220 research outputs found
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Are you talking to me? An analysis of journalism conversation on social media
Social media has become a key medium for discussion and dissemination of news stories, fuelled by the low barrier to entry and the ease of interaction. News stories may be propagated through these networks either by official news organisation accounts, by individual journalists or by members of the public, through link sharing, endorsing or commenting. This preliminary research aims to show how computational analysis of large-scale data-sets allows us to investigate the means by which news stories are spread through social media, and how the conversation around them is shaped by journalists and news organisations. Through the capture of more than 11 million tweets relating to 2303 Twitter accounts connected to journalism and news organisations, we are able to analyse the conversation within and around journalism, examining who spreads information about news articles and who interacts in the discussion around them. Capturing the tweets of news organisations and journalists and the replies and retweets of these micro-blogs allows us to build a rich picture of interaction around news media
Smad signalling in the ovary
has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta) superfamily. In the ovary, several TGFbeta superfamily members are expressed by the oocyte, granulosa and thecal cells at different stages of folliculogenesis, and they signal mainly through two different Smad pathways in an autocrine/paracrine manner. Defects in the upstream signalling cascade molecules, the ligands and receptors, are known to have adverse effects on ovarian organogenesis and folliculogenesis, but the role of the individual Smad proteins in the proper function of the ovary is just beginning to be understood for example through the use of Smad knockout models. Although most of the different Smad knockouts are embryonic lethal, it is known, however, that in Smad1 and Smad5 knockout mice primordial germ cell development is impaired and that Smad3 deficient mice harbouring a deletion in exon 8 exhibit impaired folliculogenesis and reduced fertility. In this minireview we discuss the role of Smad structure and function in the ovarian context.has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta) superfamily. In the ovary, several TGFbeta superfamily members are expressed by the oocyte, granulosa and thecal cells at different stages of folliculogenesis, and they signal mainly through two different Smad pathways in an autocrine/paracrine manner. Defects in the upstream signalling cascade molecules, the ligands and receptors, are known to have adverse effects on ovarian organogenesis and folliculogenesis, but the role of the individual Smad proteins in the proper function of the ovary is just beginning to be understood for example through the use of Smad knockout models. Although most of the different Smad knockouts are embryonic lethal, it is known, however, that in Smad1 and Smad5 knockout mice primordial germ cell development is impaired and that Smad3 deficient mice harbouring a deletion in exon 8 exhibit impaired folliculogenesis and reduced fertility. In this minireview we discuss the role of Smad structure and function in the ovarian context.has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta) superfamily. In the ovary, several TGFbeta superfamily members are expressed by the oocyte, granulosa and thecal cells at different stages of folliculogenesis, and they signal mainly through two different Smad pathways in an autocrine/paracrine manner. Defects in the upstream signalling cascade molecules, the ligands and receptors, are known to have adverse effects on ovarian organogenesis and folliculogenesis, but the role of the individual Smad proteins in the proper function of the ovary is just beginning to be understood for example through the use of Smad knockout models. Although most of the different Smad knockouts are embryonic lethal, it is known, however, that in Smad1 and Smad5 knockout mice primordial germ cell development is impaired and that Smad3 deficient mice harbouring a deletion in exon 8 exhibit impaired folliculogenesis and reduced fertility. In this minireview we discuss the role of Smad structure and function in the ovarian context.Peer reviewe
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‘Racist behaviour is interfering with the game’: exploring football fans’ online responses to accusations of racism in football
This paper explores an incident of alleged fan racism involving Chelsea defender, Antonio Rüdiger. During a match against Tottenham Hotspur, in December 2019, Rüdiger claimed he heard racial abuse from Spurs fans. This incident sparked a broader national conversation regarding racism in sport, and wider society. This paper will draw on a comprehensive content analysis of Twitter comments to provide insights into fan reactions at the time of the incident. Was Rüdiger alleged to have played the ‘race card’? Was Rüdiger believed to have used his ‘race’ to attempt to punish the Spurs’ fans? Using thematic analysis, it will highlight patterns in fan responses to this case and attempt to illustrate football fans’ attitudes towards ‘race’ and racism within English football. The paper will close by offering some final thoughts on how racism, and other forms of discrimination, can be both challenged inside the stadium and on social media
A Computer Vision-Based Approach for Non-contact Modal Analysis and Finite Element Model Updating
Computer vision-based techniques for modal analysis and system identification are rapidly becoming of great interest for both academic research and engineering practice in structural engineering. For instance, this is particularly relevant in fields such as bridge or tall building monitoring, where the large size of the structure would require an expensive sensor network, and for the characterisation of very slender, highly-flexible structural components, where physically-attached sensors cannot be deployed without altering the mass and stiffness of the system under investigation. This study concerns the latter case. Here, an algorithm for the full-field, non-contact extraction and processing of useful information from vibrational data is applied. Firstly, video acquisition is used to capture rapidly very spatially- and temporally-dense information regarding the vibrational behaviour of a high-aspect-ratio (HAR) prototype wing, with high image quality and high frame rate. Video processing is then applied to extract displacement time histories from the collected data; in turn, these are used to perform Modal Analysis (MA) and Finite Element Model Updating (FEMU). Results are benchmarked against the ones obtained from a single-point laser Doppler vibrometer (LDV). The study is performed on the beam-like spar of the wing prototype with and without the sensors attached to appreciate the disruptive effects of sensor loading. Promising results were achieved
Investigating Online Fan Responses to the Rooney Rule in English Football
Purpose
This work critically investigates online fan responses towards the implementation of the affirmative action policy, the Rooney Rule, within English professional football. It explores systemic and structural racism and the history of the Rooney Rule, before analysing football fans' Twitter comments concerning the policy within English football across an 18-month period.
Design/methodology/approach
This research utilised a bespoke search programme to identify and analyse Tweets which focused on the Rooney Rule in English football. A total of 205 posts were thematically analysed and a series of codes were created.
Findings
The findings illustrated that fans were generally divided over the Rooney Rule. Over half of the participants welcomed counter measures against structural racism although many caveated responses by critiquing the Rule's approach and scope. For others, however, the policy is yet another example of ‘reverse racism’ and ‘political correctness gone mad’. The findings illustrate that there is an undercurrent of hostility towards anti-racist action and a belief that sport is inherently meritocratic and fair.
Originality/value
While much research has focused on examining online reactions to ‘trigger events’, this chapter provides an empirical insight into contemporary football fan responses towards anti-racist action in the ‘beautiful game’. It demonstrates that there are a series of common misconceptions and misunderstandings towards affirmative action policies in sport. Once we become aware of such misunderstandings, we can attempt to remedy them in order to aid the efficacy of anti-racist action
Two-Loop Quantum Corrections of Scalar QED with Non-Minimal Chern-Simons Coupling
We investigate two-loop quantum corrections to non-minimally coupled
Maxwell-Chern-Simons theory. The non-minimal gauge interaction represents the
magnetic moment interaction between the charged scalar and the electromagnetic
field. We show that the one-loop renormalizability of the theory found in
previous work does not survive to the two-loop level. However, with an
appropriate choice of the non-minimal coupling constant, it is possible to
renormalize the two-loop effective potential and hence render it potentially
useful for a detailed analysis of spontaneous symmetry breaking induced by
radiative corrections.Comment: 29 pages, including 21 figures. One author added, some formulae
corrected and references adde
Intimate Partner Violence and Abuse Against Men: Voices of Victimization Among Ex-Servicemen of the British Armed Forces
This study presents the personal testimonies of male British ex-Armed Forces personnel who have experienced violence and abuse victimization that was perpetrated by civilian female partners. In this research, we argue that to embark upon any understanding of the domestic lives of military personnel, an appreciation of the linkages to the cultural context of the military institution is necessary. Understanding the influence of the military institution beyond the military domain is crucial. We unveil the nature and character of the violence and abuse and how the servicemen negotiated their relationships. In doing so, we highlight the embodiment of military discipline, skills, and tactics in the home—not ones of violence which may be routinely linked to military masculinities; rather ones of restraint, tolerance, stoicism, and the reduction of a threat to inconsequential individual significance
Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells
Orientador: Iverson LadewigMonografia (licenciatura) - Universidade Federal do Paraná. Setor de Ciências Biológicas. Curso de Educação FÃsica
Amphiregulin cooperates with bone morphogenetic protein 15 to increase oocyte developmental competence by gap junction-mediated enhanced metabolite supply
This study assessed the participation of amphiregulin (AREG) and bone morphogenetic protein 15 (BMP15) during maturation of bovine cumulus oocyte complexes (COCs) on cumulus cell function and their impact on subsequent embryo development. AREG treatment of COCs enhanced blastocyst formation and quality only when in the presence of BMP15. Expression of hyaluronan synthase 2 was enhanced by follicle stimulating hormone (FSH) but not by AREG, which was reflected in the level of cumulus expansion. Although both FSH and AREG stimulated glycolysis, AREG treated COCs had higher glucose consumption, lactate production and ratio of lactate production to glucose uptake. Autofluorescence levels in oocytes, indicative of NAD(P)H and FAD++, were increased with combined AREG and BMP15 treatment of COCs. In contrast, these treatments did not alter autoflouresence levels when cumulus cells were removed from oocytes, even in the presence of other COCs, suggesting oocyte-cumulus gap-junctional communication (GJC) is required. FSH contributed to maintaining GJC for an extended period of time. Remarkably, BMP15 was equally effective at maintaining GJC even in the presence of AREG. Hence, AREG stimulation of COC glycolysis and BMP15 preservation of GJC may facilitate efficient transfer of metabolites from cumulus cells to the oocyte thereby enhancing oocyte developmental competence. These results have implications for improving in vitro oocyte maturation systems.Satoshi Sugimura, Lesley J Ritter, Melanie L Sutton-McDowall, David G Mottershead, Jeremy G Thompson and Robert B Gilchris
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