10 research outputs found
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
- Author
- Abbas Jalal
- Abraham Sybil
- Ackert Jessica
- Adams Patricia
- Aggarwala Gaurav
- Aher Nutan
- Ahlqvist Jørn
- Ahn Chul Woo
- Akers Teresa
- Akhras Ronald
- Akhter Faiq
- Aksentyev Sergey
- Al Kawas Firas
- Alexander Karen
- Althouse Denise
- Altobelli Desma
- Alvarisqueta Andres
- Ambrosy Andrew
- Andersen James
- Andersen Ulla
- Anderson Michelle
- Anglade Moise
- Arbañil Hugo
- Arciszewska Malgorzata
- Argoud Georges
- Ariani Mehrdad
- Ashdji Reswan
- Avogaro Angelo
- Avramidis Iakovos
- Axthelm Christoph
- Aye Myint
- Babi Charleen
- Bachus Erasmus
- Baik Sei-Hyun
- Bailey Matt
- Bakhtari Ladan
- Baksi Arun
- Balasubramani Mathangi
- Baldovino Jorge
- Banach Marek
- Banerjee Subhash
- Bartlett Andrew
- Bartone Susan
- Baum Howard
- Bays Harold
- Bazhan Larysa
- Beasley Richard
- Beaudry Yves
- Beaulieu Gail
- Beboso Ronnie
- Bedard Jacques
- Beijerbacht Hugo Peter
- Belfort de Aguiar Renata
- Benjamin Sabrina
- Berger Dirk
- Berlingieri Joseph
- Berndtsson Blom Katarina
- Besada Diego
- Bethel M Angelyn
- Bhagwat Ravi
- Bhargava Anuj
- Bhosale Archana
- Bieler Tasso
- Bijata-Bronisz Renata
- Birkeland Kare
- Birkenfeld Andreas
- Blagden Mark
- Bloomfield Gerald
- Bode Bruce
- Boemi Massimo
- Bonadonna Riccardo
- Bondar Irina
- Bott Jochen
- Bousboulas Stavros
- Boye Alain
- Bratcher Christina
- Breneman Jody
- Briskin Toby
- Bristianou Magdalini
- Brockmyre Andrew
- Broughton Raymond
- Brown Judith
- Brown Kim
- Brychta Tomas
- Brønnum-Schou Jens
- Budhraja Madhusudan
- Bull Georgina
- Bundy Charles
- Burgess Lesley
- Busch Klaus
- Caca Karel
- Cadinot Didier
- Calderon Jorge
- Calella Pedro
- Califf Robert M
- Calvo Gómez Carlos
- Camacho Luis
- Cannon Kevin
- Cano Rodríguez Isidoro
- Cantero Maria Cecilia
- Carr Jewell
- Casson Ed
- Castaño Patricia
- Castro Conde Almudena
- Cathcart Harold
- Cavale Arvind
- Cech Vladimir
- Cequier Fillat Angel
- Cervantes-Escárcega Jose-Luis
- Cha Bong-Soo
- Chau Tuan
- Chaykin Louis
- Chehayeb Raja
- Chen David
- Chen Jung-Fu
- Chertkoff Alejandro
- Cheung Deanna
- Cheung Stephen
- Chevts Julia
- Chiang Chern-En
- Childress Richard
- Christian Tamra
- Chung Choon-Hee
- Coetzee Kathleen
- Cohen Allan
- Coker Rebecca
- Cole Joanna
- Collier Jeannie
- Condit Jonathan
- Consoli Agostino
- Conway James
- Cooksey Erin
- Cookson Tobias
- Cooper John
- Cooper Lauren
- Copland Allan
- Cornel Jan
- Cornett George Mitchell
- Crenier Laurent
- Cuadrado Jesus
- Cuatrecasas Cambra Guillem
- Cusson Jean
- D'Agostino Ralph B
- D'Agostino Ralph B.
- Daga Shruti
- Damyanova Velichka
- Dauber Ira
- Davila William
- Dawood Saleem
- De Armas Luis
- De Cosmo Salvatore
- De Loredo Luis
- De Teresa Parreño Luis
- de Álvaro Moreno Fernando
- Dean Julius
- Debroye Corinne
- Del Prato Stefano
- Del Prato Stefano
- Delgado Lista Javier
- Della Siega Anthony
- DeMets David
- Demidova Irina
- Derezinski Tadeusz
- Deshpande Sameer
- Detweiler Robert
- Devore Adam
- Di Bartolo Paolo
- Di Giovanna Michael
- Diaz Ernesto
- Dimitriadis Georgios
- Dimitrov Stefan
- Distiller Larry
- Dombrowski Keith
- Dominguez Andrea
- Domínguez Escribano José Ramón
- Donaldson Jill
- Donaubauer Torsten
- Dor Isaac
- Dotta Francesco
- Dreval Alexander
- Drummond Waymon
- Dumas Richard
- Dumbre Snehal
- Dungan Kathleen
- Durán García Santiago
- Duyck Francis
- Dvorakova Eva
- Dzongowski Peter
- Eagerton Donald
- Eapen Zubin
- Earl John
- Eaton Charles
- Ebo Geraldine
- Edelsberger Tomas
- Eliasson Bjorn
- Eliasson Ken
- Elisaf Moses
- Ellison Howard
- Elvira González Javier
- Emslie-Smith Alistair
- Endsley Patricia
- Enns Robert
- Erlinger Rudolf
- Ershova Olga
- Español Maria Vanesa
- Espinoza Augusto Dextre
- Farris Neil
- Ferguson Murdo
- Fernandez-Salazar Eva
- Fernández Rodríguez José María
- Fiel Thomas
- Finkelstein Hernan
- Firek Anthony
- First Brian
- Fleming John
- Flota-Cervera Luis Fernando
- Forgosh Les
- Frechtel Gustavo
- French William
- Fretes Jose
- Friedman Daniel
- Frontoni Simona
- Funke Klaus
- Fushtey Ivan
- Gadzinski Waldemar
- Gajek Jacek
- Galatius Søren
- Galetta Marianna
- Galstyan Gagik
- Gambineri Alessandra
- Gandy Winston
- Garcia Ronald
- Garganeeva Alla
- Garrido Santos Natalia
- Garrido Elizabeth
- Garvey Louisa
- Gaudet Daniel
- Gazzaruso Carmine
- Gentry Tracy
- Giaccari Andrea
- Gill Santosh
- Giorgino Francesco
- Goday Arno Alberto
- Godse Rupali
- Gomez Huelgas Ricardo
- Gonzales Rolando Vargas
- Gonzalez Joaquin
- González Juanatey José Ramón
- González-González José Gerardo
- Goodman Shaun
- Gordon Murray
- Gouet Didier
- Grachova Mariya
- Granger Christopher B
- Granger Christopher B.
- Green Fiona
- Green Jennifer B
- Green Jennifer B
- Greene Deb
- Greene Stephen
- Grondin Francois
- Grosskopf Josef
- Groutars Reginald G.E.J.
- Guerci Bruno
- Guice Michael
- Guimaraes Patricia
- Gulseth Hanne
- Gummadi Siva
- Gunstone Anthony
- Gupta Anil
- Gupta Milan
- Gupta Nikita
- Guttormsen Gaute
- Ha JuYoung
- Hackenyos Jonathan
- Haddock Trevorlyn
- Hagenow Andreas
- Hairston Kristen
- Hajdú Csaba
- Halciakova Katarina
- Halperin Frank
- Haluzik Martin
- Hamann Monika
- Hanson Lenita
- Haque Ghazala
- Harcsa Eleonóra
- Harris Tara
- Harrison Lindsay
- Harrison Rob
- Hartard Manfred
- Hartman Israel
- Heitner John
- Hejeebu Srini
- Henry Patrick
- Hereghty Belinda
- Hermany Paul
- Hernandez Mijares Antonio
- Hernandez Adrian F
- Hernandez Adrian F.
- Hernandez-Cassis Carlos
- Heymer Peter
- Hidalgo Horacio
- Higgins Alexander
- Hoek Boudewijn A
- Holman Rury
- Hoogslag Pieter A.M.
- Houle Pierre-Alain
- Hove Jens
- Howell Christina
- Hramiak Irene
- Huppertz Wolfgang
- Hutayanon Pisit
- Ibrahim Hassan
- Illies Gabriele
- Issa Basil
- Izmozherova Nadezhda
- Jackson-Voyzey Ewart
- Jacob Stephan
- Jacobs Shahram
- James Kourtnei
- James Rachel
- Jang Hak Chul
- Janmohamed Salim
- Janmohamed Salim
- Jarosz Marie
- Jenkins Wendy
- Jensen Jan Skov
- Jerjes-Díaz Carlos Sánchez
- Jiménez Díaz Víctor Alfonso
- Jintapakorn Woravut
- Jodar Gimeno Esteban
- Johnson Andrew
- Johnson David
- Johnson Megan
- Jones Michael
- Jones Nigel P
- Jones Nigel P
- Jordan Dedrick
- Joshi Parag
- Jung Thomas
- Kadgaonkar Neha
- Kahrmann Gerd
- Karetnikova Victoria
- Karka Mounika
- Karmalkar Anisha
- Kast Petra
- Kaster Steven
- Katerenchuk Vitaliy
- Kellerer Monika
- Kellum Daniel
- Kelly Aoife
- Kempe Hans-Peter
- Kessler Laurence
- Khandelwal Chaitali
- Kharakhulakh Marina
- Khariouzov Andrei
- Khokhlov Aleksandr
- Kim Chong-Jin
- Kim Christopher
- Kim Ellen
- Kim Hye Soon
- Kim In Joo
- Kirby William
- Klausmann Gerhard
- Klein Christiane
- Kleinecke-Pohl Uwe
- Kleinertz Klaus
- Klodawska Katarzyna
- Knouse Albert
- Kobalava Zhanna
- Kober Lars
- Koch Thorsten
- Kocsis Gyozo
- Kolls Brad
- Kong David
- Konyves Laszlo
- Kooy Adriaan
- Korpachev Vadym
- Kosch Christine
- Koshelskaya Olga
- Kosiborod Mikhail
- Koskinen Pekka
- Kosmacheva Elena
- Kostin Vladimir
- Kotsa Kalliopi
- Kouz Simon
- Kovacheva Snezhina
- Kovacs Christopher
- Koziolova Natalia
- Kragten Johannes A.
- Kravchun Nonna
- Kristiansen Ole Peter
- Krizova Jarmila
- Krzyzagorska Ewa
- Kulback Steven
- Kulkarni Mangesh
- Kumar Mariananda
- Kumar Rakesh
- Kumar Somesh
- Kumari Aditi
- Kuruvanka Tulsidas
- Kuzin Anatoly
- Labroo Ajay
- Lalau Jean-Daniel
- Landry Daniel
- Larin Oleksandr
- Larnefeldt Hans
- Lasswell William
- Lastuvka Jiri
- Lauder Steven
- Lauro Davide
- Lee Eun Young
- Lee Hyoung Woo
- Lee Kwan-Woo
- Lee Moon Kyu
- Leiter Lawrence A
- Leiter Lawrence A.
- Lentz John
- Lenzmeier Thomas
- Lesnov Victor
- Lewis David
- Li Wenyan
- Li Zhaoping
- Lieverse Aloysius G.
- Lif-Tiberg Cornelia
- Lillestol Michael
- Linderfalk Carina
- Lindsay Alistair
- Little Raymond
- Litvak Marcos
- Llamas Edmundo-Alfredo Bayram
- Lokhngina Yuliya
- Lombard Landman
- Longley Troy
- Lonn Eva
- Lopes Renato
- Lopez-Sendon Jose
- Lorimer Jamie
- Lorra Babette
- Lorraine Richard
- Loureyro Juan
- Lozanov Lachezar
- Lucas Morante Tomás
- Luedemann Joerg
- Luna Alejandro
- Lund Gustav
- Lund Per
- Lundman Pia
- Luttermann Matthias
- Lysenko Tatyana
- Maclean Malcolm
- Madej Andrzej
- Maffei Laura
- Makotoko Ellen
- Maldonado Natacha
- Mandal Trisha
- Mandawat Aditya
- Mankovsky Boris
- Manrique Helard
- Marazuela Monica
- Margaritov Viktor
- Markov Valentin
- Marquess Marsha
- Martell Claros Nieves
- Mathews Robin
- Mathieu Chantal
- Mauricio Puente Didac
- Maxeiner Stephan
- Mayorov Alexander
- McGuire Darren
- McKeown-Biagas Cecilia
- McKnight John
- McLaughlin Patricia
- McMurray John J.V.
- McMurray John J.V.
- McNeill Robert
- Mehta Anand
- Mehta Rajendra
- Melchior Thomas
- Melidonis Andreas
- Melloni Chiara
- Mena Ribas Elena
- Merino Torres Juan Francisco
- Mezquita Raya Pedro
- Mhambrey Ankita
- Miekus Pawel
- Migdalis Ilias
- Mihaylova-Shumkova Rositsa
- Milek Karsten
- Miller Alan
- Miller Diane
- Mitrakou Asimina
- Moelle Andrea
- Mohr Gasparini Diego
- Moiseev Sergey
- Moodley Rajendran
- Moon Keon-Woong
- Morales-Palomares Ellen
- Moran Joseph
- Morawski Emily
- Moris Linda
- Mucsi János
- Murphy Karen
- Muzulu Solomon
- Muñoz Ernesto German Cardona
- Myasoedova Svetlana
- Mykhalchyshyn Galyna
- Myshanych Halyna
- Nadar Madhumitha
- Nadar Venkatesh
- Naicker Pallavi
- Namgung June
- Nauck Michael
- Neumann Gerhard
- Nikolaeva Antoaneta
- Nischik Ruth
- Noronha Drusilla
- Nubiola Calonge Andreu
- Nyvad Ole
- O'Connell Ian
- O'Connor Thomas
- O'Mahony William
- Odio Alberto
- Oehrig-Pohl Edith
- Oleksyk Olga
- Olesinska-Mader Martyna
- Olsson Åke
- Oosthuysen Wessels
- Opiela Jaroslaw
- Ordoñez Sánchez Xavier
- Orio Silvia
- Orlenko Valeriia
- Orsi Emanuela
- Overton Robert
- Oyesile Babatunde
- Ozaki Risa
- Pagkalos Emmanouil
- Paolisso Giuseppe
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- Parker Reginald
- Pascoe-Gonzalez Sara
- Pascual Izuel Jose Maria
- Pashkovska Nataliia
- Patel Chetan
- Patel Prashant
- Patel Rajesh
- Patel Rajivkumar
- Patel Vickas
- Patil Ashwini P
- Patil Suradnya
- Patterson Catherine
- Pauker Zsolt
- Pearson Ewan
- Pelayo-Orozco Emilia Susana
- Perea Castilla Verónica
- Perez Manghi Federico
- Perez Soto Isabel
- Perez Kathleen
- Perriello Gabriele
- Pertseva Nataliia
- Pesarchick Jean
- Peterson Sean
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- Petró Gizella
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- Philip Sam
- Phillips Lawrence
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- Pinto Miguel
- Piperek Martin
- Plassmann Georg
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- Potnis Omkar
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- Price-Olsen Emma
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- Pérez Pérez Antonio
- Quesada Charneco Miguel
- Quesada Simón Angustias
- Raad George
- Raclavska Lea
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- Raikhel Marina
- Raisinghani Ajit
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- Ramirez-Diaz Santiago-Paulino
- Raorane Amruta
- Rasouli Neda
- Rauzi Frank
- Rebrov Andrey
- Redón Mas Josep
- Regner Stefan
- Rego Iraeta Antonia
- Reich Dennis
- Rethaford Renee
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- Revoredo Frederick Massucco
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- Rieker Werner
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- Rodriguez Papini Nelson
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- Romanczuk Piotr
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- Rosenberg Anne E
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- Sanmartin Berglund Johan
- Sansanayudh Nakarin
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- Siegel Anna
- Sigal Helena
- Sigmon Kristina
- Sigmon Kristina N
- Silhova Elena
- Sinay Isaac
- Singh Narendra
- Sivalingam Kanagaratnam
- Sjöberg Folke
- Skokowska Ewa
- Smirnov Ivan
- Smith Paul
- Smith Peter
- Soffer Joseph
- Sokolova Nadezhda
- Solanki Sheetal
- Somerville Matthew
- Somerville Matthew C
- Soto González Alfonso
- Sowell Margaret
- Sposetti Georgina
- Srimahachota Suphot
- St-Maurice Francois
- Stankiewicz Andrzej
- Stasinska Teresa
- Stead Janet
- Steindorf Joerg
- Stewart Murray
- Stockhausen Juergen
- Stone Allegra
- Stonesifer Larry
- Storey Daniel
- Stoyanova Zhasmina
- Stuebler Petra
- Suh David
- Sukumaran Usha
- Swart Hendrik P.
- Sándor Vangel
- Söderberg Stefan
- Taeschner Heidrun
- Taft Lin
- Tahir Mohammed
- Tan Anjanette
- Tan Choon Beng Kathryn
- Tan Marilyn
- Taylon Alain
- Tentolouris Nikolaos
- Tews Dietrich
- Thakkar Maitreya
- Thomas Betsy
- Thorpe Karl
- Thorpe Karl M
- Thuan Jean-Francois
- Tien Kai Jen
- Tinahones Madueno Francisco
- Tirador Louie
- Tonolo Giancarlo
- Torres-Colores Jose Juan
- Torstensson Ingemar
- Trescoli Serrano Carlos
- Trevisan Roberto
- Tricoci Pierluigi
- Tripathy Devjit
- Trznadel-Morawska Iwona
- Tsapas Apostolos
- Tschoepe Diethelm
- Tseng Shih-Ting
- Tu Shih-Te
- Tugwell Barna
- Tzatzagou Glykeria
- Ulied Armiñana Angels
- Ulla Maria
- Urbanek Robin
- Uwaifo Gabriel
- Van Gaal Luc
- Vandyne Beth
- Vaphare Ashok
- Vasilevskaya Olga
- Vass Viktor
- Vedere Amarnath
- Vemulapalli Sreekanth
- Venugopal Chandra
- Verbovaya Nelli
- Vercammen Chris
- Verra Fernando
- Vidrio-Velázquez Maricela
- Viergever Eric P.
- Villagordoa-Mesa Juan
- Vishneva Elena
- Vizel Saul
- Vlasenko Maryna
- Vo Anthony
- Voinot Christel
- Vorobyev Sergey
- Vorokhobina Natalya
- Vouillarmet Julien
- Vrkoc Jan
- Wang Chih-Yuan
- Wang Ji-Hung
- Watson Anthony
- Watson David
- Welch Michelle
- Welker James
- White Alexander
- Wilhelm Karl
- Willis John
- Wilson Matt
- Wilson Tim
- Witek Robert
- Wium Cecilie
- Womer Terese
- Woo Vincent
- Wraight Ella
- Wynne Alan
- Xing Weibing
- Yamwong Sukit
- Yazdani Shahram
- Ye June
- Yoo Soon Jib
- Yordanov Victor
- Yu Jaemyung
- Zabalua Silvina
- Zaidman Cesar
- Zang Eddie
- Zanozina Olga
- Zeller-Stefan Helga
- Zhdanova Elena
- Zlova Tetiana
- Zubiate Carlos
- Zykova Tatyana
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
Capitulo 2. Ciencias Naturales y Ciencias Básicas, Ingeniería y Tecnología
- Author
- Aguirre Cabrera Carmen Adriana
- Alava Viteri Clemencia
- Andrade Trujillo Gilma Paola
- Arrubla Hoyos Wilson de Jesús
- Barrera Siabato Andrea Isabel
- Barrios Montes Erik Miguel
- Benítez Rodríguez Edson Daniel
- Bojacá Garavito Edgar Alonso
- Bueno Rincón Gherson Emmanuel
- Campaña Bastidas Sixto Enrique
- Caro Martínez Camilo Andrés
- Carvajal Ruiz German
- Castellanos Blanco Nahury Yamile
- Castrillón Ortega Juan Camilo
- Castro Triana Augusto
- Castro Vergara Ana Milena
- Cuevas Castañeda Cristian Camilo
- Diaz Martínez Fernando José
- Díaz Raga Hugo Hernando
- Díaz Torres María Jenny
- Escobar-Diaz Manuel J.
- Fernando Camelo Elber
- Ferrer Camila Andrea
- Florido Alex Enrique
- Flórez Martínez Alexander
- Getial Pantoja John Jairo
- González Acosta Andrea Yaneth
- González Clavijo Claudio Camilo
- Guzmán Méndez William Alberto
- Gómez Argote Mireya
- Hernández Murillo Luz Karime
- Herrán José Miguel
- Hilarión Novoa Francisco Javier
- Ibáñez Bersinger Cristian Camilo
- Lagos Mendoza Sofia Loreney
- López Ortiz Iván Arturo
- Marín Idárraga Diego Alberto
- Marín Peña Jairo Yamid
- Mercado Palencia Yolima Esther
- Millán Cifuentes Andrés Felipe
- Molina Arévalo Natalia
- Montes Arroyo Abel José
- Mora July Natalia
- Morales Kelly Vanesa
- Mosquera Anglo Hermes
- Noguera Torres Adriana del Pilar
- Ordoñez Daizzy Janeth
- Ortiz Palma Luis Alberto
- Peña Hidalgo Hernando José
- Polanco Contreras Ramiro Hernán
- Puerto González Luz Angela
- Pérez Burbano Jhon Jairo
- Pérez Holguín Rafael
- Pérez Monroy Egniyiredt
- Pérez Waltero Harold Esneider
- Pérez Leonardo Andrés
- Quimbayo Murillo Sharik Vanessa
- Quintana Fuentes Lucas Fernando
- Reyes Carvajal Ángelo Albano
- Rodríguez Bolaño Moisés de Jesús
- Rodríguez Niño María Consuelo
- Rodríguez Pérez Johny Roberto
- Rojas Aldana Yeison Smith
- Romero Torres Mariano Esteban
- Rubiano Llorente Jaime
- Rubio Vanegas Carmen Emilia
- Rubio Vanegas Gloria Alejandra
- Rueda Carreño Adrián
- Rúa Pérez Santiago
- Sendoya Diego Fernando
- Sierra Benítez Angélica María
- Tapias Juan Esteban
- Torres Vargas Golda Meyer
- Vargas Flórez Jesús Omar
- Vargas Rojas Dennis
- Velandia Tacuma José Fernando
- Vera Romero Carlos Alberto
- Villamizar Núñez Cesar Antonio
- Villegas Yiosef Alonso
- Ávila García Bibiana del Carmen
- Publication venue
- 'Gunadarma University'
- Publication date
- 28/06/2021
- Field of study
La diseminación de la Levitación Magnética, a pesar de lo antiguo de su tecnología, ha sido limitada. Debido a sus inconvenientes prácticos de implementación, su uso es bastante restringido, comparado con otras tecnologías (SCMaglev japonés, Transrapid alemán, o productos comerciales para ocio y entretenimiento). Con el boom de las tecnologías limpias y amigables con el medio ambiente y en concordancia con los objetivos del milenio, es pertinente plantearse el objetivo de optimizar el proceso de Levitación Magnética para generar un aprovechamiento de las ventajas de esta tecnología a nivel mecánico, eléctrico, y ambiental.
Actualmente la UNAD adelanta un proyecto de investigación cuyo objetivo es generar un modelo físico matemático de levitación magnética para aplicaciones en ingeniería. De este proyecto se ha derivado una primera revisión sistemática de los principios físicos y los modelos vigentes en Levitación Magnética
La literatura infantil: Una experiencia que favorece los procesos relacionados con el lenguaje
- Publication venue
- Medellin
- Publication date
- Field of study
Ubicación en Biblioteca USB Medellín (Campus): CD-2509tEsta investigación corresponde al Trabajo de Grado, que surge a partir de la necesidad de que la literatura sea vista en el ámbito educativo no solo como la lectura de cuentos; sino también, como un amplio mundo de posibilidades que ofrece a través de sus diferentes lenguajes expresivos (cuento, pintura, teatro, canción, trova etc.) Un mecanismo interactivo de enseñanza, que promueve que el niño o niña pueda encontrase consigo mismo, a la vez que le permite potencializar sus habilidades realizando verdaderos aprendizajes, acerca del mundo social y físico que lo rodea. Por lo cual se tuvo como propósito promover la literatura infantil como favorecedora del desarrollo de los procesos orales y escritos de los niños y niñas de preescolar; basado en una metodología cualitativa con un enfoque etnográfico, que, facilita una observación tanto activa como participativa, y permite un acercamiento e intervención de forma más directa. Para el desarrollo de dicha investigación, se implementó una serie de estrategias de acción (encuestas, grupos focales, lecturas de cuentos, dibujos, títeres, teatro, carrusel literario etc.) que permitieron recolectar y analizar información; así como búsqueda y análisis de referencias teóricas. Finalmente esta investigación, asume la literatura como un mundo de posibilidades, alternativas abiertas que deviene de realidades que solo pueden adentrarse en tanto logran explorarse y vivirse. Pues, es un medio movilizador y experiencial, una puerta que se abre presentando una serie de campos que promulgan situaciones que favorecen los procesos del lenguaje (lectura y escritura). Por ello la literatura sin duda alguna es un medio por el cual se permite al niño explorar, imaginar, crear, construir y no hay nada más significativo que ver como se involucran en diferentes situaciones de la vida diaria, que hacen posible la formación continúa; razón por la cual es indispensable vivir la literatura desde la infancia, reconociendo tanto sus virtudes formativas como recreativas y distractoras
Safety and tolerability of subcutaneous trastuzumab for the adjuvant treatment of human epidermal growth factor receptor 2-positive early breast cancer: SafeHer phase III study's primary analysis of 2573 patients
- Author
- Abulkhair Omalkhair
- Adams Jocelyn
- Afonso Noemia
- Agrawal Rajiv
- Ahmed Samreen
- Ahn Jin-Seok
- Aieta Michele
- Akbulut Hakan
- Aktas Bahriye
- Al-Sakaff N.
- Alcedo Juan Carlos
- Alcibar Arrate Plazaola
- Aleman Diana
- Alexandre Jerome
- Alhasso Abdulla
- Allegrini Giacomo
- Allerton Rozenn
- Alonso Isabel
- Altundag Kadri
- Alvarez Pilar Lopez
- Amadori Dino
- Anwar Suhail
- Aramburo Antonio Fernandez
- Aravantinos Gerasimos
- Arbona Esther
- Archer Caroline
- Ardavanis Alexandros
- Arias Carmen Cañabate
- Arican Ali
- Artagaveytia Nora
- Artignan Xavier
- Asensio Teresa Ramon Y. Cajal
- Ashford Richard
- Asselah Jamil
- Assi Hazem
- Ataseven B.
- Atmakusuma Djumhana
- Augustin Doris
- Azeem Hamdy Abdel
- Azim H. A.
