Enhancing the mechanical properties and formability of low carbon steel with dual-phase microstructures

In the present study, a special heat treatment cycle (step quenching) was used to produce a dual-phase (DP) microstructure in low carbon steel. By producing this DP microstructure, the mechanical properties of the investigated steel such as yield stress, tensile strength, and Vickers hardness were increased 14, 55, and 38%, respectively. In order to investigate the effect of heat treatment on formability of the steel, Nakazima forming test was applied and subsequently finite element base modeling was used to predict the outcome on forming limit diagrams. The results show that the DP microstructure also has a positive effect on formability. The results of finite element simulations are in a good agreement with those obtained by the experimental test

The Index Prediction of Tehran Stock Exchange by Combining the Principal Components Analysis, Support Vector Regression and Particle Swarm Optimization

The prediction of future fluctuations in stock index can provide information about the future trend in the capital market. In order to increase the accuracy of the prediction of stock exchange index, this study used a combination of statistical methods and artificial intelligence. In this study, a hybrid stock index prediction model by utilizing principal component analysis (PCA), support vector regression (SVR) and particle swarm optimization (PSO) is proposed. In the proposed model, first, the PCA is used to deal with the nonlinearity property of the stock index data. The proposed model utilizes PCA to extract features from the observed stock index data. The features which can be used to represent underlying/hidden information of the data are then served as the inputs of SVR to build the stock index prediction model. Finally, PSO is applied to optimize the parameters of the SVR prediction model since the parameters of SVR must be carefully selected in establishing an effective and efficient SVR model. The findings show that preprocessing the data can decrease the prediction error of the model significantly

An efficient method for synthesis of stable phosphorus ylides and 1,4-diionic organophosphorus compounds in the presence of sodium dodecyl sulfate in aqueous media

AbstractStable crystalline phosphorus ylides and 1,4-diionic organophosphorus compounds were obtained in good to excellent yields from the 1:1:1 addition reaction between triphenylphosphine, dialkyl acetylenedicarboxylates and β-dicarbonyl or heterocyclic compounds, such as diethyl malonate, acetyl acetone, 1,3-diphenyl propane-1,3-dione, 1,3-dimethylbarbituric acid, meldrum’s acid, 2-benzoxazolinone, benzotirazole, and 2-thiazoline-2-thiol in the presence of sodium dodecyl sulfate as a surfactant in water. Green synthesis, mild conditions, decreasing timescale of reaction, low cost, and easy workup are the main advantages of this method

On the wave propagation of the multi-scale hybrid nanocomposite doubly curved viscoelastic panel

In this paper, wave propagation analysis of multi-hybrid nanocomposite (MHC) reinforced doubly curved panel embedded in the viscoelastic foundation is carried out. Higher-order shear deformable theory (HSDT) is utilized to express the displacement kinematics. The rule of mixture and modified Halpin–Tsai model are engaged to provide the effective material constant of the MHC reinforced doubly curved panel. By employing Hamilton’s principle, the governing equations of the structure are derived and solved with the aid of an analytical method. Afterward, a parametric study is carried out to investigate the effects of the viscoelastic foundation, carbon nanotubes’ (CNTs’) weight fraction, various MHC patterns, radius to total thickness ratio, and carbon fibers angel on the phase velocity of the MHC reinforced doubly curved panel in the viscoelastic medium. The results show that, by considering the viscous parameter, the relation between wavenumber and phase velocity changes from exponential increase to logarithmic boost. A useful suggestion of this research is that the effects of fiber angel and damping parameter on the phase velocity of a doubly curved panel are hardly dependent on the wavenumber. The presented study outputs can be used in ultrasonic inspection techniques and structural health monitoring.publishe

Discrepancy between mRNA and Protein Expression of Neutrophil Gelatinase-Associated Lipocalin in Bronchial Epithelium Induced by Sulfur Mustard

Sulfur mustard (SM) is a potent vesicant that has been employed as a chemical weapon in various conflicts during the 20th century. More recently, mustard was used in the Iraq conflict against Iranian troops and civilians. At the present time there are more than 40.000 people suffering from pulmonary lesions special bronchiolitis obliterans (BOs) due to mustard gas. SM increases the endogenous production of reactive oxygen species (ROS). Neutrophil Gelatinase-associated Lipocalin 2 (Lcn2, NGAL) is a member of the lipocalin superfamily for which a variety of functions such as cellular protection against oxidative stress have been reported. Ten normal and Twenty SM-induced COPD patient individuals were studied. Assessment of NGAL expressions in healthy and the patients endobrinchial biopsies were performed by semiquantitative RT-PCR, real-time RT-PCR, and Immunohistochemistry analysis. While Normal control samples expressed same level of mRNA NGAL, expression level of mRNA-NGAL was upregulated about 1.4- to 9.8-folds compared to normal samples. No significant immunoreactivity was revealed in both samples. As we are aware this is the first report of induction of NGAL in patients exposed to SM. NGAL may play an important role in cellular protection against oxidative stress toxicity induced by mustard gas in airway wall of patients

HO1 mRNA and Protein do not Change in Parallel in Bronchial Biopsies of Patients After Long Term Exposure to Sulfur Mustard

Sulfur mustard (SM), is an alkylating agent and has been emerged as a chemical weapon in various battlefields. More recently, SM was employed in the Iraq conflict against Iranian military forces and civilians. Nowadays there are more than 40,000 people suffering from pulmonary lesions special chronic obstructive pulmonary disease (COPD) due to mustard gas in Iran. SM causes the endogenous production of reactive oxygen species (ROS)

Structural effects of different NH-acids and dialkyl acetylenedicarboxylates on the kinetic parameters of stable phosphorus ylids: a mechanistic investigation

Kinetic studies were made of the reactions between triphenylphosphine 1 and dialkyl acetylenedicarboxylates 2, in the presence of NH-acids, such as benzotriazole, 5-methylbenzotriazole or 5-chlorobenzotriazole 3 (as a protic/nucleophilic reagent). To determine the kinetic parameters of the reactions, they were monitored by UV spectrophotometry. Useful information was obtained from studies of the effect of solvent, structure of reactants (dialkyl acetylenedicarboxylates and NH-acids) and also concentration of reactants on the reaction rates. First and third steps (k 2 , k 3 ) of all reactions were recognized as a rate determining and fast steps, respectively. Proposed mechanism was confirmed on the basis of experimental data

International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS