1,080 research outputs found
Atlas Data-Challenge 1 on NorduGrid
The first LHC application ever to be executed in a computational Grid
environment is the so-called ATLAS Data-Challenge 1, more specifically, the
part assigned to the Scandinavian members of the ATLAS Collaboration. Taking
advantage of the NorduGrid testbed and tools, physicists from Denmark, Norway
and Sweden were able to participate in the overall exercise starting in July
2002 and continuing through the rest of 2002 and the first part of 2003 using
solely the NorduGrid environment. This allowed to distribute input data over a
wide area, and rely on the NorduGrid resource discovery mechanism to find an
optimal cluster for job submission. During the whole Data-Challenge 1, more
than 2 TB of input data was processed and more than 2.5 TB of output data was
produced by more than 4750 Grid jobs.Comment: Talk from the 2003 Computing in High Energy Physics and Nuclear
Physics (CHEP03), La Jolla, Ca, USA, March 2003, 7 pages, 3 ps figure
High Voltage Powerline Injury Studies
Current pathways and reconstructions of human injury after contact with distribution powerlines are not well understood. The impedance, currents, and modes of tissue destruction are rarely known. Eight anesthetized hogs, weighing 68 to 90 kg, were used in studies with potentials ranging from 2,100 to 14,400 volts. Electrical contact was made between the hindlimbs, from the hindlimb to forelimb, and over other regions of the body. Currents from 4 to 70 amperes rms and impedances ranging from 130 to 477 ohms were measured. Phase angles up to 40° were observed. Copyright Š 1981 by The Institute of Electrical and Electronics Engineers, Inc
Psychiatric symptoms in COVID-19-positive individuals in the general population: Trajectories of depression, anxiety, and insomnia
The present study investigates differences in the trajectories of anxiety, depression, and sleep problems among infected versus non-infected case-controlled individuals. Patients who tested positive for COVID-19 were selected from a representative sample in Norway (N > 10,000). In total, 126 of these individuals were infected during the project period, and this group was analyzed at T5 (May 2021). Of these positive cases, those who had completed both PHQ-9 and GAD-7 at all three measurement points were selected for longitudinal analysis using multilevel modeling. There was a significant difference at T5 between those who had tested positive for COVID-19 and matched controls. Anxiety and depression were reduced among those who tested positive, but there were no differences in trajectory when compared to matched controls. Limitations include the use of self-report measures and the assessment of symptoms at a time when strict virus mitigation protocols were in place. The present findings indicate that individuals who test positive for COVID-19 exhibit higher levels of depressive symptoms after restrictions are lifted. However, comparison of anxiety and depression symptom trajectories with matched controls reveals that both groups exhibited stable or slightly decreased symptoms.publishedVersio
Monitoring Of CO2 Leakage Using High-Resolution 3D Seismic Data â Examples From Snøhvit, Vestnesa Ridge And The Western Barents Sea
Source at https://doi.org/10.3997/2214-4609.201802965.Injection of CO2 in subsurface reservoirs may cause overburden deformation and CO2 leakage. The aim of this study is to apply technologies for detection and monitoring of CO2 leakage and deformation above the injection reservoirs. The examples of this study include data from the Vestnesa Ridge natural seep site, the Snøhvit gas field and CO2 storage site region, and the Gemini North gas reservoir. Reprocessing of existing 3D high-resolution seismic data allows resolving features with a vertical and lateral resolution down to c. 1 m and c. 5 m respectively. The current acquisition systems could be modified to image structures down to one meter in both the vertical and horizontal directions. We suggest a monitoring workflow that includes baseline and time-lapse acquisition of highresolution 3D seismic data, integrated with geochemical, geophysical, and geotechnical seabed core and watercolumn measurements. The outcome of such a workflow can deliver reliable quantitative property volumes of the subsurface and will be able to image meter-sized anomalies of fluid leakage and deformation in the overburden
Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer.
BACKGROUND: The aim of this study was to investigate the value of the cyclin D1 isoforms D1a and D1b as prognostic factors and their relevance as predictors of response to adjuvant chemotherapy with 5-fluorouracil and levamisole (5-FU/LEV) in colorectal cancer (CRC).
METHODS: Protein expression of nuclear cyclin D1a and D1b was assessed by immunohistochemistry in 335 CRC patients treated with surgery alone or with adjuvant therapy using 5-FU/LEV. The prognostic and predictive value of these two molecular markers and clinicopathological factors were evaluated statistically in univariate and multivariate survival analyses.
RESULTS: Neither cyclin D1a nor D1b showed any prognostic value in CRC or colon cancer patients. However, high cyclin D1a predicted benefit from adjuvant therapy measured in 5-year relapse-free survival (RFS) and CRC-specific survival (CSS) compared to surgery alone in colon cancer (P=0.012 and P=0.038, respectively) and especially in colon cancer stage III patients (P=0.005 and P=0.019, respectively) in univariate analyses. An interaction between treatment group and cyclin D1a could be shown for RFS (P=0.004) and CSS (P=0.025) in multivariate analysis.
CONCLUSION: Our study identifies high cyclin D1a protein expression as a positive predictive factor for the benefit of adjuvant 5-FU/LEV treatment in colon cancer, particularly in stage III colon cancer
Pre-breakup magmatism on the Vøring margin: Insight from new sub-basalt imaging and results from Ocean Drilling program hole 642E
Highlights
⢠Sub-basalt imaging improvement on the Vøring Margin
⢠Definition of a new seismic facies unit: the Lower Series Flows
⢠Significant organic carbon content within the melting crustal segment
⢠Apectodinium augustum marker for the PETM is reworked into the Lower Series Flows
⢠The Lower Series Flows, early Eocene in age, predate the Vøring Margin breakup
Abstract
Improvements in sub-basalt imaging combined with petrological and geochemical observations from the Ocean Drilling Program (ODP) Hole 642E core provide new constraints on the initial breakup processes at the Vøring Margin. New and reprocessed high quality seismic data allow us to identify a new seismic facies unit which we define as the Lower Series Flows. This facies unit is seismically characterized by wavy to continuous subparallel reflections with an internal disrupted and hummocky shape. Drilled lithologies, which we correlate to this facies unit, have been interpreted as subaqueous flows extruding and intruding into wet sediments. Locally, the top boundary of this facies unit is defined as a negative in polarity reflection, and referred as the K-Reflection. This reflection can be correlated with the spatial extent of pyroclastic deposits, emplaced during transitional shallow marine to subaerial volcanic activities during the rift to drift transition. The drilled Lower Series Flows consist of peraluminous, cordierite bearing peperitic basaltic andesitic to dacitic flows interbedded with thick volcano-sedimentary deposits and intruded sills. The peraluminous geochemistry combined with available C (from calcite which fills vesicles and fractures), Sr, Nd, and Pb isotopes data point towards upper crustal rock-mantle magma interactions with a significant contribution of organic carbon rich pelagic sedimentary material during crustal anatexis. From biostratigraphic analyses, Apectodinium augustum was found in the The Lower Series Flows. This species is a marker for the Paleocene â Eocene Thermal Maximum (PETM). However, the absence of very low carbon isotope values (from bulk organic matter), that characterize the PETM, imply that A.augustum was reworked into the early Eocene sediments of this facies unit which predate the breakup time of the Vøring Margin.
Finally, a plausible conceptual emplacement model for the Lower Series Flows facies unit is proposed. This model comprises several stages: (1) the emplacement of subaqueous peperitic basaltic andesitic flows intruding and/or extruding wet sediments; (2) a subaerial to shallow marine volcanism and extrusion of dacitic flows; (3) a proto-breakup phase with intense shallow marine to subaerial explosive volcanism responsible for pyroclastic flow deposits which can be correlated with the seismic K-Reflection and (4) the main breakup stage with intense transitional tholeiitic MORB-type volcanism and large subsidence concomitant with the buildup of the Seaward Dipping Reflector wedge
A Comparison of Components of Written Expression Abilities in Learning Disabled and Non-Learning Disabled Students at Three Grade Levels
Although written language plays a critical role in academic success, little empirical evidence exists on the normal development of processes involved in producing written products. Even less is known about the writing performance of LD children. This study empirically compared the written products of LD and normal students at three grade levels on The Test of Written Language. Results showed that LD subjects scored significantly lower than normal subjects on most written expression abilities, especially in the mechanical tasks of spelling, punctuation, and word usage.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
The FLT3 ligand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL) 11, IL-12, and other hematopoietic growth factors.
Investigative Interviews with Victims of Child Sexual Abuse: The Relationship between Question Type and Investigation Relevant Information
Breakup volcanism and plate tectonics in the NW Atlantic
The seismic, magnetic, and gravity data presented in this study were provided by TGS. Seismic interpretation was done using HS Kingdom software. Grid interpolations and map compilations were established using Geosoft Oasis Montaj and ArcGis softwares. We would like thank Craig Magee, Alexander Lewis Peace, the Editor and the Associated Editor for helpful comments and guidance that improved the paper. We acknowledge the support from the Research Council of Norway through its Center of Excellence funding scheme, project 223272 (CEED).Peer reviewedPostprin
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