- Aziz Amr Abdel
- Aziz Zeba
- Bach Isabelle Sillet
- Badulescu Florinel
- Bakker Sandra
- Balser Christina
- Bandidwattanawong Chanyoot
- Barletta Hugues
- Barraclough Lisa
- Bastick Patricia
- Bauer Lelia-Eveline
- Beato Carlos Augusto
- Bechtner Christina
- Beguier Emmanuel
- Beith Jane
- Berdah Jean-François
- Bertelli Gianfilippo
- Beyer Greta
- Bidoli Paolo
- Bishop Jill
- Biti Giampaolo
- Bittner Nora
- Blaisse R. J. B.
- Boer Katalin
- Bollet Marc
- Bordonaro Roberto
- Bottini Alberto
- Bourgeois Hugues
- Bouzid Kamel
- Bozcuk Hakan
- Branson Tony
- Braun J. J.
- Bressac Claude
- Brezden-Masley Christine
- Brucker Cosima
- Burki Franck
- Busch Steffi
- Butt Mohammed
- Bystricky Branislav
- Bückner Ute
- Campone Mario
- Cardoso Fátima
- Caremoli Elena Rota
- Carrion Ramon Perez
- Carterni Giacomo
- Casalnuovo Monica
- Cascallar Diana
- Castro Hugo
- Cavanna Luigi
- Cazzaniga Marina
- Ceric Timur
- Cesas Alvydas
- Chacon Jose
- Chakrabarti Amit
- Chakraborti Prabir
- Chang Tsai-Wang
- Cheah Nellie Lay Chin
- Chia Stephen
- Ching Lee Wei
- Chong Flora Li Tze
- Christensen Bernd
- Churn Mark
- Ciule Larisa
- Coate Linda
- Coeffic David
- Cognetti Francesco
- Cojocarasu Oana Zveltlana
- Colosimo Maree
- Contu Antonio
- Corona Jorge
- Cortijo Lucia Gonzalez
- Crowley Clare
- Cruciani Giorgio
- Csejtei Andras
- Cubells Laia Garrigos
- Curescu Stefan
- Cussac Antonio Llombart
- Dagada Corinne
- Dalenc Florence
- Damasceno Margarida
- Davis Ruth
- De Aranguiz Blanca Hernando Fernandez
- de Jongh F. E.
- De Laurentiis M.
- de Laurentiis Michele
- de Placido Sabino
- de Valk Bart
- Dejthevaporn Thitiya Sirisinha
- Del Piano Francesco
- Del Prado Purificacion Martinez
- Demetriou Georgia Savva
- Dercksen M. W.
- Deryal Mustafa
- Desauw Christophe
- Desmoulins Isabelle
- Devi Beena C. R.
- Dhadda Amandeep
- Dohollou Nadine
- Dominguez Adriana
- Donadio Michela
- Dreosti Lydia
- Droogendijk Helga
- Dvornichenko Viktoria
- Egreteau Joelle
- El Zawahry Heba
- Eldeeb Hany
- Emelyanov Sergey
- Eniu Alexandru
- Eralp Yesim
- Erdkamp Frans
- Errihani Hassan
- Espinosa Paola Morales
- Estevez Laura Garcia
- Fadjari Heri
- Falcone Alfredo
- Farci Daniele
- Farrokh Andre
- Faust Elke
- Fehr Mathias
- Fernandez Ignacio Pelaez
- Fernando Gracieux
- Ferrandiz Cristina Llorca
- Ferrari Marcela
- Ferrero Jean-Marc
- Filip Dumitru
- Filipovic Sladjana
- Foa Cyril
- Forcignanò R. Chiara
- Fountzilas George
- Franco Sandra
- Fraser Judith
- Frassoldati Antonio
- Freedman Ori
- Friedlander Michael
- Friedrichs Kay
- Gaete Alejandro Andres Acevedo
- Gaion Fernando
- Gallego Pedro Jimenez
- Gamucci Teresa
- Ganju Vinod
- Garcia Saenz Jose Angel
- Garcia Sanchis Laura
- Garcia Mirta
- Garcia Vanesa Quiroga
- Garcia Yuraima
- Garcia-Palomo Perez Andres
- Garidi Reda
- Garrido Maria Lomas
- Gasnault Laurent
- Giotta Francesco
- Gligorov J.
- Gligorov Joseph
- Gogas Helen
- Gordana Kecman
- Govender Poovandren
- Graf Heiko
- Grecea Daniela
- Green Michael
- Griesshammer Martin
- Grischke Eva-Maria
- Guardiola Emmanuel
- Gugic0 Damir
- Hall Julia
- Hamizi Salima
- Harb Mohammed
- Haringhuizen Annebeth
- Hauser Nik
- Hegg Roberto
- Heider Andrea
- Helena Vanessa
- Hennessy Bryan
- Henschen Stephan
- Hernandez Carlos Alberto
- Hernandez-Monroy Cesar Estuardo
- Hesse Tobias
- Hickish Tamas
- Hogg Martin
- Horvath Zsolt
- Howe Theresa
- Huang Chiun-Sheng
- Huinink Daan Ten Bokkel
- Hänle Claudia
- Idris Mohamed
- Isikdogan Abdurrahman
- Ismael Gustavo Fernando
- Jackisch Christian
- Jacquin Jean-Philippe
- Jaloudi Mohammed
- Jarcau Rosana
- Jaso Laura Murillo
- Jaubert Dominique
- Jañez Noelia Martinez
- Jinga Dan-Corneliu
- Joffe Jonathan
- Jolimoy Geneviève
- Jordaan Johannes Petrus
- Joy Anil Abraham
- Jung K. H.
- Jung Kyung Hae
- Juozaityte Elona
- Kakolyris Stylianos
- Kelleher Muireann
- Kelly Cathy
- Kelly Stephen
- Kendall Anne
- Kersten Christian
- Killander Fredrika
- Kisro Jens
- Kocsis Judit
- Kok T. C.
- Korbenfeld Ernesto Pablo
- Koroveshi Dhurata
- Kovcin Vladimir
- Kristeleit Hartmut
- Krzemieniecki Krzysztof
- Kuemmel Sherko
- Kulkarni Swati
- Kurnianda Djohan
- Köhler Andreas
- Lampe Dieter
- Lantzsch Tilmann
- Largillier Remy
- Latos Kunibert
- Lauer S.
- Leduc Bernard
- Lee Keun Seok
- Lee Soo Hyeon
- Leskova Jaroslava
- Lessa Alvaro Edson
- Lex Benno
- León María Isabel
- Lichinitser Mikhail
- Liedtke Cornelia
- Lion Lorena
- Litwiniuk Maria
- Livi Lorenzo
- Lopez Norberto Batista
- Lorenzo Jose Ponce
- Lorusso Vito
- Los Maartje
- Luedders Doerte
- Lumsden Graeme
- Lungulescu Dan
- Macmillan Craig
- MacPherson Iain
- Madretsma Stanley
- Maicas Maria Dolores Torregrosa
- Maiello Evaristo
- Maintz Christoph
- Malik Zafar
- Maneechavakajorn Jedzada
- Mangel László Csaba
- Manikhas Alexey
- Mano Max
- Marcano Dalila
- Marchetti Paolo
- Mardiak Jozef
- Mariani Gabriella
- Martin Michael
- Martin Philippe
- Martorell Antonia Perello
- Marty Chantal Bernard
- Masood Nehal
- Matamala Luis
- Mavroudis Dimitris
- Mañas José Juan Illarramendi
- Melichar Bohuslav
- Melis Adrien
- Mendoza René Lazaro González
- Mezei Klara
- Mineur Hortense Laharie
- Mion Marta
- Misurová Etela
- Mithal Natasha
- Mjaaland Ingvild
- Monge Jeremy
- Morales Luis Antonio Fernandez
- Morelle Alessandra
- Moscetti Luca
- Moullet Isabelle
- Mousseau Mireille
- Mruk Andrzej
- Murillo Serafin Morales
- Musolino Antonino
- Muñoz Rene
- Müller Andreas
- Müller Volkmar
- Nagy Zsuzsanna
- Nasim Saira
- Nave Monica
- Neal Anthony
- Neciosup Silvia
- Nedovic Jasmina
- Ng Raymond
- Ngan Roger
- Nguyen Suzanne
- Nogueira Jose Alberto
- North Richard
- O'Connor Miriam
- Oprean Cristina Marinela
- Orfeuvre Hubert
- Osegueda Finlander Rosales
- Overkamp Friedrich
- Pagani Olivia
- Panwar Udaiveer
- Papadimitriou Christos
- Papandreou Christos
- Papazisis Konstantinos
- Park-Simon Tjoung-Won
- Passmann-Kegel Heike
- Patterson Kevin
- Paul Marion
- Pazzola Antonio
- Pedrazzoli Paolo
- Pesic Jasna
- Petit Thierry
- Phua Vincent
- Pienkowski Tadeusz
- Pigi Andrea
- Pilarte Rafael Gutierrez
- Pivot X.
- Pivot Xavier
- Popescu Razvan
- Prady Catherine
- Prausová Jana
- Prayogo Nugroho
- Prechtl Anita
- Priou Frank
- Proctor Andrew
- Proctor Steven John
- Rabaglio Manuela
- Raj Sanjay
- Ramiro Alejandro Juarez
- Ramos Glenda
- Rashid Kamran
- Rauch Daniel
- Reategui Rocio
- Redfern Andrew
- Rehman Shazza
- Richardson Gary
- Ringsdorf Uta
- Rodriguez Robinson
- Romero Jose Luis Alonso
- Roque Fernando
- Rosales Adolfo Murias
- Runnebaum Ingo
- Ruth Sylvia
- SafeHer Study Group
- Sakaeva Dina
- Salat Christoph
- Sandri Ines
- Santiago Santiago Gonzalez
- Santoro Armando
- Santos Juan Matos
- Sawrycki Piotr
- Scatchard Kate
- Scheffen Iris
- Schilling Jörg
- Schlatter Christina
- Schmatloch Sabine
- Schmidt Marcus
- Schneeweiss Andreas
- Schrader Iris
- Seetalarom Kasan
- Seipelt Gernot
- Senol Coskun Hasan
- Seo Jae Hong
- Sevinc Alper
- Shah Mazhar
- Sherwin Elizabeth
- Shing M.
- Shirinkin Vadim
- Shparyk Yaroslav
- Simon Elke
- Simon Helene
- Simon Sonia Pernas
- Sims Eliot
- Singer Julian
- Slomian Grzegorz
- Smilde T. J.
- Smith Sarah
- Sohn Joo-Hyuk
- Somwangprasert Areewan
- Stanculeanu Dana Lucia
- Stefani Laetitia
- Stefek Andrea
- Stickeler Elmar
- Strebel Heinrik Martin
- Stroyakovskiy Daniil
- Svensson Jan Henry
- Szanto Janos
- Tahir Saad
- Takac Iztok
- Tanggo Eddie Herman
- Taylor Wendy
- Teoh Darren
- Terwogt Jetske M. Meerum
- Thill Marc
- Tienghi Amelia
- Timcheva Konstanta
- Tio Joke
- Tomczak Piotr
- Tomova Antoaneta
- Torres Roberto
- Tsakova Maya
- Tsalic Medy
- Tuczek Anna
- Turdean Maria
- Urrego Marcela
- Uwer Lionel
- Uygun Kazim
- Valdiviezo Natalia
- van de Wouw A. J.
- van den Berkmortel Franchette
- van den Bosch J.
- van der Padt Annemieke
- van der Velden Annette
- van Rossum-Schornagel Quirine Clementine
- Van Thuan Tran
- van Warmerdam Laurence
- Vasovic Suzana
- Veersamy Petrosian
- Vega Jose Manuel Lopez
- Vera Luis
- Verrill M.
- Verrill Mark
- Villanueva Silva Maria Jose
- Villarreal Garza Cynthia Mayte
- Voitko Nataliia
- von der Assen Albert
- Vongsaisuwon Mawin
- Vrbanec Damir
- Vyzula Rostislav
- Wagnerova Maria
- Wang Hwei-Chung
- Wardley Andrew
- Warm Mathias
- Waters Simon
- Weigel Michael
- Wheatley Duncan
- Wischnik Arthur
- Wist Erik
- Wojcinski Sebastian
- Wright Kathryn
- Yanez Eduardo
- Yeo Winnie
- Youssef Ali
- Yu Jyh-Cherng
- Yucel Eftal
- Yucel Idris
- Yuille Frances
- Yumuk Fulden
- Yusof Mastura
- Zaman Khalil
- Zekri Jamal
- Ziegler-Löhr Katja
- Zlatareva-Petrova Ani
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
- Author
- Abdi Ehtesham
- Abraham Jean
- Abreu Miguel
- Adams Sylvia
- Aktan G.
- Al Baghdadi Tareq
- Allerton Rozenn
- Allison Magnuson
- Altena Renske
- Alés Martínez Jose Enrique
- Anampa Mesias Jesus
- Andreopoulou Eleni
- Ansari Bilal
- Antill Yoland
- Aogi Kenjiro
- Aragones Antonia Marquez
- Arahmani A.
- Armstrong A.C.
- Armstrong Anne
- Armstrong Deborah
- Armstrong Deborah
- Arnedos M.
- Arrick Bradley
- Asaad Shonda
- Aydogdu Mustafa
- Baez-Diaz Luis
- Bahadur Shakeela
- Bakker Sandra
- Balmaña J.
- Barrett Sophie
- Bartsch Rupert
- Bañuelos Juan Cueva
- Bear Harry
- Bechtner Christina
- Bella Santiago
- Bergh J.
- Bermejo de las Heras Begoña
- Bernardo Antonio
- Bertrán Ana Santaballa
- Bianchini Giampaolo
- Biganzoli Laura
- Blajman Cesar
- Bliss J.
- Boadle David
- Bobolis Kristie
- Bonetti Andrea
- Bordeleau Louise
- Borges Virginia
- Borley Annabel
- Borms Marleen
- Borrego Manuel Ruiz
- Boyle L.E.
- Braga Sofia
- Brain Etienne
- Braybrooke Jeremy
- Brescia Frank
- Brufsky A.M.
- Brufsky Adam
- Bucci Eraldo
- Burhani Nafisa
- Busch Steffi
- Cameron D.
- Campbell C.
- Cannon George
- Cannon George
- Canon Jean-Luc
- Cao María González
- Cardoso Catarina
- Cardoso Fátima
- Carlson Jay
- Carlson Jay
- Carney Jennifer Fu
- Carrasco Fernando Henao
- Casa-Nova Mafalda
- Cescon Terrence
- Chacón López-Muñiz José Ignacio
- Chae Yee Soo
- Chakiba-Brugere Camille
- Chalchal Haji
- Chan Stephen
- Chang Brian
- Chang Yuan-Ching
- Charles William
- Chen Shang-Hung
- Chen Shin-Cheh
- Chen Shou-Tung
- Chiu Chang-Fang
- Cho Eun Kyung
- Chowdhury Nabila
- Chung Wei-Pang
- Ciccarese Mariangela
- Ciruelos Gil Eva María
- Cobleigh Melody
- Cole John
- Cole John
- Cole John
- Cole John
- Colleoni M.A.
- Colleoni Marco
- Company Jesús Alarcon
- Conejero Raquel Andrés
- Conibear John
- Constanzo Maria Victoria
- Conte Pierfranco
- Copson Ellen
- Copur Mehmet
- Cortesi Laura
- Cortijo Lucía González
- Cretella Elisabetta
- Cristofanilli Massimo
- Crusades Gema Llort
- Cui K.
- Curtit Elsa
- Dakhil Shaker
- Dakhil Shaker
- Dalivoust Philippe
- Darsow Maren
- Dayao Zoneddy
- de Boer Maaike
- de la Haba Juan
- de Laurentiis Michelino
- Decker Thomas
- Dedes Konstantin
- Delaloge S.
- Delaloge Suzette
- Delgado Mingorance Juan Ignacio
- Deming Richard
- Denittis Albert
- Deryal Mustafa
- Desbiens Christine
- Deveras Ruby Anne E.
- Dewar Joanna
- Dewitz Thomas
- Dieterich Max
- Domchek S.M.
- Domchek Susan
- Doster John
- Doyle Thomas
- Duhoux François
- Durna Lara
- Egle Daniel
- Einhorn Harvey
- Eisen A.
- Eisen Andrea
- Eisenberg Peter
- Ellis Robert
- Elsafy F.
- Emde Till-Oliver
- Erdkamp Franciscus
- Estevez Laura García
- Extra Jean-Marc
- Faller Bryan
- Fan Z.
- Fan Zhimin
- Fasching Peter
- Fehm Tanja
- Fein L.E.
- Fein Luis
- Ferrario Cristiano
- Ferrero Jean-Marc
- Feusner James
- Fielding A.
- Flaum Lisa
- Flynn Patrick
- Flynn Patrick
- Ford J.M.
- Forstmeyer Dirk
- Friday Bret E.B.
- Friedlander Michael
- Friedman S.
- Fu Peifen
- Fuchs David
- Ganz Patricia
- Garber J.E.
- Garber Judy
- Garber Judy
- García Sáenz José Ángel
- Gayle Arlene
- Gebbia Vittorio
- Gelber R.D.
- Gelmon K.A.
- Gelmon Karen
- Gelpi Judith Balmaña
- Geng Cuizhi
- George Mathew
- Gerds Aaron
- Geyer C.E.
- Giacchetti Sylvie
- Gianni L.
- Gianni Lorenzo
- Gil Amaryllis
- Gnant M.
- Gomez Elena Álvarez
- González-Santiago Santiago
- Goodwin Annabel
- Gori Stefania
- Grafe Andrea
- Graffunder Gerd
- Gratet Alain
- Greil Richard
- Grischke Eva Maria
- Gross Howard
- Gross Howard
- Gross Howard
- Gross Howard
- Gross Howard
- Gröll Isolde
- Göhring Uwe-Jochen
- Hackmann John
- Hahn Antje
- Hahn Olwen
- Hallbeck Anna-Lotta
- Hanson David
- Harbeck Nadia
- Hardy-Bessard Anne-Claire
- Harkness Cameron
- Haslbauer Ferdinand
- Hauke Ralph
- Hauke Ralph
- Hayward Richard
- Heibl Sonja
- Heijns Joan
- Heinrich Bernhard
- Helfgott Ruth
- Herbolsheimer Pia
- Hesse Tobias
- Hickish Tamas
- Hilton Christie
- Hoffmann Oliver
- Hofstatter Erin
- Hofstatter Erin
- Hofstatter Erin
- Hollingsworth S.J.
- Hoskins Kent
- Hou Ming-Feng
- Huang Chiun-Sheng
- Huober Jens
- Hurwitz Jane
- Huynh Chanh
- Huzarski Tomasz
- Höffkes Heinz-Gert
- Im S.-A.
- Im Seock-Ah
- Isaacs Claudine
- Ishida Kazushige
- Ito Mitsuya
- Iwata Hiroji
- Jackisch Christian
- Jacot William
- Jager A.
- Jager Agnes
- Janni W.
- Jañez Noelia Martínez
- Jegannathen Apurna
- Jens-Uwe Blohmer Jan Schröder
- Jerusalem Guy
- Jiang Zefei
- Jiménez Miguel Martín
- Johannsson Oskar
- Jones Catherine
- Jones Cheryl
- Joris Sofie
- Joshi Abhishek
- Jubelirer Steven
- Julian Thomas
- Jung K.H.
- Jung Kyung Hae
- Jurado Josefina Cruz
- Jóhannsson Ó. Þ
- Kaen Diego
- Kalinka Ewa
- Kalra Maitri
- Kannourakis George
- Karwal Mark
- Kast Karin
- Kaufman B.
- Kaufman Bella
- Kelleher Muireann
- Khosla Pam
- Kim Jee Hyun
- Kinoshita Takayuki
- Klare Peter
- Kolberg Hans-Christian
- Korde L.
- Krabisch Petra
- Kroep Judith
- Kurian Sobha
- Kuzma Charles
- Kühn Thorsten
- Kümmel Sherko
- Kümmel Sherko
- l'Haridon Tiffenn
- Lakhani S.R.
- Lambiase Elyse
- Landherr László
- Lanza Angels Arcusa
- Lazzaro Mauricio Fernández
- Ledwon Peter
- Lee Keun Seok
- Lee Kyoung Eun
- Lerzo Guillermo
- Lescure Álvaro Rodríguez
- Leu Kirsten M.H.
- Levine Edward
- Levitt Nicola
- Liao Ning
- Linderholm B.
- Linderholm Barbro
- Liu T.-W.
- Lo Shelly
- Loibl S.
- Loman N.
- Loman Niklas
- Lortholary Alain
- Lu Min
- Lu Min
- Lucas P.C.
- Luce Sylvie
- Lévy Christelle
- López Isabel Álvarez
- Mackey John
- Mackiewicz Jacek
- Mahtani Reshma
- Mahtani Reshma
- Mailliez A.
- Mailliez Audrey
- Mansoor Abdul
- Marcom Paul
- Marmé F.
- Martinez de Dueñas E.
- Martinez Lourdes Calvo
- Martínez de Dueñas Eduardo
- Masuda Norikazu
- Mau Christine
- Mccarron Edward
- Mccarthy Nicole
- Mcconnell R.
- Mege Alice
- Meisel Jane
- Menter Alex
- Merkel Douglas
- Mita Monica
- Molins Agusti Barnadas
- Mosconi Anna Maria
- Mouret-Reynier Marie-Ange
- Mukai Hirofumi
- Murillo Serafín Morales
- Murray Nicholas
- Müller Volkmar
- Nagy T.
- Nagy Tünde
- Nakamura Rikiya
- Nakamura Seigo
- Nakayama Takahiro
- Nangia Julie
- Naoi Yasuto
- Nave Mónica
- Neven Patrick
- Niraula Saroj
- Noeding Stefanie
- Noesselt Thomas
- Novak Urban
- Nowecki Zbigniew
- O'Connor Brian
- Ochoa Augusto
- Ochoa Augusto
- Ofori Samuel
- Olabisi Foluso
- Oliff Ira
- Openshaw Thomas
- Openshaw Thomas
- Openshaw Thomas
- Ortega Adela Fernández
- Ortega Ana Laura
- Osaki Akihiko
- Padró Josep Gumà
- Paepke Stefan
- Pang D.
- Pang Da
- Papadimitriou Konstantinos
- Park Y.H.
- Park Yeon Hee
- Park-Simon Tjoung-Won
- Parton M.
- Parton Marina
- Pasterk Claudia
- Patel Tejal
- Patocskai Erica
- Penzinger Monika
- Perren Timothy
- Perrin Christophe
- Petit Thierry
- Phillips K.-A.
- Phillips Kelly-Anne
- Piccart M.
- Pilnik Norma
- Pinotti Graziella
- Polikoff Jonathan
- Polikoff Jonathan
- Polikoff Jonathan
- Polikoff Jonathan
- Polikoff Jonathan
- Polikoff Jonathan
- Potenberg Jochem
- Pottier Virginie
- Prady Catherine
- Pristauz-Telsnigg Gunda
- Puthillath Ajithkumar
- Qamar Rubina
- Qamar Rubina
- Qamar Rubina
- Qamar Rubina
- Quaghebeur Claire
- Quiroga Vanesa
- Raben Adam
- Radford James
- Rai Yoshiaki
- Ramaswamy Bhuvaneswari
- Rastogi P.
- Rautenberg Beate
- Razaq W.
- Razaq Wajeeha
- Rea Daniel
- Reeder Jennifer
- Rhiem Kerstin
- Riseberg David
- Robin Erwin
- Rodríguez César
- Rohatgi Nitin
- Rom Joachim
- Roodenbeke Daphné T’kint De
- Ross L.
- Rossi G.
- Rovito Marc
- Roylance Rebecca
- Ruddy Kathryn
- Ruggeri Enzo Maria
- Rumpold Holger
- Ryan Matthew
- Salat Christoph
- Salkeni Mohamad
- Sami Amer
- Santisteban Marta
- Sarosiek Tomasz
- Sato Nobuaki
- Schallenkamp John
- Schmatloch Sabine
- Schmidt M.
- Schmidt Marcus
- Schmutzler R.
- Schott Anne
- Schreiber Carsten
- Seaward Samantha
- Seaward Samantha
- Seeger Grant
- Senkus E.
- Senkus Elżbieta
- Sevelda Paul
- Shao Z.
- Shao Zhimin
- Sharma P.
- Sharma Priyanka
- Sharma Ruby
- Shen Kunwei
- Shenk Robert
- Shenk Robert
- Shenk Robert
- Siegel Robert
- Siggelkow Wulf
- Sigurdson Elin
- Silander Gustav
- Simon Hélène
- Simon Michael
- Singer C.F.
- Singer Christian
- Smith Ron
- Sohn Joo Hyuk
- Song Chuangui
- Sonke G.S.
- Sonke Gabe
- Soori Gamini
- Specht Jennifer
- Spector David
- Steen Preston
- Stefek Andrea
- Stickeler E.
- Stickeler Elmar
- Stockham Abigail
- Storniolo Anna M.V.
- Strasser-Weippl Kathrin
- Stöger Herbert
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
- Sugimoto Takeki
- Sui Xingwei
- Sumida Kenneth N.M.
- Sumida Kenneth N.M.
- Sumrall Bradley
- Sun Q.
- Sun Qiang
- Słowińska Anna
- T Benjamin
- Taboada M.
- Takada Masahiro
- Takahashi Masato
- Takano Toshimi
- Tan Antoinette
- Tato-Varela Sara
- Telli Melinda
- Tennevet I.
- Tennevet Isabelle
- Terhaag Jürgen
- Thiel Irene
- Thomalla Jörg
- Thomssen Christoph
- Tiley Susan
- Tinchon Christoph
- Tio Joke
- Tkaczuk Katherine H.R.
- Toi M.
- Tokuda Yutaka
- Tokunaga Eriko
- Tomé Oliver
- Tondini Carlo
- Toppmeyer Deborah
- Tormo Salvador Blanch
- Torres Antonio Antón
- Toyama Tatsuya
- Traina T.A.
- Tredan Olivier
- Trehan Shruti
- Tseng Ling-Ming
- Tsugawa Koichiro
- Tutt A.N.J.
- Tutt Andrew
- Uleer Christoph
- Unnikrishnan Madhu
- Urquhart Alexander
- Uziely Beatrice
- Vachhani Hetal
- Vakhariya Cynthia
- Valdes-Albini Frances
- van der Westhuizen Andre
- van Haelst Carol
- Vanderwoude Amy
- Varadarajan Ramya
- Varela Mirta
- Venat-Bouvet Laurence
- Verusio Claudio
- Viale G.
