A critical biography of Rosalie van der Gucht : investigating her contribution to education in South Africa with special reference to speech and drama

Bibliography: pages 279-292.This study attempts to explore the ways in which Rosalie Van der Gucht influenced and contributed to Speech and Drama education during the second half of this century in the Cape. The writer takes the view that although Van der Gucht was not particularly original in her work - dramatically, socially or politically - she had an impact which is still felt in the Cape Province and beyond, because of her outstanding qualities as a leader, teacher and play director; effected through her special skills as a communicator. The chosen form is a critical biography, which makes it possible to investigate the impact of Van der Gucht's initiatives within the contemporary context. Given that there are only a handful of books which deal with the theatre of this period in the Cape, and they contain few specific references to Van der Gucht; the chief sources for this topic were unpublished written material, and interviews with Van der Gucht's past students, colleagues, friends and relations. Of special importance were Van der Gucht's unsorted collection of papers (bequeathed to the Human Sciences Research Council), the Little Theatre Press Cutting books and the University of Cape Town Archives. In Chapter One the formative influence of her parents, her education, and her first working years in England prior to the Second World War are traced. The following six chapters cover, decade by decade, the period from 1942 to 1971 when Van der Gucht was at the University of Cape Town, training aspirant Speech and Drama teachers, actors, and students taking general Arts degrees. Her influence upon the teacher and actor training courses, including a scrutiny of curriculum developments, is examined; as is her membership of the South African Guild of Speech Teachers and her foundation and leadership of Theatre for Youth which aimed to reach young people beyond the University. Chapter 8 covers the years after her retirement from the University, when she launched upon a second career as a play director, and attempts to pinpoint the chief characteristics of her directing. Chapter 9 deals with the events leading to her death in 1985 - which shed new light on Van der Gucht as a person. The conclusions drawn from this study pertain to Van der Gucht's quality as a person and teacher. The writer takes the paradoxical view that this woman of British origin and education; was, first and foremost, an educator of the traditional kind found in Africa: an oral educator, who used oral material, verbal communication and social situations to inspire and direct those with whom she worked to greater efforts for the benefit of their society, themselves and the discipline of drama. The study is intended to be a useful historical resource for students of drama and the theatre in South Africa

Transmission of Tetracapsuloides bryosalmonae (Myxozoa: Malacosporea), the causative organism of salmonid proliferative kidney disease, to the freshwater bryozoan Fredericella sultana

Proliferative kidney disease (PKD), caused by the malacosporean parasite Tetracapsuloides bryosalmonae, causes significant losses among salmonids in Western Europe and North America. The role of salmonid fish in the life-cycle of this parasite has been conjectured upon for over a quarter of a century. To examine whether fish can transmit the infection to bryozoans, the known invertebrate host, water containing parasitized brown trout Salmo trutta was pumped into tanks containing colonies of Fredericella sultana collected from the wild. The specific parasite-free status of these colonies being first assessed, by PCR and prolonged laboratory culture. After 6 weeks exposure to the brown trout aquarium effluent, portions of these colonies displayed overt infections with T. bryosalmonae. This was in contrast to control bryozoans, derived from the experimental colonies prior to exposure, which remained T. bryosalmonae negative. In addition, spores obtained from the experimentally infected colonies were exposed to naive rainbow trout, resulting in clinical PKD, thus completing a cycle of transmission. During the experiments, the infection was noted to inhibit statoblast formation within bryozoans and appeared to be pathogenic, finally killing the bryozoan host. These findings indicate that fish can transmit the parasite to bryozoans and are an integral part of this parasite’s life-cycle

The impact of targeting TRAF2 and NCK-interacting protein kinase (TNIK) on anti-tumor effect in small cell lung cancer

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Athena MIMOS II Mossbauer spectrometer investigation

Mössbauer spectroscopy is a powerful tool for quantitative mineralogical analysis of Fe-bearing materials. The miniature Mössbauer spectrometer MIMOS II is a component of the Athena science payload launched to Mars in 2003 on both Mars Exploration Rover missions. The instrument has two major components: (1) a rover-based electronics board that contains power supplies, a dedicated central processing unit, memory, and associated support electronics and (2) a sensor head that is mounted at the end of the instrument deployment device (IDD) for placement of the instrument in physical contact with soil and rock. The velocity transducer operates at a nominal frequency of 25 Hz and is equipped with two 57Co/Rh Mössbauer sources. The reference source (5 mCi landed intensity), reference target (alpha-Fe2O3 plus alpha-Fe0), and PIN-diode detector are configured in transmission geometry and are internal to the instrument and used for its calibration. The analysis Mössbauer source (150 mCi landed intensity) irradiates Martian surface materials with a beam diameter of 1.4 cm. The backscatter radiation is measured by four PIN-diode detectors. Physical contact with surface materials is sensed with a switch-activated contact plate. The contact plate and reference target are instrumented with temperature sensors. Assuming 18% Fe for Martian surface materials, experiment time is 6–12 hours during the night for quality spectra (i.e., good counting statistics); 1–2 hours is sufficient to identify and quantify the most abundant Fe-bearing phases. Data stored internal to the instrument for selectable return to Earth include Mössbauer and pulse-height analysis spectra (512 and 256 channels, respectively) for each of the five detectors in up to 13 temperature intervals (65 Mössbauer spectra), engineering data for the velocity transducer, and temperature measurements. The total data volume is 150 kB. The mass and power consumption are 500 g (400 g for the sensor head) and 2 W, respectively. The scientific measurement objectives of the Mössbauer investigation are to obtain for rock, soil, and dust (1) the mineralogical identification of iron-bearing phases (e.g., oxides, silicates, sulfides, sulfates, and carbonates), (2) the quantitative measurement of the distribution of iron among these iron-bearing phases (e.g., the relative proportions of iron in olivine, pyroxenes, ilmenite, and magnetite in a basalt), (3) the quantitative measurement of the distribution of iron among its oxidation states (e.g., Fe2+, Fe3+, and Fe6+), and (4) the characterization of the size distribution of magnetic particles. Special geologic targets of the Mössbauer investigation are dust collected by the Athena magnets and interior rock and soil surfaces exposed by the Athena Rock Abrasion Tool and by trenching with rover wheels

Emotions in context: examining pervasive affective sensing systems, applications, and analyses

Pervasive sensing has opened up new opportunities for measuring our feelings and understanding our behavior by monitoring our affective states while mobile. This review paper surveys pervasive affect sensing by examining and considering three major elements of affective pervasive systems, namely; “sensing”, “analysis”, and “application”. Sensing investigates the different sensing modalities that are used in existing real-time affective applications, Analysis explores different approaches to emotion recognition and visualization based on different types of collected data, and Application investigates different leading areas of affective applications. For each of the three aspects, the paper includes an extensive survey of the literature and finally outlines some of challenges and future research opportunities of affective sensing in the context of pervasive computing

Predictors of vitamin D status and its association with parathyroid hormone in young New Zealand children.

BACKGROUND: Despite increased awareness of the adverse health effects of low vitamin D status, few studies have evaluated 25-hydroxyvitamin D [25(OH)D] status in young children. OBJECTIVES: We aimed to assess vitamin D status on the basis of 25(OH)D and its relation with parathyroid hormone (PTH) and to identify possible predictors of 25(OH)D status in young children living in a country with minimal vitamin D fortification. DESIGN: Serum 25(OH)D and PTH concentrations were measured in a cross-sectional sample of children aged 12-22 mo [n = 193 for 25(OH)D, n = 144 for PTH] living in Dunedin, New Zealand (latitude: 45 degrees S). Anthropometric, dietary, and sociodemographic data were collected. RESULTS: The majority of children sampled in the summer (94%; 47 of 50) had 25(OH)D >50 nmol/L; however, nearly 80% of children sampled in the winter (43 of 55) had serum concentrations 60-65 nmol/L, a plateau in PTH was evident. CONCLUSIONS: Seasonal variation in 25(OH)D concentration implies that postsummer vitamin D stores were insufficient to maintain status >50 nmol/L year-round. Examination of the predictors of 25(OH)D in our model shows few modifiable risk factors, and thus effective dietary strategies may be required if future research determines that children with 25(OH)D concentrations <50 nmol/L are at significant health risk. This trial was registered at www.actr.org.au as ACTRN12605000487617

Validating DLL3-targeting CAR T in small cell lung cancer

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Sessions as Propositions

Recently, Wadler presented a continuation-passing translation from a session-typed functional language, GV, to a process calculus based on classical linear logic, CP. However, this translation is one-way: CP is more expressive than GV. We propose an extension of GV, called HGV, and give translations showing that it is as expressive as CP. The new translations shed light both on the original translation from GV to CP, and on the limitations in expressiveness of GV.Comment: In Proceedings PLACES 2014, arXiv:1406.331

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin