presentar un resumen de la experiencia docente de la enseñanza a través de una plataforma virtual. Dicha experiencia queda adscrita a un Proyecto de Innovación docente de la Universidad de Córdoba denominado: Desarrollo de un Portal para el análisis de casos reales, realizado por un grupo de profesores del Dpto. de Estadística, Econometría, I.O. y Organización de empresas, consistente en el estudio de las Ciencias Estadísticas y el desarrollo, implementación y evaluación de las alternativas en la resolución de problemas económicos y empresariales vinculado con asignaturas de grado y posgrado de la Licenciatura en Administración y Dirección de Empresas de la Universidad de Córdoba

Activation of nucleus accumbens NMDA receptors differentially affects appetitive or aversive taste learning and memory

Taste memory depends on motivational and post-ingestional consequences; thus, it can be aversive (e.g., conditioned taste aversion, CTA) if a novel, palatable taste is paired with visceral malaise, or it can be appetitive if no intoxication appears after novel taste consumption, and a taste preference is developed.The nucleus accumbens (NAc) plays a role in hedonic reactivity to taste stimuli, and recent findings suggest that reward and aversion are differentially encoded by the activity of NAc neurons. The present study examined whether the requirement for N-methyl-D-aspartate (NMDA) receptors in the NAc core during rewarding appetitive taste learning differs from that during aversive taste conditioning, as well as during retrieval of appetitive vs. aversive taste memory, using the taste preference or CTA model, respectively. Bilateral infusions of NMDA (1 μg/μl, 0.5 μl) into the NAc core were performed before acquisition or before retrieval of taste preference or CTA. Activation of NMDA receptors before taste preference training or CTA acquisition did not alter memory formation. Furthermore, NMDA injections before aversive taste retrieval had no effect on taste memory; however, 24 h later, CTA extinction was significantly delayed. Also, NMDA injections, made before familiar appetitive memory retrieval, interrupted the development of taste preference and produced a preference delay 24 h later. These results suggest that memory formation for a novel taste produces neurochemical changes in the NAc core that have differential requirements for NMDA receptors during retrieval of appetitive or aversive memory

El CReSA estudia millorar la detecció de virus en aus

La Influença Aviària (IA) és una malaltia molt contagiosa, causada per un virus del gènere Influenzavirus tipus A, que pot arribar a causar elevada mortalitat en aus de producció. El Centre de Recerca en Sanitat Animal de la UAB estudia, entre altres aspectes, la detecció i prevalença d'aquest virus. Enguany treballa en la posada al punt d'una nova tècnica més fiable que la convencional.La Influenza Aviar (IA) es una enfermedad muy contagiosa, causada por un virus del género Influenzavirus tipo A, que puede llegar a causar elevada mortalidad en aves de producción. El Centre de Recerca en Sanitat Animal de la UAB estudia, entre otros aspectos, la detección y prevalencia de este virus. Este año trabaja en la puesta a punto de una nueva técnica más fiable que la convencional

Authentication of paprika using HPLC-UV fingerprints

In this work we combine simple extraction and HPLC-UV methodologies with chemometric pattern-recognition strategies in order to obtain characteristic fingerprints of phenolic compounds that allow the authentication of paprika samples. To illustrate the potential of the proposed approach, two different adulteration scenarios were considered, namely adulteration of paprika based on its type (sweet, bittersweet and spicy) as well as on its region (Murcia, la Vera and Czech Republic). Upon preparation of a proper set of samples, those were analysed using a C18 reversed-phase column and registered chromatograms were then compressed employing fast Fourier transform (FFT) to reduce the large dimensionality of the data set, while preserving all relevant features. Next, data were analysed using linear discriminant analysis (LDA) for the qualitative discrimination of adulterated samples, or by partial least-squares regression (PLS) modelling to quantitatively assess the adulteration degree

Polymorphisms of the WNT10B Gene, Bone Mineral Density, and Fractures in Postmenopausal Women