- Villaró Gemma Viñas
- Virani Shamsuddin
- Vogel Victor
- von Wachenfeldt Väppling Anna
- Wade James
- Wade James
- Wagner Harald
- Waisman James
- Wang Shui
- Wang Yongsheng
- Watanabe Junichiro
- Weigel Michael
- Weltermann Angsar
- Weniger Steffi
- Wette Viktor
- Wilbur Deborah
- Wilkinson Mary
- Winter Matthew
- Wolf Sütterlin Marc
- Wong Derrick
- Wong Lucas
- Wood Marie
- Wood Marie
- Woodward Natasha
- Wüllner Michaela Penelope
- Xu Binghe
- Yamauchi Hideko
- Yan Fengting
- Yanagita Yasuhiro
- Yang H.
- Yang Hongjian
- Yeh Dah-Cherng
- Yerushalmi R.
- Yerushalmi Rinat
- Yothers G.
- Yu Jyh-Cherng
- Zahm Dirk
- Zakalik Dana
- Zamagni Claudio
- Zaman Khalil
- Zarba Juan Jose
- Zera Richard
- Zera Richard
- Zhang J.
- Zhang Jin
- Zheng Hong
- Zhuo Ying
- Zimbler Harvey
- Zoppoli G.
- Öhler Leopold
- Španić T.
- Publication venue
- Elsevier
- Publication date
- 01/12/2022
- Field of study
International audienc
Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗
- Author
- Abderrahim Azzouzi
- Abroug F.
- Achille Kouatchet
- Achim Lunkeit
- Adam Mikstacki
- Aguilera García
- Ahmed Sbihi
- Ai-Chin Cheng
- Ainhoa Rosselló
- Alain Mercat
- Alan Javier Zazu
- Alberto Belenguer
- Alberto Deicas
- Alberto Marino
- Alberto Soler
- Alejandro Algora
- Alejandro Arroliga
- Alejandro de la Serna
- Alejandro Gómez
- Alejandro Raimondi
- Alejandro Risso
- Alfonso Moreno
- Alfonso Muñoz
- Alfredo Padrón
- Alfredo Vasquez-Sandoval
- Ali Aydım Altunkan
- Ali Zeggwagh A.
- Aline Camile Yehia
- Alistair Nichol
- Allan Walkey
- Allison Bone
- Aloísio Marques do Nascimento
- Alvaro van Bommel
- Amalia Martínez de la Gandara
- Amber Monson
- Ambrogio Sansone
- Amee Patrawalla
- Amin P.
- Amine Ali Zeggwagh
- Amparo Ferrandiz
- Amy Waters
- Ana Carolina Caballero
- Ana Esther Trujillo
- Ana Villagrá
- Anders Aneman
- Andrea Gimenez
- Andrea Matte
- Andrea Neville Cracchiolo
- Andreas Schwartz
- Andreas Viehöfer
- Andrei Piontek
- Andrew Bersten
- Andrew Davies
- Andrew Davies
- Andrew Davies
- Andrew Steel
- Andrey Yaroshetskiy
- Anette Mortensen
- Anitha Shenoy
- Ankur Devendra Bhavsar
- Annunziata Mattei
- Anthony Saleh
- Antonina Pigna
- Antonino Giarratano
- Antonio Anzueto
- Antonio Braschi
- Antonio Corcione
- Antonio García-Jiménez
- Antonio Maestre
- Antonio Pesenti
- Antonio Raso
- Antonio Reyes
- Antonio Villa Delgado
- Antonio Viñuales
- Anzueto A.
- Arianna Boggero
- Ariel Chena
- Armando Pedulla'
- Arnaud W Thille
- Ashley Ellis
- Ashley Ellis
- Asisclo J Villagómez Ortiz
- Auke Reidinga
- Ayed Samia
- Barbara Tamowicz
- Barrios D.
- Bas M Kors
- Begoña Balerdi
- Benoit Veber
- Bernabé Álvarez
- Bersten A.
- Bert Beishuizen
- Besbes Mohamed
- Bilge Çetin
- Bin Du
- Bin Du
- Bin Yu
- Bing Sun
- Birgitte Viebaek
- Bladimir Alejandro Gil
- Bo Broberg
- Bo Wang
- Boris Villamagua
- Brian Sherman
- Bruno Bonaccorsi Fernandino
- Bruno do Valle Pinheiro
- Bryan Beatty
- C Canevet
- Cakar N.
- Cameron Knott
- Camilo Pizarro
- Carlo Alberto Acosta
- Carlos Alberto Studart Gomes
- Carlos André Correia Casado
- Carlos Andrés Díaz
- Carlos Gallego
- Carlos Marian Crespo
- Carlos Robles-Arias
- Carmelo Dueñas
- Carmen Campos
- Carolina Gímenez-Esparza
- Carolina Lorencio
- Cartan Costello
- Catherine Simmonds
- Cayce Strength
- Cayetano Galetti
- Cecilia Carbayo
- Cecilia Hermosa
- Cecilia Pereyra
- Cesar Enciso
- Cezar Mihailescu
- Chabu Coronado
- Chafrina Marie Olay
- Chang Liu
- Chantal Hogan
- Charki Haimeur
- Chau Chin Man
- Chen Chin-Ming
- Chengmin Yu
- Cheromi Sittambalam
- Cheryl Cuzner
- Cheryl Ethier
- Chiara Verga
- Christian Frenkel
- Christian Putensen
- Christopher MacIsaac
- Christopher Spradley
- Chuanyun Qian
- Claire Cattigan
- Claire Reynolds
- Clara Laplaza Eva Regidor
- Clara Pacheco
- Claudia Diaz
- Claudia Olvera-Guzman
- Craig A Piquette
- Craig Cernosek
- Crissie De Spirito
- Crissie Despirito
- Cristian Casabella
- Cristian Cevallos
- Cristina Orlandi
- Cristina Santos
- César Antonio Maquilon
- César Aragón
- César Cruz Lozano
- César Pérez-Calvo
- Damian Violi
- Dana K Soetaert
- Daniel Duarte
- Daniel Fontaneda
- Daniel Vargas
- Daniel Weiss
- David Freire
- David Milliss
- Davide Chiumello
- Daxing Yu
- Debiao Song
- Deborah Barge
- Deborah Cook
- Deepak Govil
- Del-Sorbo L.
- Denice Wells
- Dennis Bergmans
- Dhruva Chaudhry
- Di Russo
- Diane Mackle
- Dianne Hill
- Dianne Stephens
- Dietrich Henzler
- Dimitros Matamis
- Dimple Tejwani
- Dinalva Aparecida Gomes
- Do Danh Quynh
- Dolores Vila
- Dongpo Jiang
- Dorothée Carpentier
- Du B.
- Edgard Luna
- Edgardo E Tabhan
- Edgardo Nuñez
- Edoardo De Robertis
- Eduard Bootsma
- Eduardo Almeida
- Eduardo Fonseca Sad
- Edward Nicolayenko
- Eileen Gilder
- Elena Gallego
- Elena Parreño
- Eleni Antoniadou
- Elias Caragna
- Elisa Estenssoro
- Elisha Fulton
- Elisha Matheson
- Ellen Kinkel
- Emily Stern
- Enrique Maraví
- Enrique Piacentini
- Erika Mannelli
- Erin Braden
- Erna Alberts
- Erwin J Oei
- Esteban A
- Eugenio Palazón
- Eva Benveniste
- Eva Manteiga
- Fabien Grelon
- Fabien Soulis
- Fabricio Picoita
- Fachun Zhou
- Falk Hildebrandt
- Fang Xu
- Farhad N Kapadia
- Fausto Fialho Moura
- Federica Antonicelli
- Federica Tallarini
- Federico Gordo
- Fekri Abroug
- Feng Li
- Fernando Antônio Botoni
- Fernando Fernández
- Fernando Lambert
- Fernando Lipovestky
- Fernando Pérez
- Fernando Ríos
- Fernando Saldarini
- Fernando Sánchez
- Fernando Villarejo
- Fernando Villarejo
- Filomena Faria
- Forbes McGain
- Francesca Frigieri
- Francesco Idone
- Francesco Mojoli
- Francisco Criado
- Francisco Guerrero
- Francisco Lucena
- Francisco Manzano
- Francisco Molina
- Francisco Ortuño
- Frank Torres
- Franklin Villegas
- François Collet
- Freddy Sandy
- Freddy Sánchez
- Frederico Costa Val Barros
- Frederico Rodrigues Anselmo
- Frutos-Vivar F.
- Frédéric Bellec
- Félix Lacoma
- Gabriel D Empaire
- Gaetano Perchiazzi
- Gang Li
- Gary Kinasewitz
- Gary Kinasewitz
- Gastón Pittini
- Gaëtan Bedunaeu
- Gee Young Suh
- Gemma Rialp
- Geneva Tatem
- Geng Zhang
- Genis Carrasco
- George Liziamma
- George Lukas
- Gerardo Filippa
- Gilda Diaz-Fuentes
- Gina Quinde
- Giorgia Citterio
- Giorgio Tulli
- Gonzalez M.
- Gonzalo Javier Ríos
- Graciela Elizabeth
- Graciela Franca
- Graeme Duke
- Gregory A Schmidt
- Guillaume Marcotte
- Guillermo Chiappero
- Guillermo Cueto Robledo
- Guillermo Falconí
- Guillermo Muñiz
- Guillermo Ortiz
- Gustavo Badariotti
- Gustavo Jannello
- Gustavo Morales Muñoz
- Gustavo Paredes
- Géraldine Dessertaine
- Haibo Qiu
- Hannah Mathers
- Hans-Henrik Bülow
- Harald Fritz
- Harry P P M Gelissen
- Heinrich Paulus
- Heinz Kerger
- Helen Rodgers
- Helen Wong
- Heloisa Castro
- Henry Caballero
- Hergen Buscher
- Hernan Nunia
- Hernán Nuñez
- Hong Pu
- Hongyang Xu
- Hongyuan Lin
- Howard Connor
- Hugo Capponcelli
- Hugo Urbano
- Hye Sook Choi
- Ian Carrasco
- Ian Moore
- Ian Seppelt
- Ilaria Curro'
- Ilaria Maria Mastromauro
- Imed Chouchene
- Imogen Mitchell
- Ingrid van den Hul
- Ingrid Von der Osten
- Inmaculada Vallverdú
- Irene Aragão
- Irene Dot
- Irene Watpool
- Islem Ouanes
- Ismail Kati
- Itziar Mintegui
- Ivano Aprile
- Jacinto Baena
- Jackeline Coello
- Jan Dittmann
- Jan Friedrich
- Jan Mehrtens
- Jane Thomas
- Janine Dias Alves
- Jasmin Board
- Jasmin Board
- Jasmin Board
- Jason Fletcher
- Javier Blanco
- Javier Castañeda
- Javier Cebrián
- Javier Díaz Domínguez
- Javier García-Alonso
- Javier González-Robledo
- Javier Horacio Álvarez
- Javier Hurtado
- Javier Ladape Martinez
- Javier Ruiz
- Je Hyeong Kim
- Jean-Christophe M Richard
- Jeff Presneill
- Jeffrey Singh
- Jennifer Germain
- Jennifer Goodson
- Jennifer Holmes
- Jennifer Twombley
- Jenny Dennett
- Jens Brushoj
- Jens Buettner
- Jesús Sánchez
- Jesús Sánchez-Ruiz
- Jian Huang
- Jianbiao Meng
- Jianguo Li
- Jianhong Fu
- Jianying Guo
- Jiaqiong Li
- Jibaja M.
- Jin Hwa Lee
- Jin Young An
- Jinghua Wang
- Jiuzhi Zhang
- Joachim Hartung
- Joan Maria Raurich
- Joana Silvestre
- Joanne Sutton
- Jodi Brown
- Johannes Busch
- John Durning
- John Myburgh
- John Oropell
- John Santamaria
- Jorge Arroyo
- Jorge Gerez
- Jorge Vidal Hernández
- Jorgelina Guyon
- Jose Angel Baltazar Torres
- Josep Maria Sirvent
- José Carlos Versiani
- José Claudio Leo
- José Elizalde
- José Francisco López Baca
- José J Blanco
- José Luis Scapellato
- José Manuel Serrano
- José María Gutiérrez
- José María Montón
- José María Nicolás
- José María Quiroga
- José Miguel Guerrero
- José Salinas
- José Salvador Martínez Cano
- Joyce Okahashi
- Juan Carlos
- Juan Carlos Maurelia
- Juan David Uribe
- Juan Diego Jiménez
- Juan Domingo Fernández
- Juan Guerra
- Juan Pablo Sedano
- Juan Ramón Cortés
- Juanxian Gu
- Judi Tai
- Judith Sagardía
- Julia López-Díaz
- Julian Strati
- Julie Smith
- Julio Osorio
- Julio Pontet
- Julián Hernández
- Jun Jin
- Jörg Haberkorn
- Jörn Schlechtweg
- Karina Bonasegla
- Katherine Davidson
- Kathleen Lilli
- Katty Trelles
- Kelly Choy
- Kerry Canady
- Ki-Suck Jung
- Kim Heus
- Konstantinos Raymondos
- Kwan Ming Chit
- Kyung Chan Kim
- Larry Welder
- Laura Jones
- Laura Sayagues
- Laura Wilson
- Laura Álvarez-Montero
- Lauralyn McIntryre
- Laurent Brochard
- Leanne Boehm
- Lei Chen
- Leila Eckholt
- Leonardo Pazmiño
- Leonie Weisbrodt
- Leticia Rapetti
- Liang Pan
- Lidón Mateu
- Liliana Caipe
- Lisa Julien
- Lisandro Betttini
- Loredana Pitagora
- Lori-Ann Kozikowski
- Lucas Vallejo
- Lucia Capilla
- Luis Fernando Castro Castro
- Luis Gonzalez Mosquera
- Luis González Zambrano
- Luis Marina
- Luis Pablo Cardonnet
- Luis Soto-Germani
- Luis Soto-Román
- Luis Williams
- Lutz Pfeiffer
- Lynette Newby
- M Eugenia
- Madhav Gudi
- Madison Dennis
- Maggiore S. M.
