391 research outputs found
Exploring Patterns in Student Dialogue While Using a Digital Platform Designed to Support Online Inquiry
Online inquiry, or using the Internet to generate questions and then search for, analyse, and synthesise information about these questions, is an essential part of digital literacy. However, processes involved in online inquiry are substantially complex. Prior research suggests that digital platforms can scaffold online inquiry processes. Moreover, the value of scaffolding dialogue in collaborative activities has been shown to enhance critical thinking, an important part of online inquiry. This study investigates whether the use of digital platforms designed to scaffold online inquiry can support productive dialogue when used collaboratively. Data from four pairs of high school students was collected as they worked together using both the digital platform and multiple online sources outside the platform to complete an online inquiry task. Each pair’s interactions were analysed to investigate whether features of the digital platform prompted productive dialogue. In line with research suggesting the use of academic language influences content understanding, each pair’s use of certain academic terms related to the task and digital platform’s interface were also statistically examined. Results suggested that most productive dialogue occurred when using the digital platform. Additionally, two of the four academic terms investigated occurred more often in talk while interacting with the digital platform, compared to talk when on another website. A comparison of timelines associated with these terms offered examples of how initially they were said exclusively while on the tool, and then progressed towards independent use
‘A double-edged sword. This is powerful but it could be used destructively’: Perspectives of early career education researchers on learning analytics
Learning analytics has been increasingly outlined as a powerful tool for measuring, analysing, and predicting learning experiences and behaviours. The rising use of learning analytics means that many educational researchers now require new ranges of technical analytical skills to contribute to an increasingly data-heavy field. However, it has been argued that educational data scientists are a ‘scarce breed’ (Buckingham Shum et al., 2013) and that more resources are needed to support the next generation of early career researchers in the education field. At the same time, little is known about how early career education researchers feel towards learning analytics and whether it is important to their current and future research practices. Using a thematic analysis of a participatory learning analytics workshop discussions with 25 early career education researchers, we outline in this article their ambitions, challenges and anxieties towards learning analytics. In doing so, we have provided a roadmap for how the learning analytics field might evolve and practical implications for supporting early career researchers’ development
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Reflecting on incidents: Barriers and tactics
Learning from incidents (LFI) is key for energy companies to become safer. Researchers from the Open University discuss what comprises effective LFI, barriers that can prevent LFI, and tactics companies can use to overcome those barriers
Practice and Recommendations for Universal Design for Learning in Occupational Therapy Client Education
Background: Universal Design for Learning (UDL), an educational framework that describes flexible approaches to teaching and learning, can be used to address problems related to limitations in health literacy in health care settings.
Methods: This exploratory observational study, using a web-based online survey, was undertaken to discern how occupational therapists use the principles of UDL in educating their clients and to determine if differences exist between degree type or practice settings and UDL implementation.
Results: Of the 147 respondents only 30.6% indicated prior awareness of UDL principles. The most frequently cited means of client engagement were displaying enthusiasm and emphasizing importance of content; the most frequently cited means of representation was providing verbal instructions, and the most frequent means of action and expression was observing client performance or demonstration.
Conclusions: There is a clear need to increase both academic preparation and continuing education of occupational therapists to implement evidence-based principles of UDL to address diverse client health literacy and facilitate positive health outcomes. Opportunities for increased UDL implementation are discussed, building on the commitment of current therapists to meet the needs of their clients
Theory and evidence of global Rossby waves in upper main-sequence stars: r-mode oscillations in many Kepler stars
Asteroseismic inference from pressure modes (p modes) and buoyancy, or gravity, modes (g modes) is ubiquitous for stars across the Hertzsprung–Russell diagram. Until now, however, discussion of r modes (global Rossby waves) has been rare. Here we derive the expected frequency ranges of r modes in the observational frame by considering the visibility of these modes. We find that the frequencies of r modes of azimuthal order m appear as groups at slightly lower frequency
than m times the rotation frequency. Comparing the visibility curves for r modes with Fourier amplitude spectra of Kepler light curves of upper main-sequence B, A, and F stars, we find that r modes are present in many γ Dor stars (as first discovered by Van Reeth et al.), spotted stars, and so-called heartbeat stars, which are highly eccentric binary stars. We also find a signature of r modes in a frequently bursting Be star observed by Kepler. In the amplitude spectra of moderately
to rapidly rotating γ Dor stars, r-mode frequency groups appear at lower frequency than prograde g-mode frequency groups, while in the amplitude spectra of spotted early A to B stars, groups of symmetric (with respect to the equator) r-mode frequencies appear just below the frequency of a structured peak that we suggest represents an approximate stellar rotation rate. In many heartbeat stars, a group of frequencies can be fitted with symmetric m = 1 r modes, which can be used to
obtain rotation frequencies of these stars
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Planning virtual and hybrid events: steps to improve inclusion and accessibility
The past decade has seen a global transformation in how we communicate and connect with one another, making it easier to network and collaborate with colleagues worldwide. The COVID-19 pandemic led to a rapid and unplanned shift toward virtual platforms, resulting in several accessibility challenges that have excluded many people during virtual events. Virtual and hybrid conferences have the potential to present opportunities and collaborations to groups previously excluded from purely in-person conference formats. This can only be achieved through thoughtful and careful planning with inclusion and accessibility in mind, learning lessons from previous events' successes and failures. Without effective planning, virtual and hybrid events will replicate many biases and exclusions inherent to in-person events. This article provides guidance on best practices for making online/virtual and hybrid events more accessible based on the combined experiences of diverse groups and individuals who have planned and run such events. Our suggestions focus on the accessibility considerations of three event planning stages: (1) pre-event planning, (2) on the day/during the event, and (3) after the event. Ensuring accessibility and inclusivity in designing and running virtual events can help everyone engage more meaningfully, resulting in more impactful discussions that will more fully include contributions from the many groups with limited access to in-person events. However, while this article is intended to act as a starting place for inclusion and accessibility in online and hybrid event planning, it is not a fully comprehensive guide. As more events are run, it is expected that new insights and experiences will be gained, helping to continually update standards.</p
PL - 039 Heat Shock Proteins in human single skeletal muscle fibres resist age associated alterations and differentially respond to high-intensity exercise training
Objective Heat shock proteins (HSPs) are ubiquitously expressed proteins that help preserve cellular homeostasis. Within mammalian skeletal muscle three of the better characterised HSPs are HSP72, HSP27 and αB-crystallin. Among other roles, these three HSPs are involved in regulation of muscle mass and function and may be of importance in ageing. HSP’s are fibre-type dependent in rat skeletal muscle and thus examining these proteins in humans should be completed on the single fibre level, particularly in ageing where maladaptations primarily occur in Type II fibres. High-Intensity Training (HIT) is a commonly used method to improve muscle health and function in the elderly, but HSP adaptability to training has not yet been investigated.
Methods This study examined isolated single muscle fibre segments collected from freeze-dried vastus lateralis muscle samples from young (25 /- 3 year old) and older (70 /- 4 year old) healthy individuals. A further sample was collected from the older individuals following 12 weeks of HIT, where they performed 4 x 4 min @ ~90-95% of peak heart rate (HR), with 4 min active recovery at 50-60% peak HR
Results Basal expression of HSP’s in skeletal muscle: HSP70 tended to be higher in Type I fibres compared to Type II in young adults (p=0.08) and was higher in Type I compared to Type II fibres of older adults (p=0.03). HSP27 abundance was higher in Type I fibres compared to Type II in young adults (p=0.01) and tended to be higher in Type I compared to Type II fibres in older adults (p=0.07). The abundance of αβ-crystallin was more abundant in Type I fibres compared to Type II in both young and older adults (p<0.05). Preliminary data revealed that the abundance of pABCser59 and pHSP2782 displayed no fibre-type specific abundances in either young or older adults.
Age effects on HSP’s: There was no difference in the abundance of HSP70, HSP27, ABC or pHSP2782 between young and older adults in either Type I or Type II fibres. There was an increase in the abundance of pABCser59 in Type I fibres in older adults compared to Type I fibres of young adults (p=0.03), with no difference in Type II fibres.
Effects of HIT on HSP’s: HIT in the older individuals increased the abundance of HSP70 in Type I fibres (p<0.01) but not Type II. HIT tended to decrease the abundance of HSP27 in Type I fibres (0.92±0.66, p=0.06) and tended to increase the abundance of αβ-crystallin in Type I fibres (1.03±1.51 p=0.07).
Conclusions These results revealed that in healthy, older individuals, the basal levels of HSP27, ABC or pHSP2782 are not different to those in young adults in either Type I or Type II fibres. This could indicate that the muscle from the older individuals was not compromised. Interestingly, in response to HIT there were varying changes between these HSP’s, and of note these occurred only in Type I fibres. Given that during HIT Type II fibres would be activated to a greater extent, it appears that the recovery phases of the HIT were most responsive to HSPs
Exome Sequencing as a Diagnostic Tool for Pediatric-Onset Ataxia
Ataxia demonstrates substantial phenotypic and genetic heterogeneity. We set out to determine the diagnostic yield of exome sequencing in pediatric patients with ataxia without a molecular diagnosis after standard-of-care assessment in Canada. FORGE (Finding Of Rare disease GEnes) Canada is a nation-wide project focused on identifying novel disease genes for rare pediatric diseases using whole-exome sequencing. We retrospectively selected all FORGE Canada projects that included cerebellar ataxia as a feature. We identified 28 such families and a molecular diagnosis was made in 13; a success rate of 46%. In 11 families, we identified mutations in genes associated with known neurological syndromes and in two we identified novel disease genes. Exome analysis of sib pairs and/or patients born to consanguineous parents was more likely to be successful (9/13) than simplex cases (4/15). Our data suggest that exome sequencing is an effective first line test for pediatric patients with ataxia where a specific single gene is not immediately suspected to be causative. © 2013 The Authors. *Human Mutation published by Wiley Periodicals, Inc
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