EFFECT OF A SIX-WEEK NEUROMUSCULAR TRAINING PROGRAM ON VERTICAL STIFFNESS IN HEALTHY HIGH SCHOOL DISTANCE RUNNERS

Athletes, coaches, and health care teams know that preventing running-related injuries (RRI) and improving running performance are extremely important. Proactive neuromuscular training (NMT) is often included as a complement to running programs for this reason. The purpose of this study was to evaluate the effect of proactive six-week low-intensity NMT focused on proximal hip and thigh muscles on healthy high-school runners’ muscle strength, biomechanical stiffness, peak ground reaction force, cadence, and stride length. The study demonstrates that the NMT increased a runner’s total strength by 10.4% and knee extensor strength by 10.3%, showed no change in stiffness, cadence, or stride length, and showed a decrease in ground reaction force post-program by 1.3%. Results show the multivariable nature of RRI risk, and prompt further, more generalizable, evaluation

Use of Ar pellet ablation rate to estimate initial runaway electron seed population in DIII-D rapid shutdown experiments

Small (2-3 mm, 0.9-2 Pa • m3) argon pellets are used in the DIII-D tokamak to cause rapid shutdown (disruption) of discharges. The Ar pellet ablation is typically found to be much larger than expected from the thermal plasma electron temperature alone; the additional ablation is interpreted as being due to non-thermal runaway electrons (REs) formed during the pellet-induced temperature collapse. Simple estimates of the RE seed current using the enhanced ablation rate give values of order 1-10 kA, roughly consistent with estimates based on avalanche theory. Analytic estimates of the RE seed current based on the Dreicer formula tend to significantly underestimate it, while estimates based on the hot tail model significantly overestimate it

Can screening and brief intervention lead to population-level reductions in alcohol-related harm?

A distinction is made between the clinical and public health justifications for screening and brief intervention (SBI) against hazardous and harmful alcohol consumption. Early claims for a public health benefit of SBI derived from research on general medical practitioners' (GPs') advice on smoking cessation, but these claims have not been realized, mainly because GPs have not incorporated SBI into their routine practice. A recent modeling exercise estimated that, if all GPs in England screened every patient at their next consultation, 96% of the general population would be screened over 10 years, with 70-79% of excessive drinkers receiving brief interventions (BI); assuming a 10% success rate, this would probably amount to a population-level effect of SBI. Thus, a public health benefit for SBI presupposes widespread screening; but recent government policy in England favors targeted versus universal screening, and in Scotland screening is based on new registrations and clinical presentation. A recent proposal for a national screening program was rejected by the UK National Health Service's National Screening Committee because 1) there was no good evidence that SBI led to reductions in mortality or morbidity, and 2) a safe, simple, precise, and validated screening test was not available. Even in countries like Sweden and Finland, where expensive national programs to disseminate SBI have been implemented, only a minority of the population has been asked about drinking during health-care visits, and a minority of excessive drinkers has been advised to cut down. Although there has been research on the relationship between treatment for alcohol problems and population-level effects, there has been no such research for SBI, nor have there been experimental investigations of its relationship with population-level measures of alcohol-related harm. These are strongly recommended. In this article, conditions that would allow a population-level effect of SBI to occur are reviewed, including their political acceptability. It is tentatively concluded that widespread dissemination of SBI, without the implementation of alcohol control measures, might have indirect influences on levels of consumption and harm but would be unlikely on its own to result in public health benefits. However, if and when alcohol control measures were introduced, SBI would still have an important role in the battle against alcohol-related harm

Spatiotemporal Evolution of Runaway Electron Momentum Distributions in Tokamaks

Novel spatial, temporal, and energetically resolved measurements of bremsstrahlung hard-x-ray (HXR) emission from runaway electron (RE) populations in tokamaks reveal nonmonotonic RE distribution functions whose properties depend on the interplay of electric field acceleration with collisional and synchrotron damping. Measurements are consistent with theoretical predictions of momentum-space attractors that accumulate runaway electrons. RE distribution functions are measured to shift to a higher energy when the synchrotron force is reduced by decreasing the toroidal magnetic field strength. Increasing the collisional damping by increasing the electron density (at a fixed magnetic and electric field) reduces the energy of the nonmonotonic feature and reduces the HXR growth rate at all energies. Higher-energy HXR growth rates extrapolate to zero at the expected threshold electric field for RE sustainment, while low-energy REs are anomalously lost. The compilation of HXR emission from different sight lines into the plasma yields energy and pitch-angle-resolved RE distributions and demonstrates increasing pitch-angle and radial gradients with energy.United States. Department of Energy (DE-FC02-04ER54698)United States. Department of Energy (DE-FG02-07ER54917)United States. Department of Energy (DE-AC05-00OR22725)United States. Department of Energy (DE-FC02-99ER54512)United States. Department of Energy (DE-SC0016268