Producción CientíficaWnt ligands are important regulators of skeletal homeostasis. Wnt10B tends to stimulate the differentiation of common mesenchymal precursors toward the osteoblastic lineage, while inhibiting adipocytic differentiation. Hence, we decided to explore the association of WNT10B allelic variants with bone mineral density and osteoporotic fractures. A set of tag SNPs capturing most common variations of the WNT10B gene was genotyped in 1438 Caucasian postmenopausal women, including 146 with vertebral fractures and 432 with hip fractures. We found no association between single SNPs and spine or hip bone mineral density (BMD). In the multilocus analysis, some haplotypes showed a slight association with spine BMD (P = 0.03), but it was not significant after multiple-test correction. There was no association between genotype and vertebral or hip fractures. Transcripts of WNT10B and other Wnt ligands were detected in human bone samples by real-time PCR. However, there was no relationship between genotype and RNA abundance. Thus, WNT10B is expressed in the bone microenvironment and may be an important regulator of osteoblastogenesis, but we have not found evidence for a robust association of common WNT10B gene allelic variants with either BMD or fractures in postmenopausal women

Determination of HPLC-UV fingerprints of Spanish paprika (Capsicum annuum L.) for its classification by linear discriminant analysis

The development of a simple HPLC-UV method towards the evaluation of Spanish paprika' phenolic profile and their discrimination based on the former is reported herein. The approach is based on C18 reversed-phase chromatography to generate characteristic fingerprints, in combination with linear discriminant analysis (LDA) to achieve their classification. To this aim, chromatographic conditions were optimized so as to achieve the separation of major phenolic compounds already identified in paprika. Paprika samples were subjected to a sample extraction stage by sonication and centrifugation; extracting procedure and conditions were optimized to maximize the generation of enough discriminant fingerprints. Finally, chromatograms were baseline corrected, compressed employing fast Fourier transform (FFT), and then analyzed by means of principal component analysis (PCA) and LDA to carry out the classification of paprika samples. Under the developed procedure, a total of 96 paprika samples were analyzed, achieving a classification rate of 100% for the test subset (n=25)

Detection of Porcine Circovirus 3 in Wildlife Species in Spain

Porcine circovirus 3 (PCV-3) is the third member of the family Circoviridae, genus Circovirus, able to infect swine. A high prevalence of viral DNA has been recorded in wild boars. Recently, PCV-3 DNA was identified in Italian wild ruminants. Based on these previous results, this study assessed the frequency of PCV-3 DNA detection in free-ranging ruminants and Lagomorpha species in Spain. In addition, the genetic characterization of the PCV-3 PCR-positive samples was performed. A total of 801 serum samples, including red deer (Cervus elaphus, [CE]; n = 108), roe deer (Capreolus capreolus, [CC]; n = 87), Pyrenean chamois (Rupicapra pyrenaica, [RP]; n = 133), Iberian ibex (Capra pyrenaica, [CP]; n = 92), mouflon (Ovis aries, [OA]; n = 91), fallow deer (Dama dama, [DD]; n = 104), European rabbit (Oryctolagus cuniculus, [OC]; n = 101), and European hare (Lepus europaeus, [LE]; n = 85) from Catalonia (northeast Spain) were tested by conventional polymerase chain reaction (PCR) and, when positive, sequenced. Overall, PCV-3 DNA was found in three out of 801 analyzed sera (0.37%) corresponding to one red deer (1/108, 0.9%), one mouflon (1/91, 1.1%), and one fallow deer (1/104, 0.96%). None of the samples collected from Lagomorpha species resulted PCR positive. The partial genome sequences detected in positive samples displayed high identity with some PCV-3 sequences detected in wild boars and domestic pigs (99.7% and 100%, respectively). In conclusion, the present study indicated that free-ranging ruminant and Lagomorpha species are not relevant in the epidemiology of PCV-3 in Spain.info:eu-repo/semantics/publishedVersio