114 research outputs found
Phase I trial and pharmacokinetic study of tanibirumab, a fully human monoclonal antibody to vascular endothelial growth factor receptor 2, in patients with refractory solid tumors
Personal factors associated with health-related quality of life in persons with morbid obesity on treatment waiting lists in Norway
Purpose To explore relationships of socio-demographic
variables, health behaviours, environmental characteristics
and personal factors, with physical and mental health
variables in persons with morbid obesity, and to compare
their health-related quality of life (HRQoL) scores with
scores from the general population.
Methods A cross-sectional correlation study design was
used. Data were collected by self-reported questionnaire
from adult patients within the first 2 days of commencement
of a mandatory educational course. Of 185 course
attendees, 142 (76.8%) volunteered to participate in the
study. Valid responses on all items were recorded for 128
participants. HRQoL was measured with the Short Form
12v2 from which physical (PCS) and mental component
summary (MCS) scores were computed. Other standardized
instruments measured regular physical activity, social
support, self-esteem, sense of coherence, self-efficacy and
coping style.
Results Respondents scored lower on all the HRQoL subdomains
compared with norms. Linear regression analyses
showed that personal factors that included self-esteem,
self-efficacy, sense of coherence and coping style
explained 3.6% of the variance in PCS scores and 41.6% in
MCS scores.
Conclusion Personal factors such as self-esteem, sense of
coherence and a high approaching coping style are strongly
related to mental health in obese persons
Qualidade de vida após revascularização do miocárdio: avaliação segundo duas perspectivas metodológicas
Utilização da versão adaptada da escala de qualidade de vida de Flanagan em pacientes cardíacos
Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy
Circulating biomarkers and outcome from a randomised phase II trial of sunitinib vs everolimus for patients with metastatic renal cell carcinoma
Inhibition des VEGF- Rezeptorsystems mit Tyrosinkinase-Inhibitoren. Angiogenese-Inhibition in der Onkologie
Dendritic Cell Vaccines Presenting Autologous Tumor Antigens from Self-renewing Cancer Cells in Metastatic Renal Cell Carcinoma
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