5,376 research outputs found
The effects of graded motor imagery and its components on chronic pain: A systematic review and meta-analysis
This is the post-print version of the final paper published in The Journal of Pain. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 The American Pain Society.Graded motor imagery (GMI) is becoming increasingly used in the treatment of chronic pain conditions. The objective of this systematic review was to synthesize all evidence concerning the effects of GMI and its constituent components on chronic pain. Systematic searches were conducted in 10 electronic databases. All randomized controlled trials (RCTs) of GMI, left/right judgment training, motor imagery, and mirror therapy used as a treatment for chronic pain were included. Methodological quality was assessed using the Cochrane risk of bias tool. Six RCTs met our inclusion criteria, and the methodological quality was generally low. No effect was seen for left/right judgment training, and conflicting results were found for motor imagery used as stand-alone techniques, but positive effects were observed for both mirror therapy and GMI. A meta-analysis of GMI versus usual physiotherapy care favored GMI in reducing pain (2 studies, n = 63; effect size, 1.06 [95% confidence interval, .41, 1.71]; heterogeneity, I2 = 15%). Our results suggest that GMI and mirror therapy alone may be effective, although this conclusion is based on limited evidence. Further rigorous studies are needed to investigate the effects of GMI and its components on a wider chronic pain population.NHMR
The Long-term Coercive Effect of State Community Benefit Laws on Hospital Community Health Orientation
This study is an examination of the long-term coercive effect of state community benefit laws (CB Laws) on the provision of community health activities in U.S. acute care hospitals. The sample included all the not-for-profit and investor owned acute care hospitals for which 1994 and 2006 AHA Annual Survey data were available. A panel design was used to longitudinally examine the effect that state CB Laws had on hospital community health orientation activities and the provision of health promotion services, after controlling for the influence of other organizational and environmental variables that might affect these activities and services. The authors found that both CB Law state and non CB Law state hospitals increased their number of orientation activities and promotion services from 1994 to 2006. However, there was no significant difference in the gains in these activities and services between these two groups of hospitals. These results suggest that other environmental and organizational factors may mediate the effect of the state CB Laws over time
Demonstrating the negligible contribution of optical ACS/HST galaxies to source-subtracted cosmic infrared background fluctuations in deep IRAC/Spitzer images
We study the possible contribution of optical galaxies detected with the {\it
Hubble} ACS instrument to the near-IR cosmic infrared (CIB) fluctuations in
deep {\it Spitzer} images. The {\it Spitzer} data used in this analysis are
obtained in the course of the GOODS project from which we select four
independent regions observed at both 3.6 and 4.5
\um. ACS source catalogs for all of these areas are used to construct maps
containing only their emissions in the ACS -bands. We find that
deep Spitzer data exhibit CIB fluctuations remaining after removal of
foreground galaxies of a very different clustering pattern at both 3.6 and 4.5
\um than the ACS galaxies could contribute. We also find that there are very
good correlations between the ACS galaxies and the {\it removed} galaxies in
the Spitzer maps, but practically no correlations remain with the residual
Spitzer maps used to identify the CIB fluctuations. These contributions become
negligible on larger scales used to probe the CIB fluctuations arising from
clustering. This means that the ACS galaxies cannot contribute to the
large-scale CIB fluctuations found in the residual Spitzer data. The absence of
their contributions also means that the CIB fluctuations arise at z\gsim 7.5
as the Lyman break of their sources must be redshifted past the longest ACS
band, or the fluctuations have to originate in the more local but extremely low
luminosity galaxies.Comment: Ap.J.Letters, in press. Minor revisions to mathc the accepted versio
Wind-tunnel investigation of the aerodynamic pressures on the Apollo command module configuration
Wind tunnel study of aerodynamic pressures on Apollo command module configuratio
Calibrating Array Detectors
The development of sensitive large format imaging arrays for the infrared
promises to provide revolutionary capabilities for space astronomy. For
example, the Infrared Array Camera (IRAC) on SIRTF will use four 256 x 256
arrays to provide background limited high spatial resolution images of the sky
in the 3 to 8 micron spectral region. In order to reach the performance limits
possible with this generation of sensitive detectors, calibration procedures
must be developed so that uncertainties in detector calibration will always be
dominated by photon statistics from the dark sky as a major system noise
source. In the near infrared, where the faint extragalactic sky is observed
through the scattered and reemitted zodiacal light from our solar system,
calibration is particularly important. Faint sources must be detected on this
brighter local foreground.
We present a procedure for calibrating imaging systems and analyzing such
data. In our approach, by proper choice of observing strategy, information
about detector parameters is encoded in the sky measurements. Proper analysis
allows us to simultaneously solve for sky brightness and detector parameters,
and provides accurate formal error estimates.
This approach allows us to extract the calibration from the observations
themselves; little or no additional information is necessary to allow full
interpretation of the data. Further, this approach allows refinement and
verification of detector parameters during the mission, and thus does not
depend on a priori knowledge of the system or ground calibration for
interpretation of images.Comment: Scheduled for ApJS, June 2000 (16 pages, 3 JPEG figures
New measurements of cosmic infrared background fluctuations from early epochs
Cosmic infrared background fluctuations may contain measurable contribution
from objects inaccessible to current telescopic studies, such as the first
stars and other luminous objects in the first Gyr of the Universe's evolution.
In an attempt to uncover this contribution we have analyzed the GOODS data
obtained with the Spitzer IRAC instrument, which are deeper and cover larger
scales than the Spitzer data we have previously analyzed. Here we report these
new measurements of the cosmic infrared background (CIB) fluctuations remaining
after removing cosmic sources to fainter levels than before. The remaining
anisotropies on scales > 0.5 arcmin have a significant clustering component
with a low shot-noise contribution. We show that these fluctuations cannot be
accounted for by instrumental effects, nor by the Solar system and Galactic
foreground emissions and must arise from extragalactic sources.Comment: Ap.J.Letters, in pres
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Interventions for treating pain and disability in adults with complex regional pain syndrome - An overview of systematic reviews
This article is available open access through the publisher’s website at the link below. Copyright © 2013 The Cochrane Collaboration.Background - There is currently no strong consensus regarding the optimal management of complex regional pain syndrome although a multitude of interventions have been described and are commonly used.
Objectives - To summarise the evidence from Cochrane and non-Cochrane systematic reviews of the effectiveness of any therapeutic intervention used to reduce pain, disability or both in adults with complex regional pain syndrome (CRPS).
Methods - We identified Cochrane reviews and non-Cochrane reviews through a systematic search of the following databases: Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (DARE), Ovid MEDLINE, Ovid EMBASE, CINAHL, LILACS and PEDro. We included non-Cochrane systematic reviews where they contained evidence not covered by identified Cochrane reviews. The methodological quality of reviews was assessed using the AMSTAR tool. We extracted data for the primary outcomes pain, disability and adverse events, and the secondary outcomes of quality of life, emotional well being and participants' ratings of satisfaction or improvement. Only evidence arising from randomised controlled trials was considered. We used the GRADE system to assess the quality of evidence.
Main results - We included six Cochrane reviews and 13 non-Cochrane systematic reviews. Cochrane reviews demonstrated better methodological quality than non-Cochrane reviews. Trials were typically small and the quality variable.
There is moderate quality evidence that intravenous regional blockade with guanethidine is not effective in CRPS and that the procedure appears to be associated with the risk of significant adverse events.
There is low quality evidence that bisphosphonates, calcitonin or a daily course of intravenous ketamine may be effective for pain when compared with placebo; graded motor imagery may be effective for pain and function when compared with usual care; and that mirror therapy may be effective for pain in post-stroke CRPS compared with a 'covered mirror' control. This evidence should be interpreted with caution. There is low quality evidence that local anaesthetic sympathetic blockade is not effective. Low quality evidence suggests that physiotherapy or occupational therapy are associated with small positive effects that are unlikely to be clinically important at one year follow up when compared with a social work passive attention control.
For a wide range of other interventions, there is either no evidence or very low quality evidence available from which no conclusions should be drawn.
Authors' conclusions - There is a critical lack of high quality evidence for the effectiveness of most therapies for CRPS. Until further larger trials are undertaken, formulating an evidence-based approach to managing CRPS will remain difficult
Interacting bosons in an optical lattice: Bose-Einstein condensates and Mott insulator
A dense Bose gas with hard-core interaction is considered in an optical
lattice. We study the phase diagram in terms of a special mean-field theory
that describes a Bose-Einstein condensate and a Mott insulator with a single
particle per lattice site for zero as well as for non-zero temperatures. We
calculate the densities, the excitation spectrum and the static structure
factor for each of these phases.Comment: 17 pages, 5 figures; 1 figure added, typos remove
Cosmic Infrared Background Fluctuations and Zodiacal Light
We have performed a specific observational test to measure the effect that
the zodiacal light can have on measurements of the spatial fluctuations of the
near-IR background. Previous estimates of possible fluctuations caused by
zodiacal light have often been extrapolated from observations of the thermal
emission at longer wavelengths and low angular resolution, or from IRAC
observations of high latitude fields where zodiacal light is faint and not
strongly varying with time. The new observations analyzed here target the
COSMOS field, at low ecliptic latitude where the zodiacal light intensity
varies by factors of over the range of solar elongations at which the
field can be observed. We find that the white noise component of the spatial
power spectrum of the background is correlated with the modeled zodiacal light
intensity. Roughly half of the measured white noise is correlated with the
zodiacal light, but a more detailed interpretation of the white noise is
hampered by systematic uncertainties that are evident in the zodiacal light
model. At large angular scales () where excess power above the
white noise is observed, we find no correlation of the power with the modeled
intensity of the zodiacal light. This test clearly indicates that the large
scale power in the infrared background is not being caused by the zodiacal
light.Comment: 17 pp. Accepted for publication in the Ap
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