Geranium's response to compost based substrates

8 páginas, 2 figuras, 3 tablas, 10 referencias.-- International Symposium on Composting and use of Composted Materials for Horticulture, celebrado del 5-11 de abril 1997, en Ayr, Scotland, United Kingdom.The effects of compost based substrates on growth and nutrition of geranium (Pelargonium zonale cv Lucky Break F2) were investigated. Substrates of manure compost, cotton gin trash compost, municipal solid waste compost and pine bark utilized as potting media for domestic use, produced an underdevelopment of geranium plants with respect to the control. This behaviour is related to the inferior physical properties of the compost-based potting media, nitro gen immobilization due to the high C/N ratio of pine bark, and probably lack of available phosphorus originated by high calcium and high pH of the compost-based media. Nitrogen fertilization and a longer period of cultivation diminished the differences between plants grown in the control and in compost-based media. Plants grown in compost mixtures which were rich in K showed K and Ca leaf contents closer to the optimum range than did control plants.This work was supported by the Agencia de Medio Ambiente of the Junta de Andalucía and by Fertilizantes Orgánicos Melguizo, S. L.Peer reviewe

Encuesta de evaluación de la "usabilidad" de la sede web de la Biblioteca Universitaria de Córdoba

Comunicación presentada a las XV Jornadas Bibliotecarias de Andalucía: Bibliotecas, rompiendo barreras, tejiendo redes. Córdoba, 15-17, Octubre, 2009La unión cada vez más estrecha entre la biblioteca universitaria y su sede web es incuestionable. Este trabajo es un estudio de usabilidad de la sede web de la Biblioteca Universitaria de Córdoba. El estudio se ha llevado a cabo realizando una encuesta de evaluación entre dos grupos de usuarios/alumnos, con dos ediciones sucesivas de la página, y un tercer grupo de usuarios/expertos, con la última edición. Los resultados obtenidos muestran considerables diferencias en la forma de interactuar con el sitio web entre los dos primeros grupos de usuarios con respecto al tercero. El estudio de usabilidad ha sido una herramienta muy útil que, además, nos permitirá desarrollar futuras mejoras del sitio web que cumplan con las necesidades y expectativas de los usuarios

Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation

Dual-specificity phosphatases (DUSPs) are important regulators of neuronal cell growth and differentiation by targeting proteins essential to neuronal survival in signaling pathways, among which the MAP kinases (MAPKs) stand out. DUSPs include the MAPK phosphatases (MKPs), a family of enzymes that directly dephosphorylate MAPKs, as well as the small-size atypical DUSPs, a group of low molecular-weight enzymes which display more heterogeneous substrate specificity. Neuroblastoma (NB) is a malignancy intimately associated with the course of neuronal and neuroendocrine cell differentiation, and constitutes the source of more common extracranial solid pediatric tumors. Here, we review the current knowledge on the involvement of MKPs and small-size atypical DUSPs in NB cell growth and differentiation, and discuss the potential of DUSPs as predictive biomarkers and therapeutic targets in human NB.This work was partially supported by the grants: BIO13/CI/001/BC from BIOEF (EITB maratoia), Basque Country, Spain; SAF2013-48812-R from the Ministerio de Educacion y Ciencia (to R.P.), and SAF2016-79847-R from the Ministerio de Economia y Competitividad (Spain and Fondo Europeo de Desarrollo Regional) (to R.P. and J.I.L.); and 239813 from the Research Council of Norway (to C.E.N-X.)

Desarrollo de modelos 3D de los edificios de contención de la Central Nuclear de Almaraz y de la Central Nuclear de Trillo con el código GOTHIC 8.0

El análisis de los accidentes tipo LOCA o MSLB en una contención PWR-W normalmente se simulan con la opción de volúmenes de control con parámetros agrupados en GOTHIC, ya que es lo que hasta ahora se ha considerado adecuado para el análisis de licencia. Sin embargo, para el estudio de detalle del comportamiento termo-hidráulico de cada recinto de la contención, podría ser más adecuado contar con un modelo tridimensional que representase más fielmente la geometría de la contención. El objetivo de la primera fase del proyecto de investigación de CNAT y la UPM es la construcción de varios modelos tridimensionales detallados con el código GOTHIC 8.0 de los edificios de contención de una planta tipo PWR-W y KWU, correspondientes a la Central Nuclear de Almaraz (CNA) y Trillo (CNT) respectivamente

Prevalence of salivary Epstein-Barr virus in potentially malignant oral disorders and oral squamous cell carcinoma

Background: To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders. Material and Methods: Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR. Results: The highest percentage of positive salivary EBV DNA corresponded to the OSCC group (58.3%), followed by the PMD group (41.7%) and the controls (40.4%). The differences between groups were not statistically significant, however (p>0.05). Conclusions: Salivary EBV DNA was more prevalent in OSCC than in PMD or the controls

Three-dimensional Containment Accident Analysis using different approaches in Almaraz NPP

Containment Design Basis Accident analysis are usually performed using lumped-parameters models as this kind of models do not require high computational resources. Moreover, they offer overall good results of average pressure and temperature evolution. However, in order to perform a detailed local analysis, a thermal-hydraulic behavior study of every containment room may be necessary. To achieve this goal, a more detailed containment 3D model is imperative for capturing the local phenomena which occurs during a mass and energy release accident. During the last years in the collaborative project between the UPM and CNAT, several Almaraz NPP containment 3D models have been developed. The most precise one, called Detailed Integral Model, is able to obtain results with a very high resolution. However, this approach requires also high computational resources. For this reason two new models, called Multi-Zone Models, were developed with a coarser nodalization and therefore a lower computational requirement is needed. In this paper, the new modeling approach is described. A LBLOCA has been simulated in the Multi-Zone Model and it has been compared with the results obtained from the Detailed Integral Model. After analyzing the results, it can be concluded that the thermal-hydraulic evolutions are similar although the local variables differ in some cases. Taking into account the differences between models, a criteria in the use of the different approaches described has been stated depending on the analysis objective

Double-Ended LBLOCA Containment Analysis in Trillo NPP with GOTHIC 8.1

The radioactive material confinement in a nuclear power plant (NPP), , is a fundamental safety function to be ensured during a design basis accident (DBA). For plant licensing analysis, the containment is usually modeled with a lumped parameter approach. The assumption that within each region the fluid is well mixed is inherent to this approach. However, the containment is a large building with a complex configuration. It is distributed in several compartments that avoid the well mixing of the fluid and that provoke three-dimensional effects that affect the thermal–hydraulic behavior. Reactors like Trillo NPP are highly compartmentalized in order to reduce the dose to the personnel, in contrast with PWR-W reactors that present a more diaphanous layout. Accordingly, this kind of reactors are more liable to have three dimensional effects and/or local differences than a PWR-W. The collaborative project between the UPM and CNAT has enabled the development of highly detailed three-dimensional models of the Trillo NPP containment building. The objective of this study is the detailed 3D thermal-hydraulic analysis during a mass and energy release where local effects can be observed. Most of DBA analysis are performed using lumped-parameters models which only allow to know the average containment state, and that has several assumptions related with 0D models. For this reason a generic double-ended LBLOCA is simulated in a GOTHIC 3D model in order to study the local phenomenology occurring during this kind of transient. Analyzing the results, an homogeneous pressurization over the whole containment can be observed, with the exception of the rooms near the break. This is predictable given that pressure is transmitted at the speed of sound. However, temperature evolution is different between compartments. Temperature behavior obeys to convective-diffusive processes, and it presents strong differences between compartments that cannot be seen with lumped parameters models. The steam residence time becomes one of the critical parameters in the containment thermal behavior, and this is strongly dependent on the building geometry

Benign tumors of the oral mucosa: A study of 300 patients

Objectives: To analyze the frequency and type of the most common benign tumors of the oral mucosa found at the Hospital Stomatology Service, and to study the clinical characteristics and possible etiological factors. Material and Methods: This is a retrospective study of 300 patients with histologically diagnosed benign tumors of the oral mucosa. Data was compiled for each case, documenting information relating to age, gender, medication, habits (smoking, oral hygiene), anamnesis (reason for consultation, symptomatology, evolution), and the characteristics of the lesion (site, color, size, surface, consistency, and base). Results: Of all the tumors studied, 53% were histologically diagnosed as fibroma. In the study of prevalence of benign tumors of the oral mucosa, no differences were found for age; however there were differences according to gender, finding a greater prevalence of fibromas, pyogenic granulomas, and giant cell granulomas in women, at a ratio of 2:1. The group of tumors studied showed a significantly asymptomatic behaviour, and self-limiting and slow growth. With respect to the possible etiologic agents, we found no statistically significant differences between them. Conclusions: Following the study of 300 patients histologically diagnosed with benign tumor of the oral mucosa, we can state that with regard to prevalence, we found significant differences with respect to gender, being more frequent in women. The fibroma is the most frequent benign tumor of the oral cavity

Osteonecrosis of the jaws by intravenous bisphosphonates and osteoradionecrosis : a comparative study

Aims: We analyze the possible clinical differences between bone jaw exposed areas in ONJ (osteonecrosis of the jaws) and ORN (osteoradionecrosis). Patients and method: Group 1 was composed with 53 ONJ cases and group 2 with 20 ORN cases. In both groups we analyzed, the major size of the exposed bone areas, the number of exposed areas, the location on the jaws and the presence of others associated and severe complications, such as skin fistulas and jaw fractures. We also investigated the possible local aetiology or trigger factor of the lesions. Results: The major size of the bone exposed areas was 2.29±2.02(mean ± std.dev) in group 1 and 2.7±2.9 (mean ± std.dev) in group 2 (p>0.05). The number of exposed areas was 1.8±1.34 (mean ± std.dev) in group 1 and 1.2±0.55 (mean ± std.dev) in group 2 (p>0.05). There were more fractures in the second group (20%) (p<0.05), and skin fistulas (35%) (p<0.05). We found more patients in group 1 in which the dental extraction was the local aetiology of the bone necrosis (35 cases, 66.03%), while in group 2 there were 8 (40%) (p<0.05). Conclusions: In our study with ONJ there were not differences in the major size of the bone exposed areas, but there were more lesions per patient than in group with ORN. The severity of the complications, such as jaw fractures and skin fistulas were higher in ORN, and in this group it was more frequent the spontaneous lesions than in the ONJ where it is more frequent following dental extractions

The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases

Clear cell renal cell carcinoma (CCRCC) is a heterogeneous and complex disease that frequently develops distant metastases. Fibroblast activation protein (FAP) is a serine peptidase the expression of which in cancer-associated fibroblasts has been associated with higher risk of metastases and poor survival. The objective of this study was to evaluate the role of FAP in metastatic CCRCC (mCCRCC). A series of 59 mCCRCC retrospectively collected was included in the study. Metastases developed either synchronous (n = 14) or metachronous to renal disease (n = 45). Tumor specimens were obtained from both primary lesion (n = 59) and metastases (n = 54) and FAP expression was immunohistochemically analyzed. FAP expression in fibroblasts from primary tumors correlated with FAP expression in the corresponding metastatic lesions. Also, primary and metastatic FAP expression was correlated with large tumor diameter (>7cm), high grade (G3/4), high stage (pT3/4), tumor necrosis and sarcomatoid transformation. The expression of FAP in primary tumors and in their metastases was associated both with synchronous metastases and also with metastases to the lymph nodes. FAP expression in the primary tumor was correlated with worse 10-year overall survival. Immunohistochemical detection of FAP in the stromal tumor fibroblasts could be a biomarker of early lymph node metastatic status and therefore could account for the poor prognosis of FAP positive CCRCC.This work was partially funded by Grant SAF2013-48812-R from Ministerio de Economia y Competitividad (Spain), IT 8-11/13 from de Basque Government and EHUA14/25 from de University of the Basque Country (UPV/EHU). The current work has been developed as PhD project of PE and MB, who are recipients of a Predoctoral Fellowship from the Basque Government (Exp no PRE_2013_1_762 and PRE_2015_2_0148). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript