360 research outputs found
Complementing Farmers' Genetic Knowledge Farmer Breeding Workshop in Turipaná, Colombia
This workshop explored the feasibility and methods for complementing farmer experts' knowledge and skills in the enhancement and conservation of agrobiodiversity
Plan de negocios para un colegio biling?e como una nueva unidad estrat?gica de negocios del Instituto Cultural Peruano Norteamericano - ICPNA
La tesis que se presenta a continuaci?n, es el plan de negocio para un colegio Biling?e como una nueva unidad estrat?gica de negocios del instituto cultural peruano norteamericano ? ICPNA. El objetivo es determinar la viabilidad comercial y econ?mica de la implementaci?n de un colegio biling?e en una de las sedes del ICPNA, aprovechando la capacidad ociosa del ICPNA y ante la creciente tasa de poblaci?n estudiantil en Lima. Se har? uso de uno de las edificaciones m?s modernas con las que cuenta el instituto, adem?s de la tecnolog?a y ?reas adecuadas para la correcta ense?anza de educaci?n inicial, primaria (hasta 3er grado). Bajo el posicionamiento que tiene el ICPNA, se realiz? una evaluaci?n a fin de conocer las necesidades de los padres de familia para la ense?anza a nivel escolar, de sus hijos. Destacando la gran iniciativa del ICPNA, pues no solo ayudar? a que se formen en las materias dentro de una estructura curricular adecuada y conforme a las normas del ministerio de educaci?n, sino que adem?s puedan contar con un soporte adecuado de un segundo idioma tan necesario en el presente y para el futuro profesional
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Age-Related Degradation of Nuclear Power Plant Structures and Components
This paper summarizes and highlights the results of the initial phase of a research project on the assessment of aged and degraded structures and components important to the safe operation of nuclear power plants (NPPs). A review of age-related degradation of structures and passive components at NPPs was performed. Instances of age-related degradation have been collected and reviewed. Data were collected from plant generated documents such as Licensing Event Reports, NRC generic communications, NUREGs and industry reports. Applicable cases of degradation occurrences were reviewed and then entered into a computerized database. The results obtained from the review of degradation occurrences are summarized and discussed. Various trending analyses were performed to identify which structures and components are most affected, whether degradation occurrences are worsening, and what was the most common aging mechanisms. The paper also discusses potential aging issues and degradation-susceptible structures and passive components which would have the greatest impact on plant risk
Linea base para la toma de decisiones en bioseguridad: desarrollo de un modelo para la evaluación de flujo de genes en yuca utilizando una linea androesteril (Manihot esculenta Crantz)
Raman spectroscopy of wurtzite and zinc-blende GaAs nanowires: polarization dependence, selection rules and strain effects
Polarization dependent Raman scattering experiments realized on single GaAs
nanowires with different percentages of zinc-blende and wurtzite structure are
presented. The selection rules for the special case of nanowires are found and
discussed. In the case of zinc-blende, the transversal optical mode E1(TO) at
267 cm-1 exhibits the highest intensity when the incident and analyzed
polarization are parallel to the nanowire axis. This is a consequence of the
nanowire geometry and dielectric mismatch with the environment, and in quite
good agreement with the Raman selection rules. We also find a consistent
splitting of 1 cm-1 of the E1(TO). The transversal optical mode related to the
wurtzite structure, E2H, is measured between 254 and 256 cm-1, depending on the
wurtzite content. The azymutal dependence of E2H indicates that the mode is
excited with the highest efficiency when the incident and analyzed polarization
are perpendicular to the nanowire axis, in agreement with the selection rules.
The presence of strain between wurtzite and zinc-blende is analyzed by the
relative shift of the E1(TO) and E2H modes. Finally, the influence of the
surface roughness in the intensity of the longitudinal optical mode on {110}
facets is presented.Comment: 28 pages, 12 figures. to be published in Phys. Rev.
Structural and optical properties of high quality zinc-blende/wurtzite GaAs hetero-nanowires
The structural and optical properties of 3 different kinds of GaAs nanowires
with 100% zinc-blende structure and with an average of 30% and 70% wurtzite are
presented. A variety of shorter and longer segments of zinc-blende or wurtzite
crystal phases are observed by transmission electron microscopy in the
nanowires. Sharp photoluminescence lines are observed with emission energies
tuned from 1.515 eV down to 1.43 eV when the percentage of wurtzite is
increased. The downward shift of the emission peaks can be understood by
carrier confinement at the interfaces, in quantum wells and in random short
period superlattices existent in these nanowires, assuming a staggered
band-offset between wurtzite and zinc-blende GaAs. The latter is confirmed also
by time resolved measurements. The extremely local nature of these optical
transitions is evidenced also by cathodoluminescence measurements. Raman
spectroscopy on single wires shows different strain conditions, depending on
the wurtzite content which affects also the band alignments. Finally, the
occurrence of the two crystallographic phases is discussed in thermodynamic
terms.Comment: 24 page
Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ
[Background] The CCAAT/enhancer-binding protein β (C/EBPβ) is a transcription factor implicated in the control of proliferation, differentiation, and inflammatory processes mainly in adipose tissue and liver; although more recent results have revealed an important role for this transcription factor in the brain. Previous studies from our laboratory indicated that CCAAT/enhancer-binding protein β is implicated in inflammatory process and brain injury, since mice lacking this gene were less susceptible to kainic acid-induced injury. More recently, we have shown that the complement component 3 gene (C3) is a downstream target of CCAAT/enhancer-binding protein β and it could be a mediator of the proinflammatory effects of this transcription factor in neural cells.[Methods] Adult male Wistar rats (8–12 weeks old) were used throughout the study. C/EBPβ+/+ and C/EBPβ–/– mice were generated from heterozygous breeding pairs. Animals were injected or not with kainic acid, brains removed, and brain slices containing the hippocampus analyzed for the expression of both CCAAT/enhancer-binding protein β and C3.[Results] In the present work, we have further extended these studies and show that CCAAT/enhancer-binding protein β and C3 co-express in the CA1 and CA3 regions of the hippocampus after an excitotoxic injury. Studies using CCAAT/enhancer-binding protein β knockout mice demonstrate a marked reduction in C3 expression after kainic acid injection in these animals, suggesting that indeed this protein is regulated by C/EBPβ in the hippocampus in vivo.[Conclusions] Altogether these results suggest that CCAAT/enhancer-binding protein β could regulate brain disorders, in which excitotoxic and inflammatory processes are involved, at least in part through the direct regulation of C3.This work was supported by MINECO, Grant SAF2014-52940-R and partially financed with FEDER funds. CIBERNED is funded by the Instituto de Salud Carlos III. JAM-G was supported by CIBERNED. We acknowledge support of the publication fee by the CSIC Open Access Publication Support Initiative through its Unit of Information Resources for Research (URICI).Peer reviewe
Moderate alcohol consumption increases insulin sensitivity and ADIPOQ expression in postmenopausal women: a randomised, crossover trial
Aims/hypothesis To determine whether 6 weeks of daily, moderate alcohol consumption increases expression of the gene encoding adiponectin (ADIPOQ) and plasma levels of the protein, and improves insulin sensitivity in postmenopausal women. Methods In a randomised, open-label, crossover trial conducted in the Netherlands, 36 apparently healthy postmenopausal women who were habitual alcohol consumers, received 250 ml white wine (~25 g alcohol/day) or 250 ml of white grape juice (control) daily during dinner for 6 weeks. Randomisation to treatment allocation occurred according to BMI. Insulin sensitivity and ADIPOQ mRNA and plasma adiponectin levels were measured at the end of both periods. Insulin sensitivity was estimated using the homeostasis model assessment of insulin resistance (HOMA-IR). Levels of ADIPOQ mRNA in subcutaneous adipose tissue were determined by RT-PCR. Results All subjects completed the study. Six weeks of white wine consumption reduced fasting insulin (mean¿±¿SEM 40.0¿±¿3.4 vs 46.5¿±¿3.4 pmol/l; p
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