Numerical resolution of a reinforced random walk model arising in haptotaxis

In this paper we study the numerical resolution of a reinforced random walk model arising in haptotaxis and the stabilization of solutions. The model consists of a system of two differential equations, one parabolic equation with a second order non-linear term (haptotaxis term) coupled to an ODE in a bounded two dimensional domain. We assume radial symmetry of the solutions. The scheme of resolution is based on the application of the characteristics method together with a finite element one. We present some numerical simulations which illustrate some features of the numerical stabilization of solutions

Biodisponibilidad y bioaccesibilidad de polifenoles y flavonoides

87 p.Los polifenoles son compuestos orgánicos presentes en gran cantidad de alimentos vegetales, frutas, hierbas, algunas especias, entre otros. Los cuales corresponden a los antioxidantes más abundantes en nuestra dieta y cuya estructura química está compuesta por un anillo aromático unido a uno o más grupos hidroxilo, siendo estas estructuras simples y complejas. Presentan propiedades antioxidantes, cuyos efectos beneficiosos han tomado relevancia en los últimos años, como la protección contra efectos del estrés oxidativo en enfermedades cardiovasculares, neurodegenerativas, metabólicas, cáncer, entre otras. Gran parte de las investigaciones demostrativas de los efectos protectores de estos compuestos se llevan a cabo usando concentraciones mucho más altas de las consumidas en la dieta. Por este motivo es crucial comprender los factores involucrados en la digestión de los polifenoles junto con los conceptos de bioaccesibilidad y biodisponibilidad. El primer término se describe como la fracción de un compuesto que se libera de su matriz alimentaria dentro del tracto gastrointestinal, por lo tanto, se vuelve disponible para la absorción intestinal; el segundo estrechamente relacionado, corresponde a la fracción del componente ingerido disponible en el sitio de acción para su utilización en funciones fisiológicas, en este caso, los efectos antioxidantes. La bioaccesibilidad es establecida a partir de procedimientos in vitro, donde se pueden utilizar modelos estáticos como la Solubilidad y Dializabililidad o en modelos dinámicos, mayormente empleados, tales como el modelo gastrointestinal completo SHIME y el modelo gastrointestinal TIM. Respecto a la biodisponibilidad, esta es determinada mediante ensayos in vivo utilizando modelos celulares, donde se destaca el uso de la línea celular CACO-2 derivada de carcinoma de colon y otras líneas como HT29 (adenocarcinoma de colon)

The begomovirus Tomato leaf curl New Delhi virus is not seed-transmitted in melon

Transmission of plant viruses through seed can be one of the major factors contributing to long- distance dispersal through global trade of seeds and can have important ecological consequences for virus dissemination. Begomoviruses (genus Begomovirus, family Geminiviridae), and among them isolates of the species Tomato leaf curl New Delhi virus (ToLCNDV), cause significant yield losses in economically important crops worldwide. These viruses are horizontally transmitted in nature in a circulative and persistent manner by the whitefly Bemisia tabaci but in recent years several reports have raised the possibility of vertical transmission through seeds for some members of this genus. We have investigated the possible transmission by melon (Cucumis melo L.) seeds of a ToLCNDV isolate of the “Spain” strain, in three different melon cultivars (all susceptible to ToLCNDV). The presence of ToLCNDV in floral tissues and the detection of viral DNA in seeds reveals the seed-borne nature of this virus. However, grow-out studies conducted with the progeny of melon plants germinated from seeds collected from ToLCNDV-infected plants and evaluated at early (1 leaf) or at late (20 leaves) growth stages did not support the vertical transmission of ToLCNDV from seeds to the offspring.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

The begomovirus tomato leaf curl New Delhi virus is not seed-transmitted in melon

Transmission of plant viruses through seed can be one of the major factors contributing to longdistance dispersal through global trade of seeds and can have important ecological consequences for virus dissemination. Begomoviruses (genus Begomovirus, family Geminiviridae), and among them isolates of the species Tomato leaf curl New Delhi virus (ToLCNDV), cause significant yield losses in economically important crops worldwide. These viruses are horizontally transmitted in nature in a circulative and persistent manner by the whitefly Bemisia tabaci but in recent years several reports have raised the possibility of vertical transmission through seeds for some members of this genus. We have investigated the possible transmission by melon (Cucumis melo L.) seeds of a ToLCNDV isolate of the “Spain” strain, in three different melon cultivars (all susceptible to ToLCNDV). The presence of ToLCNDV in floral tissues and the detection of viral DNA in seeds reveals the seed-borne nature of this virus. However, grow-out studies conducted with the progeny of melon plants germinated from seeds collected from ToLCNDV-infected plants and evaluated at early (1 leaf) or at late (20 leaves) growth stages did not support the vertical transmission of ToLCNDV from seeds to the offspring.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Comparative assessment of consolidation treatments on archaeological fragments of roman cornices and islamic plasterwork

Los revestimientos arquitectónicos de origen arqueológico presentan una problemática de conservación y restauración bastante compleja, sobre todo en lo que a términos de consolidación se refiere. Con este trabajo se ofrecen distintos ensayos de consolidación (resina acrílica, silicato de etilo, butiral de polivinilo y carbonatogénesis bacteriana) que se han realizado en fragmentos de cornisas de cronología romana procedentes del Conjunto Arqueológico de Castulo en Linares (Jaén) y en yeserías medievales del Alcázar de Guadalajara. Los resultados obtenidos han permitido extraer conclusiones acerca de los aspectos positivos y negativos de los diversos tratamientos y de su viabilidad para la conservación de este tipo de decoraciones arquitectónicas.Conservation and restoration of architectural coatings of archaeological origin is a complex issue, especially as far as consolidation terms are concerned. This work presents different consolidation treatments (acrylic resin, ethyl silicate, polyvinyl butyral and bacterial carbonatogenesis) carried out on fragments of Roman chronology cornices from the Archaeological Complex Castulo, located in Linares (Jaén), and on original plasterwork from the Alcázar of Guadalajara. The results of the study showed the strengths and weaknesses of each treatment, allowing us to conclude their viability for the conservation of this type of architectural decorations

Universidad y sociedad: comunicación e integración en empresas e instituciones públicas y organizaciones no lucrativas

Depto. de Teorías y Análisis de la ComunicaciónFac. de Ciencias de la InformaciónFALSEsubmitte

INVENTARIO DE REGATAS COMO ATRACTIVO TURÍSTICO DE LA PROVINCIA DE LOS RÍOS

This study seeks to answer the question: What is the inventory of regattas in the province of Los Ríos? Where its main objective is to define that inventory of regattas as a tourist attraction in the province, through documentary and exploratory research, using the qualitative-inductive method through observation and interview techniques, for which the file was adapted for the survey. and hierarchy of tourist attractions of the MINTUR. As a result of this research work, it was possible to determine that there are 12 places where regattas are held in the province, located in 6 cantons, with 5 different types. Through this research, it is sought that the authorities use the information collected to establish a calendar and inform the population about the places where the regattas are held to improve tourism planning and, in turn, catalyze the economy of the province through the tourism.El presente estudio busca dar respuesta a la pregunta ¿Cuál es el inventario de regatas de la provincia de Los Ríos? Donde su objetivo principal es definir aquel inventario de regatas como atractivo turístico de la provincia, mediante la investigación documental y exploratoria, utilizando el método cualitativo-inductivo a través de las técnicas de observación y entrevista, para lo cual se adaptó la ficha para el levantamiento y jerarquización de atractivos turísticos del MINTUR. Como resultados de este trabajo de investigación se pudo determinar que existen 12 lugares donde se realizan las regatas en la provincia, ubicadas en 6 cantones, con 5 tipos diferentes. A través de esta investigación se procura que las autoridades utilicen la información recopilada para establecer un calendario y poner en conocimiento a la población sobre los lugares donde se efectúan las regatas para mejorar la planificación turística y a su vez lograr catalizar la economía de la provincia mediante el turismo

Importance of the dilution test in the dosage of coagulation factors XII and XI in plasma with positive lupus anticoagulant

Introduction. Thrombosis is associated with acquired risk factors or hypercoagulablestates. Antiphospholipid antibodies are found in infectious processes or associated with arterial or venous thrombosis. Among these is the lupus anticoagulant, which is conside-red an interference inhibitor because it prolongs phospholipid-dependent tests in vitro. Objectives. To relate the activity of factor XII and XI in patients with positive lupus anti-coagulant. Methodology. Of 55 plasmas, 34 met the inclusion criteria. Factors XII and XI were dosed by metric clot methods. Samples less than 50 Ul/dl are considered low factoractivity, to which the dilution test (parallelism) is performed. If a recovery greater than15% of the factor is evidenced, it is considered interference. If, on the contrary, the resultremains with little variation, it is confirmed. factor deficiency. Results. Of 34 dosages,79.4% (27/34) presented a decrease in factor XI. A dilution test was performed, and 100%recovery of factor XI was observed; Regarding the dosage of factor XII, 29.4% (10/34)presented values below 50 IU/dl and 70.6% (24/34) normal, did not recover in 22.2%(2/9) presenting deficit. Conclusions. The study of a prolonged PTT is carried out due tosuspicion of lupus anticoagulant or factor deficiency. The importance of the laboratory isthat every time a decreased coagulation factor is found, plasma dilution must be done todetermine if there is recovery of the factor or is a deficit of this.Introduction. Thrombosis is associated with acquired risk factors or hypercoagulable states. Antiphospholipid antibodies are found in infectious processes or associated with arterial or venous thrombosis. Among these is the lupus anticoagulant, which is conside- red an interference inhibitor because it prolongs phospholipid-dependent tests in vitro. Objectives. To relate the activity of factor XII and XI in patients with positive lupus anti- coagulant. Methodology. Of 55 plasmas, 34 met the inclusion criteria. Factors XII and XI were dosed by metric clot methods. Samples less than 50 Ul/dl are considered low factor activity, to which the dilution test (parallelism) is performed. If a recovery greater than 15% of the factor is evidenced, it is considered interference. If, on the contrary, the result remains with little variation, it is confirmed. factor deficiency. Results. Of 34 dosages, 79.4% (27/34) presented a decrease in factor XI. A dilution test was performed, and 100% recovery of factor XI was observed; Regarding the dosage of factor XII, 29.4% (10/34) presented values below 50 IU/dl and 70.6% (24/34) normal, did not recover in 22.2% (2/9) presenting deficit. Conclusions. The study of a prolonged PTT is carried out due to suspicion of lupus anticoagulant or factor deficiency. The importance of the laboratory is that every time a decreased coagulation factor is found, plasma dilution must be done to determine if there is recovery of the factor or is a deficit of this