Farming in the European Union: from organic to sustainable. An assessment of a legal transition based on land stewardship and participatory guarantee systems

The conventional agricultural production system is not sustainable. Organic agriculture is assumed to be sustainable from the environmental perspective, and its production and labelling has been regulated in the European Union (EU). The EU organic regime has been challenged by proponents of agroecology, a philosophy that merges agriculture and ecology and considers environmental and social aspects. Some other initiatives at the local and regional level propose different ways of producing food sustainably. In 2015, a Spanish environmental NGO called RCTCMM launched a market of products coming from land stewardship (LS) agreements certified with participatory guarantee systems (PGSs), claiming it to be a sustainable alternative to the products certified as EU organic. Using strong/weak and soft-path/hard-path sustainability frameworks I analyse the sustainability features of the EU organic regime, agroecology, LS, and PGSs from the environmental and social points of view. I also do a SWOT analysis on the implementation of RCTCMM’s project. My analysis finds: 1) the EU organic regime is not sustainable because it does not take into account important local and global environmental impacts, and leaves out of the market responsible farmers who cannot compete in the global markets, afford the cost of certification, or participate in the selection of the certification criteria; 2) agroecology is a strong sustainability, soft-path solution from both social and environmental dimensions; 3) LS and PGSs can solve some of the current EU organic regime’s sustainability issues, with multifunctional agriculture, short commercial channels, and inclusiveness and participation of farmers in the certification process; and 4) RCTCMM’s project needs to improve some organisational aspects for the successful implementation of their initiative in Spain, although there are other external risks that require changes at the EU-level to dissipate. Using transition theory, I offer three legal transitions towards a less unsustainable EU regime: A) a ‘patch’ to the current EU organic regime with an update of the current criteria and the allowance of group certification; B) a parallel alternative system of incentives for initiatives like PGSs and LS; and C) a reform of the whole EU agricultural regime conforming to agroecological principles. I suggest Option B because it is a strong sustainability alternative and it is the easiest to implement considering the transaction costs involved in the other two

Multi-objective optimization of the geometry of a double wishbone suspension system

The vehicle suspension system optimal design problem is multi-objective, has a hierarchical multi-level structure and presents couplings with the rest of the vehicle design. Moreover, many of the vehicle performances are dependent of the suspension system, specifically on its geometry. For this reason, it is desirable to develop a strategy in which the geometry of the suspension system is automatically generated with optimal characteristics. For this type of problems, the Analytical Target Cascading (ATC) brings a powerful optimization strategy that permits the management of a complex optimal design problem in a partitioned manner. This work proposes a new approach for the automatic optimal geometry generation of the suspension system of the vehicle, the development of the optimization problem in order to use the ATC optimization strategy and a case study in which a full-scale functional prototype is designed with the use of the developed tools

Proteccion a la Salud en Chile, derecho real o aparente?

72 p.La salud es un tema de interés general presente en cada etapa de la vida de las personas, por esto, no solo la medicina se ha ocupado de ella, sino también el derecho, por medio de la creación de distintas Leyes tanto a nivel nacional como internacional, que permitan su protección. La salud es un derecho que requiere para subsistir, un sistema sanitario que garantice a todos por igual un oportuno y completo acceso a la salud. El Estado es el responsable de garantizar este derecho evitando su vulneración, estableciendo mecanismos de acción, en caso de existir una violación a este derecho fundamental. Nuestra Constitución, considera el Derecho a la Salud como un derecho fundamental, estableciéndolo así en el artículo 19 Nº 9. Se intentará definir la realidad de la salud en nuestro país y a nivel internacional, intentando plasmar las dificultades que presenta el Recurso de Protección en salud

Pautas para la organizacion y composicion de Escritos Cientificos

La conferencia tuvo como finalidad proporcionar al docente universitario de Santo Domingo de Guzmán las pautas fundamentales de organización y composición de escritos científicos. Nuestro propósito fue comprometer al docente para que dichas pautas se constituyan en herramientas permanentes del ejercicio didáctico. De modo que el estudiante se familiarice y haga suyo estos lineamientos, como parte de su actuar en el cumplimiento eficiente de sus tareas académicas e investigativas. Los estudiantes universitarios requieren de un asesoramiento planificado para el éxito de sus aprendizajes y afinamiento de sus destrezas, en el uso y aplicación correcta, en la organización y composición de sus trabajos. Palabras Clave: Escritos científicos, organización, composición, cuadros, tablas, figuras, citas, abreviaturas latinas

Estimation of the lot fraction defective in a finite lot of products with auxiliary quality characteristics

Many companies use sampling plans for the acceptance or rejection of lots of prod-ucts. The final o utcome o f t his d ecision-making p rocess i s b ased o n t he i nspection of a sample of products selected from a lot under inspection, where a quality character-istic is observed. An important parameter of interest related to acceptance sampling for attributes is the proportion of defective items. This parameter is unknown for a given lot of products, but it can be estimated from the aforementioned sample infor-mation. Additional quality characteristics can be observed at the inspection stage. We propose to use this auxiliary information to obtain more accurate estimators of the lot fraction defective at the estimation stage. Various relevant applications of this process are described. For possible scenarios that may arise in practice, the empirical properties of the suggested estimation methods are investigated using Monte Carlo simulations, and desirable results are obtained when there is a strong relationship between the quality characteristic of interest and the auxiliary quality characteristic

Phenotipic integration does not constrain phenotypic plasticity: differential plasticity of traits is associated to their integration across environments

ResearchUnderstanding constraints to phenotypic plasticity is key given its role on the response of organisms to environmental change. It has been suggested that phenotypic integration, the structure of trait covariation, could limit trait plasticity. However, the relationship between plasticity and integration is far from resolved. Using a database of functional plasticity to drought of a Mediterranean shrub that included 20 ecophysiological traits, we assessed environmentally-induced changes in phenotypic integration and whether integration constrained the expression of plasticity, accounting for the within-environment phenotypic variation of traits. Furthermore, we provide the first test of the association between differential trait plasticity and trait integration across an optimum and a stressful environment. Phenotypic plasticity was positively associated with phenotypic integration in both environments, but this relationship was lost when phenotypic variation was considered. The similarity in the plastic response of two traits predicted their integration across environments, with integrated traits having more similar plasticity. Such variation in the plasticity of traits partly explained the lower phenotypic integration found in the stressful environment. We found no evidence that integration may constitute an internal constraint to plasticity. Rather, we present the first empirical demonstration that differences in plastic responses may involve a major reorganization of the relationships among traits, and challenge the notion that stress generally induces a tighter phenotypeinfo:eu-repo/semantics/publishedVersio

Partial Activation of SA- and JA-Defensive Pathways in Strawberry upon Colletotrichum acutatum Interaction

[EN] Understanding the nature of pathogen host interaction may help improve strawberry (Fragaria x anahassa) cultivars. Plant resistance to pathogenic agents usually operates through a complex network of defense mechanisms mediated by a diverse array of signaling molecules. In strawberry, resistance to a variety of pathogens has been reported to be mostly polygenic and quantitatively inherited, making it difficult to associate molecular markers with disease resistance genes. Colletotrichum acutaturn spp. is a major strawberry pathogen, and completely resistant cultivars have not been reported. Moreover, strawberry defense network components and mechanisms remain largely unknown and poorly understood. Assessment of the strawberry response to C. acutatum included a global transcript analysis, and acidic hormones SA and JA measurements were analyzed after challenge with the pathogen. Induction of transcripts corresponding to the SA and JA signaling pathways and key genes controlling major steps within these defense pathways was detected. Accordingly, SA and JA accumulated in strawberry after infection. Contrastingly, induction of several important SA, JA, and oxidative stress-responsive defense genes, including FaPR1-1, FaLOX2, FaJAR1, FaPDF1, and FaGST1, was not detected, which suggests that specific branches in these defense pathways (those leading to FaPR1-2, FaPR2-1, FaPR2-2, FaAOS, FaPR5, and FaPR10) were activated. Our results reveal that specific aspects in SA and JA dependent signaling pathways are activated in strawberry upon interaction with C. acutatum. Certain described defense-associated transcripts related to these two known signaling pathways do not increase in abundance following infection. This finding suggests new insight into a specific putative molecular strategy for defense against this pathogen.Authors are grateful to Dr. JM Lopez-Aranda (IFAPA-Centro de Churriana) for providing micropropagated strawberry plants and to Nicolas Garcia-Caparros for technical assistance. Authors also want to thank Kevin M. Folta for his insightful comments on the paper. This work was supported by Junta de Andalucia, Spain [Proyectos de Excelencia P07-AGR-02482/P12-AGR-2174, and grants to Grupo-BIO278].Amil-Ruiz, F.; Garrido-Gala, J.; Gadea Vacas, J.; Blanco-Portales, R.; Munoz-Merida, A.; Trelles, O.; De Los Santos, B.... (2016). Partial Activation of SA- and JA-Defensive Pathways in Strawberry upon Colletotrichum acutatum Interaction. Frontiers in Plant Science. 7(1036). https://doi.org/10.3389/fpls.2016.01036S71036Acosta, I. F., & Farmer, E. E. (2010). Jasmonates. The Arabidopsis Book, 8, e0129. doi:10.1199/tab.0129Al-Shahrour, F., Diaz-Uriarte, R., & Dopazo, J. (2004). FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes. Bioinformatics, 20(4), 578-580. doi:10.1093/bioinformatics/btg455Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990). Basic local alignment search tool. Journal of Molecular Biology, 215(3), 403-410. doi:10.1016/s0022-2836(05)80360-2Amil-Ruiz, F., Blanco-Portales, R., Muñoz-Blanco, J., & Caballero, J. L. (2011). The Strawberry Plant Defense Mechanism: A Molecular Review. Plant and Cell Physiology, 52(11), 1873-1903. doi:10.1093/pcp/pcr136Amil-Ruiz, F., Garrido-Gala, J., Blanco-Portales, R., Folta, K. M., Muñoz-Blanco, J., & Caballero, J. L. (2013). Identification and Validation of Reference Genes for Transcript Normalization in Strawberry (Fragaria × ananassa) Defense Responses. PLoS ONE, 8(8), e70603. doi:10.1371/journal.pone.0070603Arroyo, F. T., Moreno, J., García-Herdugo, G., Santos, B. D. los, Barrau, C., Porras, M., … Romero, F. (2005). Ultrastructure of the early stages of Colletotrichum acutatum infection of strawberry tissues. Canadian Journal of Botany, 83(5), 491-500. doi:10.1139/b05-022Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., … Sherlock, G. (2000). Gene Ontology: tool for the unification of biology. Nature Genetics, 25(1), 25-29. doi:10.1038/75556Aviv, D. H., Rustérucci, C., Iii, B. F. H., Dietrich, R. A., Parker, J. E., & Dangl, J. L. (2002). Runaway cell death, but not basal disease resistance, inlsd1is SA- andNIM1/NPR1-dependent. The Plant Journal, 29(3), 381-391. doi:10.1046/j.0960-7412.2001.01225.xBak, S., Beisson, F., Bishop, G., Hamberger, B., Höfer, R., Paquette, S., & Werck-Reichhart, D. (2011). Cytochromes P450. The Arabidopsis Book, 9, e0144. doi:10.1199/tab.0144Baniwal, S. K., Bharti, K., Chan, K. Y., Fauth, M., Ganguli, A., Kotak, S., … von Koskull-DÖring, P. (2004). Heat stress response in plants: a complex game with chaperones and more than twenty heat stress transcription factors. Journal of Biosciences, 29(4), 471-487. doi:10.1007/bf02712120Bhattacharjee, S. (2012). The Language of Reactive Oxygen Species Signaling in Plants. Journal of Botany, 2012, 1-22. doi:10.1155/2012/985298Birkenbihl, R. P., Diezel, C., & Somssich, I. E. (2012). Arabidopsis WRKY33 Is a Key Transcriptional Regulator of Hormonal and Metabolic Responses toward Botrytis cinerea Infection. Plant Physiology, 159(1), 266-285. doi:10.1104/pp.111.192641Caarls, L., Pieterse, C. M. J., & Van Wees, S. C. M. (2015). How salicylic acid takes transcriptional control over jasmonic acid signaling. Frontiers in Plant Science, 6. doi:10.3389/fpls.2015.00170Casado-Díaz, A., Encinas-Villarejo, S., Santos, B. de los, Schilirò, E., Yubero-Serrano, E.-M., Amil-Ruíz, F., … Caballero, J.-L. (2006). Analysis of strawberry genes differentially expressed in response to Colletotrichum infection. Physiologia Plantarum, 128(4), 633-650. doi:10.1111/j.1399-3054.2006.00798.xCharng, Y., Liu, H., Liu, N., Chi, W., Wang, C., Chang, S., & Wang, T. (2006). A Heat-Inducible Transcription Factor, HsfA2, Is Required for Extension of Acquired Thermotolerance in Arabidopsis. Plant Physiology, 143(1), 251-262. doi:10.1104/pp.106.091322Chung, S. H., Rosa, C., Scully, E. D., Peiffer, M., Tooker, J. F., Hoover, K., … Felton, G. W. (2013). Herbivore exploits orally secreted bacteria to suppress plant defenses. Proceedings of the National Academy of Sciences, 110(39), 15728-15733. doi:10.1073/pnas.1308867110Curry, K. J., Abril, M., Avant, J. B., & Smith, B. J. (2002). Strawberry Anthracnose: Histopathology of Colletotrichum acutatum and C. fragariae. Phytopathology®, 92(10), 1055-1063. doi:10.1094/phyto.2002.92.10.1055Debode, J., Van Hemelrijck, W., Baeyen, S., Creemers, P., Heungens, K., & Maes, M. (2009). Quantitative detection and monitoring ofColletotrichum acutatumin strawberry leaves using real-time PCR. Plant Pathology, 58(3), 504-514. doi:10.1111/j.1365-3059.2008.01987.xDempsey, D. A., & Klessig, D. F. (2012). SOS – too many signals for systemic acquired resistance? Trends in Plant Science, 17(9), 538-545. doi:10.1016/j.tplants.2012.05.011Dodds, P. N., & Rathjen, J. P. (2010). Plant immunity: towards an integrated view of plant–pathogen interactions. Nature Reviews Genetics, 11(8), 539-548. doi:10.1038/nrg2812Doehlemann, G., Wahl, R., Horst, R. J., Voll, L. M., Usadel, B., Poree, F., … Kämper, J. (2008). Reprogramming a maize plant: transcriptional and metabolic changes induced by the fungal biotroph Ustilago maydis. The Plant Journal, 56(2), 181-195. doi:10.1111/j.1365-313x.2008.03590.xDong, X. (2004). NPR1, all things considered. Current Opinion in Plant Biology, 7(5), 547-552. doi:10.1016/j.pbi.2004.07.005Durgbanshi, A., Arbona, V., Pozo, O., Miersch, O., Sancho, J. V., & Gómez-Cadenas, A. (2005). Simultaneous Determination of Multiple Phytohormones in Plant Extracts by Liquid Chromatography−Electrospray Tandem Mass Spectrometry. Journal of Agricultural and Food Chemistry, 53(22), 8437-8442. doi:10.1021/jf050884bEl Oirdi, M., El Rahman, T. A., Rigano, L., El Hadrami, A., Rodriguez, M. C., Daayf, F., … Bouarab, K. (2011). Botrytis cinerea Manipulates the Antagonistic Effects between Immune Pathways to Promote Disease Development in Tomato. The Plant Cell, 23(6), 2405-2421. doi:10.1105/tpc.111.083394Encinas-Villarejo, S., Maldonado, A. M., Amil-Ruiz, F., de los Santos, B., Romero, F., Pliego-Alfaro, F., … Caballero, J. L. (2009). Evidence for a positive regulatory role of strawberry (Fragaria×ananassa) Fa WRKY1 and Arabidopsis At WRKY75 proteins in resistance. Journal of Experimental Botany, 60(11), 3043-3065. doi:10.1093/jxb/erp152Freeman, S., Horowitz, S., & Sharon, A. (2001). Pathogenic and Nonpathogenic Lifestyles in Colletotrichum acutatum from Strawberry and Other Plants. Phytopathology®, 91(10), 986-992. doi:10.1094/phyto.2001.91.10.986Freeman, S., Katan, T., & Shabi, E. (1998). Characterization of Colletotrichum Species Responsible for Anthracnose Diseases of Various Fruits. Plant Disease, 82(6), 596-605. doi:10.1094/pdis.1998.82.6.596Gfeller, A., Dubugnon, L., Liechti, R., & Farmer, E. E. (2010). Jasmonate Biochemical Pathway. Science Signaling, 3(109), cm3-cm3. doi:10.1126/scisignal.3109cm3Grellet-Bournonville, C. F., Martinez-Zamora, M. G., Castagnaro, A. P., & Díaz-Ricci, J. C. (2012). Temporal accumulation of salicylic acid activates the defense response against Colletotrichum in strawberry. Plant Physiology and Biochemistry, 54, 10-16. doi:10.1016/j.plaphy.2012.01.019Guidarelli, M., Carbone, F., Mourgues, F., Perrotta, G., Rosati, C., Bertolini, P., & Baraldi, E. (2011). Colletotrichum acutatum interactions with unripe and ripe strawberry fruits and differential responses at histological and transcriptional levels. Plant Pathology, 60(4), 685-697. doi:10.1111/j.1365-3059.2010.02423.xHeidrich, K., Wirthmueller, L., Tasset, C., Pouzet, C., Deslandes, L., & Parker, J. E. (2011). Arabidopsis EDS1 Connects Pathogen Effector Recognition to Cell Compartment-Specific Immune Responses. Science, 334(6061), 1401-1404. doi:10.1126/science.1211641Horowitz, S., Freeman, S., & Sharon, A. (2002). Use of Green Fluorescent Protein-Transgenic Strains to Study Pathogenic and Nonpathogenic Lifestyles in Colletotrichum acutatum. Phytopathology®, 92(7), 743-749. doi:10.1094/phyto.2002.92.7.743Ikeda, M., Mitsuda, N., & Ohme-Takagi, M. (2011). Arabidopsis HsfB1 and HsfB2b Act as Repressors of the Expression of Heat-Inducible Hsfs But Positively Regulate the Acquired Thermotolerance. Plant Physiology, 157(3), 1243-1254. doi:10.1104/pp.111.179036Ikeda, M., & Ohme-Takagi, M. (2009). A Novel Group of Transcriptional Repressors in Arabidopsis. Plant and Cell Physiology, 50(5), 970-975. doi:10.1093/pcp/pcp048Khan, A. A., & Shih, D. S. (2004). Molecular cloning, characterization, and expression analysis of two class II chitinase genes from the strawberry plant. Plant Science, 166(3), 753-762. doi:10.1016/j.plantsci.2003.11.015Krinke, O., Ruelland, E., Valentová, O., Vergnolle, C., Renou, J.-P., Taconnat, L., … Zachowski, A. (2007). Phosphatidylinositol 4-Kinase Activation Is an Early Response to Salicylic Acid in Arabidopsis Suspension Cells. Plant Physiology, 144(3), 1347-1359. doi:10.1104/pp.107.100842Kubigsteltig, I., Laudert, D., & Weiler, E. W. (1999). Structure and regulation of the Arabidopsis thaliana allene oxide synthase gene. Planta, 208(4), 463-471. doi:10.1007/s004250050583Leandro, L. F. S., Gleason, M. L., Nutter, F. W., Wegulo, S. N., & Dixon, P. M. (2001). Germination and Sporulation of Colletotrichum acutatum on Symptomless Strawberry Leaves. Phytopathology®, 91(7), 659-664. doi:10.1094/phyto.2001.91.7.659Leon-Reyes, A., Van der Does, D., De Lange, E. S., Delker, C., Wasternack, C., Van Wees, S. C. M., … Pieterse, C. M. J. (2010). Salicylate-mediated suppression of jasmonate-responsive gene expression in Arabidopsis is targeted downstream of the jasmonate biosynthesis pathway. Planta, 232(6), 1423-1432. doi:10.1007/s00425-010-1265-zLi, J., Brader, G., Kariola, T., & Tapio Palva, E. (2006). WRKY70 modulates the selection of signaling pathways in plant defense. The Plant Journal, 46(3), 477-491. doi:10.1111/j.1365-313x.2006.02712.xLi, J., Brader, G., & Palva, E. T. (2004). The WRKY70 Transcription Factor: A Node of Convergence for Jasmonate-Mediated and Salicylate-Mediated Signals in Plant Defense. The Plant Cell, 16(2), 319-331. doi:10.1105/tpc.016980Liu, P.-P., von Dahl, C. C., Park, S.-W., & Klessig, D. F. (2011). Interconnection between Methyl Salicylate and Lipid-Based Long-Distance Signaling during the Development of Systemic Acquired Resistance in Arabidopsis and Tobacco. Plant Physiology, 155(4), 1762-1768. doi:10.1104/pp.110.171694Lodha, T. D., & Basak, J. (2011). Plant–Pathogen Interactions: What Microarray Tells About It? Molecular Biotechnology, 50(1), 87-97. doi:10.1007/s12033-011-9418-2López-Ráez, J. A., Verhage, A., Fernández, I., García, J. M., Azcón-Aguilar, C., Flors, V., & Pozo, M. J. (2010). Hormonal and transcriptional profiles highlight common and differential host responses to arbuscular mycorrhizal fungi and the regulation of the oxylipin pathway. Journal of Experimental Botany, 61(10), 2589-2601. doi:10.1093/jxb/erq089Maas, J. L. (Ed.). (1998). Compendium of Strawberry Diseases, Second Edition. doi:10.1094/9780890546178Makowski, R. M. D., & Mortensen, K. (1998). Latent infections and penetration of the bioherbicide agent Colletotrichum gloeosporioides f. sp. malvae in non-target field crops under controlled environmental conditions. Mycological Research, 102(12), 1545-1552. doi:10.1017/s0953756298006960Maleck, K., Levine, A., Eulgem, T., Morgan, A., Schmid, J., Lawton, K. A., … Dietrich, R. A. (2000). The transcriptome of Arabidopsis thaliana during systemic acquired resistance. Nature Genetics, 26(4), 403-410. doi:10.1038/82521Marcel, S., Sawers, R., Oakeley, E., Angliker, H., & Paszkowski, U. (2010). Tissue-Adapted Invasion Strategies of the Rice Blast Fungus Magnaporthe oryzae. The Plant Cell, 22(9), 3177-3187. doi:10.1105/tpc.110.078048Ndamukong, I., Abdallat, A. A., Thurow, C., Fode, B., Zander, M., Weigel, R., & Gatz, C. (2007). SA-inducible Arabidopsis glutaredoxin interacts with TGA factors and suppresses JA-responsive PDF1.2 transcription. The Plant Journal, 50(1), 128-139. doi:10.1111/j.1365-313x.2007.03039.xPajerowska-Mukhtar, K. M., Wang, W., Tada, Y., Oka, N., Tucker, C. L., Fonseca, J. P., & Dong, X. (2012). The HSF-like Transcription Factor TBF1 Is a Major Molecular Switch for Plant Growth-to-Defense Transition. Current Biology, 22(2), 103-112. doi:10.1016/j.cub.2011.12.015Pe�a-Cort�s, H., Barrios, P., Dorta, F., Polanco, V., S�nchez, C., S�nchez, E., & Ram�rez, I. (2004). Involvement of Jasmonic Acid and Derivatives in Plant Response to Pathogen and Insects and in Fruit Ripening. Journal of Plant Growth Regulation, 23(3), 246-260. doi:10.1007/s00344-004-0035-1Pernas, M., Ryan, E., & Dolan, L. (2010). SCHIZORIZA Controls Tissue System Complexity in Plants. Current Biology, 20(9), 818-823. doi:10.1016/j.cub.2010.02.062Pieterse, C. M. J., Leon-Reyes, A., Van der Ent, S., & Van Wees, S. C. M. (2009). Networking by small-molecule hormones in plant immunity. Nature Chemical Biology, 5(5), 308-316. doi:10.1038/nchembio.164Rahman, T. A. E., Oirdi, M. E., Gonzalez-Lamothe, R., & Bouarab, K. (2012). Necrotrophic Pathogens Use the Salicylic Acid Signaling Pathway to Promote Disease Development in Tomato. Molecular Plant-Microbe Interactions®, 25(12), 1584-1593. doi:10.1094/mpmi-07-12-0187-rRen, C.-M., Zhu, Q., Gao, B.-D., Ke, S.-Y., Yu, W.-C., Xie, D.-X., & Peng, W. (2008). Transcription Factor WRKY70 Displays Important but No Indispensable Roles in Jasmonate and Salicylic Acid Signaling. Journal of Integrative Plant Biology, 50(5), 630-637. doi:10.1111/j.1744-7909.2008.00653.xRietz, S., Stamm, A., Malonek, S., Wagner, S., Becker, D., Medina-Escobar, N., … Parker, J. E. (2011). Different roles of Enhanced Disease Susceptibility1 (EDS1) bound to and dissociated from Phytoalexin Deficient4 (PAD4) in Arabidopsis immunity. New Phytologist, 191(1), 107-119. doi:10.1111/j.1469-8137.2011.03675.xRobert-Seilaniantz, A., Grant, M., & Jones, J. D. G. (2011). Hormone Crosstalk in Plant Disease and Defense: More Than Just JASMONATE-SALICYLATE Antagonism. Annual Review of Phytopathology, 49(1), 317-343. doi:10.1146/annurev-phyto-073009-114447Cristina, M., Petersen, M., & Mundy, J. (2010). Mitogen-Activated Protein Kinase Signaling in Plants. Annual Review of Plant Biology, 61(1), 621-649. doi:10.1146/annurev-arplant-042809-112252Rouhier, N. (2006). Genome-wide analysis of plant glutaredoxin systems. Journal of Experimental Botany, 57(8), 1685-1696. doi:10.1093/jxb/erl001Ruepp, A. (2004). The FunCat, a functional annotation scheme for systematic classification of proteins from whole genomes. Nucleic Acids Research, 32(18), 5539-5545. doi:10.1093/nar/gkh894Rusterucci, C. (2001). The Disease Resistance Signaling Components EDS1 and PAD4 Are Essential Regulators of the Cell Death Pathway Controlled by LSD1 in Arabidopsis. THE PLANT CELL ONLINE, 13(10), 2211-2224. doi:10.1105/tpc.13.10.2211Sarowar, S., Zhao, Y., Soria-Guerra, R. E., Ali, S., Zheng, D., Wang, D., & Korban, S. S. (2011). Expression profiles of differentially regulated genes during the early stages of apple flower infection with Erwinia amylovora. Journal of Experimental Botany, 62(14), 4851-4861. doi:10.1093/jxb/err147Sasaki, Y. (2001). Monitoring of Methyl Jasmonate-responsive Genes in Arabidopsis by cDNA Macroarray: Self-activation of Jasmonic Acid Biosynthesis and Crosstalk with Other Phytohormone Signaling Pathways. DNA Research, 8(4), 153-161. doi:10.1093/dnares/8.4.153Schenk, P. M., Kazan, K., Manners, J. M., Anderson, J. P., Simpson, R. S., Wilson, I. W., … Maclean, D. J. (2003). Systemic Gene Expression in Arabidopsis during an Incompatible Interaction with Alternaria brassicicola. Plant Physiology, 132(2), 999-1010. doi:10.1104/pp.103.021683Simpson, D. W. (1991). Resistance toBotrytis cinereain pistillate genotypes of the cultivated strawberryFragaria ananassa. Journal of Horticultural Science, 66(6), 719-723. doi:10.1080/00221589.1991.11516203Shulaev, V., Sargent, D. J., Crowhurst, R. N., Mockler, T. C., Folkerts, O., Delcher, A. L., … Mane, S. P. (2010). The genome of woodland strawberry (Fragaria vesca). Nature Genetics, 43(2), 109-116. doi:10.1038/ng.740Song, W. C., Funk, C. D., & Brash, A. R. (1993). Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides. Proceedings of the National Academy of Sciences, 90(18), 8519-8523. doi:10.1073/pnas.90.18.8519Spoel, S. H., & Dong, X. (2012). How do plants achieve immunity? Defence without specialized immune cells. Nature Reviews Immunology, 12(2), 89-100. doi:10.1038/nri3141Spoel, S. H., Johnson, J. S., & Dong, X. (2007). Regulation of tradeoffs between plant defenses against pathogens with different lifestyles. Proceedings of the National Academy of Sciences, 104(47), 18842-18847. doi:10.1073/pnas.0708139104Staswick, P. E., & Tiryaki, I. (2004). The Oxylipin Signal Jasmonic Acid Is Activated by an Enzyme That Conjugates It to Isoleucine in Arabidopsis. The Plant Cell, 16(8), 2117-2127. doi:10.1105/tpc.104.023549Ten Hove, C. A., Willemsen, V., de Vries, W. J., van Dijken, A., Scheres, B., & Heidstra, R. (2010). SCHIZORIZA Encodes a Nuclear Factor Regulating Asymmetry of Stem Cell Divisions in the Arabidopsis Root. Current Biology, 20(5), 452-457. doi:10.1016/j.cub.2010.01.018Turner, J. G., Ellis, C., & Devoto, A. (2002). The Jasmonate Signal Pathway. The Plant Cell, 14(suppl 1), S153-S164. doi:10.1105/tpc.000679Tusher, V. G., Tibshirani, R., & Chu, G. (2001). Significance analysis of microarrays applied to the ionizing radiation response. Proceedings of the National Academy of Sciences, 98(9), 5116-5121. doi:10.1073/pnas.091062498Uknes, S., Mauch-Mani, B., Moyer, M., Potter, S., Williams, S., Dincher, S., … Ryals, J. (1992). Acquired resistance in Arabidopsis. The Plant Cell, 4(6), 645-656. doi:10.1105/tpc.4.6.645Vargas, W. A., Martín, J. M. S., Rech, G. E., Rivera, L. P., Benito, E. P., Díaz-Mínguez, J. M., … Sukno, S. A. (2012). Plant Defense Mechanisms Are Activated during Biotrophic and Necrotrophic Development of Colletotricum graminicola in Maize. Plant Physiology, 158(3), 1342-1358. doi:10.1104/pp.111.190397Venugopal, S. C., Jeong, R.-D., Mandal, M. K., Zhu, S., Chandra-Shekara, A. C., Xia, Y., … Kachroo, P. (2009). Enhanced Disease Susceptibility 1 and Salicylic Acid Act Redundantly to Regulate Resistance Gene-Mediated Signaling. PLoS Genetics, 5(7), e1000545. doi:10.1371/journal.pgen.1000545Vlot, A. C., Liu, P.-P., Cameron, R. K., Park, S.-W., Yang, Y., Kumar, D., … Klessig, D. F. (2008). Identification of likely orthologs of tobacco salicylic acid-binding protein 2 and their role in systemic acquired resistance inArabidopsis thaliana. The Plant Journal, 56(3), 445-456. doi:10.1111/j.1365-313x.2008.03618.xWang, D., Amornsiripanitch, N., & Dong, X. (2006). A Genomic Approach to Identify Regulatory Nodes in the Transcriptional Network of Systemic Acquired Resistance in Plants. PLoS Pathogens, 2(11), e123. doi:10.1371/journal.ppat.0020123Wang, D. (2005). Induction of Protein Secretory Pathway Is Required for Systemic Acquired Resistance. Science, 308(5724), 1036-1040. doi:10.1126/science.1108791Wang, G.-F., Seabolt, S., Hamdoun, S., Ng, G., Park, J., & Lu, H. (2011). Multiple Roles of WIN3 in Regulating Disease Resistance, Cell Death, and Flowering Time in Arabidopsis. Plant Physiology, 156(3), 1508-1519. doi:10.1104/pp.111.176776Wiermer, M., Feys, B. J., & Parker, J. E. (2005). Plant immunity: the EDS1 regulatory node. Current Opinion in Plant Biology, 8(4), 383-389. doi:10.1016/j.pbi.2005.05.010Windram, O., Madhou, P., McHattie, S., Hill, C., Hickman, R., Cooke, E., … Denby, K. J. (2012). Arabidopsis Defense against Botrytis cinerea: Chronology and Regulation Deciphered by High-Resolution Temporal Transcriptomic Analysis. Th