Análise de sentimentos na classificação de comentários online aplicando técnicas de text mining

Classificação ACM: H.2.8 Database Applications – Data Mining, H.4.2 Types of Systems – Decision SupportO crescimento dos sociais media proporcionou, nos últimos anos, um aumento significativo de comentários online que se refletem nas decisões de compra. Os comentários ajudam, por um lado, as empresas a recolher informações quanto à perceção dos consumidores em relação aos seus bens e serviços. Por outro lado, ajudam e influenciam os consumidores a centrarem a sua atenção nas recomendações que poderão estar mais alinhadas em satisfazer as suas necessidades, filtrando à partida uma grande quantidade de informação que poderá não responder a esses requisitos. O presente projeto tem como objetivo dar resposta a esta problemática através do estudo da plataforma Yelp. Para tal, foram extraídos 14.000 comentários, relacionados com diferentes produtos turísticos, com os respetivos votos (useful). Sobre estes foram aplicadas técnicas de text mining de modo a encontrar os principais sentimentos (positivos, neutros e negativos), tópicos e termos de cada comentário, que permitem explicar a sua utilidade. Durante a investigação, seguindo a metodologia CRISP-DM, organizou-se os comentários em tópicos, construiu-se o wordcloud com os termos mais utilizados pelos consumidores, procedeu-se à análise de sentimentos dos comentários, das entidades e dos tópicos correspondentes e, por último, construíram-se quatro modelos preditivos, calculando os erros de treino e teste. Os resultados obtidos mostram que o modelo Regressão Logística é o melhor dos modelos construídos, onde os termos: chair, valley, neighborhood e place food são os mais importantes para explicar a utilidade dos comentários. Agruparam-se ainda os comentários em 20 tópicos onde o tópico “Buffet” revelou ser o mais útil e com sentimento positivo.The growth of social media lead, in the past few years, to a significant increase of the online reviews that reflect buying decisions. These reviews, on one hand facilitate companies to acquire information regarding the perception of consumers, but on the other hand help and influence consumers to center their attention on the reviews that are better suited for their needs, thus filtering a huge amount of irrelevant information to meet their requirements. This project aims at addressing these issues and give some useful answers by using the Yelp platform. This study involves the extraction of 14.000 reviews, related to different tourism products, with the respective votes (useful). Text mining techniques were applied in order to identify and extract the main subjective sentiments (positives, negatives and neutral), topics and terms behind each review which then enabled us to understand the usefulness of the reviews. Throughout this study and by using the CRISP-DM methodology, the researcher organized the reviews by topics, has built a word cloud of the most used terms, performed the sentiment analysis on the reviews, the entities and related topics and finally built the predictive models, by measuring the train and test set. The results show that the logistic regression model is the best predictive model, where the terms: chair, valley, neighborhood and place food are the most important to explain the usefulness of comments. Still, it was possible to group the comments on 20 topics where the topic “Buffet” proved to be the most useful and positive sentiment

Perspectives for medicinal cannabis in Argentina: Advances in clinical trials in the world and Its use for chronical pain treatments

Cannabis is used around the world for medicinal, religious and recreational purposes. In 2018, the Argentine Republic approved new legislation, adapting to the provisions of the WORLD HEALTH ORGANIZATION. Law No. 27,350 regulates medical and scientific research on the medicinal, therapeutic and / or palliative use of the Cannabis plant and its derivatives. At the time of this publication, 5 projects were approved for the production of plant material and scientific studies. This work aims to show the results of the latest studies published in the world, on the effectiveness of treatment with medicinal cannabis or cannabinoids, in voluntary patients with chronic pain.Fil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentin

Leukotriene D4-induced Caco-2 cell proliferation is mediated by prostaglandin E2 synthesis

Leukotriene D4 (LTD4) is a pro-inflammatory mediator formed from arachidonic acid through the action of 5-lipoxygenase (5-LOX). Its biological effects are mediated by at least two G-coupled plasmatic cysteinyl LT receptors (CysLT1-2R). It has been reported an upregulation of the 5-LOX pathway in tumor tissue unlike in normal colon mucosa. Colon tumors generally have an increased expression of CysLT1R and colon cancer patients with high expression levels of CysLT1R have poor prognosis. We previously observed that the cyclooxygenase pathway is involved in the control of intestinal epithelial cancer cell growth through PGE2 production. The aim of this study was therefore to assess the effect of LTD4 binding with CysLT1R on Caco-2 cell growth. We note a number of key findings from this research. We observed that at a concentration similar to that found under inflammatory conditions, LTD4 was able to induce Caco-2 cell proliferation and DNA synthesis. Moreover, with the use of a specific receptor antagonist this study has demonstrated that the effect of LTD4 is a result of its interaction with CystLT1R. We also note the possible participation of the PLC-IP3-Ca2+/DAG-PKC signaling pathways in cytosolic PLA2 and [3H]AA release induced by LTD4-CystLT1R interaction. Finally, we found that the resulting activation of the AA cascade and the production of PGE2 eicosanoid could be related to the activation of cell signaling pathways such as ERK and CREB. These findings will help facilitate our understanding of how inflammatory mediators can affect the survival and dissemination of intestinal carcinoma cells

