Time Series Heterogeneous Co-execution on CPU+GPU

Time series motif (similarities) and discords discovery is one of the most important and challenging problems nowadays for time series analytics. We use an algorithm called “scrimp” that excels in collecting the relevant information of time series by reducing the computational complexity of the searching. Starting from the sequential algorithm we develop parallel alternatives based on a variety of scheduling policies that target different computing devices in a system that integrates a CPU multicore and an embedded GPU. These policies are named Dynamic -using Intel TBB- and Static -using C++11 threads- when targeting the CPU, and they are compared to a heterogeneous adaptive approach named LogFit -using Intel TBB and OpenCL- when targeting the co-execution on the CPU and GPU.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Correction to: Prognostic influence of prior chronic obstructive pulmonary disease in patients admitted for their first episode of acute heart failure

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Anticholinergic Drug Burden and Delirium: A Systematic Review

Objectives: To investigate the association between anticholinergic drug burden (ADB), measured with anticholinergic drug scales, and delirium and delirium severity. Design: Systematic review. Setting and Participants: All available studies. Methods: A systematic literature search was performed in Medline, Embase, PsycINFO, Web of Science, CINAHL, Cochrane library, and Google Scholar. Studies evaluating the association between ADB (measured as a total score) and delirium or delirium severity, published in English, were eligible for inclusion. Results: Sixteen studies, including 148,756 persons, were included. Fifteen studies investigated delirium. ADB was measured with the Anticholinergic Risk Scale (ARS, n = 5), the Anticholinergic Cognitive Burden Scale (ACB, n = 6), the list of Chew (n = 1), the Anticholinergic Drug Scale (ADS, n = 5), a modified version of the ARS (n = 1), and a modified version of the ACB (n = 1). A high ADB, measured with the ARS, was associated with delirium (5/5). Also with the modified version of the ARS and ACB, an association was found between a high ADB and delirium during 3-month (1/1) and 1-year follow-up (1/1), respectively. When ADB was assessed with other scales, the results were inconclusive, with only 1 positive association for the ACB (1/6) and ADS (1/5) each. The possible association between ADB and delirium severity has also been investigated (ADS n = 2, Summers Drug Risk Number n = 1). One study found an association between a high ADB, measured with the ADS, and an increase in severity of delirium. Conclusions and Implications: ADB assessed with the ARS is consistently associated with delirium. The association found between the modified versions of the ARS and ACB and delirium needs confirmation. When ADB was assessed with other scales, the findings were inconclusive. The current findings suggest that the ARS might be a useful tool to identify patients at increased risk for delirium

Circuit de derivació de persones en règim penitenciari amb necessitats d’atenció intermèdia o de llarga durada

Atenció intermèdia; Atenció de llarga durada; Àmbit penitenciariIntermediate care; Long-term care; Penitentiary fieldAtención intermedia; Atención de larga duración; Ámbito penitenciarioL’objectiu d’aquest protocol és establir un sistema de coordinació eficaç entre els dispositius sanitaris dels centres penitenciaris i els dispositius sanitaris d’atenció intermèdia del SisCat, per donar resposta a les necessitats de salut de les persones dels centres penitenciaris un cop finalitzada la seva condemna o sortida derivada d’una necessitat de salut que limita la seva vida. Aquest document és fruit del consens de professionals experts del Departament de Justícia i el Departament de Salut i professionals assistencials del consell assessor del pla director directament implicats en l’atenció dels diferents àmbits assistencials del sistema penitenciari català

Yield, Quality and Phytochemicals of Organic and Conventional Raspberry Cultivated in Chihuahua, Mexico

Raspberry production represents an alternative for farmers in the temperate zones of Mexico. Due to the environmental impact caused by conventional agriculture, there is currently greater demand for organic food in the national and international market. To achieve this need, new fertilization techniques based on organic amendments are being tested. In the present study, yields and quality were evaluated over a 3-year period (2015, 2016 and 2017) as well as the phytochemical compounds of the production in 2017, with management of organic versus conventional fertilization of raspberry crop in open field in Cuauhtémoc, Chihuahua, Mexico. During the three years of study, the conventional fertilization system obtained higher yields, compared to the organic one, with values of 2,698 and 2,351 g per linear meter in 2015, 2,423 and 1,301 g per linear meter in 2016 and the data for 2017 were 3,077 and 2,550 g per linear meter, respectively. Regarding quality, the results showed no statistical differences between the two systems of production about colour, firmness, total soluble solids, titratable acidity and pH of the fruit. Differently the composition of phytochemicals, phenols, flavonoids, total anthocyanins and antioxidant capacity was better under the organic management. In conclusion, the conventional system showed higher yields, the quality of the fruits was not different between the two systems, while the levels of phytochemicals were higher with the organic farming. Therefore, it is important to continue the research in order to improve soil fertility and achieve higher yields under the organic management

Propuesta en supplyn chain management y logística en la empresa Just Time SAS.

