Coleophora sirella Tabell & Mutanen, sp. n. from Finland (Lepidoptera: Coleophoridae)

 Coleophora sirella Tabell & Mutanen, sp. n. from Finland is described as new. The species resemblesmost closely C. glitzella O. Hofmann, 1869, C. murinella Tengström, 1848 and C. juncicolella Stainton, 1851 but has diagnostic differences in its life history, external appearance, genitalmorphology as well as DNA barcode. The new species feeds on Empetrum nigrum L. Adultmale and female, their genitalia as well as larval case are illustrated, and the known distribution range is given.DNAbarcodes are provided for the new species and its closestEuropean relatives

The role of local biodiversity in meeting nutritional requirements for complementary foods of infants and young children, Southern Benin

The mothers/care-givers, and the communities in general, will benefit from locally adapted information and knowledge on how to improve diets making the best use of the locally available biodiversity. Better knowledge and improved complementary feeding practices will contribute to better nutritional status of children and thus healthier and more productive communities

Joensuun kauppahalli

Tiivistelmä. Diplomityöni on suunnitelmapainotteinen työ, jossa esitän oman ehdotukseni Joensuun uudeksi kauppahalliksi. Joensuun edellinen kauppahalli purettiin torin etelälaidalta vuonna 2016. Purkamispäätöksestä lähtien olen seurannut keskusteluja siitä, tuleeko Joensuun torilla olemaan tulevaisuudessa kauppahallia vai ei. Olen itse Joensuusta kotoisin ja asunut siellä valtaosan elämästäni. Oma kiinnostukseni ja hankkeen ajankohtaisuus johti minut valitsemaan kyseisen aiheen diplomityökseni. Työ perustuu todelliseen tulevaan hankkeeseen, mutta se on tehty täysin riippumattomasti muista tahoista. Diplomityöni koostuu kirjallisesta selostusosasta ja kauppahallin suunnitelmasta. Kirjallisessa osassa käyn läpi yleisesti Suomen kauppahallien historiaa ja pohdin kauppahallien merkitystä kaupungeille ja sen asukkaille. Keskityn eritysesti Joensuun vanhoihin kauppahalleihin, joita on ollut kaiken kaikkiaan kaksi. Teen myös tilannekatsauksen siitä, mitä Joensuun torilla on lähivuosina tapahtunut ja missä vaiheessa kauppahallihanke on. Toisessa osassa esittelen kauppahallisuunnitelmani. Esitän suunnitelmassani ideoita, kuinka kauppahallin sijoituspaikan tuomia haasteita voisi ratkaista, sekä uudenlaisen kauppahallikonseptin, jossa kauppahalli koostuu kahdesta erillisestä palveluiltaan eriävästä osasta. Tämän ansiosta kauppahallin palveluaikaa voidaan jakaa portaittaisesti ja rakennus pysyy aktiivisena varhaisesta aamusta myöhäiseen iltaan saakka. Suunnitelmassa olen pyrkinyt huomioimaan Joensuun historian, torin alueen nykytilan, sen ympäristön sekä kauppahalli toiminnan nykytarpeet.Joensuu market hall. Abstract. My master’s thesis is a design oriented work, where I present my proposal for a new market hall to city of Joensuu. The previous market hall was demolished from the south side of the market square in 2016. Since then I have followed the discussions on whether ther will be market hall or not in Joensuu market place in the future. I am from Joensuu and have lived there most of my life. My own interest and the topicality of the project led me to choose this topic for my thesis. The work is based on a real future project, but it has been done in complitely independence from others. My thesis consists of a written commentary and a design of the market hall. In the written part I will go over the history of Finnish market halls and discuss their importance for the cities and their inhabitants. I focus especially on the two old market halls of Joensuu. I also review what has happened in the Joensuu Marketplace in the past few years and what is the current state of it. In the second part, I will present my market hall design. I present ideas on how to solve the challenges posed by the location of the market hall and a new concept for the market hall, where it is divided in two distinct parts. This allows the hall’s service hours to be staggered and the building to remain active from early morning until late at night. In the design I have tried to take into account the history of Joensuu, ​​the current state of the square area, as well as modern needs of the contemporary market hall

No difference in platelet activation or inflammation markers after diets rich or poor in vegetables, berries and apple in healthy subjects

Background: High intake of vegetables and fruits is associated with decreased risk of coronary heart disease. Part of these cardioprotective effects may be mediated via the antithrombotic effects of compounds found in vegetables and fruits, such as flavonoids. Aim of the study: To study the effects of high and low intake of vegetables, berries and apple on platelet function and inflammatory markers. Methods: The study was a randomised, controlled parallel human dietary intervention with healthy female and male volunteers (n = 77, 19–52 y). Nineteen healthy volunteers served as controls. The volunteers consumed one of four strictly controlled isocaloric 6-week diets containing either 810 or 196 g/10 MJ of vegetables, berries and apple and rich either in linoleic acid (11% of energy, en%) or oleic acid (12 en%). Blood and three 24-hour urine samples were collected at the beginning and at the end of the study period for analyses of various markers of platelet function and inflammation. Results: No differences between the treatment groups were seen in platelet count or volume, markers of platelet activation (ex vivo aggregation to ADP and thrombin receptor activating peptide, protein kinase C activity, urinary 2,3-dinor-thromboxane B2 excretion, plasma P-selectin), plasma intercellular adhesion molecule-1, sensitive C-reactive protein, or antiphospholipid antibodies. Conclusions: The results indicate that in healthy volunteers 6-week diets differing markedly in the amounts of vegetables, berries and apple do not differ in their effects on platelets or inflammation.Peer reviewe

Systematics and biology of some species of Micrurapteryx Spuler (Lepidoptera, Gracillariidae) from the Holarctic Region, with re-description of M. caraganella (Hering) from Siberia

During a DNA barcoding campaign of leaf-mining insects from Siberia, a genetically divergent lineage of a gracillariid belonging to the genus Micrurapteryx was discovered, whose larvae developed on Caragana Fabr. and Medicago L. (Fabaceae). Specimens from Siberia showed similar external morphology to the Palearctic Micrurapteryx gradatella and the Nearctic Parectopa occulta but differed in male genitalia, DNA barcodes, and nuclear genes histone H3 and 28S. Members of this lineage are re-described here as Micrurapteryx caraganella (Hering, 1957), comb. n., an available name published with only a brief description of its larva and leaf mine. Micrurapteryx caraganella is widely distributed throughout Siberia, from Tyumen oblast in the West to Transbaikalia in the East. Occasionally it may severely affect its main host, Caragana arborescens Lam. This species has been confused in the past with Micrurapreryx gradatella in Siberia, but field observations confirm that M. gradatella exists in Siberia and is sympatric with M. caraganella, at least in the Krasnoyarsk region, where it feeds on different host plants (Vicia amoena Fisch. and Vicia sp.). In addition, based on both morphological and molecular evidence as well as examination of type specimens, the North American Parectopa occulta Braun, 1922 and Parectopa albicostella Braun, 1925 are transferred to Micrurapteryx as M. occulta (Braun, 1922), comb. n. with albicostella as its junior synonym (syn. n.). Characters used to distinguish Micrurapteryx from Parectopa are presented and illustrated. These findings provide another example of the potential of DNA barcoding to reveal overlooked species and illuminate nomenclatural problems

EEG Artifact Removal in TMS Studies of Cortical Speech Areas

The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) is commonly applied for studying the effective connectivity of neuronal circuits. The stimulation excites neurons, and the resulting TMS-evoked potentials (TEPs) are recorded with EEG. A serious obstacle in this method is the generation of large muscle artifacts from scalp muscles, especially when frontolateral and temporoparietal, such as speech, areas are stimulated. Here, TMS–EEG data were processed with the signal-space projection and source-informed reconstruction (SSP–SIR) artifact-removal methods to suppress these artifacts. SSP–SIR suppressed muscle artifacts according to the difference in frequency contents of neuronal signals and muscle activity. The effectiveness of SSP–SIR in rejecting muscle artifacts and the degree of excessive attenuation of brain EEG signals were investigated by comparing the processed versions of the recorded TMS–EEG data with simulated data. The calculated individual lead-field matrix describing how the brain signals spread on the cortex were used as simulated data. We conclude that SSP–SIR was effective in suppressing artifacts also when frontolateral and temporoparietal cortical sites were stimulated, but it may have suppressed also the brain signals near the stimulation site. Effective connectivity originating from the speech-related areas may be studied even when speech areas are stimulated at least on the contralateral hemisphere where the signals were not suppressed that much.Peer reviewe

Coil optimisation for transcranial magnetic stimulation in realistic head geometry

Background: Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. Objective: To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape. Methods: We derive a semi-analytical integration scheme for computing the magnetic field energy of an arbitrary surface current distribution, compute the electric field induced by this distribution with a boundary element method, and optimise a TMS coil for focal stimulation. Additionally, we introduce a method for manufacturing such a coil by using Litz wire and a coil former machined from polyvinyl chloride. Results: We designed, manufactured, and validated an optimised TMS coil and applied it to brain stimulation. Our simulations indicate that this coil requires less than half the power of a commercial figure-of-eight coil, with a 41% reduction due to the optimised winding geometry and a partial contribution due to our thinner coil former and reduced conductor height. With the optimised coil, the resting motor threshold of abductor pollicis brevis was reached with the capacitor voltage below 600 V and peak current below 3000 A. Conclusion: The described method allows designing practical TMS coils that have considerably higher efficiency than conventional figure-of-eight coils. (C) 2017 Elsevier Inc. All rights reserved.Peer reviewe

A comparative cohort study of Duhamel and Endorectal Pullthrough for Hirschsprung's Disease

Background: There are limited data available to compare outcomes between surgical approaches for Hirschsprung’s disease. Duhamel and endorectal pull-through (ERPT) are two of the most common procedures performed worldwide. // Methods: Objective outcomes were compared between contemporary cohorts (aged 4–32 years) after Duhamel or ERPT using case–control methodology. Data were collected using prospectively administered standardized questionnaires on bowel and bladder function and quality of life (Pediatric Quality of Life Inventory, Short form 36 and Gastrointestinal Quality of Life Index). Patients were compared in two age groups (18 years and younger and older than 18 years) and reference made to normative control data. Multivariable analysis explored factors associated with poor outcomes. // Results: Cohorts were well matched by demographics, disease characteristics and incidence of postoperative complications (120 patients who underwent Duhamel versus 57 patients who had ERPT). Bowel function scores were similar between groups. Patients who underwent Duhamel demonstrated worse constipation and inferior faecal awareness scores (P < 0.01 for both age groups). Recurrent postoperative enterocolitis was significantly more common after ERPT (34 versus 6 per cent; odds ratio 15.56 (95 per cent c.i. 6.19 to 39.24; P < 0.0001)). On multivariable analysis, poor bowel outcome was the only factor significantly associated with poor urinary outcome (adjusted odds ratio 6.66 (95 per cent c.i. 1.74 to 25.50; P = 0.006)) and was significantly associated with markedly reduced quality of life (QoL) in all instruments used (P < 0.001 for all). There were no associations between QoL measures and pull-through technique. // Conclusion: Outcomes from Duhamel and ERPT are good in the majority of cases, with comparable bowel function scores. Constipation and impaired faecal awareness were more prevalent after Duhamel, with differences sustained in adulthood. Recurrent enterocolitis was significantly more prevalent after ERPT. Clustering of poor QoL and poor functional outcomes were observed in both cohorts, with seemingly little effect by choice of surgical procedure in terms of QoL

Complementary feeding practices among children under two years old In West Africa: A review

The burden of child malnutrition is still high in West African countries with 19.2 million stunted children and increases rapidly during the weaning period. This has been attributed to inappropriate complementary feeding practices. To our knowledge, few studies have tried to review the state of complementary feeding in the sub-region. This review aimed to provide an overview of current complementary feeding practices in West Africa in order to identify issues that should be targeted for ensuring optimal infant and young child nutrition. Articles and reports published from 2006 to 2016 were selected and reviewed. All documents were accessed through PubMed, Google scholar, and FreeFullPDF databases. Relevant and current documents focused on infant and young child (IYC) feeding from World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) were identified by using electronic searches via the Google platform. Complementary feeding practices are suboptimal in West Africa compared to the Northern Africa. Porridges and family dishes are the two main categories of complementary foods given to children and there are nutritionally inadequate. Enriched flours have been developed by using local diversity of food resources and improved food process like dehulling, fermentation, germination, malting, but their use remains low. Socio-economic, cultural and geographical factors were the determinants influencing IYC feeding practices at mother and household levels. Besides food availability, social, cultural, economic and geographic determinants were interrelated in a complex way to affect child feeding practices. This paper contributes to a much-needed evidence-based focus on the state of complementary feeding practices. As a key component to child survival, the improvement of complementary feeding has been shown to be the most effective in enhancing child growth and reducing stunting. Stakeholders such as policy and decision-makers, development partners, the private sector, and Non-Governmental Organizations should develop strategies for making enriched flours and nutritionally dense foods more accessible and affordable. Nutritional interventions should emphasize the promotion of adequate complementary feeding practices including feeding frequency, quality and quantity of diet and food safety in order to reduce malnutrition. Ongoing national plans and strategies for optimal IYC feeding should be encouraged to reduce child malnutrition. © 2018, African Scholarly Science Communications Trust (ASSCAT).Peer reviewe

Information dropout patterns in restriction site associated DNA phylogenomics and a comparison with multilocus Sanger data in a species-rich moth genus

A rapid shift from traditional Sanger sequencing-based molecular methods to the phylogenomic approach with large numbers of loci is underway. Among phylogenomic methods, restriction site associated DNA (RAD) sequencing approaches have gained much attention as they enable rapid generation of up to thousands of loci randomly scattered across the genome and are suitable for nonmodel species. RAD data sets however suffer from large amounts of missing data and rapid locus dropout along with decreasing relatedness among taxa. The relationship between locus dropout and the amount of phylogenetic information retained in the data has remained largely uninvestigated. Similarly, phylogenetic hypotheses based on RAD have rarely been compared with phylogenetic hypotheses based on multilocus Sanger sequencing, even less so using exactly the same species and specimens. We compared the Sanger-based phylogenetic hypothesis (8 loci; 6172 bp) of 32 species of the diverse moth genus Eupithecia (Lepidoptera, Geometridae) to that based on double-digest RAD sequencing (3256 loci; 726,658 bp). We observed that topologies were largely congruent, with some notable exceptions that we discuss. The locus dropout effect was strong. We demonstrate that number of loci is not a precise measure of phylogenetic information since the number of single-nucleotide polymorphisms (SNPs) may remain low at very shallow phylogenetic levels despite large numbers of loci. As we hypothesize, the number of SNPs and parsimony informative SNPs (PIS) is low at shallow phylogenetic levels, peaks at intermediate levels and, thereafter, declines again at the deepest levels as a result of decay of available loci. Similarly, we demonstrate with empirical data that the locus dropout affects the type of loci retained, the loci found in many species tending to show lower interspecific distances than those shared among fewer species. We also examine the effects of the numbers of loci, SNPs, and PIS on nodal bootstrap support, but could not demonstrate with our data our expectation of a positive correlation between them. We conclude that RAD methods provide a powerful tool for phylogenomics at an intermediate phylogenetic level as indicated by its broad congruence with an eight-gene Sanger data set in a genus of moths. When assessing the quality of the data for phylogenetic inference, the focus should be on the distribution and number of SNPs and PIS rather than on loci.Peer reviewe