Bacterial nano cellulose as non-active pharmaceutical ingredient: Advances and perspectives

Nano Cellulose is commonly produced by the top-down enzymatic, mechanical and/or chemical treatments. In contrast, Bacterial Nano Cellulose (BNC) can be obtained by a bottom-up approach, where is biosynthesized from glucose using the direct action of specific bacterial strains. BNC impart attractive combinations of biologic and physicochemical characteristics such as biocompatibility, biodegradability, light weight, sustainability, and improved mechanical properties. The trend towards environmental sustainability and development of renewable resources has significantly increased interest. A critical aspect in BNC production is to identify a low-cost culture medium that can improve the yield of BNC and can be used as an economically viable solution for application in a range of fields. There is an immense perspective of BNC in health care as well as drug applications. Potential uses include barrier films, antimicrobial films, pharmaceuticals and drug delivery systems. Even though BNC has been demonstrated as nongenotoxic and noncytotoxic, further studies are required to completely address such issue. Key aspects for future development include the design of BNC for specific user requirements, the reduction of production costs, and the customization/functionalization using post production steps and different types of compounding/processing.Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Cerúsico, Nicolás Abel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentin

Bacterial nano cellullose as non-active pharmaceutical ingredient production optimization, quality control development and prototype design

Materials from bio-based resources have attracted immense research interest in recent years as a result of their very high potentials for fabricating several high-value products with low impact on the environment. Cellulose produced by some bacteria has received great attention. Bacterial Nano Cellulose (BNC) imparts attractive combinations of biophysicochemical characteristics and improved mechanical properties. The aims of this work was to develop growth media for increase BNC production, characterize a non-active pharmaceutical ingredient (NAPI), design an efficient quality control method by FTIR and SEM by compared that NAPI with commercial ones and present a first prototype of a pharmaceutical product. LB and KB media were modified and BNC obtained had better quality respect its crystallinity and/or polymerization degree than the BNC from commercial media. Different extraction processes were proposed, in no case microbiological material remnants has been found. Films for controlled drugs release prototype were made and its physical properties such as water solubility, moisture content, swelling property, UV barrier capacity were evaluated. BNC films present an additional advantage, having lower UV permeability than films with cellulose of vegetal origin, adding potentialities to a patch design that protects the tissue and the Active Pharmaceutical Ingredients.Fil: González, Exequiel Elías. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Cerúsico, Nicolás Abel. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Moreno, María Julieta. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; ArgentinaFil: Sesto Cabral, María Eugenia. Universidad Nacional de Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Biotecnología Farmacéutica y Alimentaria; Argentin