- Manoj K Saxena
- Manuel Jibaja
- Manuel Valledor
- Maoqin Li
- Mar Gobernado
- Marc Fabra
- Marc Lipkus
- Marcela Canola-Mazo
- Marcela Granados
- Marcelo Alcântara Holanda
- Marcelo Choque
- Marcelo Ochoa
- Marcelo Palavecino
- Marco Adversi
- Marco Antônio Ribeiro Leão
- Marco Antônio Soares Reis
- Marco Bezzi
- Marco Escobar
- Marco Gonzalez
- Marco González
- Marco Montes De Oca
- Marcos Delgado
- Marcos Juan Zec
- Marcus Ruecker
- Maria Aparecida Braga
- Maria Del Mar Torres-Perez
- Maria Giannakou
- Maria Wussow
- Mariana Monllau
- Marianna Esposito
- Marin M. D. C.
- Marina Busico
- Mario Acosta
- Mario Alonso Treviño Salinas
- Mario Cancela
- Mario Gómez
- Mario Villabon
- Marisol Rodríguez-Goñi
- Mark Bailey
- Mark Tidswell
- Markus Schappacher
- Marta Beron
- Marta Ferrari
- Marta Ugalde
- Martin Deheza
- Martín Lugaro
- Mary La Pine
- María Belén Yapur
- María Del Carmen de la Torre
- María Elena Pérez-Losada
- María Eugenia González
- María Fernanda García
- María Garitacelaya
- María Isabel Ruiz
- María José Tolón
- María Luisa Navarrete
- María Victoria de la Torre
- María Ángeles Alonso
- María Ángeles Pena
- Matamis D.
- Matthew Kirchner
- Matty Koopmans
- Matías Brizuela
- Mauricio Vinzio
- Maurizio Bottiroli
- Maurizio Raineri Santi
- Maurício Meireles Góes
- Maximillian Ragaller
- Mayur Patel
- Medhat Soliman
- Mehar-Un-Nisa Raja
- Mian Chen
- Michael A Kuiper
- Michael Miletin
- Michael Quintel
- Michela Bombino
- Michele Iannuzzi
- Miguel Fernández-Vivas
- Miguel Lazcano
- Miguel León
- Miguel Llano
- Miguel Ángel González-Gallego
- Mijail Játiva
- Mikhail Kirov
- Mikkel Præst
- Minka Springham
- Miquel Ferrer
- Mirko Belliato
- Mohamed A Saad
- Mohammed Al-Jagbeer
- Monica Rocco
- Monika Holler
- Moo Suk Park
- Mounir Bouaziz
- Mourad Amor
- Muriel A.
- Myriam Montalvo
- Myung-Goo Lee
- Nagarajan Ramakrishnan
- Nahit Cakar
- Neill Adhikari
- Nelson Barros
- Nelson Fonseca
- Nelson Medina
- Nghuyen Ba Tuan
- Nguyen Huu Hoang
- Niall Ferguson
- Nicolas Nin
- Nicole Marinoff
- Nicolás Zamboschi
- Nieves Franco
- Nils Marquardt
- Nin N.
- Norberto Tiribelli
- Norberto Tiribelli
- Norma Beatriz Márquez
- Nuria Alonso
- Oliver Franke
- Olivia Dulfo
- Orla Smith
- Oscar Cluzet
- P Kruska
- P Samaddar
- Pablo Desmery
- Pablo Gómez
- Pang Wing Yan
- Paolo Navalesi
- Pascal Beuret
- Pascual Valdez
- Patricia Albert
- Patricia Jimeno
- Patricia Leung
- Patricia Vogl
- Paul Goldrick
- Paul J Dennesen
- Paul Young
- Paulo Marcal
- Pedro Alzugaray
- Pedro Galdos
- Pedro Jesús Domínguez
- Pedro Rosa
- Pelosi P.
- Penuelas O.
- Pertsas Evangelos
- Peter van der Voort
- Pham Thi Van Anh
- Phil Alkana
- Philippe Berger
- Pierre-Gildas Guitard
- Prachee Sathe
- Pravin Amin
- Priya Nair
- Qing Song
- Qingyuan Zhan
- Qunmei Yao
- Rachael Parke
- Rachel Whyte
- Rafael Blancas
- Rafael Morales
- Rahul Nanchal
- Raju Pusapati
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- Raquel Montoiro
- Raquel Yano
- Raymondos K.
- Raúl de Pablo
- Raúl González
- Raúl Lombardi
- Remzi Iscimen
- Ricardo Buitrago
- Ricardo Martinez Zubieta
- Ricardo Matos
- Rick McAllister
- Rios F.
- Robba C.
- Robert Fowler
- Robyn Klages
- Rodrigo E Gómez-Paz
- Roger Lamoglie
- Rogério de Castro Pereira
- Roland Schneider
- Rolf Dembinski
- Rolf Rossaint
- Rollin Roldán Mori
- Romano Tetamo
- Román Garrido
- Ronald Pairumani
- Ronnie Mantilla
- Rosa Luz López Martínez
- Rosa Sebastián
- Rosa Álvaro
- Rosalba Tufano
- Rosanna Del Giudice
- Rosanna Vaschetto
- Rosario Urbino
- Rovílson Lara
- Rovílson Lara
- Rubens Altair Amaral de Pádua
- Rubén Camargo
- Rui Moreno
- Rupesh Vakil
- Ryan Albert
- Sabriye Guvenc
- Salem Ould Zein
- Salvatore Maurizio Maggiore
- Samer Haj-Bakri
- Samir Abdelhadi
- Samir Sahu
- Samir Vermani
- Sando Chavarria
- Sangeeta Mehta
- Sanjay Dhanuka
- Santiago Ilutovich
- Sara Cabañes
- Schimdt Alejandra
- Sebastian Circo
- Sebastián E Mare
- Serena Azzari
- Serge Heines
- Sergio Cáceres
- Sergio Lasdica
- Seton Henderson
- Shawna Reddie
- Sheila Nainan Myatra
- Shelby Sutton
- Sheree Gare
- Shirley Nelson
- Shouhong Wang
- Silke Frenzel
- Silvia Mareque
- Silvina Borello
- Silvio A Ñamendys-Silva
- Simon J G Hockley
- Simona Beniczky
- Sindhaghatta Venkatram
- Sine Wichman
- Smyth Smith
- Soares M. A.
- Sofía García
- Soraya Puertas
- Srinivas Samavedam
- Stambouli Neji
- Steffen Appel
- Steffen Weber-Carstens
- Stephanie Lubchansky
- Stephen Lapinsky
- Steven Y Chang
- Stevens Salva
- Subhash Kumar Todi
- Sujoy Mukherjee
- Susan Gillen
- Susana Alves Ferreira
- Susana Moradillo
- Susana Temprano
- Susanne Andi Iversen
- Sutherasan Y.
- Sutrisno Gunawan
- Sylvia den Boer
- Tania Caf
- Tarek Dendane
- Tayfun Adanir
- Tejerina E. E.
- Teresa Mut
- Teresa Sánchez de Dios
- Thille A. W.
- Thomas Bein
- Thomas Lipp
- Thomas Moellhoff
- Thomas Steinke
- Thoralf Kerner
- Tiehe Qin
- Tim Coles
- Tim Houlihan
- Timothy D Girard
- Tom Cowlam
- Tony Sutherland
- Tony Williams
- Travis Parry
- Troy Browne
- Tumbass Volker
- Uli Strauch
- Umesh G
- Unase Büyükkoçak
- V J Cardenas Jr
- Valentín Parra
- Valerio Mangani
- Valery Subbotin
- Valle Pinheiro B.
- Valéria de Carvalho Magela
- Vanesa Ramírez
- Vicente Arraez
- Victoria Goñi
- Vincent John Scott
- Vito Marco Ranieri
- Vivek Joshi
- Wajdi Maazouzi
- Walter Brandt
- Walter Seyde
- Wanxia Li
- Wei He
- Wei Yu
- Wei Zhang
- Weihai Yao
- William Rodriguez-Cintron
- Winfried Schubert
- Wolfgang Baier
- Won-Yeon Lee
- Xi Zhu
- Xianyao Wan
- Xiaobo Huang
- Xue Wang
- Yalin Liu
- Yan Kang
- Yangong Chao
- Yaseen Arabi
- Yi Li
- Yi Yang
- Yogeet Kaur
- Yongjie Yin
- Young Suh G.
- Younsuck Koh
- Yu Bai
- Yuan Xu
- Yuhong Guo
- Yun Seong Kim
- Yunxuan Yue
- Zafer Dogan
- Zalatiel Maycotte Luna
- Zaza Cohen
- Zhengxuan Lv
- Zhenjie Hu
- Zhenyang He
- Zhicheng Zhang
- Zhihua Hu
- Zhixiang Li
- Zoltan Szentkereszty
- Zoraida Parra
- Zsolt Molnar
- Ángela Alonso
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/11/2021
- Field of study
OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease
Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19
- Author
- Aalap Chokshi
- Abdelkader Medjahedi
- Abhishek Gupta
- Adam Bernheim
- Adel Allam
- Adelina Sanches
- Adolfo Facello
- Adriana Puente
- Adwait Trivedi
- Afroza Akhter
- Agha Haider
- Ahmad Amro
- Ahmad Ozair
- Ahmed Aljizeeri
- Ahmed Ibrahim
- Ahmed Kandeel
- Ahmed Suliman
- Ajay Vyas
- Albert Flotats
- Alberto Cadena
- Alberto Clemente
- Alberto Cuocolo
- Alberto Gerali
- Alejandro Maldonado
- Alejandro Radzinschi
- Alejandro Zuluaga Santamaria
- Alessandra Scatteia
- Alessia Gimelli
- Alexander Kokov
- Alexandre Volney Villa
- Alexey Ansheles
- Alfredo Rodrigues
- Alia Abdelfattah
- Alicia Camarero
- Alireza Emami-Ardekani
- Aloha Meave
- Alvin Quinon
- Amalia Peix
- Ambedhkar Shantaram Naojee
- Amee Shah
- Amelia Jimenez-Heffernan
- Amit Pursnani
- Amit Sharma
- Amjed Albadr
- Amparo Martinez Monzonis
- Ana Manovel-Sánchez
- Ana Teresa Timoteo
- Anastasia Oikonomou
- Anatoliy Karalkin
- Anda Bularga
- Anders Tjellaug Bråten
- Andor Glaudemans
- Andrea Bruno
- Andrea de Lorenzo
- Andrea Paccagnella
- Andrea Vilela
- Andres Preciado-Anaya
- Andressa Borges
- Andrew Choi
- Andrew Choi
- Andrew J Einstein
- Andrew Tauro
- Andrew Taylor
- Angela Byrne
- Angela Gaudiano
- Animesh Mishra
- Anita Liiver
- Anjali Chelliah
- Anna Baritussio
- Anna Teresinska
- Annette Johnstone
- Anthon Fuisz
- Anthony Samuel
- Anthony Upton
- Antonella Stefanelli
- Antonio Calderón
- Apurva Shrigiriwar
- Apurva Sinha
- Arati Lalchandani
- Aristóteles Ramírez Salazar
- Arjun Ghosh
- Arpakorn Kositwattanarerk
- Artan Goda
- Arturo Romero Acuña
- Arve Jørgensen
- Arvind Sethi
- Aryeh Shalev
- Asela Bustos-Barroso
- Ashwani Sood
- Attila Kovács
- Atul Verma
- Augusto Almeida
- Awadhesh Kumar Sharma
- Azeem Sheikh
- Azita Moalemi
- Barbara Gužic Salobir
- Barry Elison
- Bawinile Hadebe
- Bálint Szilveszter
- Belinda San Juan
- Benjamin Hudson
- Benjapa Khiewvan
- Bernadette Lisske
- Bernard Koch
- Bernardo Spiro
- Bernd Klaeser
- Berry Allen
- Bianca Patrut
- Bin Lu
- Binh Duong Duc
- Bjarne L Nørgaard
- Brenda Mccullough
- Brian Morrissey
- Caiying Li
- Calum Young
- Cameron Foster
- Camila Flores
- Candace Candela
- Carla Gonzalez
- Carla Sousa
- Carlo Joe San Juan
- Carlo Liguori
- Carlo Tedeschi
- Carlos Anselmi
- Carlos Caicedo Zamudio
- Carlos Cruz
- Carlos Eduardo Soares
- Carlos Eduardo Suaide Silva
- Carlos Salvador Navarro Quiroz
- Carmen Concha
- Carole Dennie
- Caroline M Van De Heyning
- Ceferino Gutierrez Mendiguchia
- Cesar Higa Nomura
- Cesar Rene Alducin Tellez
- Chae Moon Hong
- Chanan Moffitt
- Chen Sheng Low
- Chetan Patel
- Chongfu Jia
- Chris Rofe
- Christel Kamani
- Christian Llontop
- Christina Fragkaki
- Christoph Gräni
- Christopher Eduarte
- Chrysoula Fragkiadaki
- Chunxiang Tang
- Cibele Gontijo
- Clare Mckenzie
- Claudia Jaimes
- Claudia T Gutierrez Villamil
- Claudio Marcassa
- Claudio Mesquita
- Claudio Pereyra Sueldo
- Claudiu Stan
- Clothilde Berger
- Cole B Hirschfeld
- Connor Saunders
- Corrado Cittanti
- Cristina Gavina
- Cristina Sebastião Matushita
- Cuba Juan Felipe Batista
- D'Arne Downie
- Dainia Baugh
- Daisuke Sato
- Damayanthi Nanayakkara
- Damiana Vergel
- Daniel Berman
- Daniel Calderón
- Daniel Schere
- Danilo Naves
- Darach O H-Ici
- Daria Ryzhkova
- Dario Pellegrini
- David Cusack
- David German
- David Kassop
- David Kerins
- David Mccreavy
- David Prior
- David Wolinsky
- David Wong
- Dee Nandurkar
- Deepak Subedi
- Denis Agostini
- Derk Verschure
- Diana Paez
- Dianbo Cao
- Diego Alasia
- Diego Bromfman Pianta
- Diego Buchara
- Diego Echazarreta
- Diego Perez de Arenaza
- Dietrich Beitzke
- Dilip Na
- Dilip Patel
- Dinesh Kalra
- Domenico Albano
- Dominique Dabreo
- Donatas Vajauskas
- Donato Mele
- Dora Lenturut-Katal
- Dr Pradosh Kumar Sarangi
- Dragana Sobic Saranovic
- Dustin Thomas
- Edgardo Mastrovito
- Edison Bun
- Edith Chavez
- Edward Nicol
- Edward O'Rourke
- Edward Passen
- Ekaterina Migunova
- Elaine Lui
- Elena Busnardo
- Elena Califaretti
- Elena Kyrozi
- Eli Malkovskiy
- Elia García
- Elisa Mcalindon
- Elisa Milan
- Ellen Ostenfeld
- Elshaymaa Hussein
- Emmy Okello
- Enrique Vallejo
- Erdenechimeg Sereegotov
- Erick Alexánderson-Rosas
- Erik Bieging
- Erika Barragan
- Ernest Madu
- Ervina Shirka
- Erwin Affandi Soeriadi
- Estevan Cabeda
- Estrella Aguilera Hernandez
- Eva Alina Wegner
- Evelina Faragasso
- F Aaysha Cader
- Fabien Hyafil
- Fabio Fernandes
- Fabrizia Gelardi
- Fabrizio Ricci
- Fadi Hage
- Faisal Haque
- Faria Nasreen
- Farouk Mansouri
- Farshad Emami
- Febby Hutomo
- Federica Padovano
- Felix Keng
- Felix Solis
- Fernanda Erthal
- Fernando de Amorim Fernandes
- Fernando Faccio
- Fernando Mut
- Filip Homans
- Filipe Macedo
- Filipe Penna
- Franca Chierichetti
- Francesco Bianco
- Francesco Bovenzi
- Franco Gabriel Busso
- Gabriel Grossman
- Gabriela Melendez
- Gad Abikhzer
- Ganesan Karthikeyan
- Gary Small
- Gaspare Arnone
- Gaurav Sharma
- George Angelidis
- George Kinzfogl
- George Pandos
- Gerd Hinterleitner
- Gi Jeong Cheon
- Giampiero Longo
- Gianluca Spidalieri
- Gianmario Sambuceti
- Giedre Kviecinskiene
- Giovanni Matassa
- Girish Dwivedi
- Giuseppe De Vincentis
- Giuseppe Rubini
- Goleat Gutierrez
- Graham Cole
- Gudrun Feuchtner
- Guido Ventroni
- Guilherme S A Azevedo
- Guilherme Urpia Monte
- Gulnora Rozikhodjaeva
- Gulya Marina
- Gustavo Parisi
- Gustavo Vazquez
- Guzaliya Sayfullina
- Haluk Burcak Sayman
- Hamed Zuhairy
- Hamid Amer
- Hamid Naseer
- Hamza Regaieg
- Hanne Sondergaard
- Hanne-Elin Vassbotn
- Harold Arturo
- Harold Ayetey
- Harpreet Singh
- Hatem Alkadhi
- Hayato Ishimura
- Henrik Engblom
- Henry Bom
- Herwin Speckter
- Hesham Hamdy
- Heshui Shi
- Hideki Otsuka
- Hilman Syawaluddin
- Hiroki Teragawa
- Hiroshi Asano
- Hirotaka Maruno
- Ho-Chun Song
- Hoosen Lakhi
- Horacio Del Riego
- Horacio Glait
- Horacio Rojas
- Htin Zar
- Hugo Campanelli
- Hugo Gallegos
- Hugo Humberto Marçal Filho
- Hui Liu
- Humoud Al Dhuhli
- Ibraim Pinto
- Idan Roifman
- Idrissa Adamou Soli
- Igor Coelho
- Ikenna Erinne
- Ilan Gottlieb
- Ioannis Ntalas
- Ioannis Ntalas
- Irena Mitevska
- Irene Casáns-Tormo
- Irina Itskovich
- Irina Shurupova
- Iryna Noverko
- Isabel Blanco
- Isabel Carvajal-Juarez
- Isabella Bruno
- Ivo Andrade
- Jacqueline Henkel
- James Theuerle
- James White
- Jamie Kitt
- Jan Rasmussen
- Jana Polakova Mistinova
- Jane Cao
- Jason See
- Javier De Haro
- Javier Lopez Diaz
- Jawdat Abdulla
- Jay Layer
- Jeffrey Geske
- Jens Hove
- Jeremy Markowitz
- Jerry Obaldo
- Jesu Krupa
- Jesus Gregorio Medina Verdugo
- Ji-In Bang
- Ji-Young Kim
- Jiang Wu
- Jim Streeter
- Jina Chung
- Jinkang Liu
- Joanne Meaker
- Joao V Vitola
- Joao Vitola
- Johann Christopher
- Johanne Neill
- John Edmond
- John Kennedy
- John Lesser
- John Prior
- John Younger
- John-Paul Carpenter
- Jolanta Kunikowska
- Jonathan Hack
- Jonathan Rodrigues
- Jonathan Tow
- Jonathan Weir-Mccall
- Jordi Broncano
- Jorge Camilletti
- Jose Antonio Serna Macias
- Jose Javier Bustos Rivadero
- Jose Lotti
- Joseph Krepp
- Joseph Lee
- Joseph Weinstein
- José Esparza
- José Ortellado
- Juan Carlos Tirado Alderete
- Juan Erriest
- Juan L Londono
- Juan Lopez-Mattei
- Juan Lopez-Mattei
- Juan Montanez
- Juliana Leal Rocha
- Juliano Fernandes
- Julie Hephzibah
- Julie O'Brien
- Julio Manuel Lewkowicz
- Junichi Sato
- Kae Fukuyama
- Karen Hassen
- Karolina Zareba
- Katarina Milos
- Katarina Nelson
- Kate Hanneman
- Katherine Tweed
- Katherine Zukotynski
- Kathleen Magurany
- Katia Hiromoto Koga
- Kazuya Takehana
- Kelley Branch
- Kelly Anzola
- Kenichi Nakajima
- Kenneth Lee
- Kentaro Takanami
- Kevin Prigent
- Khaled Alfakih
- Khalid Makhdomi
- Khanyisile Hlongwa
- Kim Jasper
- Kim Taubman
- Kimiteru Ito
- Kirill Zhuravlev
- Kirsten Worthington
- Koichiro Fujise
- Konrad Weiss
- Konstantin Zavadovsky
- Kristian Hay Kragholm
- Kristian Øvrehus
- Kyoko Umeji
- Kyoung Sook Won
- Lara Carreira
- Lara Faggi
- Lars C Gormsen
- Lars Thorbjoern Jensen
- Laura Dragonetti
- Laura Evangelista
- Laure Sarda-Mantel
- Lazaro Omar Cabrera
- Leah Strickland
- Leena Robinson Vimala
- Leila Salioni
- Leonardo Sara Da Silva
- Leonie Scholtz
- Leslee J Shaw
- Li Yuan
- Lianggeng Gong
- Lilia M Sierra-Galan
- Lilia Sierra-Galan
- Lino Gonçalves
- Longjiang Zhang
- Lorenzo Sewanan
- Lu Chen
- Luca Mircoli
- Luca Pugliese
- Lucia Alberghina
- Lucia Leccisotti
- Lucia Rampin
- Luigia Florimonte
- Luis Benitez
- Luis Lumbreras Vega
- Luis Manuel Rochela Vázquez
- Luis Quintana
- Luisa Vera
- Luise Reichmuth
- Luiz Mastrocola
- Lydia Chelghoum
- Lynne Koweek
- Madhu Neupane
- Mady Doucoure
- Magdalena Kostkiewicz
- Magnus Simonsson
- Magnus T Jensen
- Mahmoud Al Heidous
- Mahmoud Sani
- Mahmoud Shaaban
- Mahmud Mossa-Basha
- Mahmut Yüksel
- Maja Franceschi
- Maja Hrabak Paar
- Majid Assadi
- Mallory Balmer-Swain
- Mamoru Nanasato
- Manish Motwani
- Manlio Gerardo Gama-Moreno
- Manuel Barreiro-Perez
- Manuel Cabada
- Manuel Castillo
- Manuel Valencia
- Manuja Premaratne
- Marc Faraggi
- Marcela Redruello
- Marcello Chiocchi
- Marcello Zapparoli
- Marcelo Santos
- Marcelo Silva
- Marcio Sommer Bittencourt
- Marco Gatti
- Marco Guglielmo
- Marcos Montecinos
- Marcus Chen
- Margarita Vakhromeeva
- Margherita Maffione
- Mari Sakanyan
- Maria Eduarda Menezes de Siqueira
- Maria Fernanda Merani
- Maria Helena Albernaz Siqueira
- Maria João Vidigal
- Maria Koutelou
- Maria Luisa De Rimini
- Maria Medus
- Marian Pop
- Marian Vandyck-Acquah
- Mariana Daicz
- Marie Rhiamar Sauler-Gomez
- Marija Vavlukis
- Marika Kalnina
- Marina Garcheva-Tsacheva
- Marina Leitman
- Marina Prpic
- Marina Rodríguez
- Marina Vlajkovic
- Mario Beretta
- Mario Ornelas
- Mark Hamilton
- Mark Hyun
- Mark Rabbat
- Maros Ferencik
- Martin Busk
- Martti Larikka
- Mary Carmen Herrera-Zarza
- Mary Schemmer
- Maryam Tajik
- Maryna Satyr
- Masaki Saito
- Masamichi Imai
- Masanao Naya
- Masao Miyagawa
- Masao Moroi
- Masayoshi Sarai
- Masoud Garashi
- Matteo Bauckneht
- Matthew Budoff
- Matthias Friedrich
- Matthieu Dietz
- Maurizio Dondi
- Mayra Sanchez Velez
- Michael Cahill
- Michael Cheezum
- Michael Chetrit
- Michael Crowley
- Michael Dilorenzo
- Michael Gannon
- Michael Randazzo
- Michael Sobczak
- Michael Spartalis
- Michael Zgaljardic
- Michele Duldulao-Ogbac
- Michelle C Williams
- Mickaël Ohana
- Miguel Kapitan
- Miju Cheon
- Mike Kay
- Mila Uy
- Milan Kaminek
- Ming-Yen Ng
- Mirvat Alasnag
- Mitchell Kaplan
- Mohamad Haidar
- Mohamed Lemine Dieng
- Mohamed Mandour Ali
- Mohammad Ali Khan
- Mohammad Rawashdeh
- Mohammad Saadullah
- Mohan Ashok Kumar
- Mohmmed Nassoh Hafez
- Mokhtar Ridouh
- Mona Bhatia
- Mona Hassan
- Mona Kinkhabwala
- Monika Štalc
- Monvadi Srichai
- Morten Bøttcher
- Moshe Modiselle
- Mostafa Abass
- Mouaz Al-Mallah
- Mrinali Shetty
- Mugisha Julius Sebikali
- Muhammad Babar Imran
- Muhammad Numair Younis
- Murilo Foppa
- Mustafa Murtadha
- Myron Gerson
- Nadia Ismaili Alaoui
- Nadine Kawel-Böhm
- Naghmeh Tebyanian
- Nahla Zeidan
- Nailia Valiullina
- Naima Tag
- Nancy Quachang
- Naoya Matsumoto
- Naresh Kumar Goyal
- Natale Quartuccio
- Natalia Aramayo
- Natalie Rutherford
- Natallia Maroz-Vadalazhskaya
- Nathan Better
- Neiva Maciel
- Nelson Amores
- Nelson Lopez
- Nelsy Coromoto Gonzalez
- Nerisha Govender
- Nicolaj Hansson
- Niels Peter Rønnow Sand
- Niels Van Pelt
- Niki Lama
- Nilesh Banthia
- Nina Gagarina
- Nishant Shah
- Nita Ray Chaudhuri
- Nobuo Iguchi
- Nobuo Tomizawa
- Noor Khairiah A Karim
- Noriko Oyama-Manabe
- Nouzha Ben Rais
- Ntanganedzeni Muambadzi
- Nuno Bettencourt
- Nuno Moreno
- Olga Dariy
- Olga Morozova
- Oliver Sommer
- Omar Farouque
- Omoa Djuraev
- Osama Smettei
- Osamu Manabe
- Osayande Evbuomwan
- Oscar Ulises Preciado-Gutiérrez
- Osvaldo Masoli
- Otto Lang
- Paco Bravo
- Panagiotis Georgoulias
- Paola Anna Erba
- Partha Choudhury
- Parul Mohan
- Parveen Kumar
- Patricia O'Sullivan
- Patricia Rodriguez Lozano
- Patrick Davis
- Paul Thomas
- Paulo Masiero
- Paulo Schvartzman
- Pavlo Korol
- Paz Abrihan
- Pedro Abad
- Peter Burger
- Peter Mcconachie
- Phuoc Minh Hiep Nguyen
- Pierpaolo Alongi
- Prabhjot Nijjar
- Pragya Ranjan
- Prasad Guntur Ramkumar
- Prashant Nagpal
- Pravin Patil
- Prem Soman
- Punit Sharma
- Purvi Parwani
- Purvi Parwani
- Qais Naili
- Qaisar Siraj
- Rachele Bonfiglioli
- Raef Boktor
- Rafael Humberto Morales Murguia
- Rafael Lopes
- Rafael Torres
- Raihan Hussain
- Rajesh Janardhanan
- Ram Ghimire
- Ramanathapuram Parameswaran
- Ramezan Jafari
- Rami Abazid
- Rami Doukky
- Ramon Murgieitio-Cabrera
- Randall Thompson
- Raúl Araujo
- Rebecca Schofield
- Rebecca Seifried
- Reiko Ideguchi
- Renata Komiagiene
- Renée Bullock-Palmer
- Reyhaneh Manafi-Farid
- Ricardo Belisario Castro
- Ricardo Fontes-Carvalho
- Ricardo Geronazzo
- Ricardo Ruano Perez
- Riccardo Liga
- Riemer Slart
- Ripen Kumar Gupta
- Rita Alay
- Rob Beanlands
- Robert Biederman
- Robert Hendel
- Robert Manka
- Robert Miller
- Robert Skotnicki
- Roberta Assante
- Roberta Casoni
- Roberta Delgado
- Roberto Sciagrà
- Roberto Waltrick
- Rodolfo Ferrando
- Rodrigo Cerci
- Rodrigo Cerci
- Ronaldo Lima
- Ronen Goldkorn
- Ronny Ralf Buechel
- Rosanna Morales
- Roxana Campisi
- Ruben Leta
- Rupal O'Quinn
- Ryan Yudistiro
- Ryo Nakazato
- Sabha Bhatti
- Saeed Farzanehfar
- Said Aytani
- Saidur Rahman Khan
- Salah Bouyoucef
- Sameh Elkaffas
- Samer Arnous
- Sandra Abramson
- Sandra Graciela Rosales Uvera
- Sandra Rosales-Uvera
- Sang-Geon Cho
- Santo Dellegrottaglie
- Santosh Singh
- Sara Pacella
- Sarameth Thou
- Sarojini David
- Satoshi Isobe
- Saurav Chatterjee
- Scott Beuzeville
- Scott Bingham
- Scott Jerome
- Sean Blue
- Seth Uretsky
- Shady Abohashem
- Shamil Morayati
- Shankar Vamadevan
- Shantanu Sengupta
- Sharmila Dorbala
- Shashank Jain
- Shazia Fatima
- Shehu Kana
- Sherif Abd Elsamad
- Shigeki Nagamachi
- Shigeru Kiryu
- Shinichiro Fujimoto
- Shinichiro Kumita
- Shinichiro Yamada
- Shinya Shiraishi
- Shinya Yamazaki
- Shivani Pandey
- Shivani Patel
- Shmuel Fuchs
- Sinisa Stankovic
- Sirianong Namwongprom
- So Won Oh
- Soe Myat Win
- Sofia Haider
- Soley Varoeun
- Sonia Merlano-Gaitan
- Sonia Traverso
- Soo Woong Yoo
- Sorin Danciu
- Srikanth Vallurupalli
- Stephen Bloom
- Stephen Horgan
- Stephen Richard Underwood
- Steve Leung
- Stuart More
- Stuart Tie
- Su Thet Oo
- Subodh Joshi
- Subramaniyan Ramanathan
- Sujata Shanbhag
- Sujatha Buddhe
- Sukriti Kumar
- Suliman Suliman
- Susan Buckingham
- Susana Molteni
- Susana Zeffiro
- Søren Hess
- Tadao Aikawa
- Tadhg Gleeson
- Taghreed Abd Alrahman
- Tahir Ahmad
- Taimur Abbasi
- Tairkhan Dautov
- Takao Kato
- Takashi Kawamoto
- Takashi Norikane
- Tanyaluck Thientunyakit
- Tao Li
- Tapan Patel
- Tapati Mandal
- Tatsuya Yoneyama
- Tawika Kaewchur
- Teresa Massardo
- Themissa Voss
- Theodora Benedek
- Theodora Zaglavara
- Thércio Rocha
- Thiago Ferreira de Souza
- Thiri Kyiphyu
- Thomas N B Pascual
- Thomas Semple
- Tiago Senra
- Tiémégna Florence Ouattara
- Tiffany Chen
- Timothy Fairbairn
- Todd C Villines
- Todd Villines
- Tokuo Kasai
- Tomas Zaremba
- Tomasz Urbanik
- Tonci Batinic
- Tong Zhang
- Toral Patel
- Toshiaki Kadokami
- Turki Al Garni
- Tushar Garg
- Uchenna Onubogu
- Uka Geisler
- Uladzimir Tserakhau
- V J Karthikeyan
- Valentin Sinitsyn
- Valentina Soldat-Stankovic
- Valeria Pergola
- Valtteri Uusitalo
- Vassilis Prassopoulos
- Venkatesh Murthy
- Veronica Della Tommasina
- Verónica Vanesa Gómez Leiva
- Victor Hasbani
- Victor Jäger
- Victor Wayne
- Vijay Sai Chowdekar
- Vikas Tandon
- Vikas Verma
- Viktor Pospelov
- Vincent Sorrell
- Vincenzo Russo
- Virginia Garcia Quinto
- Virginia Pubul
- Vittorio Censullo
- Vivaswan Dutt Mishra
- Vivek Bhat
- Viviana Frantellizzi
- Vladimir Kincl
- Vladimir Sergienko
- Wanda Acampa
- Warren Moore
- Wenya Liu
- William DeSisto
- William Duvall
- William Topping
- Wilson Furlan Matos Alves
- Won Jun Kang
- Ximing Wang
- Xuan Canh Nguyen
- Yamilé Peña
- Yan Yi
- Yang Hou
- Yao Lu
- Yariela Herrera Malo
- Yaroslav Pynda
- Yasmin Hamirani
- Yassine Martinez
- Yasushi Wakabayashi
- Yasutaka Ichikawa
- Yasutoshi Ohta
- Yasuyo Taniguchi
- Yeon-Koo Kang
- Yiannis Chatzizisis
- Yining Wang
- Yoav Arnson
- Yoichi Otomi
- Yong Hyu Jeong
- Yosef Cohen
- Yoshimitsu Fukushima
- Young So
- Younghoon Kwon
- Yu Izawa
- Yunqiang An
- Zabah Jawa
- Zhaoqian Wang
- Zhuoran Xu
- Zorana Mrsic
- Zuzana Berecova
- Publication venue
- Publication date
- 01/01/2022
- Field of study
BACKGROUND The extent to which health care systems have adapted to the COVID-19 pandemic to provide necessary cardiac diagnostic services is unknown.OBJECTIVES The aim of this study was to determine the impact of the pandemic on cardiac testing practices, volumes and types of diagnostic services, and perceived psychological stress to health care providers worldwide.METHODS The International Atomic Energy Agency conducted a worldwide survey assessing alterations from baseline in cardiovascular diagnostic care at the pandemic's onset and 1 year later. Multivariable regression was used to determine factors associated with procedure volume recovery.RESULTS Surveys were submitted from 669 centers in 107 countries. Worldwide reduction in cardiac procedure volumes of 64% from March 2019 to April 2020 recovered by April 2021 in high- and upper middle-income countries (recovery rates of 108% and 99%) but remained depressed in lower middle- and low-income countries (46% and 30% recovery). Although stress testing was used 12% less frequently in 2021 than in 2019, coronary computed tomographic angiography was used 14% more, a trend also seen for other advanced cardiac imaging modalities (positron emission tomography and magnetic resonance; 22%-25% increases). Pandemic-related psychological stress was estimated to have affected nearly 40% of staff, impacting patient care at 78% of sites. In multivariable regression, only lower-income status and physicians' psychological stress were significant in predicting recovery of cardiac testing.CONCLUSIONS Cardiac diagnostic testing has yet to recover to prepandemic levels in lower-income countries. Worldwide, the decrease in standard stress testing is offset by greater use of advanced cardiac imaging modalities. Pandemic-related psychological stress among providers is widespread and associated with poor recovery of cardiac testing. (C) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
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- Chowdhury Sharfuddin M
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- en Siew Bei
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- Felix Michael Shalzim
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- Wright Jonathan
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- Yadav Ram Kishan
- Yadev I P
- Yague Julio
- Yakout Nadia
- Yakunina Natalia
- Yalkin Ömer
- Yanishev Alexey
- Yao Hongwei
- Yazici Pinar
- Yemez Kursat
- Yew Chor Kuan
- Yiğit Direnç
- Yılmaz Gülseren
- Yilmazlar Tuncay
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
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- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
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- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
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- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
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- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
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- Al-Himyari Hamza S.
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- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
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- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
- Bartosiak Katarzyna
- Basarab Maksym
- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
- Bath Michael
- Beattie Miriam
- Bedada Alemayehu Ginbo
- Belais Fanny
- Belal qadomi Asef
- Belev Nikolay
- Belli Andrea
- Beltrán de Heredia Juan
- Belvedere Angela
- Ben Dallah Najah
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- Bengur Fuat Baris
- Benkabbou Amine
- Benke Marton
- Benyaiche Chaymae
- Bergeat Damien
- Bernstein Mitchell
- Beshtawi Doha
- Besli Sevval
- Beuran Mircea
- Bhandare Manish
- Bhangu Aneel
- Bhatti Muhammad Iqbal
- Bianchini Stefania
- Bianco Francesco
- Bibas Fatma
- Biccard Bruce M
- Bielosludtsev Oleksii
- Bienfait Mumbere
- Billy Matthew
- Bin Mohamad Sithik Muhammad Navid
- Binetti Margherita
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- Blunnie Eimear
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- Bogusevicius Algirdas
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- Borghi Felice
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- Borowski David W
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- Doherty Ronan J
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- Dominguez Joaquina
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- Donaldson Rachel
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- Dousset Bertrand
- Draganic Brian
- Drake Thomas M
- Drane Andrew
- Duarte Marina
- Dudi-Venkata Nagendra Naidu
- Duggan William
- Duke Kathryn
- Duller Alexander
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- Dworak Jadwiga
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- Eismontas Vitalijus
- Eklöv Karolina
- Ekpete Ogbonnia
- Ekwen Gerald
- El Aroussi Nouhaila
- El Gharmoul Tasnim
- El Jamassi Alaa
- El Muhtaseb M.S.
- El Nakeeb Ayman
- El sheikh Enas
- El Zoghby Naira
- El-Kahlout Sahar
- El-remaily Amira
- El-Sawy Aya
- El-taweel Alaa
- Elazab Yasmin
- Elbarouni Sofian
- Elbealawy Mohamed
- Elbeshina Aya Elseed
- Elblbessy Mahmood
- Eldeep Ahmed
- Eldeep Mostafa
- Eldmaty Asmaa
- Eldoseuky mohammed Amany
- Elemile Peter
- Elewaily Mohamed Ibrahim Elsayed
- Elfaituri Taha
- Elfallal Ahmed
- Elfanty Mahmoud
- ElFayoumy Ahmed Moustafa
- Elfeki Hossam
- Elfizri Zatira
- Elgammudi Mala
- Elghareeb Nourhan
- Elhadi Ahmed
- Elhadi Muhammed
- Elhajjaji Yasmine
- Elhelow Esraa
- Elhout Somaya
- Elkabir Osama
- Elkhadragy Ahmed
- Elkhalawy Aya
- Ellaby-Hall Jordan
- Ellul Sarah
- Elmahdy Marwa
- Elmeslemany Nehal
- Elmokadem Aya
- Elqadi Muawiyah
- Elrais Safa
- Elsayed Mai
- Elsayed Mohammad
- Elshafei Houssein
- Elshafey Ahmed
- Elshaibani Mahmoud
- Elshatby Bassant
- Elshawy Mohamed Elemam
- Elsherbeny Mohammed Yasser
- Elsherif Fawzia
- Elshimy Ahmed
- Elsobky Hager
- Elteir Hana
- Eltoum Ruba
- Elzanfaly Ali Abdelazez
- Emara Eman
- Emeghara Okechukwu
- Emile Sameh
- Enumah Zachary
- Eraslan Huseyin
- Eray Ismail Cem
- Erkul Oğuz
- Esbaga Fatima
- Escobar Dennis
- Escrevente Ricardo
- Eskander John
- Eslam Sara
- Esmat Nourhan Ahmed
- Esper Asil
- Espin-Basany Eloy
- Espina Perez Beatriz
- Espinosa-Bravo Martin
- Esposito Giovanni
- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
- Essam Eman
- Estalagem Inês
- Estevez Tesouro José
- Eswaye Haitem
- Etchill Eric
- Etonyeaku Amarachukwu
- Eusebio Zegarra Ivan Edward
- Ezzat Helmy
- Fadel Ahmed
- Fahira Alessa
- Fahmawee Toqa
- Fairfield Cameron J
- Falato Armando
- Falco Giuseppe
- Falco Nicolò
- Fareleira Ana
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- Winter Des
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- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Wong Michael Pak-Kai
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- Wong Tsz Lun Ernest
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- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
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- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
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- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
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- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
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- Yozgatli Tahir Koray
- Yu Kristin
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- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research