Chemotherapy alone for organ preservation in advanced laryngeal cancer

Background. For patients with advanced laryngeal cancer, a trial was designed to determine if chemotherapy alone, in patients achieving a complete histologic complete response after a single neoadjuvant cycle, was an effective treatment with less morbidity than concurrent chemoradiotherapy. Methods. Thirty-two patients with advanced laryngeal or hypopharyngeal cancer received 1 cycle of induction chemotherapy, and subsequent treatment was decided based on response. Results. A histologic complete response was achieved in 4 patients and were treated with chemotherapy alone. All 4 patients' cancer relapsed in the neck and required surgery and postoperative radiotherapy (RT). Twenty-five patients were treated with concomitant chemoradiation. Three patients were treated with surgery. Overall survival and disease-specific survival at 3 years were 68% and 78%, respectively. Conclusion. Chemotherapy alone is not feasible for long-term control of regional disease in patients with advanced laryngeal cancer even when they achieve a histologic complete response at the primary site. © 2009 Wiley Periodicals, Inc. Head Neck, 2010Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77508/1/21285_ftp.pd

Screening and brief interventions for hazardous and harmful alcohol use in primary care: a cluster randomised controlled trial protocol

A large number of randomised controlled trials in health settings have consistently reported positive effects of brief intervention in terms of reductions in alcohol use. However,although alcohol misuse is common amongst offenders, there is limited evidence of alcohol brief interventions in the criminal justice field. This factorial pragmatic cluster randomised controlledtrial with Offender Managers (OMs) as the unit of randomisation will evaluate the effectiveness and cost-effectiveness of different models of screening to identify hazardous and harmful drinkers in probation and different intensities of brief intervention to reduce excessive drinking in probation clients. Ninety-six OMs from 9 probation areas across 3 English regions (the NorthEast Region (n = 4) and London and the South East Regions (n = 5)) will be recruited. OMs will berandomly allocated to one of three intervention conditions: a client information leaflet control condition (n = 32 OMs); 5-minute simple structured advice (n = 32 OMs) and 20-minute brieflifestyle counselling delivered by an Alcohol Health Worker (n = 32 OMs). Randomisation will be stratified by probation area. To test the relative effectiveness of different screening methods all OMs will be randomised to either the Modified Single Item Screening Questionnaire (M-SASQ) orthe Fast Alcohol Screening Test (FAST). There will be a minimum of 480 clients recruited into the trial. There will be an intention to treat analysis of study outcomes at 6 and 12 months postintervention. Analysis will include client measures (screening result, weekly alcohol consumption,alcohol-related problems, re-offending, public service use and quality of life) and implementation measures from OMs (the extent of screening and brief intervention beyond the minimum recruitment threshold will provide data on acceptability and feasibility of different models of brief intervention). We will also examine the practitioner and organisational factors associated with successful implementation.The trial will evaluate the impact of screening and brief alcohol intervention in routine probation work and therefore its findings will be highly relevant to probation teams and thus the criminal justice system in the UK

Spatio-temporal variations in seasonal ice tongue submarine melt rate at a tidewater glacier in southwest Greenland

Submarine melting of tidewater glaciers is proposed as a trigger for their recent thinning, acceleration and retreat. We estimate spring submarine melt rates (SMRs) of Kangiata Nunaata Sermia in southwest Greenland, from 2012 to 2014, by examining changes in along-fjord freeboard and velocity of the seasonal floating ice tongue. Estimated SMRs vary spatially and temporally near the grounding line, with mean rates of 1.3 ± 0.6, 0.8 ± 0.3 and 1.0 ± 0.4 m d−1 across the tongue in 2012, 2013 and 2014, respectively. Higher melt rates correspond with locations of emerging subglacial plumes and terminus calving activity observed during the melt season using time-lapse camera imagery. Modelling of subglacial flow paths suggests a dynamic system capable of rapid re-routing of subglacial discharge both within and between melt seasons. Our results provide an empirically-derived link between the presence of subglacial discharge plumes and areas of high spring submarine melting and calving along glacier termini

Metamorphosis of plasma turbulence-shear flow dynamics through a transcritical bifurcation

The structural properties of an economical model for a confined plasma turbulence governor are investigated through bifurcation and stability analyses. A close relationship is demonstrated between the underlying bifurcation framework of the model and typical behavior associated with low- to high-confinement transitions such as shear flow stabilization of turbulence and oscillatory collective action. In particular, the analysis evinces two types of discontinuous transition that are qualitatively distinct. One involves classical hysteresis, governed by viscous dissipation. The other is intrinsically oscillatory and non-hysteretic, and thus provides a model for the so-called dithering transitions that are frequently observed. This metamorphosis, or transformation, of the system dynamics is an important late side-effect of symmetry-breaking, which manifests as an unusual non-symmetric transcritical bifurcation induced by a significant shear flow drive.Comment: 17 pages, revtex text, 9 figures comprised of 16 postscript files. Submitted to Phys. Rev.