El presente documento contiene una evaluación de la cadena de suministros y la logística que se aplica actualmente en la empresa Just time S.A.S, empresa del mercado nacional que actualmente se dedica al sector de transporte de productos de origen vegetal en las carreteras del Cesar, siendo actualmente INDUPALMA, su contratante. El mercado global ha sufrido una transformación en lo que va del siglo XXI, por lo que dentro de cada organización se hace necesario identificar que estrategias están siendo implementadas por la empresa, que tanto aportan estas a la competitividad de la misma para poder comparar con otras empresas del sector para buscar el mejoramiento continuo y así cumplir con las metas de desarrolla a corto, mediano y largo plazo. Una empresa será altamente competitiva en la medida que genere empleos, brinde un servicio de calidad, posea una cadena de suministros eficiente e implemente una logística que brinde competitividad ante los diferentes actores del sector en que se desempeña, por lo que aspectos como la evaluación de proveedores, las decisiones sobre productos, la integración de los aspectos del Supply Chain se hace cada vez más importante. Esto conlleva a que las organizaciones tengan que revisar aspectos como el transporte, el abastecimiento, distribución, control, verificación, producción, prestación del servicio hechos por la empresa Just Time S.A.S, es decir se aborda de manera detallada como esta gestiona su cadena de suministros. Finalmente podemos decir que el documento recopila la propuesta de trabajo hecho por el grupo para el aprovechamiento de la red de valor a la que pertenece la cadena de abastecimiento para la empresa de estudio, detallando su posición actual, la logística que implementa y haciendo sugerencias y cambios en los aspectos que consideramos sean falencias y que presenten oportunidades de mejora que se puedan implementar a corto y mediano plazo

Lightweight asynchronous scheduling in heterogeneous reconfigurable systems

The trend for heterogeneous embedded systems is the integration of accelerators and general-purpose CPU cores on the same die. In these integrated architectures, like the Zynq UltraScale+ board (CPU+FPGA) that we target in this work, hardware support for shared memory and low-overhead synchronization between the accelerator and the CPU cores make the case for exploring strategies that exploit a tight collaboration between the CPUs and the accelerator. In this paper we propose a novel lightweight scheduling strategy, FastFit, targeted to FPGA accelerators, and a new scheduler based on it, named MultiFastFit, which asynchronously tackles heterogeneous systems comprised of a variety of CPU cores and FPGA IPs. Our strategy significantly reduces the overhead to automatically compute the near-optimal chunksizes when compared to a previous state-of-the-art auto-tuned approach, which makes our approach more suitable for fine-grained applications. Additionally, our scheduler MultiFastFit has been designed to enable the efficient co-execution of work among compute devices in such a way that all the devices are busy while minimizing the load unbalance. Our approaches have been evaluated using four benchmarks carefully tuned for the low-power UltraScale+ platform. Our experiments demonstrate that the FastFit strategy always finds the near-optimal FPGA chunksize for any device configuration at a reasonable cost, even for fine-grained and irregular applications, and that heterogeneous CPU+FPGA co-executions that exploit all the compute devices are usually faster and more energy efficient than the CPU-only and FPGA-only executions. We have also compared MultiFastFit with other state-of-the-art scheduling strategies, finding that it outperforms other auto-tuned approach up to 2x and it achieves similar results to manually-tuned schedulers without requiring an offline search of the ideal CPU-FPGA partition or FPGA chunk granularity.This work was partially supported by the Spanish projects PID2019-105396RB-I00, UMA18-FEDERJA-108, and UK EPSRC projects ENEAC (EP/N002539/1), HOPWARE (EP/V040863/1) and RS MINET (INF\R2\192044). Funding for open access charge: Universidad de Málaga / CBUA

Plasma Molecular Signatures in Hypertensive Patients With Renin-Angiotensin System Suppression: New Predictors of Renal Damage and De Novo Albuminuria Indicators