Extinção dos governos civis?da(des)necessidade e (des)legitimação dos mesmos

Dissertação de Mestrado MPA- Administração PúblicaConsiderando a recente decisão de “extinção” dos governos civis, a insuficiência de estudos sobre a mesma, e, atenta a emanação de uma agenda política na sociedade portuguesa, de há uns anos a esta parte, sobre a reforma administrativa do País, o presente trabalho pretende trazer à luz o enquadramento da designada “extinção” dos governos civis, com vista a compreender da relevância, sentido, necessidade e legitimação da existência e funcionamento dos Governos Civis, numa análise que se reparte numa tripla dimensão, a saber, histórico-cultural, administrativo-territorial, e jurídico-constitucional, e no quadro da decisão de “extinção” dos Governos Civis e do respetivo processo de encerramento, sem descurar a análise das competências e atribuições cometidas aos Governos Civis. No estudo empírico é feita uma abordagem metodológica quantitativa, com utilização do inquérito por questionário, definindo-se uma população alvo constituída pelo universo do Ministério da Administração Interna, e pelos ex-Governadores Civis, atuais Deputados e atuais presidentes de câmaras Municipais, com uma amostra final que inclui 97 respondentes. Após é feita a apresentação, análise e interpretação dos resultados, e discussão dos mesmos. Os resultados se evidenciam, por um lado, a desnecessidade e deslegitimidade dos Governos Civis no domínio administrativo-territorial, no sentido de que devem evoluir e dar lugar à reforma administrativa e à regionalização, tal já parece ambivalente no plano jurídico-constitucional, retomando-se a falta de legitimação politica e democrática da sua existência e funcionamento quando questionado, no essencial, sobre a sua manutenção e relevância. Conclusões do estudo que importa correlacionar e articular, para futuro, com a previsão constitucional do Representante do Governo, com a legislação comparada nos países da UE, em que os Governadores Civis, ou figuras próximas subsistem, e com os limites do municipalismo.Taking into consideration the latest decision to "extinguish" civil governments, insufficient studies on the subject, and the political agenda in the Portuguese society in the last few years concerning the administrative reform of the Country, this research work aims at bringing to light the framework of the so-called "extinction" of civil governments, so as to understand the relevance, meaning, necessity and legitimation of the existence and functioning of Civil Governments. In order to do that we carried out an analysis in three different dimensions - historical-cultural, administrative-territorial, and legal-constitutional - within the framework of the decision of the "extinction" of the Civil Governments and the respective closure process, without neglecting the study of the competencies and functions credited to Civil Governments. As far as the empirical analysis is concerned, a quantitative methodological approach was used, supported by a questionnaire survey. The target population was constituted by the universe of the Ministry of Internal Administration and by the former Civil Governors, current deputies and presidents of municipal councils, with a final sample that includes 97 respondents. Afterwards, follow the presentation, analysis and interpretation of the results and further discussion of the results. If, on the one hand, the results show the unnecessity and de-legitimizing of the Civil Governments in the administrative-territorial domain, in the sense that they must evolve and give rise to administrative reform and regionalization, on the other hand, that already seems ambivalent in a juridical-constitutional dimension due to lack of political and democratic legitimacy of its existence and functioning regarding its maintenance and relevance. In the future, it urges to correlate and articulate conclusions of the study with the constitutional prognosis of the Government Representative, the comparative legislation in the EU countries where the Civil Governors or equivalent entities still subsist, and the limits of municipalism.N/

Entrevista al Dr. Luis Federico Arias

Luis Arias fue destituido de su cargo como juez titular del juzgado contencioso administrativo nro. 1 de La Plata en un proceso plagado de irregularidades. El juri de enjuiciamiento que lo llevó adelante, compuesto por cinco conjueces legisladores y cinco conjueces abogados, se pronunció por su remoción en fallo dividido.Luis Arias fue destituido de su cargo como juez titular del juzgado contencioso administrativo nro. 1 de La Plata en un proceso plagado de irregularidades. El juri de enjuiciamiento que lo llevó adelante, compuesto por cinco conjueces legisladores y cinco conjueces abogados, se pronunció por su remoción en fallo dividido

Educação para a cidadania global (UNESCO):: um discurso reformista neoliberal

The article analyzes the content of education for global citizenship (UNESCO), questioningthe transformative perspectives announced and “pitfalls” contained in the text. It is madefrom a critical perspective, adding to the tradition of Marxism (especially Wood andMészáros), the peripheral and “decolonial” standpoint, highlighting the contributions ofPazello and Freire. It argues that, in the context of educational reformism, EGC is reducedto neoliberal discourse, an instrument of imperialism/coloniality, in the globalizationof capitalism. The article rejects this proposal and brings contributions to the reflectionon “emancipating” possibilities, through the decolonial critical and “tactical” use of thelanguage of education, human rights and democracy.El artículo analiza el contenido de la educación para la ciudadanía global (UNESCO),cuestionando las perspectivas transformadoras anunciadas y los “escollos” contenidosen el texto. Esto, desde una perspectiva crítica, sumando a la tradición del marxismo(especialmente Wood y Mészáros), la mirada “decolonial” y periférica, destacando losaportes de Pazello y Freire. Argumenta que, en el contexto del reformismo educativo, laECG se reduce al discurso neoliberal, instrumento del imperialismo/colonialidad, en laglobalización del capitalismo. Rechazando esta propuesta, el artículo trae aportes a lareflexión sobre las posibilidades “emancipadoras”, con el uso decolonial, crítico y “táctico”del lenguaje de la educación, los derechos humanos y la democracia.O artigo analisa o conteúdo da educação para a cidadania global (UNESCO), questionando perspectivas transformadoras anunciadas e “armadilhas” contidas no texto. Isso, a partir da perspectiva crítica, somando à tradição do marxismo (em especial, Wood e Mészáros), o olhar “descolonial” e periférico, destaque às contribuições de Pazello e Freire. Argumenta que, no quadro de reformismo educacional, a ECG reduz-se a discurso neoliberal, instrumento do imperialismo/colonialidade, na globalização do capitalismo. Recusando tal proposta, o artigo traz aportes à reflexão quanto a possibilidades “emancipadoras”, com o uso crítico-descolonial e “tático” da linguagem de educação, direitos humanos e democracia