Albuminuria is a risk factor strongly associated with cardiovascular disease, the first cause of death in the general population. It is well established that renin-angiotensin system suppressors prevent the development of new-onset albuminuria in naïf hypertensive patients and diminish its excretion, but we cannot forget the percentage of hypertensive patients who develop de novo albuminuria. Here, we applied multiple proteomic strategy with the purpose to elucidate specific molecular pathways involved in the pathogenesis and provide predictors and chronic organ damage indicators. Briefly, 1143 patients were followed up for a minimum period of 3 years. One hundred and twenty-nine hypertensive patients chronically renin-angiotensin system suppressed were recruited, classified in 3 different groups depending on their albuminuria levels (normoalbuminuria, de novo albuminuria, and sustained albuminuria), and investigated by multiple proteomic strategies. Our strategy allowed us to perform one of the deepest plasma proteomic analysis to date, which has shown 2 proteomic signatures: (1) with predictive value of de novo albuminuria and (2) sustained albuminuria indicator proteins. These proteins are involved in inflammation, immune as well as in the proteasome activation occurring in situations of endoplasmic reticulum stress. Furthermore, these results open the possibility of a future strategy based on anti-immune therapy to treat hypertension which could help to prevent the development of albuminuria and, hence, the progression of kidney damage.N

Kinescan/IBV V11: Biomechanical assessment in real time

[EN] Experts in biomechanical assessment are very interested in increasing precision of the measurements, reducing the needed time for evaluating patients and giving more flexibility to their labs. Therefore, we developed a new version of our system for kinematic analysis of human movement: Kinescan/IBV V11. Kinescan/IBV V11 is based in digital video technology and is able to make a distributed pre-processing. So it can analyse automatically movements in real time and use an unlimited number of cameras. The labs of functional assessment can reduce their costs, reduce their needed time for the assessment and increase their precision and reliability.[ES] El interés de los expertos en valoración biomecánica por incrementar la precisión de las medidas, reducir los tiempos de valoración y dotar de mayor flexibilidad a sus laboratorios es cada vez más creciente. Por esos motivos, hemos desarrollado una nueva versión de nuestro sistema de análisis cinemático de los movimientos humanos: Kinescan/IBV V11. Kinescan V11 es un sistema basado en tecnología vídeo digital con preprocesado distribuido que permite, entre otras características, analizar los movimientos en tiempo real y de forma automática y utilizar cuantas cámaras sean necesarias. Gracias a esta tecnología, los laboratorios de valoración funcional del IBV podrán reducir sus costes de operación, reducir los tiempos de valoración e incrementar su precisión y fiabilidad.Montero Vilela, J.; Parra Gonzalez, F.; Parrilla Bernabé, E.; Medina Ripoll, E.; Lopez Pascual, J.; Moreno Cano, R.; Castelli., A.... (2013). Kinescan/IBV v11: Valoración biomecánica en tiempo real. Revista de biomecánica. 59:35-38. http://hdl.handle.net/10251/38676S35385

Short physical performance battery is not associated with falls and injurious falls in older persons:longitudinal data of the SCOPE project

Introduction: Falls and fall-related injuries in older persons are a major public health problem. Our objective was to study the predictive value of the Short Physical Performance Battery (SPPB) in the cohort of the SCOPE project on falls, injurious falls, and possible difference of prediction between indoors and outdoors falls. Methods: For this sub-study of the SCOPE project participants reporting no falls at baseline, and survey data on falls at the 12-month and 24-month follow-up were included. Participant´s characteristics were assessed during the baseline interview and medical examinations. Falls as well as injurious falls and fall circumstances were obtained self-reported. SPPB and its association with fallers vs. no fallers at 12 and at 24 months were studied with logistic regression models. Results: The 1198 participants had a median age of 79 years (77–82), and a median SPPB of 10 (8–11), with a 52.5% of female. A total of 227 and 277 falls (12- and 24- month visits, respectively) were reported. In the crude model, the SPPB sum scores (p &lt; 0.001) as well as most single item scores were significant different between fallers and non-fallers over time. However, the association was attenuated in models adjusted for age, sex, marital status, number of medications, quality of life, handgrip strength, and muscle mass [e.g., 12 months; OR 0.94 (0.87–1.02)]. While SPPB fails to differentiate between injurious and non-injurious falls (p = 0.48), a lower SPPB score was associated with falls at home (p &lt; 0.01) after 24 months.Conclusion: SBPP was not able to significantly predict the risk of falling as well as experiencing an injurious fall. Trial registration: This study was registered prospectively on 25th February 2016 at clinicaltrials.gov (NCT02691546).</p